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New, resistance-breaking drugs are urgently needed to effectively treat infections with antibiotic-resistant germs in the future. Researchers from Saarbrücken and Vienna have now found a possible starting point for the development of such drugs in the natural product Saarvienin A. This novel molecule is capable of killing bacteria even if they are already resistant to clinically used antibiotics. The researchers published their findings in the journal Angewandte Chemie International Edition.
28.05.2025
HZI podcast "InFact" with Theresa Graalmann on the topic autoimmune diseases
News
When our immune system chooses the wrong enemy and turns against our own body, autoimmune diseases can result. Dr. Dr. Theresa Graalmann is a physician and clinician scientist who heads the junior research group “Translational Immunology” at TWINCORE – Center for Experimental and Clinical Infection Research. In this episode of the HZI podcast InFact, she explains how rheumatism, lupus, and vascular inflammation develop and how doctors and scientists work together to incorporate patient data and state-of-the-art cell analyses directly into the development of new therapeutic approaches.
27.05.2025
Study authors Maureen Obara and Dr Matthias Bruhn
News
Monoclonal antibodies against SARS-CoV-2 were considered a promising approach for the prevention and therapy of corona virus infections. However, the ongoing evolution of the virus regularly produces new variants that are no longer neutralized by the antibodies. Researchers from TWINCORE, together with partners from Hanover and Bern, have now been able to clarify the underlying mechanism in more detail. The TWINCORE is a joint institution of the Helmholtz Centre for Infection Research (HZI) in Braunschweig and Hannover Medical School (MHH). Instead of using a single antibody, they propose the combination of several antibodies for treatment. They have published their findings in the scientific journal eBioMedicine.
26.05.2025
Group photo
News
Decisions have been made on future Clusters of Excellence in the second round of competition under the Excellence Strategy – the joint initiative of the federal and state governments to further strengthen top-level research at universities in Germany. The Helmholtz Centre for Infection Research (HZI) is part of two of the funded Clusters of Excellence together with university partners: RESIST and NUCLEATE. RESIST at Hannover Medical School (MHH) will receive funding for another seven years. In this cluster, scientists are investigating how people who are susceptible to infection can be better protected. In the newly approved NUCLEATE cluster at the Julius-Maximilians-Universität Würzburg (JMU) with the Technical University of Munich and the Ludwig-Maximilians-Universität München, group leaders from the Helmholtz Institute for RNA-based Infection Research (HIRI), a site of the HZI in cooperation with the JMU, are conducting research into nucleic acid-based therapies. A total of 70 Clusters of Excellence were selected for funding.
26.05.2025
Close-up of bat
News
Bats are known as natural hosts for highly pathogenic viruses such as MERS- and SARS-related coronaviruses, as well as the Marburg and Nipah viruses. In contrast to the severe and often fatal disease outcomes these viruses cause in humans, bats generally do not show obvious signs of viral illness following infection. An international research team led by Dr. Max Kellner and Prof. Josef Penninger, Scientific Director of the Helmholtz Centre for Infection Research (HZI), has developed an innovative organoid research platform that allowed them to closely investigate the cellular antiviral defense mechanisms of mucosal epithelial tissues of bats. The results have now been published in Nature Immunology and could pave the way for the development of new therapies against viral diseases.
21.05.2025
Group photo ENDURIVAC
News
Yesterday, the biomedical project forge of the state of Lower Saxony reviewed the most promising ideas from across the region and selected the winners: At the fourth portfolio conference of the Institute for Biomedical Translation (IBT) Lower Saxony, a high-caliber jury selected projects from the Helmholtz Centre for Infection Research (HZI) in Braunschweig, the University Medical Center Göttingen (UMG) and TWINCORE - Centre for Experimental and Clinical Infection Research, which will receive funding of almost 3 million euros. TWINCORE is a joint institution of the HZI and Hannover Medical School (MHH). A total of 25 million euros will be available to the IBT Lower Saxony until 2028 to accelerate the transfer of cutting-edge research in the life sciences in Lower Saxony and bring it to the world in the form of start-ups and entrepreneurial ideas.
14.05.2025

HZI in the media

... Brinkmann (Archivbild): Die Virologin forscht am Helmholtz-Zentrum für Infektionsforschung in Braunschweig. (Quelle: teutopress/ ...

11.07.2025
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t-online.de

... des HZI, der Technischen Universität Braunschweig und des Fördervereins des HZI.

 

Promotionspreise des HZI

 

Der ...

11.07.2025
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Regional Heute

... lassen. Ein weiterer Partner ist das Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig. Finanziert wird das ...

07.07.2025
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MDR

... Pneumologie an der UMMD sowie dem Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig. Gefährliche Folgeinfektion mit ...

06.07.2025
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Magdeburger News

... von der Abteilung Mikrobielle Immunregulation am Helmholtz-Zentrum für Infektionsforschung (HZI) in einer Pressemitteilung des ...

04.07.2025
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Pharmazeutische Zeitung

In a groundbreaking new study, researchers from the Helmholtz Center for Infection Research (HZI) and Hannover Medical School (MHH) have

04.07.2025
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Maldankon

removed from the gut?

 

Researchers from the Helmholtz Center for Infection Research (HZI), in collaboration with researchers from Hannover

03.07.2025
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Phys.org

Würzburg – Eine Arbeitsgruppe des Würzburger Helmholtz-Instituts für RNA-basierte Infektionsforschung (HIRI) sowie aus Schweden und ...

03.07.2025
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Deutsches Ärzteblatt

An international research team led by the Helmholtz Center for Infection Research (HZI) has discovered a new strategy used by the human

02.07.2025
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MSN.com

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