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Electron micrograph of coccal bacteria growing in chains

News

Influenza viruses can trigger epigenetic changes in the alveolar epithelium, the cell layer that lines the alveoli, permanent changes in gene activity without changing the DNA itself. These changes have a lasting effect on subsequent immune responses and result in the body no longer being able to react appropriately to the bacterial pathogens in the event of a subsequent infection with pneumococci. A research team at the Helmholtz Centre for Infection Research (HZI) and the University Hospital Magdeburg (UMMD) has published new findings on the long-term consequences of an influenza A infection in a mouse model in the journal Cell Communication and Signaling.

04.07.2025

HZI Campus

Preparing for historical specimen sampling

Story

From 4 to 6 June 2025, the Department “Pathogen Evolution” led by Prof. Dr. Sébastien Calvignac-Spencer at the Helmholtz Institute for One Health (HIOH) conducted a combined retreat and sampling mission at the Institute of Pathology of the University of Veterinary Medicine Vienna — a key collaboration partner for accessing and studying historical pathological specimens in veterinary medicine. HIOH is a site of the Helmholtz Centre for Infection Research (HZI). The visit focused on collecting around 60 historical tissue samples for molecular genetic analyses related to animal disease research, while also offering time for internal discussions on lab optimization, project development, and team building.

03.07.2025

HIOH

News

If an intestinal inhabitant such as the bacterium Escherichia coli (E. coli) becomes resistant to many antibiotics, it can cause serious health problems if it enters the bloodstream. How can such potentially dangerous multi-resistant bacteria be effectively removed from the gut? Researchers from the Helmholtz Centre for Infection Research (HZI), in collaboration with researchers from Hannover Medical School (MHH), explored this question in their latest study.

03.07.2025

HZI Campus

Pseudocolored cells of Pseudomonas aeruginosa

News

An international research team led by the Helmholtz Centre for Infection Research (HZI) has discovered a new strategy used by the human pathogen Pseudomonas aeruginosa to adapt to its host. In the journal Proceedings of the National Academy of Sciences (PNAS), the researchers demonstrate that epigenetic processes can lead to the emergence of distinct sub-populations within genetically identical bacterial populations. This heterogeneity may be a key for bacteria to establish successful infections.

02.07.2025

HZI Campus

TWINCORE

BRICS

News

Habitat loss, climate change, and globalization create new transmission routes for pathogens. Therefore, the One Health approach considers humans, animals and nature together. Prof. Fabian Leendertz is founding director of the Helmholtz Institute for One Health (HIOH) in Greifswald, which links health research, ecology, and prevention to better prepare for future pandemics. In this episode of the HZI podcast “InFact”, Leendertz explains how zoonoses, or diseases that jump from animals to humans, develop, and why protecting the environment is central to this process.

02.07.2025

HIOH

News

A research project at the Helmholtz Institute for One Health (HIOH), a site of the Helmholtz Centre for Infection Research (HZI), has been awarded the Undine Award 2025 in the “Habitat” category. The prize was presented in Stuttgart. In the award-winning project, a research team led by Prof. Katharina Schaufler is investigating antimicrobial resistance (AMR) in the surface water of the Greifswald Bodden. Targeted science communication is also an important part of the project in order to raise public awareness of the issue. Schaufler heads the department “Epidemiology and Ecology of Antimicrobial Resistance” at the HIOH and receives prize money of 20,000 euros and an image film with the Undine Award.

19.06.2025

HIOH

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HZI in the media

Hochschule Hannover, die Universitätsmedizin Göttingen, das Helmholtz-Zentrum für Infektionsforschung in Braunschweig sowie die KI-

07.11.2025

Heise online

... , Leiter der Forschungsgruppe Mikrobielle Wirkstoffe am Helmholtz-Zentrum für Infektionsforschung, zu bedenken. Das erste ...

07.11.2025

Leipziger Volkszeitung (LVZ)

Quelle: Pressemitteilung

HZI-Helmholtz Zentrum für Infektionsforschung ...

04.11.2025

LaborPraxis

Forschende des Helmholtz-Zentrums für Infektionsforschung und der Universität Würzburg entwickeln derzeit einen Kaugummi, der Grippeviren

04.11.2025

Arbeitsmedizin-Sozialmedizin-Umweltmedizin

... Vakzinologie und angewandte Mikrobiologie am Helmholtz-Zentrum für Infektionsforschung. Die M2-Membranproteinhemmer verhindern ...

02.11.2025

Augsburger Allgemeine

... etwas dran ist“, erklärt Biologe Marc Stadler vom Helmholtz-Zentrum für Infektionsforschung gegenüber der Barmer-Krankenkasse. „Es ...

30.10.2025

bild der wissenschaft

could be reintroduced at any time. Epidemiologists at the Helmholtz Center for Infection Research (HZI) have now shown that many people do

23.10.2025

MSN.com

... eingeschleppt werden könnte. Epidemiolog:innen des Helmholtz-Zentrums für Infektionsforschung (HZI) haben nun gezeigt, dass ...

23.10.2025

innovations report

this development, a research team at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), in collaboration with the Swiss

22.10.2025

Phys.org

Malaria-Medikamentes ermöglichen könnte. Das HIPS ist ein Standort des Helmholtz-Zentrums für Infektionsforschung in Zusammenarbeit mit ...

22.10.2025

Verband Deutscher Biologen e.V.

(Bild: DOI: 10.1021/jacs.5c08354 / Hips / CC BY 4.0) Wissenschaftler am Hips entwickelten eine Plattform zur Produktion von Furanoliden, die effektiv gegen Bakterien und Krebszellen wirken können und vielversprechende Wirkstoffe darstellen.

21.10.2025

PROCESS

at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), in partnership with the Helmholtz Centre for Infection Research (HZI

20.10.2025

Bioengineer.org

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