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Group photo of the HIRI scientists involved in the study

News

To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers from the Würzburg Helmholtz Institute for RNA-based Infection Research and the Helmholtz AI Cooperative applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before. The findings were published today in the journal Genome Biology.

11.01.2024

HIRI

Decorative image to represent the new databases

News

Modern pharmaceutical research generates large amounts of data faster than ever before. To analyze and evaluate this data, it is collected and structured in extensive databases and thus provides the basis for the development of new active ingredients. Researchers at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) have now published two such databases. While the "ABC-HuMi" database focuses on genetic data from microorganisms that colonize humans, "ZEBRA" provides a high-resolution cell atlas of the human and mouse brain. Both databases were published in the annual database issue of the journal Nucleic Acids Research.

09.01.2024

HIPS

News

Despite the end of the pandemic, COVID-19 continues to pose a serious health threat. Most individuals have established robust immune protection and do not develop severe disease but the infection can still lead to marked and sometimes long-lasting disease symptoms. In the late summer of 2023 a new SARS-CoV-2 variant emerged, BA.2.86 (Pirola), which, based on genetics, differs markedly from all previously circulating variants.

09.01.2024

HZI Campus

Group Picture of Participants of the ENLIGHT-TEN+ Winter School

News

From 13 to 17 November 2023, 28 young scientists gathered at BAYER in Berlin to take part in the Winter School for Translational Medical Research and Drug Development organized by ENLIGHT-TEN+ and EATRIS. Experts from science and industry provided in-depth insights into the basics of drug production and introduced the young scientists to the processes through interactive exercises and case studies. BAYER is a member of the ENLIGHT-TEN+ consortium and was primarily responsible for organizing the Winter School.

21.12.2023

HZI Campus

Story

Vaccinations do not always live up to what we would want them to do – so far, anyway. But they are still invaluable for our health and life in our communities.

12.12.2023

HZI Campus

[Translate to English:] Endogener ASC-Speck, abgebildet in 3D mit dSTORM. © iScience, CC-BY-4.0

News

A central component of the human immune system, the NLRP3 inflammasome plays an important role in fighting off infections. However, its chronic activation is also implicated in a variety of common diseases, such as Alzheimer’s, Parkinson’s, multiple sclerosis, atherosclerosis, gout, and type II diabetes. The NLRP3 inflammasome occurs primarily in specialized immune cells in the blood and elsewhere. It is a dense complex in which several proteins interact with each other. A key protein in this complex is known by the abbreviation ASC. In non-activated immune cells, it is distributed homogeneously throughout the cell. If the NLRP3 inflammasome is activated, all of the ASC protein present in the cell aggregates in the inflammasome complex. Under an ordinary fluorescence microscope, the ASC protein, once labeled, appears as a single, bright, nearly round spot. Due to the small size and high density of this ASC speck, scientists have been unable to elucidate details of its structure inside cells. Different models were proposed in the scientific literature but a comprehensive understanding was missing.

11.12.2023

HZI Campus

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HZI in the media

... haben. Ein Forschungsteam des Helmholtz-Instituts für RNA-basierte Infektionsforschung (HIRI) in Würzburg hat in Zusammenarbeit ...

14.04.2026

PresseBox - DE

... der Infektion und Nozizeption“ am Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig. Nozizeption ist der Fachbegriff ...

14.04.2026

Verband Deutscher Biologen e.V.

... recht nicht bei Fabian Leendertz, der in Greifswald das „Helmholtz-Institut für One Health“ leitet. Im ...

14.04.2026

FAZ.NET

... sich auch das Helmholtz-Institut für Pharmazeutische Forschung Saarland ( HIPS ), das Helmholtz-Zentrum für Infektionsforschung ( HZI ) ...

09.04.2026

Deutsches Ärzteblatt

... ÖAW in Wien und nun Gruppenleiter am Helmholtz Zentrum für Infektionsforschung in Braunschweig, forscht an ...

08.04.2026

DerStandard.de

... group within the Microstar Program at the Helmholtz Centre for Infection Research (HZI) and a ...

31.03.2026

Informations Dienst Wissenschaft

... an der Medizinischen Hochschule Hannover und am Helmholtz Institut für Infektionen in Braunschweig die Wirkung ...

28.03.2026

Hamburger Abendblatt

led by wildlife veterinarian Fabian Leendertz, who heads the Helmholtz Institute for One Health, took hundreds of samples from meat and

27.03.2026

Science.org

Gesellschaft. Apropos Standort Braunschweig: Auch das Helmholtz-Zentrum für Infektionsforschung HZI, in dessen Räumlichkeiten auf dem ...

27.03.2026

transkript

Helmholtz Centre for Infection Research

After infection with SARS-CoV-2, up to 10 percent of people in Germany go on to develop Long COVID.

26.03.2026

Mirage.News

... von verschiedenen Hörnchen, wie jüngste Erkenntnisse des Helmholtz Instituts für One Health in Greifswald kürzlich ...

26.03.2026

Tagesschau

zur Bekämpfung der Tuberkulose und des Helmholtz-Zentrums für Infektionsforschung erstellt. Zahlreiche weitere Fachgesellschaften und

24.03.2026

Deutsches Ärzteblatt

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