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NEWS
HZI appoints Fabian Leendertz as founding director of the Helmholtz Institute for One Health
A new location of the Helmholtz Centre for Infection Research is being built in Greifswald
VIDEO
How is the HZI contributing to the management of the coronavirus pandemic?
Three HZI scientists present their research project on SARS-CoV-2
STORY
World Day for Laboratory Animals on April 24
The HZI has set itself the goal of finding new diagnostic methods, new active substances and new therapies against infectious diseases. Here you can find out why we cannot forgo animal experiments in our research.
STORY
New viruses, new challenges
There are many thousands of viruses circulating in the animal world that could spread to humans. SARS-CoV-2 has shown how quickly new viruses can spread worldwide.
NEWS
Putting pathogens on mute
Saarbrücken researchers develop novel strategy for treating hospital germs
NEWS
Extensive data resource for microbiome research
HZI bioinformaticians bring to light a natural CRISPR system of the human microbiome
NEWS
Molecular weapon with built-in delivery device
HZI scientists find novel protein structures in a bacterial toxin

Overview of vaccination and the vaccine research at HZI

Contact person management in the context of the SARS-CoV-2 pandemic

Tweets by Helmholtz_HZI

Information on the nationwide antibody study

Researcher examines a laboratory sample.

The topics of our research groups and background information on the strategy of the HZI

Researcher in the laboratory with protective equipment.

You can support our research to study the coronavirus and to overcome the pandemic

InFact cover picture with Covid-19 warning sign.

Portraits, reports and interviews - in German and English language

Exterior view of the HZI building in good weather.

Well networked: The HZI locations at a glance

Researcher in the laboratory during a project implementation.

Current vacancies and doctoral positions in our research center

Selected Publications

A list of all publications can be found in our publication database.

All Publications

Wellhöner, F. Döscher, N. Woelfl, F. Vital, M. Plumeier, I. Kahl, S. Potthoff, A. Manns, M.P. Pieper, D.H. Cornberg, M. Wedemeyer, H. Heidrich, B.

Eradication of chronic HCV infection: improvement of dysbiosis only in patients without liver cirrhosis
Hepatology, 0270-9139 (2021)
Priesemann, V. Balling, R. Brinkmann, M.M. Ciesek, S. Czypionka, T. Eckerle, I. Giordano, G. Hanson, C. Hel, Z. Hotulainen, P. Klimek, P. Nassehi, A. Peichl, A. Perc, M. Petelos, E. Prainsack, B. Szczurek, E.

An action plan for pan-European defence against new SARS-CoV-2 variants
Lancet, 0140-6736 (2021)
Dudeck, J. Kotrba, J. Immler, R. Hoffmann, A. Voss, M. Alexaki, V.I. Morton, L. Jahn, S.R. Katsoulis-Dimitriou, K. Winzer, S. Kollias, G. Fischer, T. Nedospasov, S.A. Dunay, I.R. Chavakis, T. Müller, A.J. Schraven, B. Sperandio, M. Dudeck, A.

Directional mast cell degranulation of tumor necrosis factor into blood vessels primes neutrophil extravasation
Immunity., 1074-7613 (2021)
Bonifacius, A. Tischer-Zimmermann, S. Dragon, A.C. Gussarow, D. Vogel, A. Krettek, U. Gödecke, N. Yilmaz, M. Kraft, A.R.M. Hoeper, M.M. Pink, I. Schmidt, J.J. Li, Y. Welte, T. Maecker-Kolhoff, B. Martens, J. Berger, M.M. Lobenwein, C. Stankov, M.V. Cornberg, M. David, S. [...]

COVID-19 immune signatures reveal stable antiviral Tcell function despite declining humoral responses
Immunity., 1074-7613 (2021)
Roth, S. Cao, J. Singh, V. Tiedt, S. Hundeshagen, G. Li, T. Boehme, J.D. Chauhan, D. Zhu, J. Ricci, A. Gorka, O. Asare, Y. Yang, J. Lopez, M.S. Rehberg, M. Bruder, D. Zhang, S. Groß, O. Dichgans, M. Hornung, V. Liesz, A.

Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade
Immunity., 1074-7613 (2021)
Song, Y. Shan, L. Gbyli, R. Liu, W. Strowig, T. Patel, A. Fu, X. Wang, X. Xu, M.L. Gao, Y. Qin, A. Bruscia, E.M. Tebaldi, T. Biancon, G. Mamillapalli, P. Urbonas, D. Eynon, E. Gonzalez, D.G. Chen, J. Krause, D.S. Alderman, J. Halene, S. Flavell, R.A.

Combined liver-cytokine humanization comes to the rescue of circulating human red blood cells
Science, 0036-8075 (2021)
Rajewsky, N. Almouzni, G. Gorski, S.A. Aerts, S. Amit, I. Bertero, M.G. Bock, C. Bredenoord, A.L. Cavalli, G. Chiocca, S. Clevers, H. De Strooper, B. Eggert, A. Ellenberg, J. Fern b ndez, X.M. Figlerowicz, M. Gasser, S.M. Hubner, N. Kjems, J. Knoblich, J.A. Krabbe, G. Li [...]

Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (Nature, (2020), 587, 7834, (377-386), 10.1038/s41586-020-2715-9)
Nature, 00280836 (ISSN) (2021)
Delacher, M. Simon, M. Sanderink, L. Hotz-Wagenblatt, A. Wuttke, M. Schambeck, K. Schmidleithner, L. Bittner, S. Pant, A. Ritter, U. Hehlgans, T. Riegel, D. Schneider, V. Groeber-Becker, F.K. Eigenberger, A. Gebhard, C. Strieder, N. Fischer, A. Rehli, M. Hoffmann, P. Ed [...]

Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
Immunity, 1074-7613 (2021)
Priesemann, V. Brinkmann, M.M. Ciesek, S. Cuschieri, S. Czypionka, T. Giordano, G. Hanson, C. Hens, N. Iftekhar, E. Klimek, P. Kretzschmar, M. Peichl, A. Perc, M. Sannino, F. Schernhammer, E. Schmidt, A. Staines, A. Szczurek, E.

Call for a pan-European COVID-19 response must be comprehensive - Authors' reply
Lancet, 0140-6736 (2021)
Liu, J.K. Maharachchikumbura, S.S.N. McKenzie, E.H.C. Cai, L. Bhat, J.D. Jones, E.B.G. Stadler, M.

Special issue: a tribute to Kevin D. Hyde on his 65th birthday
Fungal Diversity, 15602745 (ISSN) (2021)

Donations

The Strategy of the HZI

Research report 2018/2019

Working at the HZI

The HZI in social networks

Feature: Coronaviruses

SARS-CoV-2 / COVID-19

COVID-19 Vaccine

SORMAS

Antibody study

Research

Donation

InFact - the HZI magazine

Locations

Jobs

Selected Publications

Eradication of chronic HCV infection: improvement of dysbiosis only in patients without liver cirrhosis

An action plan for pan-European defence against new SARS-CoV-2 variants

Directional mast cell degranulation of tumor necrosis factor into blood vessels primes neutrophil extravasation

COVID-19 immune signatures reveal stable antiviral Tcell function despite declining humoral responses

Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade

Combined liver-cytokine humanization comes to the rescue of circulating human red blood cells

Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (Nature, (2020), 587, 7834, (377-386), 10.1038/s41586-020-2715-9)

Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

Call for a pan-European COVID-19 response must be comprehensive - Authors' reply

Special issue: a tribute to Kevin D. Hyde on his 65th birthday