Prof. Dr. Theresia Stradal

Prof. Dr. Theresia Stradal
Forschungsgruppenleiterin

Theresia Stradal studierte Biologie an der Paris-Lodron-Universität zu Salzburg in Österreich, an der sie im Jahr 2000 am Institut für Molekularbiologie promovierte. Anschließend arbeitete sie für vier Jahre als Postdoc in der Abteilung Zellbiologie bei der Gesellschaft für Biotechnologische Forschung (heute: Helmholtz-Zentrum für Infektionsforschung, HZI) in Braunschweig.

Ab 2005 war sie dort als Forschungsgruppenleiterin tätig, bis sie 2009 von der Westfälischen Wilhelms Universität Münster zur Professorin (W2) berufen wurde und zum dortigen Institut für Molekulare Zellbiologie wechselte. 2014 kehrte sie nach Braunschweig zurück, wo sie eine W3-Professur am Institut für Zoologie der Technischen Universität Braunschweig annahm.

Zeitgleich wurde Theresia Stradal Leiterin der Abteilung Zellbiologie am HZI. Hier forscht sie im Bereich der Wirt-Pathogen-Interaktionen und untersucht die Verteidigungsmechanismen des Wirtes sowie die Virulenzmechanismen der Pathogene.

Publikationen
Werbenko E., Gorter D.J.J., Kleimann S., Beckmann D., Waltereit-Kracke V., Reinhardt J., Geers F., Paruzel P., Hansen U., Pap T., ... , Stradal T.E.B., Dankbar B. (2024)
Hem1 is essential for ruffled border formation in osteoclasts and efficient bone resorption
Scientific Reports, 14 (1)

Fey C., Truschel T., Nehlsen K., Damigos S., Horstmann J., Stradal T., May T., ... , Metzger M., Zdzieblo D. (2024)
Enhancing pre-clinical research with simplified intestinal cell line models
J.Tissue Eng., 15

Ravichandran Y., Hänisch J., Murray K., Roca V., Dingli F., Loew D., Sabatet V., Boeda B., ... , Stradal T.E., Etienne-Manneville S. (2024)
The distinct localization of CDC42 isoforms is responsible for their specific functions during migration
J.Cell Biol., 223 (3)

Sum W.C., Ebada S.S., Kirchenwitz M., Wanga L., Decock C., Stradal T.E.B., Matasyoh J.C., Mandi A., ... , Kurtan T., Stadler M. (2023)
Neurite Outgrowth-Inducing Drimane-Type Sesquiterpenoids Isolated from Cultures of the Polypore Abundisporus violaceus MUCL 56355
J.Nat.Prod., 86 (11)

Kirchenwitz M., Halfen J., von Peinen K., Prettin S., Kollasser J., Zur Lage S., Blankenfeldt W., Brakebusch C., Rottner K., ... , Steffen A., Stradal T.E.B. (2023)
RhoB promotes Salmonella survival by regulating autophagy
Eur.J.Cell Biol., 102 (4)

Mitschke N., Chemutai Sum W., Hassan K., Kirchenwitz M., Schrey H., Gerhards L., Kellner H., Stradal T.E.B., ... , Matasyoh J.C., Stadler M. (2023)
Biologically active drimane derivatives isolated from submerged cultures of the wood-inhabiting basidiomycete Dentipellis fragilis
RSC Adv., 13 (37)

Lambert C., Schmidt K., Karger M., Stadler M., Stradal T.E.B., Rottner K. (2023)
Cytochalasans and Their Impact on Actin Filament Remodeling
Biomolecules., 13 (8)

Sum W.C., Ebada S.S., Kirchenwitz M., Kellner H., Ibrahim M.A.A., Stradal T.E.B., ... , Matasyoh J.C., Stadler M. (2023)
Hericioic Acids A-G and Hericiofuranoic Acid; Neurotrophic Agents from Cultures of the European Mushroom Hericium flagellum
J.Agric.Food Chem.

Lambert C., Shao L., Zeng H., Surup F., Saetang P., Aime M.C., Husbands D.R., Rottner K., ... , Stradal T.E.B., Stadler M. (2023)
Cytochalasans produced by Xylaria karyophthora and their biological activities
Mycologia

Stradal T.E.B., Kirchenwitz M., Steffen A. (2023)
Wirkstoffe an der Schnittstelle zwischen Autophagie und Cytoskelettdynamik [/ Active ingredients at the interface between autophagy and cytoskeletal dynamics]
Biospektrum, 29 (2)

Steffen A., Reusch B., Gruteser N., Mainz D., Roncarati R., Baumann A., ... , Stradal T.E.B., Knebel-Mörsdorf D. (2023)
Baculovirus Actin Rearrangement-Inducing Factor 1 Can Remodel the Mammalian Actin Cytoskeleton
Microbiol.Spectr.

Kemkuignou B.M., Lambert C., Schmidt K., Schweizer L., Anoumedem E.G.M., Kouam S.F., Stadler M., ... , Stradal T., Marin-Felix Y. (2023)
Unreported cytochalasins from an acid-mediated transformation of cytochalasin J isolated from Diaporthe cf. ueckeri
Fitoterapia

Hassan K., Matio Kemkuignou B., Kirchenwitz M., Wittstein K., Rascher-Albaghdadi M., Chepkirui C., Matasyoh J.C., Decock C., Köster R.W., ... , Stradal T.E.B., Stadler M. (2022)
Neurotrophic and Immunomodulatory Lanostane Triterpenoids from Wood-Inhabiting Basidiomycota
Int.J.Mol.Sci., 23 (21)

Kirchenwitz M., Stahnke S., Grunau K., Melcher L., Van Ham M., Rottner K., ... , Steffen A., Stradal T.E.B. (2022)
The autophagy inducer SMER28 attenuates microtubule dynamics mediating neuroprotection
Sci.Rep., 12 (1)

Spindler M., Bergmeier W., Stradal T.E.B., Zhang J., Siminovitch K., Nicolai L., ... , Reinhold A., Bender M. (2022)
Novel insights into mouse models of ectopic proplatelet release
Blood Adv.

Pourmoghaddam M.J., Ekiz G., Lambert C., Surup F., Primahana G., Wittstein K., Khodaparast S.A., Voglmayr H., Krisai-Greilhuber I., ... , Stradal T.E.B., Stadler M. (2022)
Studies on the secondary metabolism of Rosellinia and Dematophora strains (Xylariaceae) from Iran
Mycol.Prog., 21 (8)

Kage F., Döring H., Mietkowska M., Schaks M., Grüner F., Stahnke S., Steffen A., Müsken M., ... , Stradal T.E.B., Rottner K. (2022)
Lamellipodia-like actin networks in cells lacking WAVE regulatory complex
J Cell Sci, 135 (15)

Garcia K.Y.M., Quimque M.T.J., Lambert C., Schmidt K., Primahana G., Stradal T.E.B., Ratzenböck A., Dahse H.M., Phukhamsakda C., Stadler M., ... , Surup F., Macabeo A.P.G. (2022)
Antiproliferative and Cytotoxic Cytochalasins from Sparticola triseptata Inhibit Actin Polymerization and Aggregation
J.Fungi.(Basel), 8 (6)

Kirchenwitz M., Stahnke S., Prettin S., Borowiak M., Menke L., Sieben C., Birchmeier C., Rottner K., ... , Stradal T.E.B., Steffen A. (2022)
SMER28 Attenuates PI3K/mTOR Signaling by Direct Inhibition of PI3K p110 Delta
Cells, 11 (10)

Fung T.S., Chakrabarti R., Kollasser J., Rottner K., Stradal T.E.B., ... , Kage F., Higgs H.N. (2022)
Parallel kinase pathways stimulate actin polymerization at depolarized mitochondria
Curr.Biol., 32 (7)

Rottner K., Stradal T.E.B. (2022)
WASP stings into matrix to lead immune cell migration
J.Cell Biol., 221 (2)

Rottner K., Stradal T.E.B., Chen B. (2021)
WAVE regulatory complex
Curr.Biol., 31 (10)

Lambert C., Pourmoghaddam M.J., Cedeno-Sanchez M., Surup F., Khodaparast S.A., Krisai-Greilhuber I., Voglmayr H., ... , Stradal T.E.B., Stadler M. (2021)
Resolution of the Hypoxylon fuscum complex (hypoxylaceae, xylariales) and discovery and biological characterization of two of its prominent secondary metabolites
J.Fungi, 7 (2)

Stahnke S., Döring H., Kusch C., De Gorter D.J.J., Dütting S., Guledani A., Pleines I., Schnoor M., Sixt M., Geffers R., Rohde M., Müsken M., Kage F., Steffen A., Faix J., Nieswandt B., ... , Rottner K., Stradal T.E.B. (2021)
Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion
Curr.Biol., 31 (5 / May)

Dimchev V., Lahmann I., Koestler S.A., Kage F., Dimchev G., Steffen A., Stradal T.E.B., Vauti F., ... , Arnold H.H., Rottner K. (2021)
Induced Arp2/3 Complex Depletion Increases FMNL2/3 Formin Expression and Filopodia Formation
Front.Cell Dev.Biol., 9

Leithner A., Altenburger L.M., Hauschild R., Assen F.P., Rottner K., Stradal T.E.B., Diz-Munoz A., ... , Stein J.V., Sixt M. (2021)
Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse
J.Cell Biol., 220 (4)

Chaoprasid P., Lukat P., Mühlen S., Heidler T., Gazdag E.M., Dong S., Bi W., Rüter C., Kirchenwitz M., Steffen A., Jänsch L., Stradal T.E.B., ... , Dersch P., Blankenfeldt W. (2021)
Crystal structure of bacterial cytotoxic necrotizing factor CNF g
EMBO J, 40 (4)

Felgner S., Preusse M., Beutling U., Stahnke S., Pawar V., Rohde M., Brönstrup M., ... , Stradal T., Häußler S. (2020)
Host-induced spermidine production in motile Pseudomonas aeruginosa triggers phagocytic uptake
Elife., 9 (September)

Wang C., Lambert C., Hauser M., Deuschmann A., Zeilinger C., Rottner K., Stradal T.E.B., Stadler M., ... , Skellam E.J., Cox R.J. (2020)
Diversely Functionalised Cytochalasins through Mutasynthesis and Semi-Synthesis
Chem.Eur.J., 26 (60)

Salzer E., Zoghi S., Kiss M.G., Kage F., Rashkova C., Stahnke S., Haimel M., Platzer R., Caldera M., Ardy R.C., Hoeger B., Block J., Medgyesi D., Sin C., Shahkarami S., Kain R., Ziaee V., Hammerl P., Bock C., Menche J., Dupré L., Huppa J.B., Sixt M., Lomakin A., Rottner K., Binder C.J., Stradal T.E.B., ... , Rezaei N., Boztug K. (2020)
The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity
Sci.Immunol., 5 (49)

Horstmann J.A., Lunelli M., Cazzola H., Heidemann J., Kühne C., Steffen P., Szefs S., Rossi C., Lokareddy R.K., Wang C., Lemaire L., Hughes K.T., Uetrecht C., Schlüter H., Grassl G.A., Stradal T.E.B., Rossez Y., ... , Kolbe M., Erhardt M. (2020)
Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion
Nat.Commun., 11 (1)

Moussa A.Y., Lambert C., Stradal T.E.B., Ashrafi S., Maier W., ... , Stadler M., Helaly S.E. (2020)
New peptaibiotics and a cyclodepsipeptide from ijuhya vitellina: Isolation, identification, cytotoxic and nematicidal activities
Antibiotics, 9 (3)

Dimchev G., Amiri B., Humphries A.C., Schaks M., Dimchev V., Stradal T.E.B., Faix J., Krause M., Way M., ... , Falcke M., Rottner K. (2020)
Lamellipodin tunes cell migration by stabilizing protrusions and promoting adhesion formation
J.Cell Sci., 133 (7)

Kage F., Steffen A., Ellinger A., Ranftler C., Gehre C., Brakebusch C., Pavelka M., ... , Stradal T., Rottner K. (2019)
Author Correction: FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42
Sci Rep., 9 (1)

Schaks M., Döring H., Kage F., Steffen A., Klünemann T., Blankenfeldt W., ... , Stradal T., Rottner K. (2021)
RhoG and Cdc42 can contribute to Rac-dependent lamellipodia formation through WAVE regulatory complex-binding
Small Gtpases., 12 (2)

Bense S., Bruchmann S., Steffen A., Stradal T.E.B., Häußler S., Düvel J. (2019)
Spatiotemporal control of FlgZ activity impacts Pseudomonas aeruginosa flagellar motility
Mol.Microbiol., 111 (6)

Kretz R., Wendt L., Wongkanoun S., Luangsa-ard J.J., Surup F., Helaly S.E., Noumeur S.R., ... , Stadler M., Stradal T.E.B. (2019)
The Effect of Cytochalasans on the Actin Cytoskeleton of Eukaryotic Cells and Preliminary Structure(-)Activity Relationships
Biomolecules., 9 (2)

Franke R., Hinkelmann B., Fetz V., Stradal T., Sasse F., ... , Klawonn F., Brönstrup M. (2019)
xCELLanalyzer: A Framework for the Analysis of Cellular Impedance Measurements for Mode of Action Discovery
SLAS.Discov.

Nauth T., Huschka F., Schweizer M., Bosse J.B., Diepold A., Failla A.V., Steffen A., Stradal T., ... , Wolters M., Aepfelbacher M. (2018)
Visualization of translocons in Yersinia type III protein secretion machines during host cell infection
PLoS.Pathog., 14 (12)

Kluge F., Weissbach J., Weber A., Stradal T., Posern G. (2018)
Regulation of MRTF-A by JMY via a nucleation-independent mechanism
Cell Commun.Signal., 16 (1)

Schaks M., Singh S.P., Kage F., Thomason P., Klünemann T., Steffen A., Blankenfeldt W., Stradal T.E., ... , Insall R.H., Rottner K. (2018)
Distinct Interaction Sites of Rac GTPase with WAVE Regulatory Complex Have Non-redundant Functions in Vivo
Curr.Biol., 28 (11)

Shlomovitz R., Schloen K., Stradal T., Gov N.S. (2013)
Cellular shapes from protrusive and adhesive forces
, 1 (9)

Stradal T.E.B., Schelhaas M. (2018)
Actin dynamics in host-pathogen interaction
FEBS Lett., 592 (22)

Schnoor M., Stradal T.E., Rottner K. (2017)
Cortactin: Cell Functions of A Multifaceted Actin-Binding Protein
Trends Cell Biol., 28 (2)

Böttcher R.T., Veelders M., Rombaut P., Faix J., Theodosiou M., Stradal T.E., Rottner K., Zent R., ... , Herzog F., Fassler R. (2017)
Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading
J.Cell Biol., 216 (11)

Litschko C., Linkner J., Bruhmann S., Stradal T.E.B., Reinl T., Jänsch L., ... , Rottner K., Faix J. (2017)
Differential functions of WAVE regulatory complex subunits in the regulation of actin-driven processes
Eur.J.Cell Biol., 96 (8)

Steffen A., Stradal T.E., Rottner K. (2017)
Signalling Pathways Controlling Cellular Actin Organization
Handb.Exp.Pharmacol., 235

Kage F., Steffen A., Ellinger A., Ranftler C., Gehre C., Brakebusch C., Pavelka M., ... , Stradal T., Rottner K. (2017)
FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42
Sci.Rep., 7 (1)

Stradal T.E.B., Wehland J. (2005)
Actin dynamics and WASP/WAVE proteins
Biospektrum, 11 (3)

Noumeur S.R., Helaly S.E., Jansen R., Gereke M., Stradal T.E., ... , Harzallah D., Stadler M. (2017)
Preussilides A-F, Bicyclic Polyketides from the Endophytic Fungus Preussia similis with Antiproliferative Activity
J.Nat.Prod., 80 (5)

Horstmann J.A., Zschieschang E., Truschel T., de Diego J., Lunelli M., Rohde M., May T., Strowig T., Stradal T., ... , Kolbe M., Erhardt M. (2017)
Flagellin phase-dependent swimming on epithelial cell surfaces contributes to productive Salmonella gut colonization
Cell Microbiol., 19 (8)

Kage F., Winterhoff M., Dimchev V., Mueller J., Thalheim T., Freise A., Bruhmann S., Kollasser J., Block J., Dimchev G., Geyer M., Schnittler H.J., Brakebusch C., Stradal T.E., Carlier M.F., Sixt M., Kas J., ... , Faix J., Rottner K. (2017)
FMNL formins boost lamellipodial force generation
Nat.Commun., 8

Stradal T.E., Costa S.C. (2016)
Type III Secreted Virulence Factors Manipulating Signaling to Actin Dynamics
Curr Top.Microbiol.Immunol. (35)

Leithner A., Eichner A., Muller J., Reversat A., Brown M., Schwarz J., Merrin J., de Gorter D.J., Schur F., Bayerl J., de Vries I, Wieser S., Hauschild R., Lai F.P., Moser M., Kerjaschki D., Rottner K., Small J.V., ... , Stradal T.E., Sixt M. (2016)
Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes
Nat.Cell Biol., 18 (11)

Thiam H.R., Vargas P., Carpi N., Crespo C.L., Raab M., Terriac E., King M.C., Jacobelli J., Alberts A.S., Stradal T., ... , Lennon-Dumenil A.M., Piel M. (2016)
Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments
Nat.Commun., 7

Rottner K., Stradal T.E.B. (2016)
How distinct Arp2/3 complex variants regulate actin filament assembly
Nat.Cell Biol., 18 (1)

Blasche S., Arens S., Ceol A., Siszler G., Schmidt M.A., Hauser R., Schwarz F., Wuchty S., Aloy P., Uetz P., ... , Stradal Theresia E.B., Koegl M. (2014)
The EHEC-host interactome reveals novel targets for the translocated intimin receptor
Scientific Reports, 4

Schluter K., Waschbusch D., Anft M., Hugging D., Kind S., Hanisch J., Lakisic G., Gautreau A., ... , Barnekow A., Stradal Theresia E. (2014)
JMY is involved in anterograde vesicle trafficking from the trans-Golgi network
European Journal of Cell Biology, 93

Steffen A., Ladwein M., Dimchev G.A., Hein A., Schwenkmezger L., Arens S., Ladwein K.I., Holleboom J.M., Schur F., Small J.V., Schwarz J., Gerhard R., Faix J., Stradal Theresia E.B., ... , Brakebusch C., Rottner K. (2013)
Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation
Journal of Cell Science, 126 (20)

Koestler S.A., Steffen A., Nemethova M., Winterhoff M., Luo N., Holleboom J.Margit, Krupp J., Jacob S., Vinzenz M., Schur F., Schluter K., Gunning P.W., Winkler C., Schmeiser C., Faix J., Stradal T.E., ... , Small J.V., Rottner K. (2013)
Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin1
Molecular Biology of the Cell, 24 (18)

Block J., Breitsprecher D., Kuhn S., Winterhoff M., Kage F., Geffers R., Duwe P., Rohn J.L., Baum B., Brakebusch C., Geyer M., Stradal T.E., ... , Faix J., Rottner K. (2012)
FMNL2 Drives Actin-Based Protrusion and Migration Downstream of Cdc42
Current biology, 22 (11)

Hanisch J., Stradal T.E., Rottner K. (2012)
A novel contractility pathway operating in Salmonella invasion
Virulence, 3 (1)

Rottner K., Stradal T.E. (2011)
Actin dynamics and turnover in cell motility
Current Opinion in Cell Biology, 23 (5)

de Groot J.C., Schluter K., Carius Y., Quedenau C., Vingadassalom D., Faix J., Weiss S.M., Reichelt J., Standfuss-Gabisch C., Lesser C.F., Leong J.M., Heinz Dirk W.*, ... , Büssow Konrad*, Stradal Theresia E.* (2011)
Structural Basis for Complex Formation between Human IRSp53 and the Translocated Intimin Receptor Tir of Enterohemorrhagic E. coli
Structure, 19 (9)

Linkner J., Witte G., Stradal Theresia*, Curth U., Faix J. (2011)
High-Resolution X-Ray Structure of the Trimeric Scar/WAVE-Complex Precursor Brk1
PLoS ONE, 6 (6)

Kabaso D., Shlomovitz R., Schloen K., Stradal Theresia*, Gov N.S. (2011)
Theoretical model for cellular shapes driven by protrusive and adhesive forces
PLoS Computational Biology, 7 (5)

Oelkers J.M., Vinzenz M., Nemethova M., Jacob S., Lai F.P., Block J., Szczodrak M., Kerkhoff E., Backert S., Schluter K., Stradal T.E., Small J.V., ... , Koestler S.A., Rottner K. (2011)
Microtubules as platforms for assaying actin polymerization in vivo
PLoS ONE, 6 (5)

Dubielecka P.M., Ladwein K.I., Xiong X., Migeotte I., Chorzalska A., Anderson K.V., Sawicki J.A., Rottner K., ... , Stradal T.E., Kotula L. (2011)
Essential role for Abi1 in embryonic survival and WAVE2 complex integrity
Proceedings of the National Academy of Sciences USA, 108 (17)

Hänisch J., Kolm R., Wozniczka M., Bumann D., Rottner K., Stradal T.E. (2011)
Activation of a RhoA/Myosin II-Dependent but Arp2/3 Complex-Independent Pathway Facilitates Salmonella Invasion
Cell Host and Microbe, 9 (4)

Breitsprecher D., Kiesewetter A.K., Linkner J., Vinzenz M., Stradal Theresia E.*, Small J.V., Curth U., ... , Dickinson R.B., Faix J. (2011)
Molecular mechanism of Ena/VASP-mediated actin-filament elongation
Embo Journal, 30 (3)

Stradal Theresia B.*, Backert S. (2010)
Host-pathogen interaction: How EHEC influence the actin cytoskeleton of the host cell [Wirt-Pathogen-Interaktion wie EHEC das Aktinzytoskelett der Wirtszelle beeinflussen]
Biospektrum, 16 (6)

Horn J., Wang X., Reichardt P., Stradal Theresia E.*, Warnecke N., Simeoni L., Gunzer Matthias*, Yablonski D., ... , Schraven B., Kliche S. (2009)
Src homology 2-domain containing leukocyte-specific phosphoprotein of 76 kDa is mandatory for TCR-mediated inside-out signaling, but dispensable for CXCR4-mediated LFA-1 activation, adhesion, and migration of T cells
Journal of Immunology, 183 (9)

Tahirovic S., Hellal F., Neukirchen D., Hindges R., Garvalov B.K., Flynn K.C., Stradal Theresia E.*, Chrostek-Grashoff A., ... , Brakebusch C., Bradke F. (2010)
Rac1 regulates neuronal polarization through the WAVE complex
Journal of Neuroscience, 30 (20)

Klink B.U., Barden S., Heidler T.V., Borchers C., Ladwein M., Stradal T.B., ... , Rottner K., Heinz D.W. (2010)
Structure of Shigella IpgB2 in complex with human RhoA: implications for the mechanism of bacterial guanine nucleotide exchange factor mimicry
Journal of Biological Chemistry, 285 (22)

Hänisch J., Ehinger J., Ladwein M., Rohde M., Derivery E., Bosse T., Steffen A., Bumann D., Misselwitz B., Hardt W.D., Gautreau A., ... , Stradal T.E., Rottner K. (2010)
Molecular dissection of Salmonella-induced membrane ruffling versus invasion
Cellular Microbiology, 12 (1)

Rottner K., Stradal Theresia E.* (2009)
Poxviruses taking a ride on actin: new users of known hardware
Cell Host and Microbe, 6 (6)

Giuliani C., Troglio F., Bai Z., Patel F.B., Zucconi A., Malabarba M.G., Disanza A., Stradal Theresia B.*, Cassata G., Confalonieri S., Hardin J.D., Soto M.C., ... , Grant B.D., Scita G. (2009)
Requirements for F-BAR proteins TOCA-1 and TOCA-2 in actin dynamics and membrane trafficking during Caenorhabditis elegans oocyte growth and embryonic epidermal morphogenesis
PLoS Genetics, 5 (10)

Lai F.P., Szczodrak M., Oelkers J.M., Ladwein M., Acconcia F., Benesch S., Auinger S., Faix J., Small J.V., Polo S., ... , Stradal T.E., Rottner K. (2009)
Cortactin Promotes Migration and PDGF-induced Actin Reorganization by Signaling to Rho-GTPases
Molecular Biology of the Cell, 20 (14)

Stradal Theresia E.* (2008)
The regulation of cellular protrusions
Zellbiologie Aktuell, 34

Faix J., Breitsprecher D., Stradal T.E.B., Rottner K. (2009)
Filopodia: Complex models for simple rods
The International Journal of Biochemistry and Cell Biology, 41 (8-9)

Weiss S.M., Ladwein M., Schmidt D., Ehinger J., Lommel S., Städing K., Beutling U., Disanza A., Frank R., Jänsch L., Scita G., Gunzer F., ... , Rottner K., Stradal T.E. (2009)
IRSp53 links the enterohemorrhagic E. coli effectors Tir and EspFU for actin pedestal formation
Cell Host and Microbe, 5 (3)

Block J., Stradal T.E.B., Hanisch J., Geffers R., Kostler S.A., Urban E., Small J.V., ... , Rottner K., Faix J. (2008)
Filopodia formation induced by active mDia2/Drf3
Journal of Microscopy, 231 (3)

Beutling U., Stading K., Stradal Theresia E.B.*, Frank Ronald* (2008)
Large-scale analysis of protein-protein interactions using cellulose-bound peptide arrays
Advances in Biochemical Engineering/Biotechnology, 110

Derivery E., Fink J., Martin D., Houdusse A., Piel M., Stradal Theresia E.B.*, ... , Louvard D., Gautreau A. (2008)
Free Brick1 is a trimeric precursor in the assembly of a functional wave complex
PLoS ONE, 3 (6)

Lai F.P.L., Szczodrak M., Block J., Faix J., Breitsprecher D., Mannherz H.G., Stradal Theresia E.B.*, Dunn G.A., ... , Small J.V., Rottner C. (2008)
Arp2/3 complex interactions and actin network turnover in lamellipodia
The EMBO Journal, 27 (7)

Bosse T., Ehinger J., Czuchra A., Benesch S., Steffen A., Wu X., Schloen K., Niemann H.H., Scita G., Stradal T.E.B., ... , Brakebusch C., Rottner K. (2007)
Cdc42 and phosphoinositide 3-kinase drive Rac-mediated actin polymerization downstream of c-Met in distinct and common pathways
Molecular and Cellular Biology, 27 (19)

Ménasché G., Kliche S., Chen E.J., Stradal Theresia E.B.*, Schraven B., Koretzky G. (2007)
RIAM links the ADAP/SKAP-55 signaling module to Rap1 facilitating TCR-mediated integrin activation
Molecular and Cellular Biology, 27

Chmielowiec J., Borowiak M., Morkel M., Stradal Theresia E.B.*, Munz B., Werner S., Wehland Jürgen*, ... , Birchmeier Carmen, Birchmeier Walter (2007)
c-Met is essential for wound healing in the skin
Journal of Cell Biology, 177 (1)

Stradal Theresia E.B.*, Pusch R., Kliche S. (2006)
Molecular regulation of cytoskeletal rearrangements during T cell signalling

Disanza A., Mantoani S., Hertzog M., Gerboth S., Frittoli E., Steffen A., Berhoerster K., Kreienkamp H.J., Milanesi F., Di Fiore P.P., Ciliberto A., ... , Stradal Theresia E.B.*, Scita G. (2006)
Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complex
Nature Cell Biology, 8 (12)

Rottner K., Kaverina I.N., Stradal Theresia E.B.* (2006)
Cytoskeleton proteins
, 3rd

Frese S., Schubert Wolf-Dieter*, Findeis A.C., Marquardt T., Roske Y.S., ... , Stradal Theresia E.B.*, Heinz Dirk W.* (2006)
Phosphotyrosine binding specificities of Nck1 and Nck2
Journal of Biological Chemistry, 281

Steffen A., Faix J., Resch G.P., Linkner J., Wehland J., Small J.V., ... , Rottner K., Stradal T.E.B. (2006)
Filopodia formation in the absence of functional WAVE- and Arp2/3-complex
Molecular Biology of the Cell, 17

Schirenbeck A., Arasada R., Bretschneider T., Stradal Theresia E.B.*, Schleicher M., Faix J. (2006)
The bunding activity of vasodilator-stimulated phosphoprotein is required for filopodium formation
Proceedings of the National Academy of Sciences of the United States of America, 103

Stradal T.E.B., Scita G. (2006)
Protein complexes regulating cellular actin assembly
Current Opinion in Cell Biology, 8

Stradal T.E.B., Wehland J. (2005)
Aktindynamik und WASP/WAVE-Proteine/Actin dynamics and WASP/WAVE proteins
Biospektrum, 11

Innocenti M., Gerboth S., Rottner K., Lai Frank P.L., Hertzog M., Stradal T.E.B., Frittoli E., Didry D., Polo S., Disanza A., Benesch S., Di Fiore P.P., ... , Carlier M.-F., Scita G. (2005)
Abi1regulates the activity of N-WASP and WAVE in distinct actin-based processes
Nature Cell Biology, 7 (10)

Benesch S., Polo S., Lai F.P.L., Anderson K.I., Stradal T.E.B., ... , Wehland J., Rottner K. (2005)
N-WASP deficiency impairs EGF internalization and actin assembly at clathrin coated pits
Journal of Cell Science, 118

Rottner K., Stradal T.E.B., Wehland J. (2005)
Bacteria - host cell interactions at the plasma membrane: stories on actin cytoskeleton subversion
Developmental Cell, 9

Chandrasekar I., Stradal T.E.B., Holt M.R., Entschladen F., Jockusch B.M., Ziegler W.H. (2005)
Vinculin acts as a sensor in lipid regulation of adhesion-site turnover
Journal of Cell Science, 118

Dubois T., Paleotti O., Mironov A.A., Fraisier V., Stradal T.E.B., De Matteis M.A., ... , Franco M., Chavrier P. (2005)
Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics
Nature Cell Biology, 7 (4)

Jenzora A., Behrendt B., Small J.V., Wehland J., Stradal T.E.B. (2005)
PREL1 links Ras signalling to actin remodeling via Ena/VASP proteins
Febs Letters, 579

Stradal T.E.B., Lommel S., Wehland J., Rottner K. (2005)
Host-pathogen interactions and cell motility: learning from bacteria
(12)

Disanza A., Carlier M.F., Stradal T.E.B., Didry D., Frittoli E., Confalonieri S., Croce A., Wehland J., ... , DiFiore P.P., Scita G. (2004)
Eps8 controls actin-based motility by capping the barbed ends of actin filaments
Nature Cell Biology, 6

Rottner K., Lommel S., Wehland J., Stradal T.E.B. (2004)
Pathogen-induced actin filament rearrangement in infectious diseases
Journal of Pathology, 204

Pacholsky D., Himmel M., Löw T., Stradal T.E.B., Rottner K., ... , Fürst D.O., Van der Ven P.F. (2004)
Xin repeats define a novel actin binding motif
Journal of Cell Science, 117

Stradal T.E.B., Rottner K., Disanza A., Confalonieri S., Innocenti M., Scita G. (2004)
Regulation of actin dynamics by WASF and WAVE family proteins
Trends in Cell Biology, 14

Innocenti M., Zucconi A., Disanza A., Frittoli E., Areces L., Steffen A., Stradal T.E.B., Di Fiore P.P., ... , Carlier M.F., Scita G. (2004)
Abi1 is essential for the formation and activation of a WAVE2 signaling complex mediating Rac-dependent actin remodeling
Nature Cell Biology, 6

Steffen A., Rottner K., Ehinger J., Innocenti M., Scita G., ... , Wehland J., Stradal T.E.B. (2004)
Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation
Embo Journal, 23 (4)

Stradal T.B., Sechi A.S., Wehland J., Rottner K. (2003)
The cytoskeleton

Kaverina I., Stradal T.E.B., Gimona M. (2003)
Prodosome formation in cultured A7r5 vascular smooth muscle cells requires Arp2/3-dependent de-novo actin polymerization at discrete microdomains
Journal of Cell Science, 116

Small J.V., Stradal T., Vignal E., Rottner K. (2002)
The lamellipodium: Where motility begins.
Trends in Cell Biology, 12

Benesch S., Lommel S., Steffen A., Stradal T.E., Scaplehorn N., Way M., ... , Wehland J., Rottner K. (2002)
Phosphatidylinositol 4,5-Biphosphate (PIP2)-induced Vesicle Movement Depends on N-WASP and Involves Nck, WIP, and Grb2*210
Journal of Biological Chemistry, 277 (40)

Stradal T.B., Courtney K., Rottner K., Hahne P., Small J.V., Pendergast A.M. (2001)
The Abl-interactor (Abi) proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia.
Current biology, 11

Stradal T.B., Troxler H., Heizmann C.W., Gimona M. (2000)
Mapping the zinc ligands of S100A2 by site-directed mutagenesis
Journal of Biological Chemistry, 275