Author count: 15
Garcia R., Popoff A., Bader C.D., Löhr J., Walesch S., Walt C., Boldt J., Bunk B., Haeckl F.P.J., Gunesch A.P., Birkelbach J., Nübel U., Pietschmann T., ... , Bach T., Müller R.
(2024)
Discovery of the Pendulisporaceae: An extremotolerant myxobacterial family with distinct sporulation behavior and prolific specialized metabolism
Chem,
10
Author count: 12
Lauber C., Zhang X., Vaas J., Klingler F., Mutz P., Dubin A., Pietschmann T., Roth O., Neuman B.W., Gorbalenya A.E., ... , Bartenschlager R., Seitz S.
(2024)
Deep mining of the Sequence Read Archive reveals major genetic innovations in coronaviruses and other nidoviruses of aquatic vertebrates
PLoS Pathogens,
20
(4/ April)
Author count: 11
Frericks N., Brown R.J.P., Reinecke B.M., Herrmann M., Brüggemann Y., Todt D., Miskey C., Vondran F.W.R., Steinmann E., ... , Pietschmann T., Sheldon J.
(2024)
Unraveling the dynamics of hepatitis C virus adaptive mutations and their impact on antiviral responses in primary human hepatocytes
J.Virol.,
98
(3)
Author count: 32
Sake S.M., Zhang X., Rajak M.K., Urbanek-Quaing M., Carpentier A., Gunesch A.P., Grethe C., Matthaei A., R++ckert J., Galloux M., Larcher T., Le Goffic R., Hontonnou F., Chatterjee A.K., Johnson K., Morwood K., Rox K., Elgaher W.A.M., Huang J., Wetzke M., Hansen G., Fischer N., El+®ou+½t J.F., Rameix-Welti M.A., Hirsch A.K.H., Herold E., Empting M., Lauber C., Schulz T.F., Krey T., ... , Haid S., Pietschmann T.
(2024)
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor
Nature Communications,
15
(1)
Author count: 22
Haid S., Matthaei A., Winkler M., Sake S.M., Gunesch A.P., Milke V., Köhler N.M., Rückert J., Vieyres G., Kühl D., Nguyen T.-T., Göhl M., Lasswitz L., Zapatero-Belinchon F.J., Brogden G., Gerold G., Wiegmann B., Bilitewski U., Brown R.J.P., Brönstrup M., ... , Schulz T.F., Pietschmann T.
(2024)
Repurposing screen identifies novel candidates for broad-spectrum coronavirus antivirals and druggable host targets
Antimicrob.Agents Chemother.
Author count: 11
Matthaei A., Joecks S., Frauenstein A., Bruening J., Bankwitz D., Friesland M., Gerold G., Vieyres G., Kaderali L., ... , Meissner F., Pietschmann T.
(2024)
Landscape of protein-protein interactions during hepatitis C virus assembly and release
Microbiol.Spectr.,
12
(2)
Author count: 15
Pink I., Hennigs J.K., Ruhl L., Sauer A., Boblitz L., Huwe M., Fuge J., Falk C.S., Pietschmann T., de Zwaan M., Prasse A., Kluge S., Klose H., ... , Hoeper M.M., Welte T.
(2023)
Blood T cell phenotypes correlate with fatigue severity in post-acute sequelae of COVID-19
Infection
Author count: 9
Meister T.L., Friesland M., Frericks N., Wetzke M., Haid S., Steinmann J., Todt D., ... , Pietschmann T., Steinmann E.
(2023)
Virucidal activity of oral, hand, and surface disinfectants against respiratory syncytial virus
J.Hosp.Infect.,
141
(Nov 2023)
Author count: 10
Liang T.J., Law J.L.M., Pietschmann T., Ray S.C., Bukh J., Bull R., Chung R.T., Tyrrell D.L., ... , Houghton M., Rice C.M.
(2023)
Challenge Inoculum for Hepatitis C Virus Controlled Human Infection Model
Clin.Infect.Dis.,
77
Author count: 10
Stahl Y., Kabar I., Heinzow H., Maasoumy B., Bremer B., Wedemeyer H., Schmidt H.H.-J., Pietschmann T., ... , Schlevogt B., Behrendt P.
(2023)
Enhanced monitoring and detection of recent genotype 3 hepatitis E virus infection through urine antigen testing
Emerg.Microbes Infect.,
12
(2)
Author count: 10
Zhang Y., Kinast V., Sheldon J., Frericks N., Todt D., Zimmer M., Caliskan N., Brown R.J.P., ... , Steinmann E., Pietschmann T.
(2023)
Mouse Liver-Expressed Shiftless Is an Evolutionarily Conserved Antiviral Effector Restricting Human and Murine Hepaciviruses
Microbiol.Spectr.
Author count: 7
Lange F., Garn J., Anagho H.A., Vondran F.W.R., von Hahn T., ... , Pietschmann T., Carpentier A.
(2023)
Hepatitis D virus infection, innate immune response and antiviral treatments in stem cell-derived hepatocytes
Liver Int.
Author count: 2
Vieyres G., Pietschmann T.
(2023)
The role of human lipoproteins for hepatitis C virus persistence
Current Opinion in Virology,
60
Author count: 19
Sake S.M., Kosch C., Blockus S., Haid S., Gunesch A.P., Zhang X., Friesland M., Trummer S.B., Grethe C., Kühnel A., Rückert J., Duprex W.P., Huang J., Rameix-Welti M.A., Empting M., Fischer N., Hirsch A.K.H., ... , Schulz T.F., Pietschmann T.
(2022)
Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages
Antimicrob.Agents Chemother.
Author count: 13
Keller L., Oueis E., Kaur A., Safaei N., Kirsch S.H., Gunesch A.P., Haid S., Rand U., Cicin-Sain L., Fu C., Wink J., ... , Pietschmann T., Müller R.
(2022)
Persicamidines - Unprecedented Sesquarterpenoids with Potent Antiviral Bioactivity against Coronaviruses
Angew.Chem.Int.Ed Engl.
Author count: 12
Haack P.A., Harmrolfs K., Bader C.D., Garcia R., Gunesch A.P., Haid S., Popoff A., Voltz A., Kim H., Bartenschlager R., ... , Pietschmann T., Müller R.
(2022)
Thiamyxins: Structure and Biosynthesis of Myxobacterial RNA-Virus Inhibitors
Angew.Chem.Int.Ed Engl.
Author count: 12
Baier C., Huang J., Reumann K., Indenbirken D., Thol F., Koenecke C., Ebadi E., Heim A., Bange F.C., Haid S., ... , Pietschmann T., Fischer N.
(2022)
Target capture sequencing reveals a monoclonal outbreak of respiratory syncytial virus B infections among adult hematologic patients
Antimicrob.Resist.Infect.Control,
11
(1)
Author count: 10
Reinecke B., Frericks N., Lauber C., Dinkelborg K., Matthaei A., Vondran F.W.R., Behrendt P., Haid S., ... , Brown R.J.P., Pietschmann T.
(2022)
The Human Liver-Expressed Lectin CD302 Restricts Hepatitis C Virus Infection
J Virol.
Author count: 13
Gömer A., Brown R.J.P., Pfaender S., Deterding K., Reuter G., Orton R., Seitz S., Bock C.T., Cavalleri J.M.V., Pietschmann T., Wedemeyer H., ... , Steinmann E., Todt D.
(2022)
Intra-host analysis of hepaciviral glycoprotein evolution reveals signatures associated with viral persistence and clearance
Virus Evol.,
8
(1)
Author count: 12
Wetzke M., Funken D., Lange M., Bejo L., Haid S., Monteiro J.G.T., Schütz K., Happle C., Schulz T.F., Seidenberg J., ... , Pietschmann T., Hansen G.
(2022)
IRIS: Infection with RespIratory Syncytial Virus in infants-a prospective observational cohort study
BMC Pulm Med,
22
(1)
Author count: 32
Schuhenn J., Meister T.L., Todt D., Bracht T., Schork K., Billaud J.N., Elsner C., Heinen N., Karakoese Z., Haid S., Kumar S., Brunotte L., Eisenacher M., Di Y., Lew J., Falzarano D., Chen J., Yuan Z., Pietschmann T., Wiegmann B., Uebner H., Taube C., Le-Trilling V.T.K., Trilling M., Krawczyk A., Ludwig S., Sitek B., Steinmann E., Dittmer U., Lavender K.J., ... , Sutter K., Pfaender S.
(2022)
Differential interferon- a
Proc.Natl.Acad.Sci.U.S.A.,
119
(8)
Author count: 28
Paulsen M., Zychlinsky Scharff A., de Cassan K., Sugianto R.I., Blume C., Blume H., Christmann M., Hauß C., Illig T., Jonczyk R., Klopp N., Kopfnagel V., Lichtinghagen R., Lucas H., Luhr A., Mutschler F., Pietschmann T., Pott P.C., Prokein J., Schaefer P., Stahl F., Stanislawski N., von der Born J., Schmidt B.M.W., Heiden S., Stiesch M., ... , Memaran N., Melk A.
(2021)
Children and Adolescents' Behavioral Patterns in Response to Escalating COVID-19 Restriction Reveal Sex and Age Differences
J.Adolesc.Health
Author count: 25
Weber T., Potthoff J., Bizu S., Labuhn M., Dold L., Schoofs T., Horning M., Ercanoglu M.S., Kreer C., Gieselmann L., Vanshylla K., Langhans B., Janicki H., Ströh L.J., Knops E., Nierhoff D., Spengler U., Kaiser R., Bjorkman P.J., Krey T., Bankwitz D., Pfeifer N., Pietschmann T., ... , Flyak A.I., Klein F.
(2021)
Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization
Immunity.,
55
(2)
Author count: 12
Bader C.D., Panter F., Garcia R., Tchesnokov E.P., Haid S., Walt C., Spröer C., Kiefer A.F., Götte M., Overmann J., ... , Pietschmann T., Müller R.
(2022)
Sandacrabins - Structurally Unique Antiviral RNA Polymerase Inhibitors from a Rare Myxobacterium
Chemistry.
Author count: 3
Bankwitz D., Krey T., Pietschmann T.
(2022)
[Development approaches for vaccines against hepatitis C virus infections] / Entwicklungsansätze für Impfstoffe gegen Hepatitis-C-Virus-Infektionen
Bundesgesundheitsblatt.Gesundheitsforschung.Gesundheitsschutz.
(Jan)
Author count: 17
Zapatero-Belinchón F.J., Moeller R., Lasswitz L., Van Ham M., Becker M., Brogden G., Rosendal E., Bi W., Carriquí-Madronal B., Islam K., Lenman A., Gunesch A.P., Kirui J., Pietschmann T., Överby A.K., ... , Jänsch L., Gerold G.
(2021)
Fluvastatin mitigates SARS-CoV-2 infection in human lung cells
iScience,
24
(12)
Author count: 7
Nicolay W., Moeller R., Kahl S., Vondran F.W.R., Pietschmann T., ... , Kunz S., Gerold G.
(2021)
Characterization of rna sensing pathways in hepatoma cell lines and primary human hepatocytes
Cells,
10
(11)
Author count: 29
Ricke-Hoch M., Stelling E., Lasswitz L., Gunesch A.P., Kasten M., Zapatero-Belinchon F.J., Brogden G., Gerold G., Pietschmann T., Montiel V., Balligand J.L., Facciotti F., Hirsch E., Gausepohl T., Elbahesh H., Rimmelzwaan G.F., Höfer A., Kühnel M.P., Jonigk D., Eigendorf J., Tegtbur U., Mink L., Scherr M., Illig T., Schambach A., Pfeffer T.J., Hilfiker A., ... , Haverich A., Hilfiker-Kleiner D.
(2021)
Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease
PLoS ONE,
16
(8)
Author count: 19
Risso-Ballester J., Galloux M., Cao J., Le Goffic R., Hontonnou F., Jobart-Malfait A., Desquesnes A., Sake S.M., Haid S., Du M., Zhang X., Zhang H., Wang Z., Rincheval V., Zhang Y., Pietschmann T., Eléouet J.F., ... , Rameix-Welti M.A., Altmeyer R.
(2021)
A condensate-hardening drug blocks RSV replication in vivo
Nature,
595
(7868)
Author count: 6
Martin-Benlloch X., Lanfranchi D.A., Haid S., Pietschmann T., Davioud-Charvet E., Elhabiri M.
(2021)
Magnesium Complexes of Ladanein: A Beneficial Strategy for Stabilizing Polyphenolic Antivirals
European Journal of Inorganic Chemistry
Author count: 14
Jo W.K., Schadenhofer A., Habierski A., Kaiser F.K., Saletti G., Ganzenmueller T., Hage E., Haid S., Pietschmann T., Hansen G., Schulz T.F., Rimmelzwaan G.F., ... , Osterhaus A.D.M.E., Ludlow M.
(2021)
Reverse genetics systems for contemporary isolates of respiratory syncytial virus enable rapid evaluation of antibody escape mutants
Proc.Natl.Acad.Sci.U.S.A.,
118
(14)
Author count: 18
Zapatero-Belinchón F.J., Dietzel E., Dolnik O., Döhner K., Costa R., Hertel B., Veselkova B., Kirui J., Klintworth A., Manns M.P., P÷hlmann S., Pietschmann T., Krey T., Ciesek S., Gerold G., Sodeik B., ... , Becker S., von Hahn T.
(2019)
Characterization of the filovirus-resistant cell line SH-SY5Y reveals redundant role of cell surface entry factors
Viruses,
11
(3)
Author count: 19
Tegtmeyer B., Vieyres G., Todt D., Lauber C., Ginkel C., Engelmann M., Herrmann M., Pfaller C.K., Vondran F.W.R., Broering R., Vafadarnejad E., Saliba A.E., Puff C., Baumgärtner W., Miskey C., Ivics Z., Steinmann E., ... , Pietschmann T., Brown R.J.P.
(2021)
Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elements
J.Virol.,
95
(10)
Author count: 16
Bankwitz D., Bahai A., Labuhn M., Doepke M., Ginkel C., Khera T., Todt D., Ströh L.J., Dold L., Klein F., Klawonn F., Krey T., Behrendt P., Cornberg M., ... , McHardy A.C., Pietschmann T.
(2021)
Hepatitis C reference viruses highlight potent antibody responses and diverse viral functional interactions with neutralising antibodies
GUT
Author count: 42
Brown R.J.P., Tegtmeyer B., Sheldon J., Khera T., Anggakusuma, Todt D., Vieyres G., Weller R., Joecks S., Zhang Y., Sake S., Bankwitz D., Welsch K., Ginkel C., Engelmann M., Gerold G., Steinmann E., Yuan Q., Ott M., Vondran F.W.R., Krey T., Ströh L.J., Miskey C., Ivics Z., Herder V., Baumgärtner W., Lauber C., Seifert M., Tarr A.W., Mcclure C.P., Randall G., Baktash Y., Ploss A., Thi V.L.D., Michailidis E., Saeed M., Verhoye L., Meuleman P., Goedecke N., Wirth D., ... , Rice C.M., Pietschmann T.
(2020)
Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice
Sci Adv,
6
(45)
Author count: 11
Tran H.T.L., Morikawa K., Anggakusuma, Zibi R., Thi V.L.D., Penin F., Heim M.H., Quadroni M., Pietschmann T., ... , Gouttenoire J., Moradpour D.
(2020)
OCIAD1 is a host mitochondrial substrate of the hepatitis C virus NS3-4A protease
PLoS ONE,
15
(7)
Author count: 9
Wahlicht T., Vieyres G., Bruns S.A., Meumann N., Büning H., Hauser H., Schmitz I., ... , Pietschmann T., Wirth D.
(2020)
Controlled Functional Zonation of Hepatocytes in Vitro by Engineering of Wnt Signaling
ACS Synth.Biol.,
9
(7)
Author count: 5
Haid S., Grethe C., Bankwitz D., Grunwald T., Pietschmann T.
(2020)
Erratum: Correction for Haid et al., "Identification of a Human Respiratory Syncytial Virus Cell Entry Inhibitor by Using a Novel Lentiviral Pseudotype System" (Journal of virology (2015) 90 6 (3065-3073) PII: e01690-19)
J.Virol.,
94
(14)
Author count: 5
Vieyres G., Reichert I., Carpentier A., Vondran F.W.R., Pietschmann T.
(2020)
The ATGL lipase cooperates with ABHD5 to mobilize lipids for hepatitis C virus assembly
PLoS.Pathog.,
16
(6)
Author count: 9
Gunesch A.P., Zapatero-Belinchon F.J., Pinkert L., Steinmann E., Manns M.P., Schneider G., Pietschmann T., ... , Brönstrup M., von Hahn T.
(2020)
Filovirus antiviral activity of cationic amphiphilic drugs is associated with lipophilicity and ability to induce phospholipidosis
Antimicrob.Agents Chemother.,
64
(8)
Author count: 9
Alberione M.P., Moeller R., Kirui J., Ginkel C., Doepke M., Ströh L.J., Machtens J.P., ... , Pietschmann T., Gerold G.
(2020)
Single-nucleotide variants in human CD81 influence hepatitis C virus infection of hepatoma cells
Med.Microbiol.Immunol.,
209
(4)
Author count: 19
Kinast V., Plociennikowska A., Anggakusuma, Bracht T., Todt D., Brown R.J., Boldanova T., Zhang Y., Brueggemann Y., Friesland M., Engelmann M., Vieyres G., Broering R., Vondran F.W.R., Heim M.H., Sitek B., Bartenschlager R., ... , Pietschmann T., Steinmann E.
(2020)
C19orf66 is an interferon-induced inhibitor of HCV replication that restricts formation of the viral replication organelle
J.Hepatol.,
73
(3)
Author count: 5
Köllmann C., Sake S.M., Jones P.G., Pietschmann T., Werz D.B.
(2020)
Protecting-Group-Mediated Diastereoselective Synthesis of C4-Methylated Uridine Analogs and Their Activity against the Human Respiratory Syncytial Virus
J.Org.Chem.,
85
(6)
Author count: 22
Blockus S., Sake S.M., Wetzke M., Grethe C., Graalmann T., Pils M., Le Goffic R., Galloux M., Prochnow H., Rox K., Huttel S., Rupcic Z., Wiegmann B., Dijkman R., Rameix-Welti M.A., Eleouet J.F., Duprex W.P., Thiel V., Hansen G., Brönstrup M., ... , Haid S., Pietschmann T.
(2020)
Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry
Antiviral Res.,
177
(May)
Author count: 5
Carpentier A., Sheldon J., Vondran F.W.R., Brown R.J.P., Pietschmann T.
(2020)
Efficient acute and chronic infection of stem cell-derived hepatocytes by hepatitis C virus
GUT,
69
(9)
Author count: 24
Prochnow H., Rox K., Birudukota N.V.S., Weichert L., Hotop S.K., Klahn P., Mohr K., Franz S., Banda D.H., Blockus S., Schreiber J., Haid S., Oeyen M., Martinez J.P., Süssmuth R.D., Wink J., Meyerhans A., Goffinet C., Messerle M., Schulz T.F., Kröger A., Schols D., ... , Pietschmann T., Brönstrup M.
(2020)
Labyrinthopeptins exert broad-spectrum antiviral activity through lipid-binding-mediated virolysis
J.Virol.,
94
(2)
Author count: 5
Köllmann C., Wiechert S.M., Jones P.G., Pietschmann T., Werz D.B.
(2019)
Synthesis of 4'/5'-Spirocyclopropanated Uridine and d-Xylouridine Derivatives and Their Activity against the Human Respiratory Syncytial Virus
Org.Lett.,
21
(17)
Author count: 3
Gerold G., Moeller R., Pietschmann T.
(2020)
Hepatitis C Virus Entry: Protein Interactions and Fusion Determinants Governing Productive Hepatocyte Invasion
Cold Spring Harb.Perspect.Med.,
10
(2)
Author count: 44
Gottschick C., Raupach-Rosin H., Langer S., Hassan L., Horn J., Dorendorf E., Caputo M., Bittner M., Beier L., Rübsamen N., Schlinkmann K., Zoch B., Guzmán C.A., Hansen G., Heselich V., Holzapfel E., Hübner J., Pietschmann T., Pieper D.H., Pletz M., Riese P., Schmidt-Pokrzywniak A., Hartwig S., Von Kaisenberg C., Aydogdu M., Buhles M., Dressler F., Eberl W., Haase R., von Koch F.E., Feidicker S., Frambach T., Franz H.G.B., Guthmann F., Koch H.G., Seeger S., Oberhoff C., Pauker W., Petry K.U., Schild R.L., Tchirikov M., Röhrig E., ... , Karch A., Mikolajczyk R.
(2019)
Erratum: Cohort profile: The LoewenKIDS Study - Life-course perspective on infections, the microbiome and the development of the immune system in early childhood (International Journal of Epidemiology (2019) DOI: 10.1093/ije/dyz001)
Int.J.Epidemiol.,
48
(4)
Author count: 14
Kinast V., Leber S.L., Brown R.J.P., Vieyres G., Behrendt P., Essbach C., Strnad P., Vondran F.W.R., Cornberg M., Wex C., Pietschmann T., Haybaeck J., ... , Todt D., Steinmann E.
(2019)
Identification of Keratin 23 as a Hepatitis C Virus-Induced Host Factor in the Human Liver
Cells,
8
(6)
Author count: 7
Martin-Benlloch X., Haid S., Novodomska A., Rominger F., Pietschmann T., ... , Davioud-Charvet E., Elhabiri M.
(2019)
Physicochemical Properties Govern the Activity of Potent Antiviral Flavones
ACS Omega,
4
(3)
Author count: 2
Vieyres G., Pietschmann T.
(2019)
HCV Pit Stop at the Lipid Droplet: Refuel Lipids and Put on a Lipoprotein Coat before Exit
Cells,
8
(3)
Author count: 2
Pietschmann T., Brown R.J.P.
(2019)
Hepatitis C Virus
Trends in Microbiology,
27
(4)
Author count: 43
Gottschick C., Raupach-Rosin H., Langer S., Hassan L., Horn J., Dorendorf E., Caputo M., Bittner M., Beier L., Rübsamen N., Schlinkmann K., Zoch B., Guzmán C.A., Hansen G., Heselich V., Holzapfel E., Hübner J., Pietschmann T., Pieper D.H., Pletz M., Riese P., Schmidt-Pokrzywniak A., Hartwig S., von Kaisenberg C., Aydogdu M., Buhles M., Dressler F., Eberl W., Haase R., Edler von Koch F., Feidicker S., Frambach T., Franz H.G.B., Guthmann F., Koch H.G., Seeger S., Oberhoff C., Pauker W., Petry K.U., Schild R.L., Tchirikov M., ... , Röhrig E., Mikolajczyk R.
(2019)
Cohort profile: The LoewenKIDS Study - life-course perspective on infections, the microbiome and the development of the immune system in early childhood
Int.J.Epidemiol.,
48
(4)
Author count: 12
Banda D.H., Perin P.M., Brown R.J.P., Todt D., Solodenko W., Hoffmeyer P., Sahu K.K., Houghton M., Meuleman P., Müller R., ... , Kirschning A., Pietschmann T.
(2019)
A central hydrophobic E1 region controls the pH range of hepatitis C virus membrane fusion and susceptibility to fusion inhibitors
J.Hepatol.,
70
(6)
Author count: 26
Khera T., Behrendt P., Bankwitz D., Brown R.J.P., Todt D., Doepke M., Khan A.G., Schulze K., Law J., Logan M., Hockman D., Wong J.A.J.-X., Dold L., Gonzalez-Motos V., Spengler U., Viejo-Borbolla A., Ströh L., Krey T., Tarr A.W., Steinmann E., Manns M.P., Klein F., Guzmán C.A., Marcotrigiano J., ... , Houghton M., Pietschmann T.
(2019)
Functional and immunogenic characterization of diverse HCV glycoprotein E2 variants
J.Hepatol.,
70
(4)
Author count: 18
Garcia-Nicolas O., V'kovski P., Vielle N.J., Ebert N., Züst R., Portmann J., Stalder H., Gaschen V., Vieyres G., Stoffel M., Schweizer M., Summerfield A., Engler O., Pietschmann T., Todt D., Alves M.P., ... , Thiel V., Pfaender S.
(2018)
The small compound inhibitor K22 displays broad antiviral activity against different members of the family Flaviviridae and offers potential as pan-viral inhibitor
Antimicrob.Agents Chemother.,
62
(11)
Author count: 11
Bruening J., Lasswitz L., Banse P., Kahl S., Marinach C., Vondran F.W., Kaderali L., Silvie O., Pietschmann T., ... , Meissner F., Gerold G.
(2018)
Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB
PLoS Pathog.,
14
(7)
Author count: 9
Banse P., Moeller R., Bruening J., Lasswitz L., Kahl S., Khan A.G., Marcotrigiano J., ... , Pietschmann T., Gerold G.
(2018)
CD81 Receptor Regions outside the Large Extracellular Loop Determine Hepatitis C Virus Entry into Hepatoma Cells
Viruses.,
10
(4)
Author count: 12
Bartenschlager R., Baumert T.F., Bukh J., Houghton M., Lemon S.M., Lindenbach B.D., Lohmann V., Moradpour D., Pietschmann T., Rice C.M., ... , Thimme R., Wakita T.
(2018)
Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: considerations for scientists and funding agencies
Virus Res.,
248
(March)
Author count: 12
Baier C., Haid S., Beilken A., Behnert A., Wetzke M., Brown R.J.P., Schmitt C., Ebadi E., Hansen G., Schulz T.F., ... , Pietschmann T., Bange F.C.
(2018)
Molecular characteristics and successful management of a respiratory syncytial virus outbreak among pediatric patients with hemato-oncological disease
Antimicrob.Resist.Infect.Control,
7
(1)
Author count: 17
Knegendorf L., Drave S.A., Dao Thi V, Debing Y., Brown R.J.P., Vondran F.W.R., Resner K., Friesland M., Khera T., Engelmann M., Bremer B., Wedemeyer H., Behrendt P., Neyts J., Pietschmann T., ... , Todt D., Steinmann E.
(2018)
Hepatitis E virus replication and interferon responses in human placental cells
Hepatol.Commun.,
2
(2)
Author count: 8
Riber C.F., Andersen A.H.F., Gajda P., Lovschall K.B., Dagnaes-Hansen F., Banda D.H., ... , Pietschmann T., Tolstrup M.
(2017)
Synthetic Polymer with a Structure-Driven Hepatic Deposition and Curative Pharmacological Activity in Hepatic Cells
ACS Macro Lett.,
6
(9)
Author count: 15
Behrendt P., Perin P., Menzel N., Banda D., Pfaender S., Alves M.P., Thiel V., Meulemann P., Colpitts C.C., Schang L.M., Vondran F.W.R., Anggakusuma, Manns M.P., ... , Steinmann E., Pietschmann T.
(2017)
Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry
Antiviral Res.,
147
(November)
Author count: 7
Weller R., Hueging K., Brown R.J.P., Todt D., Joecks S., ... , Vondran F.W.R., Pietschmann T.
(2017)
Hepatitis C virus strain-dependent usage of apolipoprotein E modulates assembly efficiency and specific infectivity of secreted virions
J.Virol.,
91
(18)
Author count: 3
Bartenschlager R., Cornberg M., Pietschmann T.
(2017)
[Personalized treatment of viral hepatitis of the present and the future : Hepatitis B, C, delta, and E]
Internist (Berl),
58
(7)
Author count: 12
Vasiliauskaite I., Owsianka A., England P., Khan A.G., Cole S., Bankwitz D., Foung S.K.H., Pietschmann T., Marcotrigiano J., Rey F.A., ... , Patel A.H., Krey T.
(2017)
Conformational Flexibility in the Immunoglobulin-Like Domain of the Hepatitis C Virus Glycoprotein E2
MBio.,
8
(3)
Author count: 17
Anggakusuma, Romero-Brey I., Berger C., Colpitts C.C., Boldanova T., Engelmann M., Todt D., Perin P.M., Behrendt P., Vondran F.W.R., Xu S., Goffinet C., Schang L.M., Heim M.H., Bartenschlager R., ... , Pietschmann T., Steinmann E.
(2015)
Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation
Hepatology,
62
(3)
Author count: 11
Bankwitz D., Doepke M., Hueging K., Weller R., Bruening J., Behrendt P., Lee J.Y., Vondran F.W.R., Manns M.P., ... , Bartenschlager R., Pietschmann T.
(2017)
Maturation of secreted HCV particles by incorporation of secreted apoE protects from antibodies by enhancing infectivity
J.Hepatol.,
67
(3)
Author count: 23
Pfaender S., Walter S., Grabski E., Todt D., Bruening J., Romero-Brey I., Gather T., Brown R.J., Hahn K., Puff C., Pfankuche V.M., Hansmann F., Postel A., Becher P., Thiel V., Kalinke U., Wagner B., Bartenschlager R., Baumgartner W., Feige K., Pietschmann T., ... , Cavalleri J.M., Steinmann E.
(2017)
Immune protection against reinfection with nonprimate hepacivirus
Proc.Natl.Acad.Sci U.S A,
114
(12)
Author count: 19
Siddharta A., Pfaender S., Vielle N.J., Dijkman R., Friesland M., Becker B., Yang J., Engelmann M., Todt D., Windisch M.P., Brill F.H., Steinmann J., Steinmann J., Becker S., Alves M.P., Pietschmann T., Eickmann M., ... , Thiel V., Steinmann E.
(2017)
Virucidal activity of WHO-recommended formulations against enveloped viruses including Zika, Ebola and emerging Coronaviruses
J Infect.Dis.,
215
(6)
Author count: 3
Gerold G., Bruening J., Pietschmann T.
(2016)
Decoding protein networks during virus entry by quantitative proteomics
Virus Res.,
218
Author count: 1
Pietschmann T.
(2017)
Clinically approved ion channel inhibitors close gates for hepatitis C virus and open doors for drug repurposing in infectious viral diseases
J.Virol.,
91
(2)
Author count: 16
Khera T., Todt D., Steinmann E., Pietschmann T., Brown R.J.P., Vercauteren K., Verhoye L., Farhoudi A., Meuleman P., Mcclure C.P., Bhuju S., Geffers R., Baumert T.F., Baumert T.F., ... , Baumert T.F., Pietschmann T.
(2017)
Tracking HCV protease population diversity during transmission and susceptibility of founder populations to antiviral therapy
Antiviral Res.,
139
Author count: 4
Gerold G., Bruening J., Weigel B., Pietschmann T.
(2017)
Protein interactions during the flavivirus and hepacivirus life cycle
Mol.Cell Proteomics,
16
(4)
Author count: 7
Anggakusuma, Brown R.J.P., Banda D.H., Todt D., Vieyres G., ... , Steinmann E., Pietschmann T.
(2016)
Hepacivirus NS3/4A proteases interfere with MAVS signaling in both their cognate animal hosts and humans: Implications for zoonotic transmission
J.Virol.,
90
(23)
Author count: 16
von Schaewen M., Dorner M., Hueging K., Foquet L., Gerges S., Hrebikova G., Heller B., Bitzegeio J., Doerrbecker J., Horwitz J.A., Gerold G., Suerbaum S., Rice C.M., Meuleman P., ... , Pietschmann T., Ploss A.
(2016)
Expanding the Host Range of Hepatitis C Virus through Viral Adaptation
MBio.,
7
(6)
Author count: 14
Xu S., Ducroux A., Ponnurangam A., Vieyres G., Franz S., Musken M., Zillinger T., Malassa A., Ewald E., Hornung V., Barchet W., Häußler S., ... , Pietschmann T., Goffinet C.
(2016)
cGAS-Mediated Innate Immunity Spreads Intercellularly through HIV-1 Env-Induced Membrane Fusion Sites
Cell Host.Microbe,
20
(4)
Author count: 2
Bankwitz D., Pietschmann T.
(2016)
Hepatitis C virus plays hide and seek with neutralizing antibodies
Hepatology,
64
(6)
Author count: 7
Weller R., Todt D., Engelmann M., Friesland M., Wedemeyer H., ... , Pietschmann T., Steinmann E.
(2016)
Apolipoprotein E polymorphisms and their protective effect on Hepatitis E virus replication
Hepatology,
64
(6)
Author count: 8
Pfaender S., Grabski E., Detje C.N., Riebesehl N., Lienenklaus S., Steinmann E., ... , Kalinke U., Pietschmann T.
(2016)
Hepatitis C Virus Stimulates Murine CD8a[alpha]-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner
PLoS Pathog.,
12
(7)
Author count: 8
Vieyres G., Welsch K., Gerold G., Gentzsch J., Kahl S., Vondran F.W., ... , Kaderali L., Pietschmann T.
(2016)
ABHD5/CGI-58, the Chanarin-Dorfman Syndrome Protein, Mobilises Lipid Stores for Hepatitis C Virus Production
PLoS Pathog.,
12
(4)
Author count: 14
Walter S., Bollenbach A., Doerrbecker J., Pfaender S., Brown R.J., Vieyres G., Scott C., Foster R., Kumar A., Zitzmann N., Griffin S., Penin F., ... , Pietschmann T., Steinmann E.
(2016)
Ion-channel function and cross-species determinants in viral assembly of nonprimate hepacivirus p7
J Virol.,
90
(10)
Author count: 12
Todt D., Francois C., Anggakusuma, Behrendt P., Engelmann M., Knegendorf L., Vieyres G., Wedemeyer H., Hartmann R., Pietschmann T., ... , Duverlie G., Steinmann E.
(2016)
Antiviral activity of different interferon (sub-) types against hepatitis E virus replication
Antimicrob.Agents Chemother.,
60
(4)
Author count: 5
Haid S., Grethe C., Bankwitz D., Grunwald T., Pietschmann T.
(2015)
Identification of a human respiratory syncytial virus (hRSV) cell entry inhibitor by using a novel lentiviral pseudotype (hRSVpp) system
J Virol.,
90
(6)
Author count: 13
Walker A., Skibbe K., Steinmann E., Pfaender S., Kuntzen T., Megger D.A., Groten S., Sitek B., Lauer G.M., Kim A.Y., Pietschmann T., ... , Allen T.M., Timm J.
(2015)
Distinct escape pathway by HCV genotype 1a from a dominant CD8+ T cell response by selection of altered epitope processing
J Virol.,
90
Author count: 18
Vercauteren K., Brown R.J., Mesalam A.A., Doerrbecker J., Bhuju S., Geffers R., Van Den Eede N., Mcclure C.P., Troise F., Verhoye L., Baumert T., Farhoudi A., Cortese R., Ball J.K., Leroux-Roels G., Pietschmann T., ... , Nicosia A., Meuleman P.
(2015)
Targeting a host-cell entry factor barricades antiviral-resistant HCV variants from on-therapy breakthrough in human-liver mice
GUT,
65
Author count: 13
Gerold G., Meissner F., Bruening J., Welsch K., Perin P.M., Baumert T.F., Vondran F.W., Kaderali L., Marcotrigiano J., Khan A.G., Mann M., ... , Rice C.M., Pietschmann T.
(2015)
Quantitative Proteomics Identifies Serum Response Factor Binding Protein 1 as a Host Factor for Hepatitis C Virus Entry
Cell Rep.,
12
(5)
Author count: 12
Hueging K., Weller R., Doepke M., Vieyres G., Todt D., Wolk B., Vondran F.W., Geffers R., Lauber C., Kaderali L., ... , Penin F., Pietschmann T.
(2015)
Several Human Liver Cell Expressed Apolipoproteins Complement HCV Virus Production with Varying Efficacy Conferring Differential Specific Infectivity to Released Viruses
PLoS ONE,
10
(7)
Author count: 24
Perin P.M., Haid S., Brown R.J., Doerrbecker J., Schulze K., Zeilinger C., von Schaewen M., Heller B., Vercauteren K., Luxenburger E., Baktash Y.M., Vondran F.W., Speerstra S., Awadh A., Mukhtarov F., Schang L.M., Kirschning A., Müller R., Guzmán C.A., Kaderali L., Randall G., Meuleman P., ... , Ploss A., Pietschmann T.
(2016)
Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1
Hepatology,
63
Author count: 30
Lump E., Castellano L.M., Meier C., Seeliger J., Erwin N., Sperlich B., Sturzel C.M., Usmani S., Hammond R.M., von Einem J., Gerold G., Kreppel F., Bravo-Rodriguez K., Pietschmann T., Holmes V.M., Palesch D., Zirafi O., Weissman D., Sowislok A., Wettig B., Heid C., Kirchhoff F., Weil T., Klarner F.G., Schrader T., Bitan G., Sanchez-Garcia E., Winter R., ... , Shorter J., Munch J.
(2015)
A molecular tweezer antagonizes seminal amyloids and HIV infection
Elife.,
4
Author count: 7
Tarr A.W., Khera T., Hueging K., Sheldon J., Steinmann E., ... , Pietschmann T., Brown R.J.
(2015)
Genetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine Design
Viruses.,
7
(7)
Author count: 13
Lauber C., Vieyres G., Terczynska-Dyla E., Anggakusuma, Dijkman R., Gad H.H., Akhtar H., Geffers R., Vondran F.W., Thiel V., Kaderali L., ... , Pietschmann T., Hartmann R.
(2015)
Transcriptome analysis reveals a classical interferon signature induced by IFNlambda4 in human primary cells
Genes Immun.,
16
(6)
Author count: 15
Koutsoudakis G., Romero-Brey I., Berger C., Perez-Vilaro G., Perin P.M., Vondran F.W., Kalesse M., Harmrolfs K., Müller R., Martinez J.P., Pietschmann T., Bartenschlager R., Bronstrup M., ... , Meyerhans A., Diez J.
(2015)
Soraphen A: a broad-spectrum antiviral natural product with potent anti-hepatitis C virus activity
J Hepatol.,
63
(4)
Author count: 16
Pfaender S., Walter S., Todt D., Behrendt P., Doerrbecker J., Woelk B., Engelmann M., Gravemann U., Seltsam A., Steinmann J., Burbelo P.D., Klawonn F., Feige K., Pietschmann T., ... , Cavalleri J.M., Steinmann E.
(2015)
Assessment of cross-species transmission of hepatitis C-related non-primate hepacivirus in a population of humans at high risk of exposure
J Gen.Virol.,
96
(9)
Author count: 12
Anggakusuma, Frentzen A., Gürlevik E., Yuan Q., Steinmann E., Ott M., Staeheli P., Schmid-Burgk J., Schmidt T., Hornung V., ... , Kuehnel F., Pietschmann T.
(2015)
Control of hepatitis C virus replication in mouse liver-derived cells by MAVS-dependent production of type I and type III interferons
J.Virol.,
89
(7)
Author count: 14
Vercauteren K., Van Den Eede N., Mesalam A.A., Belouzard S., Catanese M.T., Bankwitz D., Wong-Staal F., Cortese R., Dubuisson J., Rice C.M., Pietschmann T., Leroux-Roels G., ... , Nicosia A., Meuleman P.
(2014)
Successful anti-scavenger receptor class B type I (SR-BI) monoclonal antibody therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents
Hepatology,
60
(5)
Author count: 8
Pfaender S., Brinkmann J., Todt D., Riebesehl N., Steinmann J., Steinmann J., ... , Pietschmann T., Steinmann E.
(2015)
Mechanisms of methods for hepatitis C virus inactivation
Appl.Environ.Microbiol.,
81
(5)
Author count: 15
Hedenstierna M., Weiland O., Brass A., Bankwitz D., Behrendt P., Uhnoo I., Aleman S., Cardell K., Fryden A., Norkrans G., Eilard A., Glaumann H., Pietschmann T., ... , Sällberg M., Brenndörfer E.D.
(2015)
Long-term follow-up of successful hepatitis C virus therapy: Waning immune responses and disappearance of liver disease are consistent with cure
Aliment.Pharmacol.Ther.,
41
(6)
Author count: 8
Grabski E., Wappler I., Pfaender S., Steinmann E., Haid S., Dzionek A., ... , Pietschmann T., Kalinke U.
(2014)
Efficient virus assembly, but not infectivity, determines the magnitude of hepatitis C virus induced interferon-alpha responses of plasmacytoid dendritic cells
Journal of Virology,
89
Author count: 17
Pfaender S., Cavalleri J.M., Walter S., Doerrbecker J., Campana B., Brown R.J., Burbelo P.D., Postel A., Hahn K., Kusuma A., Riebesehl N., Baumgartner W., Becher P., Heim M.H., Pietschmann T., ... , Feige K., Steinmann E.
(2014)
Clinical course of infection and viral tissue tropism of hepatitis C virus-like non-primate hepaciviruses in horses
Hepatology,
61
(2)
Author count: 13
Bankwitz D., Vieyres G., Hueging K., Bitzegeio J., Doepke M., Chhatwal P., Haid S., Catanese M.T., Zeisel M.B., Nicosia A., Baumert T.F., ... , Kaderali L., Pietschmann Thomas
(2014)
Role of the hypervariable region 1 (HVR1) for the interplay of hepatitis C virus with entry factors and lipoproteins
Journal of Virologie,
88
Author count: 1
Pietschmann Thomas
(2014)
In sero veritas: What serum markers teach us about HCV infection of primary human hepatocytes
GUT,
63
(9)
Author count: 10
Irving W.L., Rupp D., Mcclure C.P., Than L.M., Titman A., Ball J.K., Steinmann Eike, Bartenschlager R., ... , Pietschmann Thomas, Brown Richard J.P.
(2014)
Development of a high-throughput pyrosequencing assay for monitoring temporal evolution and resistance associated variant emergence in the Hepatitis C virus protease coding-region
Antiviral Research,
110
(1)
Author count: 2
Gerold Gisa, Pietschmann Thomas
(2014)
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
Digestive Diseases,
32
(5)
Author count: 14
Lange M., Fiedler M., Bankwitz D., Osburn W., Viazov S., Brovko O., Zekri A.R., Khudyakov Y., Nassal M., Pumpens P., Pietschmann Thomas, Timm J., ... , Roggendorf M., Walker A.
(2014)
Hepatitis C virus hypervariable region 1 variants presented on hepatitis B virus capsid-like particles induce cross-neutralizing antibodies
PLoS ONE,
9
(7)
Author count: 12
Doerrbecker J., Friesland M., Riebesehl N., Ginkel C., Behrendt P., Brown R.J., Ciesek S., Wedemeyer H., Sarrazin C., Kaderali L., ... , Pietschmann T., Steinmann E.
(2014)
Incorporation of primary patient-derived glycoproteins into authentic infectious hepatitis C virus particles
Hepatology,
60
Author count: 4
Pfaender S., Brown R.J., Pietschmann T., Steinmann E.
(2014)
Natural reservoirs for homologs of hepatitis C virus
Emerging Microbes and Infections,
3
Author count: 3
Vieyres G., Dubuisson J., Pietschmann Thomas
(2014)
Incorporation of hepatitis C virus e1 and e2 glycoproteins: the keystones on a peculiar virion
Viruses,
6
(3)
Author count: 22
Brown R.J.P., Koutsoudakisu G., Urbanowicz R.A., Mirza D., Ginkel C., Riebesehl N., Calland N., Albecka A., Price L., Hudson N., Descamps V., Backx M., Patrick McClure C., Duverlie G., Pecheur E.I., Dubuisson J., Perez-Del-Pulgar S., Forns X., Steinmann Eike, Tarr A.W., ... , Pietschmann Thomas, Ball J.K.
(2014)
Analysis of serine codon conservation reveals diverse phenotypic constraints on hepatitis C virus glycoprotein evolution
Journal of Virology,
88
(1)
Author count: 2
Steinmann Eike, Pietschmann Thomas
(2013)
Cell culture systems for hepatitis C virus
Current Topics in Microbiology and Immunology,
369
Author count: 2
Gerold G., Pietschmann Thomas
(2013)
A circuit of paracrine signals between liver sinusoid endothelial cells and hepatocytes regulates hepatitis C virus replication
Hepatology,
59
Author count: 2
Gerold Gisa, Pietschmann Thomas
(2013)
Hepatitis C virus NS5B polymerase primes innate immune signaling
Hepatology,
57
(3)
Author count: 4
Steinmann J., Buer J., Pietschmann Thomas, Steinmann Eike
(2013)
Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea
British Journal of Pharmacology,
168
(5)
Author count: 10
Hamming O.J., Terczynska-Dyla E., Vieyres G., Dijkman R., Jorgensen S.E., Akhtar H., Siupka P., Pietschmann T., ... , Thiel V., Hartmann R.
(2013)
Interferon lambda 4 signals via the IFNambda receptor to regulate antiviral activity against HCV and coronaviruses
Embo Journal,
32
(23)
Author count: 11
Hüging K., Döpke M., Vieyres G., Bankwitz D., Frentzen A., Dörrbecker J., Gumz F., Haid S., Wölk B., ... , Kaderali L., Pietschmann T.
(2013)
Apolipoprotein E co-determines tissue-tropism of hepatitis C virus and it is crucial for viral cell-to-cell transmission by contributing to a post-envelopment step of assembly
Journal of Virology,
88
(3)
Author count: 14
Pfaender S., Heyden J., Friesland M., Ciesek S., Ejaz A., Steinmann J., Steinmann J., Malarski A., Stoiber H., Tsiavaliaris G., Bader W., Jahreis G., ... , Pietschmann T., Steinmann E.
(2013)
Inactivation of Hepatitis C Virus Infectivity by Human Breast Milk
Journal of Infectious Diseases,
208
(12)
Author count: 11
Steinmann Eike, Doerrbecker Juliane, Friesland Martina, Riebesehl Nina, Ginkel Corinne, Hillung Julia, Gentzsch Juliane, Lauber C., Brown Richard, ... , Frentzen Anne, Pietschmann Tim
(2013)
Characterization of hepatitis C virus intra- and inter-genotypic chimeras reveals a role of the glycoproteins in virus envelopment
Journal of Virology,
52
Author count: 11
Behrendt P., Doerrbecker J., Riebesehl N., Wilhelm C., Ciesek S., Erichsen T.J., Steinmann J., Ott M., Manns M.P., ... , Pietschmann T., Steinmann E.
(2013)
Stability and transmission of hepatitis C virus in different anesthetic agents
American Journal of Infection Control,
41
(10)
Author count: 17
Zahid M.N., Turek M., Xiao F., Dao Thi V, Guerin M., Fofana I., Bachellier P., Thompson J., Delang L., Neyts J., Bankwitz D., Pietschmann Thomas*, Dreux M., Cosset F.L., Grunert F., ... , Baumert T.F., Zeisel M.B.
(2013)
The postbinding activity of scavenger receptor class B type I mediates initiation of hepatitis C virus infection and viral dissemination
Hepatology,
57
(2)
Author count: 7
Steinmann E., Gravemann U., Friesland M., Doerrbecker J., Muller T.H., ... , Pietschmann Thomas*, Seltsam A.
(2013)
Two pathogen reduction technologies-methylene blue plus light and shortwave ultraviolet light-effectively inactivate hepatitis C virus in blood products
Transfusion,
53
(5)
Author count: 13
Nandakumar R., Finsterbusch K., Lipps C., Neumann B., Grashoff M., Nair S., Hochnadel I., Lienenklaus S., Wappler I., Steinmann E., Hauser H., ... , Pietschmann T., Kröger A.
(2013)
Hepatitis C Virus Replication in Mouse Cells is Restricted by IFN-Dependent and -Independent Mechanisms
Gastroenterology,
145
(6)
Author count: 16
Anggakusuma, Colpitts C.C., Schang L.M., Rachmawati H., Frentzen A., Pfaender S., Behrendt P., Brown R.J., Bankwitz D., Steinmann J., Ott M., Meuleman P., Rice C.M., Ploss A., ... , Pietschmann T., Steinmann E.
(2013)
Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells
GUT,
63
Author count: 14
Frentzen Anne, Kusuma Angga, Guerlevik E., Hueging Kathrin, Knocke S., Ginkel Corinne, Brown Richard J.P., Heim M., Dill M.T., Kröger Andrea, Kalinke Ulrich, Kaderali L., ... , Kuehnel F., Pietschmann Thomas
(2013)
Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells
Hepatology
Author count: 6
Haid S., Grethe C., Dill M.T., Heim M., Kaderali L., Pietschmann T.
(2013)
Isolate-dependent use of Claudins for cell entry by hepatitis C virus
Hepatology,
59
(1)
Author count: 10
Doerrbecker J., Meuleman P., Kang J., Riebesehl N., Wilhelm C., Friesland M., Pfaender S., Steinmann J., ... , Pietschmann T., Steinmann E.
(2013)
Thermostability of seven hepatitis C virus genotypes in vitro and in vivo
Journal of Viral Hepatitis,
20
(7)
Author count: 10
Gentzsch J., Brohm C., Steinmann Eike, Friesland M., Menzel N., Vieyres G., Perin P.M., Frentzen Anne, ... , Kaderali L., Pietschmann Thomas
(2013)
Hepatitis C Virus p7 is Critical for Capsid Assembly and Envelopment
PLoS Pathogens,
9
(5)
Author count: 13
Westhaus S., Bankwitz D., Ernst S., Rohrmann K., Wappler I., Agne C., Luchtefeld M., Schieffer B., Sarrazin C., Manns M.P., Pietschmann T., ... , Ciesek S., von Hahn T.
(2013)
Characterization of the inhibition of hepatitis C virus entry by In vitro-generated and patient-derived oxidized low-density lipoprotein
Hepatology,
57
(5)
Author count: 2
Vieyres G., Pietschmann Thomas
(2013)
Entry and replication of recombinant hepatitis C viruses in cell culture
Methods,
59
(2)
Author count: 21
Fofana I., Fafi-Kremer S., Carolla P., Fauvelle C., Zahid M.N., Turek M., Heydmann L., Cury K., Hayer J., Combet C., Cosset F.L., Pietschmann Thomas*, Hiet M.S., Bartenschlager R., Habersetzer F., Doffoel M., Keck Z.Y., Foung S.K., Zeisel M.B., ... , Stoll-Keller F., Baumert T.F.
(2012)
Mutations that alter use of hepatitis C virus cell entry factors mediate escape from neutralizing antibodies1
Gastroenterology,
143
(1)
Author count: 9
Doerrbecker J., Behrendt P., Mateu-Gelabert P., Ciesek S., Riebesehl N., Wilhelm C., Steinmann J.*, ... , Pietschmann Thomas*, Steinmann E.*
(2013)
Transmission of hepatitis C virus among people who inject drugs: viral stability and association with drug preparation equipment
Journal of Infectious Diseases,
207
(2)
Author count: 8
Vieyres G., Brohm C., Friesland M., Gentzsch J., Wolk B., Roingeard P., ... , Steinmann E., Pietschmann Thomas*
(2013)
Subcellular Localization and Function of an Epitope-Tagged p7 Viroporin in Hepatitis C Virus-Producing Cells
Journal of Virology,
87
(3)
Author count: 10
Kugler J., Schmelz S., Gentzsch J., Haid S., Pollmann E., van den Heuvel Joop, Franke R., Pietschmann Thomas, ... , Heinz Dirk W., Collins J.
(2012)
High Affinity Peptide Inhibitors of the Hepatitis C Virus NS3-4A Protease Refractory to Common Resistant Mutants
Journal of Biological Chemistry,
287
(46)
Author count: 5
Frentzen A., Hueging K., Bitzegeio J., Pietschmann Thomas*, Steinmann E.
(2012)
Two methods of heterokaryon formation to discover HCV restriction factors2
Journal of Visualized Experiments
(65)
Author count: 14
Ejaz A., Steinmann E., Bánki Z., Anggakusuma, Khalid S., Lengauer S., Wilhelm C., Zoller H., Schloegl A., Steinmann J., Grabski E., Kleines M., ... , Pietschmann Thomas*, Stoiber H.
(2012)
Specific Acquisition of Functional CD59 but Not CD46 or CD55 by Hepatitis C Virus
PLoS ONE,
7
(9)
Author count: 10
Menzel N., Fischl W., Hueging K., Bankwitz D., Frentzen A., Haid S., Gentzsch J., Kaderali L., ... , Bartenschlager R., Pietschmann Thomas*
(2012)
MAP-Kinase Regulated Cytosolic Phospholipase A2 Activity Is Essential for Production of Infectious Hepatitis C Virus Particles1
PLoS Pathogens,
8
(7)
Author count: 9
Sandmann L., Wilson M., Back D., Wedemeyer H., Manns M.P., Steinmann E., Pietschmann Thomas*, ... , von Hahn T., Ciesek S.
(2012)
Antiretroviral drugs do not facilitate hepatitis C virus (HCV) infection in vitro
Antiviral Research,
96
(1)
Author count: 6
Barbier J., Wegner J., Benson S., Gentzsch J., Pietschmann Thomas*, Kirschning A.
(2012)
Total synthesis of a noricumazole a library and evaluation of HCV inhibition1
Chemistry,
18
(29)
Author count: 18
von Hahn T., Schiene-Fischer C., Van N.D., Pfaender S., Karavul B., Steinmann E., Potthoff A., Strassburg C., Hamdi N., Abdelaziz A.I., Sarrazin C., Muller T., Berg T., Trepo E., Wedemeyer H., Manns M.P., ... , Pietschmann Thomas*, Ciesek S.
(2012)
Hepatocytes that express variants of cyclophilin a are resistant to HCV infection and replication1
Gastroenterology,
143
(2)
Author count: 14
Stegmann K.A., Bjorkstrom N.K., Ciesek S., Lunemann S., Jaroszewicz J., Wiegand J., Malinski P., Dustin L.B., Rice C.M., Manns M.P., Pietschmann T., Cornberg M., ... , Ljunggren H.G., Wedemeyer H.
(2012)
Interferon a[alpha]-stimulated natural killer cells from patients with acute hepatitis C virus (HCV) infection recognize HCV-infected and uninfected hepatoma cells via DNAX accessory molecule-11
Journal of Infectious Diseases,
205
(9)
Author count: 5
Steinmann E., Ciesek S., Friesland M., Erichsen T.J., Pietschmann Thomas*
(2011)
Prolonged survival of hepatitis C virus in the anesthetic propofol2
Clinical Infectious Diseases,
53
(9)
Author count: 23
Haybaeck J., Zeller N., Wolf M.J., Weber A., Wagner U., Kurrer M.O., Bremer J., Iezzi G., Graf R., Clavien P.A., Thimme R., Blum H., Nedospasov S.A., Zatloukal K., Ramzan M., Ciesek S., Pietschmann Thomas*, Marche P.N., Karin M., Kopf M., Browning J.L., ... , Aguzzi A., Heikenwalder M.
(2009)
Erratum: A lymphotoxin-driven pathway to hepatocellular carcinoma3
Cancer Cell,
16
(5)
Author count: 7
Chhatwal P., Bankwitz D., Grentzsch J., Frenzen A., Schult Ph., ... , Lohmann V., Pietschmann Thomas*
(2012)
Bile Acids Specifically Increase Hepatitis C Virus RNA-Replication
PLoS ONE,
7
(4)
Author count: 19
Haid S., Novodomska A., Gentzsch J., Grethe C., Geuenich S., Bankwitz D., Chhatwal P., Jannack B., Hennebelle T., Bailleul F., Keppler O.T., Ponisch M., Bartenschlager R., Hernandez C., Lemasson M., Rosenberg A., Wong-Staal F., ... , vioud-Charvet E., Pietschmann Thomas*
(2012)
A Plant-Derived Flavonoid Inhibits Entry of All HCV Genotypes into Human Hepatocytes
Gastroenterology,
143
(1)
Author count: 13
Ruhl M., Chhatwal P., Strathmann H., Kuntzen T., Bankwitz D., Skibbe K., Walker A., Heinemann F.M., Horn P.A., Allen T.M., Hoffmann D., ... , Pietschmann Thomas*, Timm J.
(2012)
Escape from a dominant HLA-B*15-restricted CD8+ T cell response against hepatitis C virus requires compensatory mutations outside the epitope1
Journal of Virology,
86
(2)
Author count: 12
Ciesek S., von Hahn T., Colpitts C.C., Schang L.M., Friesland M., Steinmann J., Manns M.P., Ott M., Wedemeyer H., Meuleman P., ... , Pietschmann Thomas*, Steinmann E.
(2011)
The green tea polyphenol, epigallocatechin-3-gallate, inhibits hepatitis C virus entry
Hepatology,
54
(6)
Author count: 9
Doerrbecker J., Friesland M., Ciesek S., Erichsen T.J., Mateu-Gelabert P., Steinmann J., Steinmann J., ... , Pietschmann Thomas*, Steinmann E.
(2011)
Inactivation and survival of hepatitis C virus on inanimate surfaces
Journal of Infectious Diseases,
204
(12)
Author count: 12
von Hahn T., Schulze A., Wust I.C., Heidrich B., Becker T., Steinmann E., Helfritz F.A., Rohrmann K., Urban S., Manns M.P., ... , Pietschmann Thomas*, Ciesek S.
(2011)
The novel immunosuppressive protein kinase C inhibitor sotrastaurin has no pro-viral effects on the replication cycle of hepatitits B or C virus
PLoS ONE,
6
(9)
Author count: 2
Steinmann E., Pietschmann Thomas*
(2010)
Hepatitis C virus P7 - a viroporin crucial for virus assembly and an emerging target for antiviral therapy
Viruses,
285
(41)
Author count: 13
Ciesek S., Westhaus S., Wicht M., Wappler I., Henschen S., Sarrazin C., Hamdi N., Abdelaziz A.I., Strassburg C.P., Wedemeyer H., Manns M.P., ... , Pietschmann Thomas*, von Hahn T.
(2011)
Impact of intra- and interspecies variation of occludin on its function as coreceptor for authentic hepatitis C virus particles
Journal of Virology,
85
(15)
Author count: 13
Frentzen A., Huging K., Bitzegeio J., Friesland M., Haid S., Gentzsch J., Hoffmann M., Lindemann D., Zimmer G., Zielecki F., Weber F., ... , Steinmann E., Pietschmann Thomas*
(2011)
Completion of hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines
PLoS Pathogens,
7
(4)
Author count: 26
Lupberger J., Zeisel M.B., Xiao F., Thumann C., Fofana I., Zona L., Davis C., Mee C.J., Turek M., Gorke S., Royer C., Fischer B., Zahid M.N., Lavillette D., Fresquet J., Cosset F.L., Rothenberg S.M., Pietschmann Thomas*, Patel A.H., Pessaux P., Doffoel M., Raffelsberger W., Poch O., McKeating J.A., ... , Brino L., Baumert T.F.
(2011)
EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy
Nature medicine,
17
(5)
Author count: 8
Gentzsch J., Hinkelmann B., Kaderali L., Irschik Herbert*, Jansen Rolf*, Sasse Florenz*, ... , Frank Ronald*, Pietschmann Thomas*
(2011)
Hepatitis C virus complete life cycle screen for identification of small molecules with pro- or antiviral activity
Antiviral Research,
89
(2)
Author count: 10
Burgel B., Friesland M., Koch A., Manns M.P., Wedemeyer H., Weissenborn K., Schulz-Schaeffer W.J., Pietschmann Thomas*, ... , Steinmann E., Ciesek S.
(2011)
Hepatitis C virus enters human peripheral neuroblastoma cells - evidence for extra-hepatic cells sustaining hepatitis C virus penetration
Journal of Viral Hepatitis,
18
(8)
Author count: 11
Bitzegeio J., Bankwitz D., Hueging K., Haid S., Brohm C., Zeisel M.B., Herrmann E., Iken M., Ott M., ... , Baumert T.F., Pietschmann Thomas*
(2010)
Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors
PLoS Pathogens,
6
Author count: 14
Montserret R., Saint N., Vanbelle C., Salvay A.G., Simorre J.P., Ebel C., Sapay N., Renisio J.G., Bockmann A., Steinmann E., Pietschmann Thomas*, Dubuisson J., ... , Chipot C., Penin F.
(2010)
NMR structure and ion channel activity of the p7 protein from hepatitis C virus
Journal of Biological Chemistry,
285
(41)
Author count: 4
von Hahn T., Steinmann E., Ciesek S., Pietschmann Thomas*
(2010)
Know your enemy: translating insights about the molecular biology of hepatitis C virus into novel therapeutic approaches
Expert Review of Gastroenterology and Hepatology,
4
(1)
Author count: 8
Lemon S.M., McKeating J.A., Pietschmann Thomas*, Frick D.N., Glenn J.S., Tellinghuisen T.L., ... , Symons J., Furman P.A.
(2010)
Development of novel therapies for hepatitis C
Antiviral Research,
86
(1)
Author count: 9
Ciesek S., Steinmann E., Iken M., Ott M., Helfritz F.A., Wappler I., Manns M.P., ... , Wedemeyer H., Pietschmann Thomas*
(2010)
Glucocorticosteroids increase cell entry by hepatitis C virus
Gastroenterology,
138
(5)
Author count: 12
Bankwitz D., Steinmann E., Bitzegeio J., Ciesek S., Friesland M., Herrmann E., Zeisel M.B., Baumert T.F., Keck Z.Y., Foung S.K., ... , Pecheur E.I., Pietschmann Thomas*
(2010)
Hepatitis C virus hypervariable region 1 modulates receptor interactions, conceals the CD81 binding site, and protects conserved neutralizing epitopes
Journal of Virology,
84
(11)
Author count: 9
Ciesek S., Friesland M., Steinmann J., Becker B., Wedemeyer H., Manns M.P., Steinmann J., ... , Pietschmann Thomas*, Steinmann E.
(2010)
How stable is the hepatitis C virus (HCV)? Environmental stability of HCV and its susceptibility to chemical biocides
Journal of Infectious Diseases,
201
(12)
Author count: 19
Stegmann K.A., Björkström N.K., Liermann H., Ciesek S., Riese P., Wiegand J., Hadem J., Suneetha P.V., Jaroszewicz J., Wang C., Schlaphoff V., Fytili P., Cornberg M., Manns M.P., Geffers R., Pietschmann T., Guzmán C.A., ... , Ljunggren H.-G., Wedemeyer H.
(2010)
Interf alpha-induced TRAIL on human NK cells is associated with control of hepatitis C virus infection
Gastroenterology,
138
(5)
Author count: 8
Brohm C., Steinmann E., Friesland M., Lorenz I.C., Patel A., Penin F., ... , Bartenschlager R., Pietschmann Thomas*
(2009)
Characterization of determinants important for hepatitis C virus p7 function in morphogenesis by using trans-complementation
Journal of Virology,
83
(22)
Author count: 4
Haid S., Windisch M.P., Bartenschlager R., Pietschmann Thomas*
(2010)
Mouse-specific residues of claudin-1 limit hepatitis C virus genotype 2a infection in a human hepatocyte cell line
Journal of Virology,
84
(2)
Author count: 8
Steinmann J., Becker B., Bischoff B., Paulmann D., Friesland M., Pietschmann Thomas*, ... , Steinmann J., Steinmann E.
(2009)
Virucidal activity of 2 alcohol-based formulations proposed as hand rubs by the World Health Organization
American Journal of Infection Control,
38
(1)
Author count: 10
Ciesek S., Steinmann E., Wedemeyer H., Manns M.P., Neyts J., Tautz N., Madan V., Bartenschlager R., ... , von Hahn T., Pietschmann Thomas*
(2009)
Cyclosporine A inhibits hepatitis C virus nonstructural protein 2 through cyclophilin A
Hepatology,
50
(5)
Author count: 23
Haybaeck J., Zeller N., Wolf M.J., Weber A., Wagner U., Kurrer M.O., Bremer J., Iezzi G., Graf R., Clavien P.A., Thimme R., Blum H., Nedospasov S.A., Zatloukal K., Ramzan M., Ciesek S., Pietschmann Thomas*, Marche P.N., Karin M., Kopf M., Browning J.L., ... , Aguzzi A., Heikenwalder M.
(2009)
A lymphotoxin-driven pathway to hepatocellular carcinoma
Cancer Cell,
16
(4)
Author count: 7
Schaller T., Appel N., Koutsoudakis G., Kallis S., Lohmann V., ... , Pietschmann Thomas*, Bartenschlager R.
(2007)
Analysis of hepatitis C virus superinfection exclusion by using novel fluorochrome gene-tagged viral genomes
Journal of Virology,
81
(9)
Author count: 7
Steinmann E., Whitfield T., Kallis S., Dwek R.A., Zitzmann N., ... , Pietschmann Thomas*, Bartenschlager R.
(2007)
Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus
Hepatology,
46
(2)
Author count: 1
Pietschmann Thomas*
(2009)
Full-length infectious HCV chimeras
Methods in Molecular Biology,
510
Author count: 11
Witteveldt J., Evans M.J., Bitzegeio J., Koutsoudakis G., Owsianka A.M., Angus A.G., Keck Z.Y., Foung S.K., Pietschmann Thomas*, ... , Rice C.M., Patel A.H.
(2009)
CD81 is dispensable for hepatitis C virus cell-to-cell transmission in hepatoma cells
Journal of General Virology,
90
(Pt 1)
Author count: 10
Pietschmann Thomas*, Zayas M., Meuleman P., Long G., Appel N., Koutsoudakis G., Kallis S., Leroux-Roels G., ... , Lohmann V., Bartenschlager R.
(2009)
Production of infectious genotype 1b virus particles in cell culture and impairment by replication enhancing mutations
PLoS Pathogens,
5
(6)
Author count: 3
Haid S., Pietschmann Thomas*., Pecheur E.I.
(2009)
Low pH-dependent Hepatitis C Virus Membrane Fusion Depends on E2 Integrity, Target Lipid Composition, and Density of Virus Particles
Journal of Biological Chemistry,
284
(26)
Author count: 1
Pietschmann Thomas*
(2009)
Virology: Final entry key for hepatitis C
Nature,
457
(7231)
Author count: 1
Pietschmann Thomas*
(2008)
Regulation of hepatitis C virus replication by microRNAs
Journal of Hepatology,
50
(3)
Author count: 10
Jirasko V., Montserret R., Appel N., Janvier A., Eustachi L., Brohm C., Steinmann E., Pietschmann Thomas*, ... , Penin F., Bartenschlager R.
(2008)
Structural and functional characterization of nonstructural protein 2 for its role in hepatitis C virus assembly
Journal of Biological Chemistry,
283
(42)
Author count: 5
Steinmann E., Brohm C., Kallis S., Bartenschlager R., Pietschmann Thomas*
(2008)
Efficient trans-encapsidation of hepatitis C virus RNAs into infectious virus-like particles
Journal of Virology,
82
(14)
Author count: 3
Pietschmann Thomas*, Steinmann E., Ciesek S.
(2008)
[Hepatitis C virus cell culture models--new perspectives for research and clinic]
Deutsche Medizinische Wochenschrift,
133
(30)
Author count: 5
Ciesek S., Steinmann E., Manns M.P., Wedemeyer H., Pietschmann Thomas*
(2008)
The suppressive effect that myriocin has on hepatitis C virus RNA replication is independent of inhibition of serine palmitoyl transferase
Journal of Infectious Diseases,
198
(7)
Author count: 6
Steinmann E., Penin F., Kallis S., Patel A.H., Bartenschlager R., Pietschmann Thomas*
(2007)
Hepatitis C virus p7 protein is crucial for assembly and release of infectious virions
PLoS Pathogens,
3
(7)
Author count: 18
Zeisel M.B., Koutsoudakis G., Schnober E.K., Haberstroh A., Blum H.E., Cosset F.L., Wakita T., Jaeck D., Doffoel M., Royer C., Soulier E., Schvoerer E., Schuster C., Stoll-Keller F., Bartenschlager R., Pietschmann Thomas*, ... , Barth H., Baumert T.F.
(2007)
Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81
Hepatology,
46
(6)