Publikationsdatenbank des HZI

Kempf,H., Hatzikirou,H., Bleicher,M., Meyer-Hermann,M. (2013)

In silico analysis of cell cycle synchronisation effects in radiotherapy of tumour spheroids

PLoS Computational Biology 9 (11)

DOI: 10.1371/journal.pcbi.1003295 HZI-Repositorium PubMed

Steinbach,A., Maurer,C.K., Weidel,E., Henn,C., Brengel,C., ... , Hartmann,Rolf W., Negri,M. (2013)

Molecular basis of HHQ biosynthesis: molecular dynamics simulations, enzyme kinetic and surface plasmon resonance studies

BMC Biophysics 6 (1)

DOI: 10.1186/2046-1682-6-10 HZI-Repositorium PubMed

Sahner,J.H., Groh,M., Negri,M., Haupenthal,Jörg, Hartmann,Rolf W. (2013)

Novel small molecule inhibitors targeting the "switch region" of bacterial RNAP: structure-based optimization of a virtual screening hit

European Journal of Medicinal Chemistry 65

Perspicace,E., Giorgio,A., Carotti,A., Marchais-Oberwinkler,S., Hartmann,Rolf W. (2013)

Novel N-methylsulfonamide and retro-N-methylsulfonamide derivatives as 17b[beta]-hydroxysteroid dehydrogenase type 2 (17b[beta]-HSD2) inhibitors with good ADME-related physicochemical parameters

European Journal of Medicinal Chemistry 69

DOI: 10.1016/j.ejmech.2013.08.026 PubMed

Lu,C., Maurer,C.K., Kirsch,B., Steinbach,A., Hartmann,Rolf W. (2014)

Overcoming unexpected functional inversion of PqsR antagonist in Pseudomonas aeruginosa led to the first in vivo potent anti-virulence agent targeting pqs quorum sensing

Angewandte Chemie 53 (4)

DOI: 10.1002/anie.201307547 HZI-Repositorium PubMed

Hinsberger,S., Husecken,K., Groh,M., Negri,M., Haupenthal,J., Hartmann,Rolf W. (2013)

Discovery of Novel Bacterial RNA Polymerase Inhibitors: Pharmacophore-Based Virtual Screening and Hit Optimization

Journal of Medicinal Chemistry 56

Grombein,C.M., Hu,Q., Heim,R., Huch,V., Hartmann,Rolf W. (2013)

Unexpected results of a S N,Ar

Tetrahedron Letters 54

DOI: 10.1016/j.tetlet.2013.09.111 HZI-Repositorium PubMed

Gobbi,S., Hu,Q., Negri,M., Zimmer,C., Belluti,F., Rampa,A., ... , Hartmann,Rolf W., Bisi,A. (2013)

Modulation of cytochromes P450 with xanthone-based molecules: from aromatase to aldosterone synthase and steroid 11beta-hydroxylase inhibition

Journal of Medicinal Chemistry 56 (4)

DOI: 10.1021/jm301844q

Elgaher,W.A.M., Fruth,M., Groh,M., Hartmann,Rolf W. (2013)

Expanding the scaffold for bacterial RNA polymerase inhibitors: Design, synthesis and structure activity relationships of ureido-heterocyclic-carboxylic acids

RSC Advances

DOI: 10.1039/C3RA45820B HZI-Repositorium PubMed

Nermin,S.A., Ali,A.H., El-Nashar,S.M., Gary,B.D., Fajardo,A.M., Tinsley,H.N., Piazza,G.A., ... , Negri,M., Abadi,A.H. (2012)

Exploring the PDE5 H-pocket by ensemble docking and structure-based design and synthesis of novel b[beta]-carboline derivatives

European Journal of Medicinal Chemistry 57

DOI: 10.1016/j.ejmech.2012.09.029 HZI-Repositorium PubMed