Publication database of the HZI

Perspicace,E., Giorgio,A., Carotti,A., Marchais-Oberwinkler,S., Hartmann,Rolf W. (2013)

Novel N-methylsulfonamide and retro-N-methylsulfonamide derivatives as 17b[beta]-hydroxysteroid dehydrogenase type 2 (17b[beta]-HSD2) inhibitors with good ADME-related physicochemical parameters

European Journal of Medicinal Chemistry 69

DOI: 10.1016/j.ejmech.2013.08.026 PubMed

Lu,C., Maurer,C.K., Kirsch,B., Steinbach,A., Hartmann,Rolf W. (2014)

Overcoming unexpected functional inversion of PqsR antagonist in Pseudomonas aeruginosa led to the first in vivo potent anti-virulence agent targeting pqs quorum sensing

Angewandte Chemie 53 (4)

DOI: 10.1002/anie.201307547 HZI-Repositorium PubMed

Hinsberger,S., Husecken,K., Groh,M., Negri,M., Haupenthal,J., Hartmann,Rolf W. (2013)

Discovery of Novel Bacterial RNA Polymerase Inhibitors: Pharmacophore-Based Virtual Screening and Hit Optimization

Journal of Medicinal Chemistry 56

Grombein,C.M., Hu,Q., Heim,R., Huch,V., Hartmann,Rolf W. (2013)

Unexpected results of a S N,Ar

Tetrahedron Letters 54

DOI: 10.1016/j.tetlet.2013.09.111 HZI-Repositorium PubMed

Gobbi,S., Hu,Q., Negri,M., Zimmer,C., Belluti,F., Rampa,A., ... , Hartmann,Rolf W., Bisi,A. (2013)

Modulation of cytochromes P450 with xanthone-based molecules: from aromatase to aldosterone synthase and steroid 11beta-hydroxylase inhibition

Journal of Medicinal Chemistry 56 (4)

DOI: 10.1021/jm301844q

Elgaher,W.A.M., Fruth,M., Groh,M., Hartmann,Rolf W. (2013)

Expanding the scaffold for bacterial RNA polymerase inhibitors: Design, synthesis and structure activity relationships of ureido-heterocyclic-carboxylic acids

RSC Advances

DOI: 10.1039/C3RA45820B HZI-Repositorium PubMed

Nermin,S.A., Ali,A.H., El-Nashar,S.M., Gary,B.D., Fajardo,A.M., Tinsley,H.N., Piazza,G.A., ... , Negri,M., Abadi,A.H. (2012)

Exploring the PDE5 H-pocket by ensemble docking and structure-based design and synthesis of novel b[beta]-carboline derivatives

European Journal of Medicinal Chemistry 57

DOI: 10.1016/j.ejmech.2012.09.029 HZI-Repositorium PubMed

Haidar,S., Boettcher,S., Al Maridini,M.A., Hartmann,Rolf W. (2012)

Purity of five generic bulk motelukast sodium using liquid chromatography/mass spectrometry

International Journal of Pharmacy and Pharmaceutical 4

Sahner,J.Henning, Brengel,Christian, Storz,Michael P., Groh,Matthias, Plaza,Alberto, ... , Müller,Rolf, Hartmann,Rolf W. (2013)

Combining in Silico and Biophysical Methods for the Development of Pseudomonas aeruginosa Quorum Sensing Inhibitors: An Alternative Approach for Structure-Based Drug Design

Journal of Medicinal Chemistry 56

Buschart,A., Gremmer,K., El-Mowafy,M., van den Heuvel,Joop, Müller,Peter P., Bilitewski,Ursula (2012)

A novel functional assay for fungal histidine kinases group III reveals the role of HAMP domains for fungicide sensitivity

Journal of Biotechnology 157 (1)

Publication Database