Prof. Dr. Luka Cicin-Sain

Krstanovic F., Mihalic A., Rashidi A.S., Sitnik K.M., Ruzsics Z., Cicin-Sain L., Verjans G.M.G.M., ... , Jonjic S., Brizic I. (2025)

Neuron-restricted cytomegalovirus latency in the central nervous system regulated by CD4(+) T-cells and IFN-y

J.Neuroinflammation., 22 (1)

DOI: 10.1186/s12974-025-03422-6 HZI-Repositorium PubMed

van der Sluis R.M., Garcia-Rodriguez J.L., Nielsen I.H., Gris-Oliver A., Becker J., Costa B., Chaudhry M.Z., Werner M., Laustsen A., Pedersen J.G., Gammelgaard K.R., Mogensen T.H., Kalinke U., Cicin-Sain L., Bak R.O., ... , Kristensen L.S., Jakobsen M.R. (2025)

Distinctive CD8+ T cell activation by antigen-presenting plasmacytoid dendritic cells compared to conventional dendritic cells

Cell Rep., 44 (3)

DOI: 10.1016/j.celrep.2025.115413 HZI-Repositorium PubMed

Hundhausen N., Majumder S., Xiao Y., Haeusl S.S., Goehler H., Seal R., Chiarolla C.M., Rosenwald A., Eyrich M., ... , Cicin-Sain L., Berberich-Siebelt F. (2025)

NFAT single-deficient murine T cells reduce the risk of aGvHD while controlling cytomegalovirus infection

iScience, 28 (2)

DOI: 10.1016/j.isci.2025.111937 HZI-Repositorium PubMed

Bdeir N., Lüddecke T., Maaß H., Schmelz S., Rand U., Jacobsen H., Metzdorf K., Kulkarni U., Cossmann A., Stankov M.V., Hoffmann M., Pöhlmann S., Blankenfeldt W., Dopfer-Jablonka A., ... , Behrens G.M.N., Cicin-Sain L. (2025)

Reverse mutational scanning of SARS-CoV-2 spike BA.2.86 identifies epitopes contributing to immune escape from polyclonal sera

Nat Commun, 16 (1)

DOI: 10.1038/s41467-025-55871-5 HZI-Repositorium PubMed

Yu Z., Sasidharan-Nair V., Buchta T., Bonifacius A., Khan F., Pietzsch B., Ahmadi H., Beckstette M., Niemz J., Hilgendorf P., Mausberg P., Keller A., Falk C., Busch D.H., Schober K., Cicin-Sain L., Müller F., Brinkmann M.M., Eiz-Vesper B., ... , Floess S., Huehn J. (2024)

DNA methylation profiling identifies TBKBP1 as potent amplifier of cytotoxic activity in CMV-specific human CD8+ T cells

PLoS.Pathog., 20 (9)

DOI: 10.1371/journal.ppat.1012581 HZI-Repositorium PubMed

Innocenti G., Obara M., Costa B., Jacobsen H., Katzmarzyk M., Cicin-Sain L., ... , Kalinke U., Galardini M. (2024)

Real-time identification of epistatic interactions in SARS-CoV-2 from large genome collections

Genome Biology, 25 (1)

DOI: 10.1186/s13059-024-03355-y HZI-Repositorium PubMed

Khan F., Müller T.R., Kasmapour B., Ynga-Durand M.A., Eiz-Vesper B., Von Einem J., ... , Busch D.H., Cicin-Sain L. (2024)

Dynamic monitoring of viral gene expression reveals rapid antiviral effects of CD8 T cells recognizing the HCMV-pp65 antigen

Frontiers in Immunology, 15

DOI: 10.3389/fimmu.2024.1439184 HZI-Repositorium PubMed

Metzdorf K., Jacobsen H., Kim Y., Teixeira Alves L.G., Kulkarni U., Brdovcak M.C., Materljan J., Eschke K., Chaudhry M.Z., Hoffmann M., Bertoglio F., Ruschig M., Hust M., Sustic M., Krmpotic A., Jonjic S., Widera M., Ciesek S., Pöhlmann S., ... , Landthaler M., Cicin-Sain L. (2024)

A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants

Frontiers in Immunology, 15

DOI: 10.3389/fimmu.2024.1383086 HZI-Repositorium PubMed

Winterhalter P.M., Warmuth L., Hilgendorf P., Schütz J.M., Dötsch S., Tonn T., Cicin-Sain L., ... , Busch D.H., Schober K. (2024)

HLA reduction of human T cells facilitates generation of immunologically multicompatible cellular products

Blood Advances, 8 (13)

DOI: 10.1182/bloodadvances.2023011496 PubMed

Santamorena M.M., Tischer-Zimmermann S., Bonifacius A., Mireisz C.N.-M., Costa B., Khan F., Kulkarni U., Lauruschkat C.D., Sampaio K.L., Stripecke R., Blasczyk R., Maecker-Kolhoff B., Kraus S., Schlosser A., Cicin-Sain L., ... , Kalinke U., Eiz-Vesper B. (2024)

Engineered HCMV-infected APCs enable the identification of new immunodominant HLA-restricted epitopes of anti-HCMV T-cell immunity

HLA, 103 (6)

DOI: 10.1111/tan.15541 HZI-Repositorium PubMed

Maaß H., Ynga-Durand M., Milosevic M., Krstanovic F., Matesic M.P., Zuza I., Jonjic S., Brizic I., Sustic A., Bloos F., SepNet Critical Care Trials Group, ... , Protic A., Cicin-Sain L. (2024)

Serum cytokine dysregulation signatures associated with COVID-19 outcomes in high mortality intensive care unit cohorts across pandemic waves and variants

Sci.Rep., 14 (1)

DOI: 10.1038/s41598-024-64384-y HZI-Repositorium PubMed

Becker B., Wottawa F., Bakr M., Koncina E., Mayr L., Kugler J., Yang G., Windross S.J., Neises L., Mishra N., Harris D., Tran F., Welz L., Schwärzler J., Banki Z., Stengel S.T., Ito G., Krötz C., Coleman O.I., Jaeger C., Haller D., Paludan S.R., Blumberg R., Kaser A., Cicin-Sain L., Schreiber S., Adolph T.E., Letellier E., Rosenstiel P., ... , Meiser J., Aden K. (2024)

Serine metabolism is crucial for cGAS-STING signaling and viral defense control in the gut

iScience, 27 (3)

DOI: 10.1016/j.isci.2024.109173 HZI-Repositorium PubMed

Chaudhry M.Z., Borkner L., Kulkarni U., Berberich-Siebelt F., Cicin-Sain L. (2024)

NFAT signaling is indispensable for persistent memory responses of MCMV-specific CD8+ T cells

PLoS Pathogens, 20 (2 / February)

DOI: 10.1371/journal.ppat.1012025 HZI-Repositorium PubMed

Costa B., Becker J., Krammer T., Mulenge F., Duran V., Pavlou A., Gern O.L., Chu X., Li Y., Cicin-Sain L., Eiz-Vesper B., Messerle M., Dölken L., Saliba A.E., ... , Erhard F., Kalinke U. (2024)

Human cytomegalovirus exploits STING signaling and counteracts IFN/ISG induction to facilitate infection of dendritic cells

Nat.Commun., 15 (1)

DOI: 10.1038/s41467-024-45614-3 HZI-Repositorium PubMed

Alfi O., Cohen M., Bar-On S., Hashimshony T., Levitt L., Raz Y., Blecher Y., Chaudhry M.Z., Cicin-Sain L., Ben-El R., Oiknine-Djian E., Lahav T., Vorontsov O., Cohen A., Zakay-Rones Z., Daniel L., Berger M., Mandel-Gutfreund Y., ... , Panet A., Wolf D.G. (2024)

Decidual-tissue-resident memory T cells protect against nonprimary human cytomegalovirus infection at the maternal-fetal interface

Cell Rep., 43 (2)

DOI: 10.1016/j.celrep.2024.113698 HZI-Repositorium PubMed

Zhang L., Kempf A., Nehlmeier I., Cossmann A., Richter A., Bdeir N., Graichen L., Moldenhauer A.S., Dopfer-Jablonka A., Stankov M.V., Simon-Loriere E., Schulz S.R., Jäck H.M., Cicin-Sain L., Behrens G.M.N., Drosten C., ... , Hoffmann M., Pöhlmann S. (2024)

SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency

Cell, 187 (3)

DOI: 10.1016/j.cell.2023.12.025 HZI-Repositorium PubMed

Cicin-Sain L. (2023)

Effects and safety profile of childhood vaccines in the light of the biological basis of the immune response

Lijec.Vjesn., 145

DOI: 10.26800/LV-145-supl5-2 HZI-Repositorium

Katzmarzyk M., Clesle D.C., van den Heuvel J., Hoffmann M., Garritsen H., Pöhlmann S., ... , Jacobsen H., Cicin-Sain L. (2023)

Systematical assessment of the impact of single spike mutations of SARS-CoV-2 Omicron sub-variants on the neutralization capacity of post-vaccination sera

Front.Immunol., 14

DOI: 10.3389/fimmu.2023.1288794 HZI-Repositorium PubMed

Abassi L., Bertoglio F., Macak Safranko Z, Schirrmann T., Greweling-Pils M., Seifert O., Khan F., Katzmarzyk M., Jacobsen H., Gödecke N., Heine P.A., Frenzel A., Nowack H., Dübel S., Kurolt I.C., Kontermann R.E., Markotic A., Schubert M., ... , Hust M., Cicin-Sain L. (2023)

Evaluation of the Neutralizing Antibody STE90-C11 against SARS-CoV-2 Delta Infection and Its Recognition of Other Variants of Concerns

Viruses, 15 (11)

DOI: 10.3390/v15112153 HZI-Repositorium PubMed

Jiang B., Schmitt M.J., Rand U., Company C., Dramaretska Y., Grossmann M., Serresi M., ... , Cicin-Sain L., Gargiulo G. (2023)

Pharmacological modulators of epithelial immunity uncovered by synthetic genetic tracing of SARS-CoV-2 infection responses

Sci.Adv., 9 (25)

DOI: 10.1126/sciadv.adf4975 HZI-Repositorium PubMed

Sitnik K.M., Krstanovic F., Gödecke N., Rand U., Kubsch T., Maaß H., Kim Y., ... , Brizic I., Cicin-Sain L. (2023)

Fibroblasts are a site of murine cytomegalovirus lytic replication and Stat1-dependent latent persistence in vivo

Nat.Commun., 14 (1)

DOI: 10.1038/s41467-023-38449-x HZI-Repositorium PubMed

Metzdorf K., Jacobsen H., Greweling-Pils M.C., Hoffmann M., Lüddecke T., Miller F., Melcher L., Kempf A.M., Nehlmeier I., Bruder D., Widera M., Ciesek S., ... , Pöhlmann S., Cicin-Sain L. (2023)

TMPRSS2 Is Essential for SARS-CoV-2 Beta and Omicron Infection

Viruses, 15 (2)

DOI: 10.3390/v15020271 HZI-Repositorium PubMed

Dötsch S., Svec M., Schober K., Hammel M., Wanisch A., Gökmen F., Jarosch S., Warmuth L., Barton J., Cicin-Sain L., ... , D'Ippolito E., Busch D.H. (2023)

Long-term persistence and functionality of adoptively transferred antigen-specific T cells with genetically ablated PD-1 expression

Proc.Natl.Acad.Sci.U.S.A., 120 (10)

DOI: 10.1073/pnas.2200626120

Schwerk J., Kemper L., Bussey K.A., Lienenklaus S., Weiss S., Cicin-Sain L., Kröger A., Kalinke U., Collins C.M., Speck S.H., Messerle M., Wirth D., Brinkmann M.M., ... , Hauser H., Köster M. (2022)

Type I Interferon Signaling Controls Gammaherpesvirus Latency In Vivo

Pathogens, 11 (12)

DOI: 10.3390/pathogens11121554 HZI-Repositorium PubMed

Keller L., Oueis E., Kaur A., Safaei N., Kirsch S.H., Gunesch A.P., Haid S., Rand U., Cicin-Sain L., Fu C., Wink J., ... , Pietschmann T., Müller R. (2022)

Persicamidines - Unprecedented Sesquarterpenoids with Potent Antiviral Bioactivity against Coronaviruses

Angew.Chem.Int.Ed Engl.

DOI: 10.1002/anie.202214595 HZI-Repositorium PubMed

Jacobsen H., Strengert M., Maaß H., Ynga Durand M.A., Katzmarzyk M., Kessel B., Harries M., Rand U., Abassi L., Kim Y., Lüddecke T., Metzdorf K., Hernández P., Ortmann J., Heise J.K., Castell S., Gornyk D., Glöckner S., Melhorn V., Kemmling Y., Lange B., Dulovic A., Marsall P., Häring J., Junker D., Schneiderhan-Marra N., Hoffmann M., Pöhlmann S., ... , Krause G., Cicin-Sain L. (2022)

Diminished neutralization responses towards SARS-CoV-2 Omicron VoC after mRNA or vector-based COVID-19 vaccinations

Sci.Rep., 12 (1)

DOI: 10.1038/s41598-022-22552-y HZI-Repositorium PubMed

Brlic P.K., Pavletic M., Lerga M., Krstanovic.F., Matesic M.P., Miklic K., Malic S., Miksa L., Pajcur M., Peruc D., Schubert M., Bertoglio F., Arapovic J., Protic A., Sustic A, Milosevic M, Cicin-Sain L., Jonjic S., ... , Lisnic V., Brizic I. (2022)

SARS-CoV-2 Spike and Nucleocapsid Antibody Response in Vaccinated Croatian Healthcare Workers and Infected Hospitalized Patients: A Single Center Cohort Study

Viruses, 14 (9)

DOI: 10.3390/v14091966 HZI-Repositorium PubMed

Jacobsen H., Cobos Jiménez, Sitaras I., Bar-Zeev N., Cicin-Sain L., ... , Higdon M.M., Deloria-Knoll M. (2022)

Post-vaccination T cell immunity to omicron

Front.Immunol., 13

DOI: 10.3389/fimmu.2022.944713 HZI-Repositorium PubMed

Pardieck I.N., van der Sluis T.C., van der Gracht E.T.I., Veerkamp D.M.B., Behr F.M., van Duikeren S., Beyrend G., Rip J., Nadafi R., Beyranvand Nejad E., Mülling N., Brasem D.J., Camps M.G.M., Myeni S.K., Bredenbeek P.J., Kikkert M., Kim Y., Cicin-Sain L., Abdelaal T., van Gisbergen K.P.J.M., Franken K.L.M.C., Drijfhout J.W., Melief C.J.M., Zondag G.C.M., ... , Ossendorp F., Arens R. (2022)

A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection

Nat.Commun., 13 (1)

DOI: 10.1038/s41467-022-31721-6 HZI-Repositorium PubMed

Ynga-Durand M., Maaß H., Milosevic M., Krstanovic F., Pribanic Matesic M., Jonjic S., Protic A., Brizic I., ... , Sustic A., Cícín-Saín L. (2022)

SARS-CoV-2 Viral Load in the Pulmonary Compartment of Critically Ill COVID-19 Patients Correlates with Viral Serum Load and Fatal Outcomes

Viruses., 14 (6)

DOI: 10.3390/v14061292 HZI-Repositorium PubMed

Ballmann R., Hotop S.K., Bertoglio F., Steinke S., Heine P.A., Chaudhry M.Z., Jahn D., Pucker B., Baldanti F., Piralla A., Schubert M., Cícín-Saín L., Brönstrup M., ... , Hust M., Dübel S. (2022)

ORFeome Phage Display Reveals a Major Immunogenic Epitope on the S2 Subdomain of SARS-CoV-2 Spike Protein

Viruses., 14 (6)

DOI: 10.3390/v14061326 HZI-Repositorium PubMed

Khorenko M., Rand U., Cicin-Sain L., Feldmann C. (2022)

Foscarnet-Type Inorganic-Organic Hybrid Nanoparticles for Effective Antiviral Therapy

ACS Biomater.Sci Eng, 8 (4)

DOI: 10.1021/acsbiomaterials.2c00074 HZI-Repositorium PubMed

Hotop S.K., Reimering S., Shekhar A., Asgari E., Beutling U., Dahlke C., Fathi A., Khan F., Lütgehetmann M., Ballmann R., Gerstner A., Tegge W., Cicin-Sain L., Bilitewski U., ... , McHardy A.C., Brönstrup M. (2022)

Peptide microarrays coupled to machine learning reveal individual epitopes from human antibody responses with neutralizing capabilities against SARS-CoV-2

Emerg.Microbes Infect, 11 (1)

DOI: 10.1080/22221751.2022.2057874 HZI-Repositorium PubMed

Cokaric Brdovcak M., Materljan J., Sustic M., Ravlic S., Ruzic T., Lisnic B., Miklic K., Brizic I., Matesic M.P., Lisnic V.J., Halassy B., Roncevic D., Knezevic Z., Stefan L., Bertoglio F., Schubert M., Cicin-Sain L., Markotic A., ... , Jonjic S., Krmpotic A. (2022)

ChAdOx1-S adenoviral vector vaccine applied intranasally elicits superior mucosal immunity compared to the intramuscular route of vaccination

Eur J Immunol

DOI: 10.1002/eji.202249823 HZI-Repositorium PubMed

Schubert M., Bertoglio F., Steinke S., Heine P.A., Ynga-Durand M.A., Maass H., Sammartino J.C., Cassaniti I., Zuo F., Du L., Korn J., Milosevic M., Wenzel E.V., Krstanovic F., Polten S., Pribanic-Matesic M., Brizic I., Baldanti F., Hammarström L., Dübel S., Sustic A, Marcotte H., Strengert M., Protic A., Piralla A., Pan-Hammarström Q., ... , Cicin-Sain L., Hust M. (2022)

Human serum from SARS-CoV-2-vaccinated and COVID-19 patients shows reduced binding to the RBD of SARS-CoV-2 Omicron variant

BMC Med., 20 (1)

DOI: 10.1186/s12916-022-02312-5 HZI-Repositorium PubMed

Wöhrle F., Kerscher B., Cicin-Sain L., Bekeredjian-Ding I. (2022)

DGfI Study Group Vaccines - Annual Meeting 2022

Eur.J.Immunol., 52 (3)

DOI: 10.1002/eji.202270035 HZI-Repositorium PubMed

Baliu-Piqué M., Drylewicz J., Zheng X., Borkner L., Swain A.C., Otto S.A., de Boer R.J., Tesselaar K., ... , Cicin-Sain L., Borghans J.A.M. (2022)

Turnover of Murine Cytomegalovirus-Expanded CD8(+) T Cells Is Similar to That of Memory Phenotype T Cells and Independent of the Magnitude of the Response

J.Immunol., 208 (4)

DOI: 10.4049/jimmunol.2100883 HZI-Repositorium PubMed

Kim Y., Zheng X., Eschke K., Chaudhry M.Z., Bertoglio F., Tomic A., Krmpotic A., Hoffmann M., Bar-On Y., Boehme J., Bruder D., Ebensen T., Brunotte L., Ludwig S., Messerle M., Guzmán C., Mandelboim O., Hust M., Pöhlmann S., ... , Jonjic S., Cicin-Sain L. (2022)

MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination

Cell Mol.Immunol., 19 (2)

DOI: 10.1038/s41423-021-00814-5 HZI-Repositorium PubMed

Chaudhry M.Z., Eschke K., Hoffmann M., Grashoff M., Abassi L., Kim Y., Brunotte L., Ludwig S., Kröger A., Klawonn F., ... , Pöhlmann S.H., Cicin-Sain L. (2022)

Rapid SARS-CoV-2 Adaptation to Available Cellular Proteases

J.Virol.

DOI: 10.1128/jvi.02186-21 HZI-Repositorium PubMed

Cossarizza A., Chang H.D., Radbruch A., Abrignani S., Addo R., Akdis M., Andrä I., Andreata F., Annunziato F., Arranz E., Bacher P., Bari S., Barnaba V., Barros-Martins J., Baumjohann D., Beccaria C.G., Bernardo D., Boardman D.A., Borger J., Böttcher C., Brockmann L., Burns M., Busch D.H., Cameron G., Cammarata I., Cassotta A., Chang Y., Chirdo F.G., Christakou E., Cicin-Sain L., Cook L., Corbett A.J., Cornelis R., Cosmi L., Davey M.S., De Biasi S., De Simone G., Del Zotto G., Delacher M., Di Rosa F., Santo J.D., Diefenbach A., Dong J., Dörner T., Dress R.J., Dutertre C.A., Eckle S.B.G., Eede P., Evrard M., Falk C.S., Feuerer M., Fillatreau S., Fiz-Lopez A., Follo M., Foulds G.A., Fröbel J., Gagliani N., Galletti G., Gangaev A., Garbi N., Garrote J.A., Geginat J., Gherardin N.A., Gibellini L., Ginhoux F., Godfrey D.I., Gruarin P., Haftmann C., Hansmann L., Harpur C.M., Hayday A.C., Heine G., Hernandez D.C., Herrmann M., Hoelsken O., Huang Q., Huber S., Huber J.E., Hühn J., Hundemer M., Hwang W.Y.K., Iannacone M., Ivison S.M., Jäck H.M., Jani P.K., Keller B., Kessler N., Ketelaars S., Knop L., Knopf J., Koay H.F., Kobow K., Kriegsmann K., Kristyanto H., Krueger A., Kuehne J.F., Kunze-Schumacher H., Kvistborg P., Kwok I., Latorre D., Lenz D., Levings M.K., Lino A.C., Liotta F., Long H.M., Lugli E., MacDonald K.N., Maggi L., Maini M.K., Mair F., Manta C., Manz R.A., Mashreghi M.F., Mazzoni A., McCluskey J., Mei H.E., Melchers F., Melzer S., Mielenz D., Monin L., Moretta L., Multhoff G., Munoz L.E., Munoz-Ruiz M., Muscate F., Natalini A., Neumann K., Ng L.G., Niedobitek A., Niemz J., Almeida L.N., Notarbartolo S., Ostendorf L., Pallett L.J., Patel A.A., Percin G.I., Peruzzi G., Pinti M., Pockley A.G., Pracht K., Prinz I., Pujol-Autonell I., Pulvirenti N., Quatrini L., Quinn K.M., Radbruch H., Rhys H., Rodrigo M.B., Romagnani C., Saggau C., Sakaguchi S., Sallusto F., Sanderink L., Sandrock I., Schauer C., Scheffold A., Scherer H.U., Schiemann M., Schildberg F.A., Schober K., Schoen J., Schuh W., ler T., Schulz A.R., Schulz S., Schulze J., Simonetti S., Singh J., Sitnik K.M., Stark R., Starossom S., Stehle C., Szelinski F., Tan L., Tarnok A., Tornack J., Tree T.I.M., van Beek J.J.P., van de Veen W., van Gisbergen K., Vasco C., Verheyden N.A., von Borstel A., Ward-Hartstonge K.A., Warnatz K., Waskow C., Wiedemann A., Wilharm A., Wing J., Wirz O., Wittner J., ... , Yang J.H.M., Yang J. (2021)

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

Eur.J.Immunol., 51 (12)

DOI: 10.1002/eji.202170126 HZI-Repositorium PubMed

Pezoldt J., Wiechers C., Erhard F., Rand U., Bulat T., Beckstette M., Brendolan A., Hühn J., Kalinke U., Mueller M., Strobl B., Deplancke B., ... , Cicin-Sain L., Sitnik K.M. (2021)

Single-cell transcriptional profiling of splenic fibroblasts reveals subset-specific innate immune signatures in homeostasis and during viral infection

Commun.Biolog., 4 (1)

DOI: 10.1038/s42003-021-02882-9 HZI-Repositorium PubMed

Zimmer M.M., Kibe A., Rand U., Pekarek L., Ye L., Buck S., Smyth R.P., ... , Cicin-Sain L., Caliskan N. (2021)

The short isoform of the host antiviral protein ZAP acts as an inhibitor of SARS-CoV-2 programmed ribosomal frameshifting

Nat.Commun., 12 (1)

DOI: 10.1038/s41467-021-27431-0 HZI-Repositorium PubMed

Olbrich L., Stockdale L., Basu Roy R., Song R., Cicin-Sain L., Whittaker E., Prendergast A.J., ... , Fletcher H., Seddon J.A. (2021)

Understanding the interaction between cytomegalovirus and tuberculosis in children: The way forward

PLoS.Pathog., 17 (12)

DOI: 10.1371/journal.ppat.1010061 HZI-Repositorium PubMed

Flommersfeld S., Böttcher J.P., Ersching J., Flossdorf M., Meiser P., Pachmayr L.O., Leube J., Hensel I., Jarosch S., Zhang Q., Chaudhry M.Z., Andrae I., Schiemann M., Busch D.H., Cicin-Sain L., Sun J.C., Gasteiger G., Victora G.D., Höfer T., ... , Buchholz V.R., Grassmann S. (2021)

Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection

Immunity.

DOI: 10.1016/j.immuni.2021.08.002 HZI-Repositorium PubMed

Müller T.R., Jarosch S., Hammel M., Leube J., Grassmann S., Bernard B., Effenberger M., Andrä I., Chaudhry M.Z., Käuferle T., Malo A., Cicin-Sain L., Steinberger P., Feuchtinger T., Protzer U., Schumann K., Neuenhahn M., ... , Schober K., Busch D.H. (2021)

Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy

Cell Rep.Med., 2 (8)

DOI: 10.1016/j.xcrm.2021.100374 HZI-Repositorium PubMed

Rand U., Kupke S.Y., Shkarlet H., Hein M.D., Hirsch T., Marichal-Gallardo P., Cicin-Sain L., ... , Reichl U., Bruder D. (2021)

Antiviral Activity of Influenza A Virus Defective Interfering Particles against SARS-CoV-2 Replication In Vitro through Stimulation of Innate Immunity

Cells, 10 (7)

DOI: 10.3390/cells10071756 HZI-Repositorium PubMed

Bertoglio F., Fühner V., Ruschig M., Heine P.A., Abassi L., Klünemann T., Rand U., Meier D., Langreder N., Steinke S., Ballmann R., Schneider K., Roth K.D.R., Kuhn P., Riese P., Schäckermann D., Korn J., Koch A., Chaudhry M.Z., Eschke K., Kim Y., Zock-Emmenthal S., Becker M., Scholz M., Moreira G.M.S.G., Wenzel E.V., Russo G., Garritsen H.S.P., Casu S., Gerstner A., Roth G., Adler J., Trimpert J., Hermann A., Schirrmann T., Dübel Stefan, Frenzel A., van den Heuvel J., Cicin-Sain L., ... , Schubert M., Hust M. (2021)

A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations

Cell Rep., 36 (4)

DOI: 10.1016/j.celrep.2021 HZI-Repositorium PubMed

Pommerenke C., Rand U., Uphoff C.C., Nagel S., Zaborski M., Hauer V., Kaufmann M., Meyer C., Denkmann S.A., Riese P., Eschke K., Kim Y., Safranko Z.M., Kurolt I.C., Markotic A., ... , Cicin-Sain L., Steenpass L. (2021)

Identification of cell lines CL-14, CL-40 and CAL-51 as suitable models for SARS-CoV-2 infection studies

PLoS ONE, 16 (8)

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Cicin-Sain L., Smyk-Pearson S., Currier N., Byrd L., Koudelka C., Robinson T., Swarbrick G., Tackitt S., Legasse A., Fischer M., Nikolich-Zugich D., Park B., Hobbs T., Doane C.J., Mori M., Axthelm M.K., ... , Lewinsohn D.A., Nikolich-Zugich J. (2010)

Loss of naive T cells and repertoire constriction predict poor response to vaccination in old primates

Journal of Immunology, 184 (12)

Prof. Dr. Dr. Luka Cicin-Sain

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