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A recent study led by the Centre for Individualised Infection Medicine (CiiM) and the Radboud University Medical Center published in Genome Biology shows that BCG vaccination does more than fend off tuberculosis - it leaves enduring chemical marks on immune cells that boost responses to various pathogens. Researchers also uncover hormone‑immune crosstalk and sex‑specific effects that could guide next‑generation, individualised vaccine design.

10.07.2025

CiiM

[Translate to English:] Empfangsschild des Arabuko-Sokoke-Nationalparks

Story

Natural substances are an important source of active ingredients used in medicine. However, the chemical diversity of fungi in particular has not yet been sufficiently researched. The EU project Mycobiomics, coordinated by Marc Stadler, Head of the Department “Microbial Drugs” at the Helmholtz Centre for Infection Research (HZI), is investigating the biodiversity of fungi in Europe, Asia and Africa in order to identify pharmaceutically valuable secondary metabolites. In May and June 2025, project participants met in Kenya and South Africa for an expedition and a subsequent symposium.

09.07.2025

HZI Campus

The One Health Surveillance team from HIOH receives the award for “Best Research Environment 2024”.

News

Excellent conditions for research, an inspiring atmosphere and fair cooperation: for all this, the research group “One Health Surveillance” (OHS) at the Helmholtz Institute for One Health (HIOH) has been awarded the “Best Research Environment 2024” prize by the Junge Akademie. Under the leadership of Dr. Fee Zimmermann, the OHS group is establishing health and environmental observatories, so-called “One Health Exploratories”, which collect long-term and systematic data on the health of humans, animals and the environment and integrate it into a big picture. The HIOH is a site of the Helmholtz Centre for Infection Research (HZI) in Braunschweig in cooperation with the University of Greifswald, the University Medicine Greifswald and the Friedrich-Loeffler-Institut.

09.07.2025

HIOH

Electron micrograph of coccal bacteria growing in chains

News

Influenza viruses can trigger epigenetic changes in the alveolar epithelium, the cell layer that lines the alveoli, permanent changes in gene activity without changing the DNA itself. These changes have a lasting effect on subsequent immune responses and result in the body no longer being able to react appropriately to the bacterial pathogens in the event of a subsequent infection with pneumococci. A research team at the Helmholtz Centre for Infection Research (HZI) and the University Hospital Magdeburg (UMMD) has published new findings on the long-term consequences of an influenza A infection in a mouse model in the journal Cell Communication and Signaling.

04.07.2025

HZI Campus

Preparing for historical specimen sampling

Story

From 4 to 6 June 2025, the Department “Pathogen Evolution” led by Prof. Dr. Sébastien Calvignac-Spencer at the Helmholtz Institute for One Health (HIOH) conducted a combined retreat and sampling mission at the Institute of Pathology of the University of Veterinary Medicine Vienna — a key collaboration partner for accessing and studying historical pathological specimens in veterinary medicine. HIOH is a site of the Helmholtz Centre for Infection Research (HZI). The visit focused on collecting around 60 historical tissue samples for molecular genetic analyses related to animal disease research, while also offering time for internal discussions on lab optimization, project development, and team building.

03.07.2025

HIOH

News

If an intestinal inhabitant such as the bacterium Escherichia coli (E. coli) becomes resistant to many antibiotics, it can cause serious health problems if it enters the bloodstream. How can such potentially dangerous multi-resistant bacteria be effectively removed from the gut? Researchers from the Helmholtz Centre for Infection Research (HZI), in collaboration with researchers from Hannover Medical School (MHH), explored this question in their latest study.

03.07.2025

HZI Campus

HZI in the media

... er Klinischer Direktor des Helmholz Zentrums für Infektionsforschung (HZI) und Gründungsdirektor des Zentrums für Individualisierte ...

21.08.2025

Deutsche Gesellschaft für Innere Medizin e.V.

Nature Medicine

. The CiiM is a joint institution of the Helmholtz Center for Infection Research (HZI) and Hannover Medical School (MHH).

21.08.2025

Medical Xpress

und damit einhergehenden Erkrankungen zu sein.“

Helmholtz-Zentrum für Infektionsforschung

Originalpublikation:

J. Botey-Bataller, N. van

21.08.2025

Verband Deutscher Biologen e.V.

Now, a team of researchers, led by scientists from the Helmholtz Centre for Infection Research in Germany, has reported that a gene in the

21.08.2025

The Hindu

Cicin-Sain, a viral immunologist at Germany's Helmholtz Centre for Infection Research, is leading the development of a respiratory syncytial

16.08.2025

The Times of India

Instituts für Pharmazeutische Forschung Saarland (HIPS), einem gemeinsamen Standort des Helmholtz-Zentrums für Infektionsforschung (HZI) ...

15.08.2025

Springer Medizin

... Einrichtung betreiben die MHH und das Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig gemeinsam.

In seine ...

15.08.2025

Neue Presse (Hannover)

Medicine Bundesamt für Verbraucherschutz und Lebensmittelsicherheit Helmholtz-Zentrum für Infektionsforschung ARD alpha Universität Würzburg

13.08.2025

Brisant

... Prof. Dr. rer. nat. Dunja Bruder, Helmholtz-Zentrum für Infektionsforschung, Braunschweig und Institut für Med. Mikrobiologie ...

12.08.2025

Deutsches Ärzteblatt

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