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 A view inside a laboratory; two hands wearing blue gloves working with a pipette
News
Bacteria have spent decades evolving resistance to virtually every antibiotic we have thrown at them. To stay ahead, new drugs must hit targets that existing antibiotics have never touched. A research team at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) has now developed a series of synthetic drug candidates that do exactly that: By blocking an essential molecular supply system, these molecules cut off the bacteria's essential vitamins supply and starve them to death. The team published its findings in two studies back to back in the Journal of Medicinal Chemistry.
21.07.2026
Macrophages under an electron microscope
News
Macrophages are considered the “scavenger cells” of the immune system, but some pathogens exploit these very cells as hiding places. Researchers from the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and Philipps-Universität Marburg have now discovered a mechanism that helps immune cells to balance their response to infection: a long non-coding ribonucleic acid called SAILR, which acts as an apoptosis regulator. The findings were published recently in the journal PNAS.
20.07.2026
Portrait
News
Prof. Hortense Slevogt, research group leader at the Helmholtz Centre for Infection Research (HZI) and lead senior physician at Hannover Medical School (MHH), has been appointed to the Commission on Anti-Infectives, Resistance and Therapy (ART) at the Robert Koch Institute (RKI). The ART Commission is an independent expert panel at the RKI that develops recommendations on the rational use of anti-infectives based on current scientific evidence. Its goal is to ensure the effective use of anti-infectives while limiting the emergence and spread of resistant pathogens.
15.07.2026
Photo of Leonard Knegendorf at an office workstation
News
Premature babies in the intensive care unit are particularly at risk of becoming infected with potentially pathogenic bacteria. A team of doctors in Hanover has now investigated which external factors play a role in this. They concluded that climatic conditions have an influence. The study was led and designed by Dr Leonard Knegendorf, a clinician-scientist at TWINCORE, the Centre for Experimental and Clinical Infection Research. The findings were published in the scientific journal "Antimicrobial Resistance & Infection Control". TWINCORE is a joint institution of the Helmholtz Centre for Infection Research (HZI) and Hannover Medical School (MHH).
13.07.2026
Collage of portraits of Alexander Titz and Christian Sieben
News
New broad-spectrum antiviral agents are considered an important contribution to pandemic preparedness. A project led by Alexander Titz, Professor of Organic and Pharmaceutical Chemistry at Saarland University (UdS), and Prof. Christian Sieben, research group leader at the Helmholtz Centre for Infection Research (HZI), aims to develop such active compounds to fill a gap in pandemic prevention. To achieve this, the two researchers intend to block a step that occurs at the very beginning of viral infection: the binding of viruses to sugar molecules on the cell surface. The Volkswagen Foundation is now funding the development of such inhibitors with almost one million euros.
06.07.2026
Collage of Portraits of Mark Brönstrup and Henning Jacobsen
News
The Falling Walls Foundation has nominated two projects from the Helmholtz Centre for Infection Research (HZI) for the “Science Breakthrough of the Year 2026.” The award recognizes groundbreaking scientific advances that break down walls in science and have a global impact. The PROTON team led by Prof. Mark Brönstrup was nominated for the development of a novel antibiotic technology against the pathogen Staphylococcus aureus. In addition, the ENDURIVAC team, represented by Dr. Henning Jacobsen, was recognized for the development of a vaccine platform that induces long-term immunity against respiratory pathogens.
03.07.2026

HZI in the media

... ist Leiterin der Abteilung Epidemiologie am Helmholtz-Zentrum für Infektionsforschung (HZI) und Mitglied der Ständigen Impfkommission ...

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Focus Online

von Mikroorganismen und Zellkulturen und des Helmholtz-Zentrums für Infektionsforschung zwei bislang unbekannte Naturstoffe entdeckt. Die

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Bionity.COM

Researchers at the Helmholtz Centre for Infection Research (HZI) and its Saarland University partner site, the Helmholtz Institute for

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Scienmag Science Magazine

experimental and modeling study led by scientists at the Helmholtz Centre for Infection Research in Braunschweig. The researchers found that

26.10.2026
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Bioengineer.org

... am Helmholtz Zentrum für Infektionsforschung (HZI) und dessen Saarbrücker Standort, dem Helmholtz-Institut für Pharmazeutische ...

26.10.2026
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Verband Deutscher Biologen e.V.

Dr. Milan Gerovac, Nachwuchsgruppenleiter am Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig, erhält den begehrten ...

24.10.2026
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Homburg

heads the Research Group “Molecular Cell Biology” at the Helmholtz Center for Infection Research (HZI), has shed new light on the central

23.10.2026
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Health Medicine Network

... “

 

Das Helmholtz-Zentrum für Infektionsforschung: Wissenschaftler:innen am Helmholtz-Zentrum für Infektionsforschung (HZI) untersuchen ...

22.10.2026
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DeutschesGesundheitsPortal

... Lange, Leiterin der Abteilung Epidemiologie am Helmholtz-Zentrum für Infektionsforschung in Braunschweig und Mitglied der Ständigen ...

22.10.2026
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DIE WELT

... befallen. Am HZI in Braunschweig wird daran geforscht.

 

Am Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig ...

22.10.2026
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NDR Norddeutscher Rundfunk

are extremely complex.

 

Researchers at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) have now shown that artificial

21.10.2026
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Phys.org

Würzburg (JMU) und dem Helmholtz-Institut für RNA-basierte Infektionsforschung (HIRI), einem Standort des HZI in ...

20.10.2026
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Regional Heute

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