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Futuristic stock photo: Doctor pressing AI button

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The Helmholtz Association is kicking off 2026 with new research initiatives on strategic future topics to bring technological breakthroughs into practical application more quickly. The Helmholtz initiatives “Biomedical Engineering Initiative,” “Water Safety and Security Initiative,” and “Quantum Use Challenge” are generating innovative solutions – from needle-free blood glucose measurement via wearables to quantum sensors for more powerful batteries and innovative concepts for water management in large cities. The initiatives are being developed in close cooperation with partners from politics, business, and society and address key technologies and strategic research areas of the German government’s High-Tech Agenda. Four projects of the Helmholtz Centre for Infection Research (HZI) and its sites in Greifswald, Saarbrücken and Würzburg are part of the new research campaigns.

22.01.2026

HZI Campus

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Person wearing purple gloves performing chemical synthesis

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For decades, tuberculosis (TB) has been one of the deadliest infectious diseases worldwide. Resistant strains of Mycobacterium tuberculosis are particularly problematic, as many established drugs are becoming increasingly ineffective against them. However, a research team from the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) and Saarland University has now discovered a new family of natural substances that exhibit excellent activity against the TB pathogen. They have also investigated these substances so comprehensively that targeted further development is possible for the first time. The researchers have now published their findings in the journal Angewandte Chemie International Edition.

21.01.2026

HIPS

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Two collaborative projects involving the Helmholtz Centre for Infection Research (HZI) are being funded with 100,000 euros each from the joint program "zukunft.niedersachsen" of the state of Lower Saxony and the Volkswagen Foundation. Both projects result from the collaboration between HZI and the MRC–University of Glasgow Centre for Virus Research (CVR), established in 2024 as part of a cooperation between the Helmholtz Association and the British Medical Research Council (MRC). The funded MARITH project will grow organoids from throat tonsil tissue to study the development of immunological memory in humans, while the ViReST project analyzes the sites of viral replication in respiratory infections and their impact on virus transmission.

20.01.2026

HZI Campus

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The global skin care company Beiersdorf and the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) have entered into a long-term, exclusive partnership. In this collaboration they aim to investigate the role of the skin microbiome in maintaining healthy skin. The goal is to identify natural products produced by microorganisms on the skin that have a positive effect on skin balance. The project is based on extensive data sets on microorganisms that inhabit human skin.

13.01.2026

HIPS

Cryo-electron microscope image of the nuclease Cas12a3 with illustrated scissors

News

The CRISPR “gene scissors” have become an important basis for genome-editing technologies in many fields, ranging from biology and medicine to agriculture and industry. A team from the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg has now demonstrated that these CRISPR-Cas systems are even more versatile than previously thought. In cooperation with the Helmholtz Centre for Infection Research (HZI) in Braunschweig and Utah State University (USU) in Logan (USA), the scientists have discovered a novel CRISPR defense mechanism: Unlike known nucleases, Cas12a3 specifically destroys transfer ribonucleic acids (tRNA) that are vital for protein production to shut down infected cells. The team published its findings today in the journal Nature.

07.01.2026

HZI Campus

HIRI

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The gene scissors CRISPR-Cas are an important tool for genome editing. However, their functionality is limited because they rely on specific sequences to operate. Their ancient ancestors, on the other hand, may have been much more versatile. Rediscovering their forgotten abilities and harnessing them for biotechnological applications is the goal of the “RGNcestry” research project led by Chase Beisel, affiliated department head at the Helmholtz Institute for RNA-based Infection Research (HIRI). The European Research Council (ERC) is funding the project with ten million euros over a period of six years.

23.12.2025

HIRI

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HZI in the media

... fünf Teams durch, darunter PROTON vom Helmholtz-Zentrum für Infektionsforschung. Dieses entwickelt einen neuartigen Wirkstoff gegen ...

22.03.2026

Ad Hoc News

Vor allem durch die Coronapandemie sind Forschende des Helmholtz-Zentrums für Infektionsforschung in den vergangenen Jahren bundesweit bekannt geworden. Auf welche Themen die Einrichtung für die Zukunft setzt.

20.03.2026

Deutsches Ärzteblatt

... beschäftigt sich daneben unter dem Dach des Helmholtz Institutes für Pharmazeutische Forschung Saarland (HIPS) ...

18.03.2026

Biermann Medizin

... Ausbau von Produktions- und Vermarktungskapazitäten.

Das Helmholtz-Zentrum für Infektionsforschung HZI begrüßt den Erhalt der GMP- ...

18.03.2026

Bionity.COM

... der Universität zu Lübeck, des Helmholtz-Zentrums für Infektionsforschung (HZI) in Braunschweig, der Medizinischen Hochschule Hannover ...

17.03.2026

Biermann Medizin

Vorsorge Das Coronavirus hält die Welt nicht mehr in Atem. Doch was, wenn ein anderer gefährlicher Erreger auftaucht? So wappnet sich unser Gesundheitssystem

16.03.2026

Apotheken Umschau

... stumpfen ab“, erklärt Marc Brönstrup vom Helmholtz-Zentrum für Infektionsforschung in Braunschweig. Neue Antibiotika sind dringend ...

14.03.2026

ARD Mediathek

... der Medizinischen Hochschule Hannover und dem Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig neue Wirkstoffe ...

13.03.2026

MTA Dialog

... späten 1990ern hob sie der am Saarbrücker Helmholtz-Institut für Pharmazeutische Forschung Saarland (HIPS) tätige ...

08.03.2026

Saarbrücker Zeitung

European institutions, including Germany’s Helmholtz Institute for RNA-based Infection Research, Helmholtz Center for Infection Research,

06.03.2026

Clinical Lab Products

Die Zellen kontrollieren die Reaktion des Immunsystems und verhindern Schäden durch Selbstangriffe. Forschende arbeiten daran, sie zur Therapie einzusetzen.

05.03.2026

NDR Norddeutscher Rundfunk

Nachwuchsgruppe „Nanoinfektionsbiologie“ am HZI. Diese Lücke soll das Projekt ONEMUC (Respiratorischer Mukus als One Health-Schnittstelle) ...

03.03.2026

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