Blood vessel organoid
Scientists at the Helmholtz Centre for Infection Research (HZI) rely on working with laboratory animals to research infectious diseases in more detail and to understand the complex interactions between pathogens and their hosts. To this end, the HZI operates a central animal facility for breeding and keeping mice and hamsters.
Fabian Leendertz, Director of the Helmholtz Institute for One Health (HIOH) in Greifswald, and his team have been working for more than a decade in the south of the Central African Republic, in the Dzanga Sangha Conservation Areas. As part of a close collaboration with the WWF of the Central African Republic, the HIOH supports the monitoring of the health status of wildlife in these protected areas, with a focus on lowland gorillas. Over the years, activities have been expanded to better characterize the interface between humans, animals and the environment in this extraordinary ecosystem.
Symbolic image defense against viruses
Vaccinations do not always live up to what we would want them to do – so far, anyway. But they are still invaluable for our health and life in our communities.
Symbol image; hand turns an equal and an unequal sign between the symbols for male and female gender
Men are more susceptible to a number of chronic infections, while women, in turn, are more likely to overreact to infections. The underlying reason and why it needs to be taken into account more in clinical practice in the future. Am I more likely to have a mild case of pneumonia or is it more likely to be life-threatening? What is my risk of side effects from COVID-19 vaccination? Do I belong to a group of people who are more likely to contract chronic viral hepatitis than others? The answers to these questions vary – depending on your sex and gender. Hospitalised for pneumonia, males are twice as likely as females to need to be transferred to intensive care (Source). Females, in turn, are more than twice as likely as males to suffer side effects from the COVID-19 vaccine. And chronic hepatitis B is more common among males than among females.
Since mid-May 2022, several countries where mpox/monkeypox is not endemic have reported an accumulation of infections with the monkeypox virus. Cases have also been diagnosed in Germany, as of May 2023 around 3700 infections were recorded. Researchers at the Helmholtz Centre for Infection Research (HZI) are contributing their expertise to assessing the current situation and informing the public.
Scientist in the zebrafish facility
On the World Day for Laboratory Animals April 24, 2023, special attention is paid to the use of animals for research and development of products for humans. In drug research, among other areas, extensive animal testing is a firmly prescribed part of the approval process for new drugs. However, a reduction in the number of laboratory animals is increasingly in sight due to new approaches. At the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), a site of the Helmholtz Centre for Infection Research (HZI) in collaboration with Saarland University, researchers are successfully developing alternative models and have already received awards for their work.

HZI in the media

Forscher sind der gefährlichen Krankheit auf die Spur gegangen, dabei machten sie eine erstaunliche Entdeckung.

Regional Heute

Neue Bakterienfamilie mit hohem pharmazeutischem Potenzial entdeckt ...


Urplötzlich sind sie da und können – wie das Coronavirus SARS-CoV-2 – große Epidemien auslösen: ...

Verband Deutscher Biologen e.V.

Infections with worms from the filarial group, also known as filariasis, can lead to river blindness and, if left untreated, to ...


Flussblindheit und Lymphatische Filariose besser bekämpfen ...

MTA Dialog

The Global Health Innovative Technology (GHIT) Fund has announced an investment of Y1.64bn ($10.8m) in four new projects aimed at ...

Yahoo! Finance