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A participant of the Future Day 2024 in a laboratory
News
Today, around 70 students from years 5 to 9 visited the Helmholtz Centre for Infection Research (HZI) in Braunschweig to get an idea of what it is like to work in a modern research facility. They got a taste of the world of science and its administration in ten scientific and two administrative departments.
25.04.2024
Bakteriophagen
News
The antimicrobial potential of CRISPR-Cas systems is promising, yet how to best design or implement CRISPR nucleases remains poorly understood. An international team led by the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg has now addressed this knowledge gap. The researchers conducted the first systematic interrogation of CRISPR antimicrobials using multidrug-resistant and hypervirulent bacteria as case studies, revealing wide variations in efficacy that could be predicted via high-throughput screening and machine learning. Their findings were published today in the journal Nucleic Acids Research.
25.04.2024
Vero6 cells (renal epithelial cells) infected with SARS-CoV-2
News
The so-called B cells are part of the immune system's memory. Their memories of previous infections or vaccinations provide the template for antibodies that have a protective effect the next time they come into contact with a pathogen. Researchers at TWINCORE, Centre for Clinical and Experimental Infection Research, have now been able to show that the combination of infection and subsequent vaccination in the case of the SARS-CoV-2 coronavirus even protects against future variants of the virus by the memory cells virtually predicting the future. The team describes how this works in the European Journal of Immunology. The TWINCORE is a joint institution of the Helmholtz Centre for Infection Research (HZI) in Braunschweig and Hannover Medical School (MHH).
25.04.2024
Group photo with Luka Cicin-Sain, Adhara Madhuri, Henrik Klimke
News
Leukemia is the most common cancer in children. Cancer treatment severely weakens the children's immune system and they can easily develop opportunistic infections. One of the most common causes of such complications is the cytomegalovirus (CMV) from the herpes virus family. The department “Viral Immunology” headed by Prof. Luka Cicin-Sain at the Helmholtz Centre for Infection Research (HZI) in Braunschweig is now investigating immunotherapy options against CMV. The project is enabled by a donation from the Günter Hansmeier Krebsstiftung in Braunschweig, which is funding the position of a doctoral researcher for three years.
15.04.2024
Three dimensional structure of the transport protein ECF-T.
News
Due to the progressive spread of antimicrobial resistance, clinically important antibiotics are increasingly losing their effectiveness. New active substances are urgently needed to counteract this development. In order to circumvent existing resistance, new drugs must address previously unused target structures within the pathogens. HIPS scientist Prof. Anna Hirsch has been able to identify one such target and successfully acquired a “Proof of Concept” grant of the European Research Council (ERC) to support the development of novel active substances.
02.04.2024
Zecke auf Hautoberfläche
News
The Crimean-Congo Haemorrhagic Fever virus (CCHFV), first described in 1944, is also spreading rapidly in Europe due to global warming and is included in the WHO list of infectious agents with epidemic or pandemic potential as a top priority. There are currently no therapeutic or preventative measures available against the disease, which is mainly transmitted by ticks and is fatal in 40 per cent of cases.
29.03.2024

HZI in the media

Das antimikrobielle Potenzial von CRISPR-Cas-Systemen ist vielversprechend. Allerdings ist noch wenig darüber bekannt, ...

26.04.2024
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Verband Deutscher Biologen e.V.

Credit: Nucleic Acids Research (2024). DOI: 10.1093/nar/gkae281

 

The antimicrobial potential of CRISPR-Cas systems is promising, yet how to ...

25.04.2024
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Phys.org

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Staatskanzlei

 

Ministerium für Wirtschaft, Innovation, Digitales und Energie

 

Ministerium der Finanzen und für ...

25.04.2024
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Saarland

Ein Promotionsprojekt am Helmholtz-Zentrum für Infektionsforschung (HZI) erforscht Immuntherapien gegen Cytomegalievirus (CMV)-Infektionen ...

23.04.2024
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Biermann Medizin

Un informe de la revista Science detalla cómo el cultivo de tabaco puede ocasionar que los chimpancés sean portadores de virus similares al ...

23.04.2024
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La República.pe

Tobacco farming is driving apes to seek unusual food source, brimming with pathogens ...

22.04.2024
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Science.org

Corona hat es gezeigt: Erreger kennen keine Landesgrenzen. Wie also kann die nächste Pandemie verhindert ...

17.04.2024
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MDR

Ein Promotionsprojekt am Braunschweiger Helmholtz-Zentrum für Infektionsforschung erforscht Immuntherapie von Cytomegalievirus-Infektionen ...

15.04.2024
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Ärzte Zeitung

Prof. Anna Hirsch vom Helmholtz-Institut für Pharmazeutische Forschung Saarland (HIPS) entwickelt mit ERC-Förderung ...

15.04.2024
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Health&Care Management

Biotechnologie-Studierende erforschen Alternativen zu Öl und Gas ...

11.04.2024
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sueddeutsche.de

Wissenschaftler beschreiben einen neuen Ansatz für Prävention und Therapie des Krim-Kongo-Fiebers in einer ...

04.04.2024
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Biermann Medizin

Joghurt ist gesund – sogar so gesund, dass Sie ihn am besten täglich zu sich nehmen ...

03.04.2024
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Focus Online

Researchers find how antibiotic treatments influence the microbiota, providing new strategies for preventing antibiotic-induced damage.

02.04.2024
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Drug Target Review

Das hauptsächlich von Zecken übertragene Krim-Kongo-Hämorrhagische-Fieber-Virus (CCHFV) breitet sich aufgrund der globalen Erwärmung auch ...

29.03.2024
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Neues Volksblatt

Researchers have identified how the tick-borne Crimean-Congo haemorrhagic fever virus enters our cells. The results are an important step ...

28.03.2024
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ScienceDaily