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HZI Podcast InFact
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Bacteriophages are viruses that specifically attack bacteria but are harmless to humans. They attach themselves to bacteria, inject their genetic material, and reprogram the cells so that they only produce phage genetic material – until they eventually burst and release new phages. In theory, phages are a promising alternative to antibiotics, but in practice, major challenges must be overcome. In this episode of the HZI podcast “InFact”, Jun. Prof. Jens Hör, head of the junior research group “Molecular Principles of RNA Phages” at the Helmholtz Institute for RNA-based Infection Research (HIRI), talks about his research on this fascinating tool in the fight against resistant germs.
04.09.2025
Illustration Scientist and DNA strand
News
The Helmholtz Centre for Infection Research (HZI) in Braunschweig succeeded with three project proposals in the zukunft.niedersachsen funding program of the Lower Saxony Ministry of Science and Culture (MWK) and the Volkswagen Foundation. In the “MacroAB-Delivery” project, a research team coordinated by Prof. Dagmar Wirth from the HZI aims to advance a new method for the local treatment of implant-associated infections. The “MoreHealth” project, coordinated at Hannover Medical School (MHH) with the participation of Prof. Jochen Hühn (HZI), is establishing an infrastructure with comprehensive health data that can be analyzed for various diseases with a focus on individual risk and severity. Prof. Alice McHardy and her team at the HZI are involved in the INDIVO research network, which is coordinated at the MHH and seeks new methods for more accurate diagnosis and targeted treatment of bacterial infections in liver cirrhosis patients. Five joint projects to expand personalized medicine are being funded as part of zukunft.niedersachsen with a total budget of nine million euros.
01.09.2025
DNA strand and virus cells
News
Why do people infected with the human immunodeficiency virus (HIV) often suffer from cardiovascular, liver, and other comorbidities? Researchers at the Centre for Individualised Infection Medicine (CiiM) investigated this question as part of the 2000HIV study, a multi-omics cohort coordinated by several research centers in the Netherlands. They identified various molecules and mechanisms that could be linked to the development of these comorbidities. The scientists are making the extensive results of their study freely available. They hope that they will be used for new research approaches and lead to a better understanding of the underlying causes and to helpful therapies. The researchers have now published their study results in the journal Nature Medicine. The CiiM is a joint institution of the Helmholtz Centre for Infection Research (HZI) and Hannover Medical School (MHH).
21.08.2025
Portrait of Michael Manns
News
The former President of Hannover Medical School (MHH) and Clinical Director of the Helmholtz Centre for Infection Research (HZI), Prof. Michael P. Manns, passed away on 15 August 2025. Manns succumbed to a tumor disease at the age of 73. As a renowned gastroenterologist, he belonged to the worldwide scientific elite, was one of the most cited scientists, and enriched both the German and international research landscape as an excellent communicator. Until the very end, Manns was still actively involved in research at the MHH and promoted the scientific organization of the Centre for Individualised Infection Medicine (CiiM), a joint institution of the HZI and the MHH, which he co-founded. Manns also supported another joint center of the HZI and MHH, the TWINCORE, with his extensive expertise.
18.08.2025
Electron micrograph of Klebsiella oxytoca
News
A balanced gut microbiome not only contributes to digestion, but is also an important protective factor against infections. Researchers at the Helmholtz Centre for Infection Research (HZI) led by Prof. Till Strowig, scientist in the German Center for Infection Research (DZIF), want to harness the power of the microbiome to prevent serious infections. They have discovered that bacteria of the species Klebsiella oxytoca can displace pathogenic bacteria from the gut and want to develop a living biotherapeutic based on this finding. The DZIF is now providing 2.2 million euros in funding for product development until the first tests on humans.
07.08.2025
World map
News
Since the start of the SARS-CoV-2 pandemic, several variants of the virus have developed into Variants of Concern (VOCs), as classified by the World Health Organization (WHO). VOCs are virus variants that are predicted or known to cause large waves of infections due to their altered phenotypic characteristics and with risk of altering disease severity, reducing vaccine effectiveness or otherwise leading to increased burden of health care systems. Researchers at the Helmholtz Centre for Infection Research (HZI) and the German Center for Infection Research (DZIF) have developed an analysis method to detect VOC early in their development. The study was published in the journal Nature Communications.
22.07.2025

HZI in the media

new antiviral medicines, says virologist Christian Sieben of the Helmholtz Centre for Infection Research in Germany.

 

Earlier in 2025, for

10.11.2025
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The Press

Hochschule Hannover, die Universitätsmedizin Göttingen, das Helmholtz-Zentrum für Infektionsforschung in Braunschweig sowie die KI-

07.11.2025
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Heise online

... , Leiter der Forschungsgruppe Mikrobielle Wirkstoffe am Helmholtz-Zentrum für Infektionsforschung, zu bedenken. Das erste ...

07.11.2025
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Leipziger Volkszeitung (LVZ)

Quelle: Pressemitteilung

 

HZI-Helmholtz Zentrum für Infektionsforschung ...

04.11.2025
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LaborPraxis

Forschende des Helmholtz-Zentrums für Infektionsforschung und der Universität Würzburg entwickeln derzeit einen Kaugummi, der Grippeviren

04.11.2025
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Arbeitsmedizin-Sozialmedizin-Umweltmedizin

... Vakzinologie und angewandte Mikrobiologie am Helmholtz-Zentrum für Infektionsforschung. Die M2-Membranproteinhemmer verhindern ...

02.11.2025
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Augsburger Allgemeine

... etwas dran ist“, erklärt Biologe Marc Stadler vom Helmholtz-Zentrum für Infektionsforschung gegenüber der Barmer-Krankenkasse. „Es ...

30.10.2025
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bild der wissenschaft

could be reintroduced at any time. Epidemiologists at the Helmholtz Center for Infection Research (HZI) have now shown that many people do

23.10.2025
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MSN.com

... eingeschleppt werden könnte. Epidemiolog:innen des Helmholtz-Zentrums für Infektionsforschung (HZI) haben nun gezeigt, dass ...

23.10.2025
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innovations report

this development, a research team at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), in collaboration with the Swiss

22.10.2025
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Phys.org

Malaria-Medikamentes ermöglichen könnte. Das HIPS ist ein Standort des Helmholtz-Zentrums für Infektionsforschung in Zusammenarbeit mit ...

22.10.2025
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Verband Deutscher Biologen e.V.

(Bild: DOI: 10.1021/jacs.5c08354 / Hips / CC BY 4.0) Wissenschaftler am Hips entwickelten eine Plattform zur Produktion von Furanoliden, die effektiv gegen Bakterien und Krebszellen wirken können und vielversprechende Wirkstoffe darstellen.

21.10.2025
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PROCESS

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