PD Dr. Frank Pessler

PD Dr. Frank Pessler
Forschungsgruppenleiter

PD Dr. Frank Pessler

Publikationen
Sohail A., Waqas F.H., Braubach P., Czichon L., Samir M., Iqbal A., de Araujo L., Pleschka S., Steinert M., ... , Geffers R., Pessler F. (2024)
Differential transcriptomic host responses in the early phase of viral and bacterial infections in human lung tissue explants ex vivo
Respir.Res., 25 (1)

Kumar S., Zoodsma M., Nguyen N., Pedroso R., Trittel S., Riese P., Botey-Bataller J., Zhou L., Alaswad A., Arshad H., Netea M.G., Xu C.J., Pessler F., Guzman C.A., ... , Graca L., Li Y. (2024)
Systemic dysregulation and molecular insights into poor influenza vaccine response in the aging population
Sci.Adv., 10 (39)

Neu F., Nay S., Schuchardt S., Klawonn F., Skripuletz T., ... , Suehs K.W., Pessler F. (2024)
Targeted metabolomics identifies accurate CSF metabolite biomarkers for the differentiation between COVID-19 with neurological involvement and CNS infections with neurotropic viral pathogens
Journal of Translational Medicine, 22 (1)

Waqas F.H., Chen C., Pessler F. (2024)
Aconitate decarboxylase (ACOD1) has found a disease
Trends in Endocrinology and Metabolism, 35 (7)

Al-Mekhlafi A., Waqas F.H., Krueger M., Klawonn F., Akmatov M.K., Müller-Vahl K., Trebst C., Skripuletz T., Stangel M., ... , Sühs K.W., Pessler F. (2023)
Elevated phospholipids and acylcarnitines C4 and C5 in cerebrospinal fluid distinguish viral CNS infections from autoimmune neuroinflammation
J.Transl.Med., 21 (1)

Akmatov M.K., Beisheeva N.J., Nurmatov A.Z., Gulsunai S.J., Saikal K.N., Derkenbaeva A.A., Abdrahmanova Z.O., Prokein J., Klopp N., Illig T., Kasymov O.T., ... , Nurmatov Z.S., Pessler F. (2023)
The Changing Epidemiology of Viral Hepatitis in a Post-Soviet Country-The Case of Kyrgyzstan
Pathogens., 12 (8)

Waqas F.H., Shehata M., Elgaher W.A.M., Lacour A., Kurmasheva N., Begnini F., Kiib A.E., Dahlmann J., Chen C., Pavlou A., Poulsen T.B., Merkert S., Martin U., Olmer R., Olagnier D., Hirsch A.K.H., ... , Pleschka S., Pessler F. (2023)
NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner
PLoS.Pathog., 19 (7)

Chen F., Yalcin I., Zhao M., Chen C., Blankenfeldt W., ... , Pessler F., Büssow K. (2023)
Amino acid positions near the active site determine the reduced activity of human ACOD1 compared to murine ACOD1
Sci.Rep., 13 (1)

Merkert S., Haase A., Dahlmann J., Göhring G., Waqas F.H., Pessler F., ... , Martin U., Olmer R. (2023)
Generation of two human NRF2 knockout iPSC clones using CRISPR/Cas9 editing
Stem Cell Research, 69 (June 2023)

Riese P., Trittel S., Akmatov M.K., May M., Prokein J., Illig T., Schindler C., Sawitzki B., Elfaki Y., Floess S., Huehn J., Blazejewski A.J., Strowig T., Hernandez-Vargas E.A., Geffers R., Zhang B., Li Y., ... , Pessler F., Guzmán C.A. (2022)
Distinct immunological and molecular signatures underpinning influenza vaccine responsiveness in the elderly
Nat.Commun., 13 (1)

Arshad H., Siokis A., Franke R., Habib A., Alfonso J.C.L., Poliakova Y., Lücke E., Michaelis K., Brönstrup M., Meyer-Hermann M., Bilitewski U., Vila J., Abel L., Illig T., ... , Schreiber J., Pessler F. (2022)
Reprogramming of Amino Acid Metabolism Differs between Community-Acquired Pneumonia and Infection-Associated Exacerbation of Chronic Obstructive Pulmonary Disease
Cells, 11 (15)

Waqas S.F., Sohail A., Nguyen A.H.H., Usman A., Ludwig T., Wegner A., Malik M.N.H., Schuchardt S., Geffers R., Winterhoff M., Merkert S., Martin U., Olmer R., ... , Lachmann N., Pessler F. (2022)
ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives
Clin.Transl.Med., 12 (7)

Gruenwald M., Chen F., Bähre H., Pessler F. (2022)
Itaconate Isomers in Bread
Antioxidants.(Basel), 11 (7)

Chen F., Elgaher W.A.M., Winterhoff M., Büssow K., Waqas F.H., Graner E., Pires-Afonso Y., Casares Perez L., La Vega L., Sahini N., Czichon L., Zobl W., Zillinger T., Shehata M., Pleschka S., Bähre H., Falk C., Michelucci A., Schuchardt S., Blankenfeldt W., ... , Hirsch A.K.H., Pessler F. (2022)
Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism
Nat.Metab, 4 (5)

Sohail A., Iqbal A.A., Sahini N., Chen F., Tantawy M., Waqas F., Winterhoff M., Ebensen T., Schultz K., Geffers R., Schughart K., Preusse M., Shehata M., Bähre H., Pils M.C., Guzmán C.A., Mostafa A., Pleschka S., Falk C., ... , Michelucci A., Pessler F. (2022)
Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection
PLoS Pathog., 18 (1)

Malik M.N.H., Waqas S.F.H., Zeitvogel J., Cheng J., Geffers R., Gouda Z.A., Elsaman A.M., Radwan A.R., Schefzyk M., Braubach P., Auber B., Olmer R., Müsken M., Roesner L.M., Gerold G., Schuchardt S., Merkert S., Martin U., Meissner F., ... , Werfel T., Pessler F. (2021)
Congenital deficiency reveals critical role of ISG15 in skin homeostasis
J.Clin.Invest

de Araujo L.S., Ribeiro-Alves M., Wipperman M.F., Vorkas C.K., Pessler F., Saad M.H.F. (2021)
Transcriptomic biomarkers for tuberculosis: Validation of npc2 as a single mrna biomarker to diagnose tb, predict disease progression, and monitor treatment response
Cells, 10 (10)

Luo Y., Möhn N., Skripuletz T., Senel M., Tumani H., Pessler F., ... , Sühs K.W., Stangel M. (2021)
Differentiation of viral and autoimmune central nervous system inflammation by kynurenine pathway
Ann.Clin.Transl.Neurol.

Ramli S.R., Bunk B., Spröer C., Geffers R., Jarek M., Bhuju S., Goris M., ... , Mustakim S., Pessler F. (2021)
Complete genome sequencing of leptospira interrogans isolates from malaysia reveals massive genome rearrangement but high conservation of virulence-associated genes
Pathogens, 10 (9)

Al-Mekhlafi A., Sühs K.W., Schuchardt S., Kuhn M., Müller-Vahl K., Trebst C., Skripuletz T., Klawonn F., ... , Stangel M., Pessler F. (2021)
Elevated Free Phosphatidylcholine Levels in Cerebrospinal Fluid Distinguish Bacterial from Viral CNS Infections
Cells, 10 (5)

Franz S., Pott F., Zillinger T., Schüler C., Dapa S., Fischer C., Passos V., Stenzel S., Chen F., Döhner K., Hartmann G., Sodeik B., Pessler F., Simmons G., ... , Drexler J.F., Goffinet C. (2021)
Human IFITM3 restricts chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction
Life Sci.Alliance., 4 (7)

Winterhoff M., Chen F., Sahini N., Ebensen T., Kuhn M., Kaever V., ... , Bähre H., Pessler F. (2021)
Establishment, validation, and initial application of a sensitive lc-ms/ms assay for quantification of the naturally occurring isomers itaconate, mesaconate, and citraconate
Metabolites., 11 (5)

Merkert S., Jaboreck M.C., Engels L., Malik M.N.H., Göhring G., Pessler F., ... , Martin U., Olmer R. (2020)
Generation of two human ISG15 knockout iPSC clones using CRISPR/Cas9 editing
Stem Cell Res., 50 (January 2021)

Kreißl S., Hendler S., Akmatov M.K., von Meien M., Range U., ... , Pessler F., Vogelberg C. (2021)
Reduced Exhaled Breath Condensate pH and Severity of Allergic Sensitization Predict School Age Asthma
J.Allergy Clin.Immunol.Pract.

Luo Y., Möhn N., Al-Mekhlafi A., Schuchardt S., Skripuletz T., Sühs W., ... , Pessler F., Stangel M. (2020)
Targeted metabolomic profiling of cerebrospinal fluid from patients with progressive multifocal leukoencephalopathy
PLoS.ONE., 15 (11)

Martin-Fernandez M., Bravo Garcia-Morato M., Gruber C., Murias Loza S., Malik M.N.H., Alsohime F., Alakeel A., Valdez R., Buta S., Buda G., Marti M.A., Larralde M., Boisson B., Feito Rodriguez M., Qiu X., Chrabieh M., Al Ayed M., Al Muhsen S., Desai J.V., Ferre E.M.N., Rosenzweig S.D., Amador-Borrero B., Bravo-Gallego L.Y., Olmer R., Merkert S., Bret M., Sood A.K., Al-Rabiaah A., Temsah M.H., Halwani R., Hernandez M., Pessler F., Casanova J.L., Bustamante J., ... , Lionakis M.S., Bogunovic D. (2020)
Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions
Cell Rep., 31 (6)

Hahn K., Pollmann L., Nowak J., Nguyen A.H.H., Haake K., Neehus A.L., Waqas S.F.H., Pessler F., Baumann U., Hetzel M., Casanova J.L., Schulz A., Bustamante J., ... , Ackermann M., Lachmann N. (2020)
Human Lentiviral Gene Therapy Restores the Cellular Phenotype of Autosomal Recessive Complete IFN-g[gamma]R1 Deficiency
Mol.Ther.Methods Clin.Dev., 17

Freuer D., Linseisen J., Waterboer T., Pessler F., Guzmán C.A., Wawro N., ... , Peters A., Meisinger C. (2020)
Seropositivity of selected chronic infections and different measures of obesity
PLoS.ONE., 15 (4)

Reinke S., Linge M., Diebner H.H., Luksch H., Glage S., Gocht A., Robertson A.A.B., Cooper M.A., Hofmann S.R., Naumann R., Sarov M., Behrendt R., Roers A., Pessler F., Roesler J., ... , Rösen-Wolff A., Winkler S. (2020)
Non-canonical Caspase-1 Signaling Drives RIP2-Dependent and TNF-a[alpha]-Mediated Inflammation In Vivo
Cell Rep., 30 (8)

de Araujo L.S., Pessler K., Suhs K.W., Novoselova N., Klawonn F., Kuhn M., Kaever V., Muller-Vahl K., Trebst C., Skripuletz T., ... , Stangel M., Pessler F. (2020)
Phosphatidylcholine PC ae C44:6 in cerebrospinal fluid is a sensitive biomarker for bacterial meningitis
J.Transl.Med., 18 (1)

de Araujo L.S., Ribeiro-Alves M., Leal-Calvo T., Leung J., Duran V., Samir M., Talbot S., Tallam A., Mello F.C.Q., Geffers R., ... , Saad M.H.F., Pessler F. (2019)
Reprogramming of Small Noncoding RNA Populations in Peripheral Blood Reveals Host Biomarkers for Latent and Active Mycobacterium tuberculosis Infection
MBio., 10 (6)

Arshad H., Alfonso J.C.L., Franke R., Michaelis K., Araujo L., Habib A., Zboromyrska Y., Lucke E., Strungaru E., Akmatov M.K., Hatzikirou H., Meyer-Hermann M., Petersmann A., Nauck M., Brönstrup M., Bilitewski U., Abel L., Sievers J., Vila J., Illig T., ... , Schreiber J., Pessler F. (2019)
Decreased plasma phospholipid concentrations and increased acid sphingomyelinase activity are accurate biomarkers for community-acquired pneumonia
J.Transl.Med., 17 (1)

Samir M., Vidal R.O., Abdallah F., Capece V., Seehusen F., Geffers R., Hussein A., Ali A.A.H., ... , Bonn S., Pessler F. (2020)
Organ-specific small non-coding RNA responses in domestic (Sudani) ducks experimentally infected with highly pathogenic avian influenza virus (H5N1)
RNA.Biol., 17 (1)

Chen F., Lukat P., Iqbal A.A., Saile K., Kaever V., van den Heuvel J., Blankenfeldt W., ... , Büssow K., Pessler F. (2019)
Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis
Proc.Natl.Acad.Sci.U.S.A, 116 (41)

Akmatov M.K., Riese P., Trittel S., May M., Prokein J., Illig T., Schindler C., ... , Guzmán C.A., Pessler F. (2019)
Self-reported diabetes and herpes zoster are associated with a weak humoral response to the seasonal influenza A H1N1 vaccine antigen among the elderly
BMC Infect.Dis., 19 (1)

Wawro N., Aman U., Butt J., Meisinger C., Akmatov M.K., Pessler F., Peters A., Rathmann W., Kääb S., ... , Waterboer T., Linseisen J. (2019)
Helicobacter pylori seropositivity: Prevalence, associations and the impact on incident metabolic diseases/risk factors in the population-based KORA study
Frontiers in Public Health, 7 (Apr.)

Sühs K.W., Novoselova N., Kuhn M., Seegers L., Kaever V., Müller-Vahl K., Trebst C., Skripuletz T., ... , Stangel M., Pessler F. (2019)
Kynurenine is a cerebrospinal fluid biomarker for bacterial and viral CNS infections
J.Infect.Dis., 220 (1)

Ramli S.R., Moreira G.M.S.G., Zantow J., Goris M.G.A., Nguyen V.K., Novoselova N., ... , Pessler F., Hust M. (2019)
Discovery of Leptospira spp. seroreactive peptides using ORFeome phage display
PLoS Negl.Trop.Dis., 13 (1)

Ratuszny D., Sühs K.W., Novoselova N., Kuhn M., Kaever V., Skripuletz T., ... , Pessler F., Stangel M. (2019)
Identification of Cerebrospinal Fluid Metabolites as Biomarkers for Enterovirus Meningitis
Int J Mol Sci, 20 (2)

Chen Y.L., Jing J., Mo Y.Q., Ma J.D., Yang L.J., Chen L.F., Zhang X., Yan T., Zheng D.H., ... , Pessler F., Dai L. (2018)
Presence of hepatitis B virus in synovium and its clinical significance in rheumatoid arthritis
Arthritis Res.Ther., 20 (1)

Strehlitz A., Goldmann O., Pils M.C., Pessler F., Medina E. (2018)
An interferon signature discriminates pneumococcal from staphylococcal pneumonia
Front.Immunol., 9 (JUN)

Olmer R., Engels L., Usman A., Menke S., Malik M.N.H., Pessler F., Göhring G., Bornhorst D., Bolten S., Abdelilah-Seyfried S., Scheper T., Kempf H., ... , Zweigerdt R., Martin U. (2018)
Differentiation of Human Pluripotent Stem Cells into Functional Endothelial Cells in Scalable Suspension Culture
Stem Cell Rep., 10 (5)

Petersen H., Mostafa A., Tantawy M.A., Iqbal A.A., Hoffmann D., Tallam A., Selvakumar B., Pessler F., Beer M., ... , Rautenschlein S., Pleschka S. (2018)
NS segment of a 1918 influenza a virus-descendent enhances replication of H1N1pdm09 and virus-induced cellular immune response in mammalian and avian systems
Front.Microbiol., 9 (MAR)

Loof T.G., Sohail A., Bahgat M.M., Tallam A., Arshad H., Akmatov M.K., Pils M.C., Heise U., ... , Beineke A., Pessler F. (2018)
Early lymphocyte loss and increased granulocyte/lymphocyte ratio predict systemic spread of Streptococcus pyogenes in a mouse model of acute skin infection
Front.Cell.Infect.Microbiol., 8 (APR)

Kuhn M., Sühs K.W., Akmatov M.K., Klawonn F., Wang J., Skripuletz T., Kaever V., ... , Stangel M., Pessler F. (2018)
Mass-spectrometric profiling of cerebrospinal fluid reveals metabolite biomarkers for CNS involvement in varicella zoster virus reactivation
J.Neuroinflammation., 15 (1)

Samir M., Hamed M., Abdallah F., Kinh Nguyen V, Hernandez-Vargas E.A., Seehusen F., Baumgartner W., Hussein A., ... , Ali A.A.H., Pessler F. (2018)
An Egyptian HPAI H5N1 isolate from clade 2.2.1.2 is highly pathogenic in an experimentally infected domestic duck breed (Sudani duck)
Transbound.Emerg.Dis., 65 (3)

Filomena A., Pessler F., Akmatov M.K., Krause G., Duffy D., Gerhard M., ... , Albert M.L., Joos T.O. (2017)
Development of a bead-based multiplex assay for the analysis of the serological response against the six pathogens HAV, HBV, HCV, CMV, T. gondii, and H. pylori
High Throughput, 6 (4)

Krenn V., Perino G., Ruther W., Krenn V.T., Huber M., Hugle T., Najm A., Muller S., Boettner F., Pessler F., Waldstein W., Kriegsmann J., Casadonte R., Haupl T., Wienert S., Krukemeyer M.G., Sesselmann S., Sunitsch S., ... , Tikhilov R., Morawietz L. (2017)
15 years of the histopathological synovitis score, further development and review: A diagnostic score for rheumatology and orthopaedics
Pathol.Res.Pract.

Akmatov M.K., Rober N., Ahrens W., Flesch-Janys D., Fricke J., Greiser H., Gunther K., Kaaks R., Kemmling Y., Krone B., Linseisen J., Meisinger C., Moebus S., Obi N., Guzmán C.A., ... , Conrad K., Pessler F. (2017)
Anti-nuclear autoantibodies in the general German population: prevalence and lack of association with selected cardiovascular and metabolic disorders-findings of a multicenter population-based study
Arthritis Res.Ther., 19 (1)

Pessler F., Sherry D.D. (2011)
Rheumatic Fever
, 20th

Krenn V., Perino G., Ruther W., Krenn V.T., Huber M., Hugle T., Najm A., Muller S., Boettner F., Pessler F., Waldstein W., Kriegsmann J., Haupl T., Wienert S., Krukemeyer M.G., Sesselmann S., ... , Tikhilov R., Morawietz L. (2017)
[Fifteen years of the histopathological synovitis score : Review and further developments of a diagnostic score]
Z.Rheumatol., 76 (6)

Akmatov M.K., Koch N., Vital M., Ahrens W., Flesch-Janys D., Fricke J., Gatzemeier A., Greiser H., Gunther K., Illig T., Kaaks R., Krone B., Kuhn A., Linseisen J., Meisinger C., Michels K., Moebus S., Nieters A., Obi N., Schultze A., Six-Merker J., ... , Pieper D.H., Pessler F. (2017)
Determination of nasal and oropharyngeal microbiomes in a multicenter population-based study - findings from Pretest 1 of the German National Cohort
Sci.Rep., 7 (1)

Preusse M., Schughart K., Wilk E., Klawonn F., Pessler F. (2015)
Hematological parameters in the early phase of influenza A virus infection in differentially susceptible inbred mouse strains Infectious Diseases
BMC Res.Notes, 8 (1)

Schweitzer A., Pessler F., Akmatov M.K. (2016)
Impact of rotavirus vaccination on coverage and timing of pentavalent vaccination - Experience from 2 Latin American countries
Hum.Vaccines Immunother., 12 (5)

Preusse M., Schughart K., Pessler F. (2017)
Host Genetic Background Strongly Affects Pulmonary microRNA Expression before and during Influenza A Virus Infection
Front Immunol., 8

Akmatov M.K., Riese P., May M., Jentsch L., Ahmed M.W., Werner D., Rosel A., Tyler M., Pessler K., Prokein J., Bernemann I., Klopp N., Prochnow B., Trittel S., Tallam A., Illig T., Schindler C., ... , Guzmán C.A., Pessler F. (2017)
Establishment of a cohort for deep phenotyping of the immune response to influenza vaccination among elderly individuals recruited from the general population
Hum.Vaccin.Immunother.

Karabaev B.B., Beisheeva N.J., Satybaldieva A.B., Ismailova A.D., Pessler F., Akmatov M.K. (2017)
Seroprevalence of hepatitis B, hepatitis C, human immunodeficiency virus, Treponema pallidum, and co-infections among blood donors in Kyrgyzstan: a retrospective analysis (2013-2015)
Infect.Dis.Poverty., 6 (1)

Akmatov M.K., Jentsch L., Riese P., May M., Ahmed M.W., Werner D., Rösel A., Prokein J., Bernemann I., Klopp N., Prochnow B., Illig T., Schindler C., ... , Guzmán C.A., Pessler F. (2017)
Motivations for (non)participation in population-based health studies among the elderly - comparison of participants and nonparticipants of a prospective study on influenza vaccination
BMC Med.Res.Methodol., 17 (1)

Samir M., Vaas L.A., Pessler F. (2016)
MicroRNAs in the Host Response to Viral Infections of Veterinary Importance
Front Vet.Sci, 3 (Oct)

de Araujo L.S., Vaas L.A., Ribeiro-Alves M., Geffers R., Mello F.C., de Almeida A.S., Moreira A.D., Kritski A.L., Lapa E Silva JR, Moraes M.O., ... , Pessler F., Saad M.H. (2016)
Transcriptomic Biomarkers for Tuberculosis: Evaluation of DOCK9. EPHA4, and NPC2 mRNA Expression in Peripheral Blood
Front Microbiol., 7 (Oct)

Hendel N., Akmatov M.K., Hamel J., Vogelberg C., Pessler F. (2016)
Exhaled breath analysis in childhood rheumatic disorders - A longitudinal study
J.Breath Res., 10 (2)

Akmatov M.K., Stumme M., Pessler F. (2016)
Real-life practice of methotrexate toxicity monitoring in juvenile idiopathic arthritis in Germany, Switzerland and Austria: results of a cross-sectional assessment conducted in 2012
Clin.Exp.Rheumatol., 34 (3)

Samir M., Pessler F. (2016)
Small Non-coding RNAs Associated with Viral Infectious Diseases of Veterinary Importance: Potential Clinical Applications
Front Vet.Sci, 3

Elsaman A.M., Muhammad E.M., Pessler F. (2016)
Sonographic Findings in Gouty Arthritis: Diagnostic Value and Association with Disease Duration
Ultrasound Med.Biol., 42 (6)

Schlett C.L., Hendel T., Hirsch J., Weckbach S., Caspers S., Schulz-Menger J., Ittermann T., von Knobelsdorff-Brenkenhoff F., Ladd S.C., Moebus S., Stroszczynski C., Fischer B., Leitzmann M., Kuhl C., Pessler F., Hartung D., Kemmling Y., Hetterich H., Amunts K., Gunther M., Wacker F., Rummeny E., Kauczor H.U., Forsting M., Völzke H., Hosten N., ... , Reiser M.F., Bamberg F. (2015)
Quantitative, Organ-Specific Interscanner and Intrascanner Variability for 3 T Whole-Body Magnetic Resonance Imaging in a Multicenter, Multivendor Study
Invest Radiol., 51 (4)

Akmatov M.K., Rubsamen N., Schultze A., Kemmling Y., Obi N., Günther K., Ahrens W., Pessler F., ... , Krause G., Mikolajczyk R.T. (2015)
Diverse recruitment strategies result in different participation percentages in a web-based study, but in similar compliance
Int.J Public Health, 60 (8)

Schweitzer A., Akmatov M.K., Kindler F., Kemmling Y., Kreienbrock L., ... , Krause G., Pessler F. (2015)
The impact of distance and duration of travel on participation rates and participants' satisfaction: results from a pilot study at one study centre in Pretest 2 of the German National Cohort
BMJ Open., 5 (8)

Schweitzer A., Krause G., Pessler F., Akmatov M.K. (2015)
Improved coverage and timing of childhood vaccinations in two post-Soviet countries, Armenia and Kyrgyzstan
BMC Public Health, 15 (1)

Schweitzer A., Della Beffa C., Akmatov M.K., Narchi H., Abaev Y.K., ... , Sherry D.D., Pessler F. (2015)
Primary Osteomyelitis of the Sternum in the Pediatric Age Group: Report of a New Case and Comprehensive Analysis of Seventy-four Cases
Pediatr.Infect.Dis.J, 34 (4)

Mall S., Akmatov M.K., Schultze A., Ahrens W., Obi N., ... , Pessler F., Krause G. (2014)
Web-based questionnaires to capture acute infections in long-term cohorts : Findings of a feasibility study
Bundesgesundheitsblatt.Gesundheitsforschung.Gesundheitsschutz., 57 (11)

Akmatov M.K., Mehraj J., Gatzemeier A., Strömpl J., Witte W., ... , Krause G., Pessler F. (2015)
Erratum to 'Serial home-based self-collection of anterior nasal swabs to detect Staphylococcus aureus carriage in a randomized population-based study in Germany'. [International Journal of Infectious Diseases (2014) 4-10, doi:10.1016/j.ijid.2014.01.021]
Int.J.Infect.Dis., 30

Akmatov M.K., Kimani-Murage E., Pessler F., Guzmán C.A., Krause G., ... , Kreienbrock L., Mikolajczyk R.T. (2014)
Evaluation of invalid vaccine doses in 31 countries of the WHO African Region
Vaccine, 33

Kuhn A., Nieters A., Kottgen A., Goek O.N., Michels K., Nothlings U., Jacobs G., Meisinger C., Pessler Frank, Akmatov M.K., Kuhnisch J., Moebus S., Glocker E., Naus S., Keimling M., Leitzmann M., Linseisen J., Sarioglu H., von Toerne C., Hauck S.M., Wallaschofski H., ... , Wichmann H.E., Illig T. (2014)
Feasibility and quality development of biomaterials in the pretest studies of the German National Cohort
Bundesgesundheitsblatt.Gesundheitsforschung.Gesundheitsschutz., 57 (11)

Castell S., Akmatov M.K., Obi N., Flesh-Janys D., Nieters A., Kemmling Y., ... , Pessler F., Krause G. (2014)
Test-retest reliability of an infectious disease questionnaire and evaluation of self-assessed vulnerability to infections : Findings of Pretest 2 of the German National Cohort
Bundesgesundheitsblatt.Gesundheitsforschung.Gesundheitsschutz., 57 (11)

Schultze A., Akmatov M.K., Castell S., Karch A., Ahrens W., Gunther K., Schlenz H., Flesch-Janys D., Obi N., ... , Pessler F., Krause G. (2014)
Collection of vaccination data in the German National Cohort : Findings of a feasibility study in three study centers
Bundesgesundheitsblatt.Gesundheitsforschung.Gesundheitsschutz., 57 (11)

Schultze A., Akmatov M.K., Andrzejak M., Karras N., Kemmling Y., Maulhardt A., Wieghold S., Ahrens W., Gunther K., Schlenz H., ... , Krause G., Pessler F. (2014)
Comparison of stool collection on site versus at home in a population-based study : Feasibility and participants' preference in Pretest 2 of the German National Cohort
Bundesgesundheitsblatt.Gesundheitsforschung.Gesundheitsschutz., 57 (11)

Sievers C., Akmatov M.K., Kreienbrock L., Hille K., Ahrens W., Gunther K., Flesch-Janys D., Obi N., Michels K.B., Fricke J., Greiser K.H., Kaaks R., Peter H.H., Pessler F., ... , Nieters A., Krause G. (2014)
Evaluation of a questionnaire to assess selected infectious diseases and their risk factors : Findings of a multicenter study
Bundesgesundheitsblatt.Gesundheitsforschung.Gesundheitsschutz., 57 (11)

Mehraj J., Akmatov M.K., Strömpl J., Gatzemeier A., Layer F., Werner G., Pieper D.H., Medina E., Witte W., ... , Pessler F., Krause G. (2014)
Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus Nasal Carriage in a Random Sample of Non-Hospitalized Adult Population in Northern Germany
PLoS ONE, 9 (9)

Akmatov M.K., Mehraj J., Gatzemeier A., Strömpl Julia, Witte W., ... , Krause G., Pessler F. (2014)
Serial home-based self-collection of anterior nasal swabs to detect Staphylococcus aureus carriage in a randomized population-based study in Germany
International Journal of Infectious Diseases, 25

Novoselova N., Della Beffa Cristina, Wang Junxi, Li J., Pessler Frank, Klawonn Frank (2014)
HUM calculator and HUM package for R: easy-to-use software tools for multicategory receiver operating characteristic analysis
Bioinformatics, 30 (11)

Preusse M., Tantawy M.A., Klawonn F., Schughart K., Pessler F. (2013)
Infection- and procedure-dependent effects on pulmonary gene expression in the early phase of influenza A virus infection in mice
BMC Microbiology, 13 (1)

Pessler Frank, Ogdie A.R., Mayer C.T., Kretzschmar W.W., Dai L., Elsaman A.M., Einhorn E., ... , Krenn V., Schumacher H.R. (2014)
Amyloid arthropathy associated with multiple myeloma: polyarthritis without synovial infiltration of CD20+ or CD38+ cells
Amyloid, 21

Elsaman A.M., Radwan A.R., Akmatov M.K., Della Beffa C., Walker A., Mayer C.T., Dai L., Nativ S., Rygg M., Atsali E., Saijo K., Ogdie A.R., Srinivasulu N., Fathi N., ... , Schumacher H.R., Pessler F. (2013)
Amyloid arthropathy associated with multiple myeloma: A systematic analysis of 101 reported cases
Seminars in Arthritis and Rheumatism, 43 (3)

Klawonn F., Jayaram B., Crull K., Kukita A., Pessler F. (2013)
Analysis of contingency tables based on generalized median polish with power transformations and non-additive models
Health Information Science & Systems, 1

Akmatov M.K., Mikolajczyk R.T., Krumkamp R., Wörmann T., Chu J.J., Paetzelt G., Reintjes R., ... , Pessler F., Krämer A. (2012)
Availability of indicators of migration in the surveillance of HIV, tumberculosis and hepatitis B in the European Union - a short note
Journal of Public Health, 20

Della Beffa Cristina, Slansky E., Pommerenke C., Klawonn Frank, Li J., Dai L., ... , Schumacher H.R. Jr., Pessler Frank (2013)
The relative composition of the inflammatory infiltrate as an additional tool for synovial tissue classification
PLoS ONE, 8 (8)

Zou C.J., Zhu L.J., Li Y.H., Mo Y.Q., Zheng D.H., Ma J.D., Ou-Yang X., ... , Pessler Frank, Dai L. (2013)
The association between hepatitis B virus infection and disease activity, synovitis, or joint destruction in rheumatoid arthritis
Clinical Rheumatology, 32 (6)

Luksch H., Romanowski M.J., Chara O., Tungler V., Caffarena E.R., Heymann M.C., Lohse P., Aksentijevich I., Remmers E.F., Flecks S., Quoos N., Gramatte J., Petzold C., Hofmann S.R., Winkler S., Pessler F., Kallinich T., Ganser G., Nimtz-Talaska A., Baumann U., Runde V., Grimbacher B., Birmelin J., Gahr M., ... , Roesler J., Rosen-Wolff A. (2013)
Naturally occurring genetic variants of human caspase-1 differ considerably in structure and the ability to activate interleukin-1b[beta]
Human Mutation, 34 (1)

Akmatov M.K., Gatzemeier Anja, Schughart Klaus, Pessler Frank (2012)
Equivalence of self- and staff-collected nasal swabs for the detection of viral respiratory pathogens
PLoS ONE, 7 (11)

Akmatov M.K., Pessler F. (2011)
Self-collected nasal swabs to detect infection and colonization: a useful tool for population-based epidemiological studies?3356
International Journal of Infectious Diseases, 15 (9)

Klawonn Frank, Crull Katja, Kukita A., Pessler Frank (2012)
Median polish with power transformations as an alternative for the analysis of contingency tables with patient data
LNCS (Lecture Notes in Computer Sience (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)), 7231

Winkler S., Dai L., Hauck F., Dinger J., Pessler Frank (2012)
Primary osteomyelitis of the clavicle in the newborn period
Pediatric Infectious Disease Journal, 31 (2)

Della Beffa Cristina*, Klawonn Frank*, Menetski J.P., Schumacher H.R., Pessler Frank* (2011)
Evaluation of glyceraldehyde-3-phosphate, prolylpeptidyl isomerase A, and a set of stably expressed genes as reference mRNAs in urate crystal inflammation
BMC Research Notes, 4

Mo Y.Q., Dai L., Zheng D.H., Zhu L.J., Wei X.N., Pessler Frank*, ... , Shen J., Zhang B.Y. (2011)
Synovial Infiltration with CD79a-positive B Cells, But Not Other B Cell Lineage Markers, Correlates with Joint Destruction in Rheumatoid Arthritis
Journal of Rheumatology, 38 (11)

Akmatov M.K., Krebs S., Preusse M., Gatzemeier A., Frischmann U., ... , Schughart Klaus*, Pessler F. (2011)
E-mail-based symptomatic surveillance combined with self-collection of nasal swabs: a new tool for acute respiratory infection epidemiology
International Journal of Infectious Diseases, 15 (11)

Kukita A., Kukita T., Nagata K., Teramachi J., Li Y.J., Yoshida H., Miyamoto H., Gay S., ... , Pessler Frank*, Shobuike T. (2011)
The transcription factor FBI-1/OCZF/LRF is expressed in osteoclasts and regulates RANKL-induced osteoclast formation in vitro and in vivo
Arthritis and Rheumatism, 63 (9)

von Jagwitz M., Pessler F., Akmatov M.K., Range U., Vogelberg C. (2011)
Reduced breath condensate pH in asymptomatic children with prior wheezing as a risk factor for asthma
Journal of Allergy and Clinical Immunology, 128 (1)

Dai L., Wei X.N., Zheng D.H., Mo Y.Q., Pessler Frank*, Zhang B.Y. (2011)
Effective treatment of Kimura's disease with leflunomide in combination with glucocorticoids
Clinical Rheumatology, 30 (6)

Hauck F., Lee-Kirsch M.A., Aust D., Roesler J., Pessler Frank* (2010)
Complement C2 deficiency disarranging innate and adaptive humoral immune responses in a pediatric patient: Treatment with rituximab
Arthritis Care Res (Hoboken.), 63 (3)

Gemulla G., Pessler Frank* (2011)
Can Norovirus Infection Lead to a Postinfectious Arthritis? Report of 2 Possible Cases
Klinische Pädiatrie, 223 (1)

Bruck N., Suttorp M., Kabus M., Heubner G., Gahr M., Pessler Frank* (2011)
Rapid and sustained remission of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome through treatment with anakinra and corticosteroids
Journal of Clinical Rheumatology, 17 (1)

Slansky E., Li J., Haupl T., Morawietz L., Krenn V., Pessler Frank* (2010)
Quantitative determination of the diagnostic accuracy of the synovitis score and its components
Histopathology, 57 (3)

Ogdie A., Schumacher H.R. Jr., Dai L., Chen L.X., Einhorn E., Pessler Frank* (2010)
Synovial biopsy findings in arthritis associated with hepatitis C virus infection
Journal of Rheumatology, 37 (6)

Bruck N., Gahr M., Pessler F. (2010)
Transient oligoarthritis of the lower extremity following influenza B virus infection: Case report
Pediatric Rheumatology, 8

Ogdie A., Li J., Dai L., Paessler M.E., Yu X., az-Torne C., Akmatov M.K., ... , Schumacher H.R., Pessler F. (2010)
Identification of broadly discriminatory tissue biomarkers of synovitis with binary and multicategory receiver operating characteristic analysis
Biomarkers, 15 (2)