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Scientists at the Helmholtz Centre for Infection Research (HZI) rely on working with laboratory animals to research infectious diseases in more detail and to understand the complex interactions between pathogens and their hosts. To this end, the HZI operates a central animal facility for breeding and keeping mice and hamsters.

24.04.2024

HZI Campus

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Fabian Leendertz, Director of the Helmholtz Institute for One Health (HIOH) in Greifswald, and his team have been working for more than a decade in the south of the Central African Republic, in the Dzanga Sangha Conservation Areas. As part of a close collaboration with the WWF of the Central African Republic, the HIOH supports the monitoring of the health status of wildlife in these protected areas, with a focus on lowland gorillas. Over the years, activities have been expanded to better characterize the interface between humans, animals and the environment in this extraordinary ecosystem.

11.04.2024

HIOH

HZI Campus

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Vaccinations do not always live up to what we would want them to do – so far, anyway. But they are still invaluable for our health and life in our communities.

12.12.2023

HZI Campus

Symbol image; hand turns an equal and an unequal sign between the symbols for male and female gender

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Men are more susceptible to a number of chronic infections, while women, in turn, are more likely to overreact to infections. The underlying reason and why it needs to be taken into account more in clinical practice in the future. Am I more likely to have a mild case of pneumonia or is it more likely to be life-threatening? What is my risk of side effects from COVID-19 vaccination? Do I belong to a group of people who are more likely to contract chronic viral hepatitis than others? The answers to these questions vary – depending on your sex and gender. Hospitalised for pneumonia, males are twice as likely as females to need to be transferred to intensive care (Source). Females, in turn, are more than twice as likely as males to suffer side effects from the COVID-19 vaccine. And chronic hepatitis B is more common among males than among females.

08.12.2023

CiiM

HZI Campus

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On the World Day for Laboratory Animals April 24, 2023, special attention is paid to the use of animals for research and development of products for humans. In drug research, among other areas, extensive animal testing is a firmly prescribed part of the approval process for new drugs. However, a reduction in the number of laboratory animals is increasingly in sight due to new approaches. At the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), a site of the Helmholtz Centre for Infection Research (HZI) in collaboration with Saarland University, researchers are successfully developing alternative models and have already received awards for their work.

24.04.2023

HIPS

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In their search for new substances that are effective against infectious diseases, researchers at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) are extracting natural substances from soil bacteria. They are getting help from the public in the course of a citizen science project, which this year recruited citizen scientists from all over Germany on board the exhibition ship “MS Wissenschaft”.

06.10.2022

HIPS

HZI in the media

Credit: Nucleic Acids Research (2024). DOI: 10.1093/nar/gkae281

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The half-life of RNA in Salmonella is three times shorter than expected. Credit: Manfred Rohde, HZI/Manfred Rohde

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