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Why do people infected with the human immunodeficiency virus (HIV) often suffer from cardiovascular, liver, and other comorbidities? Researchers at the Centre for Individualised Infection Medicine (CiiM) investigated this question as part of the 2000HIV study, a multi-omics cohort coordinated by several research centers in the Netherlands. They identified various molecules and mechanisms that could be linked to the development of these comorbidities. The scientists are making the extensive results of their study freely available. They hope that they will be used for new research approaches and lead to a better understanding of the underlying causes and to helpful therapies. The researchers have now published their study results in the journal Nature Medicine. The CiiM is a joint institution of the Helmholtz Centre for Infection Research (HZI) and Hannover Medical School (MHH).

21.08.2025

CiiM

News

The former President of Hannover Medical School (MHH) and Clinical Director of the Helmholtz Centre for Infection Research (HZI), Prof. Michael P. Manns, passed away on 15 August 2025. Manns succumbed to a tumor disease at the age of 73. As a renowned gastroenterologist, he belonged to the worldwide scientific elite, was one of the most cited scientists, and enriched both the German and international research landscape as an excellent communicator. Until the very end, Manns was still actively involved in research at the MHH and promoted the scientific organization of the Centre for Individualised Infection Medicine (CiiM), a joint institution of the HZI and the MHH, which he co-founded. Manns also supported another joint center of the HZI and MHH, the TWINCORE, with his extensive expertise.

18.08.2025

CiiM

Electron micrograph of Klebsiella oxytoca

News

A balanced gut microbiome not only contributes to digestion, but is also an important protective factor against infections. Researchers at the Helmholtz Centre for Infection Research (HZI) led by Prof. Till Strowig, scientist in the German Center for Infection Research (DZIF), want to harness the power of the microbiome to prevent serious infections. They have discovered that bacteria of the species Klebsiella oxytoca can displace pathogenic bacteria from the gut and want to develop a living biotherapeutic based on this finding. The DZIF is now providing 2.2 million euros in funding for product development until the first tests on humans.

07.08.2025

HZI Campus

HIOH

News

Since the start of the SARS-CoV-2 pandemic, several variants of the virus have developed into Variants of Concern (VOCs), as classified by the World Health Organization (WHO). VOCs are virus variants that are predicted or known to cause large waves of infections due to their altered phenotypic characteristics and with risk of altering disease severity, reducing vaccine effectiveness or otherwise leading to increased burden of health care systems. Researchers at the Helmholtz Centre for Infection Research (HZI) and the German Center for Infection Research (DZIF) have developed an analysis method to detect VOC early in their development. The study was published in the journal Nature Communications.

22.07.2025

HZI Campus

BRICS

Richmond Sarpong with certificate in hand, next to him is Klemens Rottner

News

The Friends of the Helmholtz Centre for Infection Research (HZI) in Braunschweig and the Technische Universität Braunschweig are awarding Prof. Richmond Sarpong from the University of California, Berkeley, with the Inhoffen Medal 2025. Sarpong is an eminent organic chemist who has distinguished himself through particular successes in synthetic chemistry and method development. The award ceremony took place on July 10, 2025 at the HZI in Braunschweig.

11.07.2025

HZI Campus

CiiM

HIRI

News

The German Research Foundation (DFG) is funding the DEEP-DV research group for another four years with a total of €5.3 million. This marks the second phase of the successful work of the interdisciplinary group, which includes scientists from Braunschweig, Hamburg, Hannover, Berlin, Regensburg, Ulm, Freiburg, and Munich. DNA viruses such as herpes viruses and polyomaviruses can remain in the body permanently after an initial infection and cause serious health consequences years later.

10.07.2025

HZI Campus

HZI in the media

... er Klinischer Direktor des Helmholz Zentrums für Infektionsforschung (HZI) und Gründungsdirektor des Zentrums für Individualisierte ...

21.08.2025

Deutsche Gesellschaft für Innere Medizin e.V.

Nature Medicine

. The CiiM is a joint institution of the Helmholtz Center for Infection Research (HZI) and Hannover Medical School (MHH).

21.08.2025

Medical Xpress

und damit einhergehenden Erkrankungen zu sein.“

Helmholtz-Zentrum für Infektionsforschung

Originalpublikation:

J. Botey-Bataller, N. van

21.08.2025

Verband Deutscher Biologen e.V.

Now, a team of researchers, led by scientists from the Helmholtz Centre for Infection Research in Germany, has reported that a gene in the

21.08.2025

The Hindu

Cicin-Sain, a viral immunologist at Germany's Helmholtz Centre for Infection Research, is leading the development of a respiratory syncytial

16.08.2025

The Times of India

Instituts für Pharmazeutische Forschung Saarland (HIPS), einem gemeinsamen Standort des Helmholtz-Zentrums für Infektionsforschung (HZI) ...

15.08.2025

Springer Medizin

... Einrichtung betreiben die MHH und das Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig gemeinsam.

In seine ...

15.08.2025

Neue Presse (Hannover)

Medicine Bundesamt für Verbraucherschutz und Lebensmittelsicherheit Helmholtz-Zentrum für Infektionsforschung ARD alpha Universität Würzburg

13.08.2025

Brisant

... Prof. Dr. rer. nat. Dunja Bruder, Helmholtz-Zentrum für Infektionsforschung, Braunschweig und Institut für Med. Mikrobiologie ...

12.08.2025

Deutsches Ärzteblatt

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