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If an intestinal inhabitant such as the bacterium Escherichia coli (E. coli) becomes resistant to many antibiotics, it can cause serious health problems if it enters the bloodstream. How can such potentially dangerous multi-resistant bacteria be effectively removed from the gut? Researchers from the Helmholtz Centre for Infection Research (HZI), in collaboration with researchers from Hannover Medical School (MHH), explored this question in their latest study.

03.07.2025

HZI Campus

Pseudocolored cells of Pseudomonas aeruginosa

News

An international research team led by the Helmholtz Centre for Infection Research (HZI) has discovered a new strategy used by the human pathogen Pseudomonas aeruginosa to adapt to its host. In the journal Proceedings of the National Academy of Sciences (PNAS), the researchers demonstrate that epigenetic processes can lead to the emergence of distinct sub-populations within genetically identical bacterial populations. This heterogeneity may be a key for bacteria to establish successful infections.

02.07.2025

HZI Campus

TWINCORE

BRICS

News

Habitat loss, climate change, and globalization create new transmission routes for pathogens. Therefore, the One Health approach considers humans, animals and nature together. Prof. Fabian Leendertz is founding director of the Helmholtz Institute for One Health (HIOH) in Greifswald, which links health research, ecology, and prevention to better prepare for future pandemics. In this episode of the HZI podcast “InFact”, Leendertz explains how zoonoses, or diseases that jump from animals to humans, develop, and why protecting the environment is central to this process.

02.07.2025

HIOH

News

A research project at the Helmholtz Institute for One Health (HIOH), a site of the Helmholtz Centre for Infection Research (HZI), has been awarded the Undine Award 2025 in the “Habitat” category. The prize was presented in Stuttgart. In the award-winning project, a research team led by Prof. Katharina Schaufler is investigating antimicrobial resistance (AMR) in the surface water of the Greifswald Bodden. Targeted science communication is also an important part of the project in order to raise public awareness of the issue. Schaufler heads the department “Epidemiology and Ecology of Antimicrobial Resistance” at the HIOH and receives prize money of 20,000 euros and an image film with the Undine Award.

19.06.2025

HIOH

News

Researchers at the Helmholtz Centre for Infection Research (HZI) have contributed to a study by the Medical Center Hamburg-Eppendorf (UKE) that has uncovered a new mechanism of neuron damage in the autoimmune disease multiple sclerosis (MS). Until now, it was unclear how inflammation in MS reduces protein degradation and leads to their harmful accumulation in neurons. A combination of new molecular biological, biochemical, and genetic methods enabled the international research team to identify a previously unknown mechanism of impaired protein degradation in inflamed neurons and its key regulator, the immunoproteasome.

18.06.2025

HZI Campus

Electron microscope image of Bacteroides thetaiotaomicron, illustrating the differences in the size of the bacterial cells.

News

Despite being genetically identical, bacteria can vary considerably in shape and size. Whether these variations affect bacterial function has remained an open question. Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) and the Chair of Microbiology of the Julius-Maximilians-Universität Würzburg (JMU) have now characterized the functional differences between various forms of the gut bacterium Bacteroides thetaiotaomicron. They demonstrated a link between cell type and metabolic function. These findings offer deeper insights into microbial gut diversity and pave the way for new possibilities in microbiome-based therapies. The study was recently published in the journal Cell Reports.

17.06.2025

HZI Campus

HIRI

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HZI in the media

tools.” – Dr. Anya Sharma, Virologist at the Helmholtz Centre for Infection Research.

Looking Ahead: The Long-Term Implications of

08.01.2026

ARCHYDE

Beisel at Germany's Helmholtz Institute for RNA-based Infection Research in Würzburg and Dirk Heinz at the Helmholtz Center for Infection

07.01.2026

News Medical

... basierte Infektionsforschung (HIRI) in Würzburg nachweisen. Gemeinsam mit dem Braunschweiger Helmholtz-Zentrum für Infektionsforschung ...

07.01.2026

DeutschesGesundheitsPortal

consisting of Hannover Medical School (MHH), the Helmholtz Centre for Infection Research (HZI) in Braunschweig, and the Leibniz Institute in

07.01.2026

Trading View

... haben nun die Studienautoren vom HIRI ‒ einem Standort des Braunschweiger Helmholtz-Zentrums für Infektionsforschung (HZI) in ...

02.01.2026

Biermann Medizin

... bis zur Medikamentenentwicklung", sagt Josef Penninger, wissenschaftlicher Geschäftsführer des HZI und Leiter der Abteilung Innovative ...

30.12.2025

Tagesschau

Erkrankungen. Eine Arbeitsgruppe des TWINCORE Helmholtz Zentrum für Infektionsforschung ( HZI ) und der Medizinischen Hochschule Hannover ( ...

30.12.2025

Deutsches Ärzteblatt

Forschungsteam um Tobias Gulder, Abteilungsleiter am Helmholtz-Institut für Pharmazeutische Forschung Saarland (HIPS), ist es ...

29.12.2025

Biermann Medizin

... des Leibniz Lungenzentrums Borstel, des Helmholtz-Instituts für Pharmazeutische Forschung Saarland sowie weiterer wissenschaftlicher ...

29.12.2025

Das PTA Magazin

Dr. Rolf Müller, Managing Director of Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), were both named laureates of the

22.12.2025

Research Information

... ein Interview mit Josef Penninger geführt . Er ist wissenschaftlicher Geschäftsführer des Helmholtz-Zentrum für Infektionsforschung in ...

21.12.2025

T3N

Forschende vom Würzburger Helmholtz-Institut für RNA-basierte Infektionsforschung (HIRI), einem Standort des Braunschweiger Helmholtz- ...

17.12.2025

Verband Deutscher Biologen e.V.

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