Home | | Helmholtz Centre for Infection Research

NEWS
A virus lurking in the connective tissue
Study by the HZI shows how a herpesvirus on the one hand rests inactive in connective tissue cells and on the other hand can replicate in the same cells when needed
NEWS
Novel candidate drug against persistent intestinal pathogen
New HZI study shows efficacy of the natural product chlorotonil A against dormant stages of the Clostridioides difficile bacterium
NEWS
Bacterial weapons against viral diseases
Discovery of two novel classes of natural products with activity against RNA viruses
NEWS
Sugar-based inhibitors disarm the pathogen Pseudomonas aeruginosa
HIPS researchers develop promising active ingredient to combat multi-resistant bacteria

Portraits, reports and interviews - in German and English language

World Day for Laboratory Animals and Alternative Models on April 24

Tweets by Helmholtz_HZI

Overview of vaccination and the vaccine research at HZI

National Alliance for Pandemic Therapeutic (NA-PATH)

Researcher in the laboratory with protective equipment.

You can support our research to study the coronavirus and to overcome the pandemic

Researcher examines a laboratory sample.

The topics of our research groups and background information on the strategy of the HZI

Exterior view of the HZI building in good weather.

Well networked: The HZI locations at a glance

Researcher in the laboratory during a project implementation.

Current vacancies and doctoral positions in our research center

Selected Publications

A list of all publications can be found in our publication database.

All Publications

Wagner, V. Kern, F. Hahn, O. Schaum, N. Ludwig, N. Fehlmann, T. Engel, A. Henn, D. Rishik, S. Isakova, A. Tan, M. Sit, R. Neff, N. Hart, M. Meese, E. Quake, S. Wyss-Coray, T. Keller, A.

Characterizing expression changes in noncoding RNAs during aging and heterochronic parabiosis across mouse tissues
, 1087-0156 (2023)
Bublitz, A. Brauer, M. Wagner, S. Hofer, W. Müsken, M. Deschner, F. Lesker, T.R. Neumann-Schaal, M. Paul, L. Nübel, U. Bartel, J. Kany, A.M. Zühlke, D. Bernecker, S. Jansen, R. Sievers, S. Riedel, K. Herrmann, J. Müller, R. Fuchs, T.M. Strowig, T.

The natural product chlorotonil A preserves colonization resistance and prevents relapsing Clostridioides difficile infection
, 1931-3128 (2023)
Collias, D. Vialetto, E. Yu, J. Co, K. Almási, È. Rüttiger, A.S. Achmedov, T. Strowig, T. Beisel, C.L.

Systematically attenuating DNA targeting enables CRISPR-driven editing in bacteria
, 20411723 (ISSN) (2023)
Carius, P. Jungmann, A. Bechtel, M. Grißmer, A. Boese, A. Gasparoni, G. Salhab, A. Seipelt, R. Urbschat, K. Richter, C. Meier, C. Bojkova, D. Cinatl, J. Walter, J. Schneider-Daum, N. Lehr, C.M.

A Monoclonal Human Alveolar Epithelial Cell Line ("Arlo") with Pronounced Barrier Function for Studying Drug Permeability and Viral Infections
, 21983844 (ISSN) (2023)
Leipold, A.M. Werner, R.A. Düll, J. Jung, P. John, M. Stanojkovska, E. Zhou, X. Hornburger, H. Ruckdeschel, A. Dietrich, O. Imdahl, F. Krammer, T. Knop, S. Rosenwald, A. Buck, A. Sander, L.E. Einsele, H. Kortüm, K.M. Saliba, A.E. Rasche, L.

Th17.1 cell driven sarcoidosis-like inflammation after anti-BCMA CAR T cells in multiple myeloma
, 08876924 (ISSN) (2023)
Koller, T.O. Scheid, U. Kösel, T. Herrmann, J. Krug, D. Boshoff, H.I.M. Beckert, B. Evans, J.C. Schlemmer, J. Sloan, B. Weiner, D.M. Via, L.E. Moosa, A. Ioerger, T.R. Graf, M. Zinshteyn, B. Abdelshahid, M. Nguyen, F. Arenz, S. Gille, F. Siebke, M. Se [...]

The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition
, 00027863 (ISSN) (2023)
Dmytrenko, O. Neumann, G.C. Hallmark, T. Keiser, D.J. Crowley, V.M. Vialetto, E. Mougiakos, I. Wandera, K.G. Domgaard, H. Weber, J. Gaudin, T. Metcalf, J. Gray, B.N. Begemann, M.B. Jackson, R.N. Beisel, C.L.

Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA
, 00280836 (ISSN) (2023)
Hamed, M.M. Abdelsamie, A.S. Rox, K. Schütz, C. Kany, A.M. Röhrig, T. Schmelz, S. Blankenfeldt, W. Arce-Rodriguez, A. Borrero-de Acuna, J.M. Jahn, D. Rademacher, J. Ringshausen, F.C. Cramer, N. T++mmler, B. Hirsch, A.K.H. Hartmann, R.W. Empting, M.

Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle
, 21983844 (ISSN) (2023)
Keller, L. Oueis, E. Kaur, A. Safaei, N. Kirsch, S.H. Gunesch, A.P. Haid, S. Rand, U. Cicin-Sain, L. Fu, C. Wink, J. Pietschmann, T. Müller, R.

Persicamidines - Unprecedented Sesquarterpenoids with Potent Antiviral Bioactivity against Coronaviruses
, 1433-7851 (2022)

Donations

The Strategy of the HZI

Research report 2020/2021

Working at the HZI

The HZI in social networks

Feature: Coronaviruses

SARS-CoV-2 / COVID-19

InFact - the HZI magazine

Story

COVID-19 Vaccine

Pandemic preparation

Donation

Research

Locations

Jobs

Selected Publications

Characterizing expression changes in noncoding RNAs during aging and heterochronic parabiosis across mouse tissues

The natural product chlorotonil A preserves colonization resistance and prevents relapsing Clostridioides difficile infection

Systematically attenuating DNA targeting enables CRISPR-driven editing in bacteria

A Monoclonal Human Alveolar Epithelial Cell Line ("Arlo") with Pronounced Barrier Function for Studying Drug Permeability and Viral Infections

Th17.1 cell driven sarcoidosis-like inflammation after anti-BCMA CAR T cells in multiple myeloma

The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition

Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA

Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle

Persicamidines - Unprecedented Sesquarterpenoids with Potent Antiviral Bioactivity against Coronaviruses