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Streptococcus pyogenes löst am häufigsten nekrotisierende Fasziitis aus.

News

Necrotising fasciitis (NF) is the most severe form of tissue death caused by bacteria. The bacterium Streptococcus pyogenes is one of the main causes of this disease. The infections take a rapid course and are associated with devastating consequences for the afflicted individuals ranging from severe necrosis to toxic shock. The disease is often fatal. However, if detected at an early stage, it can be cured by treatment with medication and removal of the afflicted tissue. Scientists from the Helmholtz Centre for Infection Research (HZI) recently discovered the crucial role and protective effect of pathogen-specific antibodies in the first stage of the Streptococcus infection. Accordingly, early clinical application of a cocktail of human immunoglobulin G containing such specific antibodies might prevent the manifestation of tissue necrosis and the progress of the disease. The study was completed in cooperation with clinicians from the University hospitals in Bergen (Norway), Gothenburg and Stockholm (Sweden) and Copenhagen (Denmark) and was recently published in the Journal of Infectious Diseases.

27.06.2018

HZI Campus

News

Infections continue to be amongst the main causes of death throughout the world. Individually customised prevention and therapies promise to open up new options for curing diseases. But what is the current status of the research throughout the world and what are the most urgent questions – from an ethical, social and economic point of view? Experts will discuss these issues from 21 to 23 June in Hannover.

05.06.2018

CiiM

HZI-Forscherin Susanne Häußler mit Bundesministerin Anja Karliczek und Minister Björn Thümler.

News

High-ranking visitors at the Helmholtz Centre for Infection Research (HZI) and the Hannover Medical School (MHH): Federal Minister of Research Anja Karliczek and Lower Saxony's Minister for Science and Culture Björn Thümler used their personal visit on 31 May 2018 to catch up on the state of modern infection research in Lower Saxony. They visited the study centre of the NAKO health study in Hannover, which is being coordinated by the HZI, and the TWINCORE, Centre for Experimental and Clinical Infection Research, an institution that is run jointly by the Helmholtz Centre for Infection Research in Braunschweig and the Hannover Medical School.

31.05.2018

HZI Campus

TWINCORE

News

30 young scientists came together from 16 – 20 April 2018 at Bayer in Berlin for the ENLIGHT-TEN summer school on translational research and medicines development. The summer school introduced the participants to the knowledge, philosophy and tools needed in translational research and medicine development, empowering them to make a difference in translational medicine. A faculty of 13 high profile professionals from Industry, Academia and Biotech introduced the basics of the medicines development process including real life case studies.

24.05.2018

HZI Campus

Eine neue intelligente Software kann zukünftig helfen, krankheitserregende Salmonellen-Stämme frühzeitig zu identifizieren.

News

A new machine learning tool that can detect whether emerging strains of the bacterium, Salmonella are more likely to cause dangerous bloodstream infections rather than food poisoning has been developed. The tool, created by a scientist at the Wellcome Sanger Institute and her collaborators at the University of Otago, New Zealand and the Helmholtz Institute for RNA-based Infection Research, a site of the Helmholtz Centre for Infection Research, Germany, greatly speeds up the process for identifying the genetic changes underlying new invasive types of Salmonella that are of public health concern.

23.05.2018

HIRI

v.l.n.r.: Dirk Heinz (HZI), Rolf Müller (HIPS), Anke Kaysser-Pyzalla (TU Braunschweig), Frieda Kage (TU Braunschweig), Daniel Todt (TWINCORE), Dieter Jahn (TU Braunschweig) und Hansjörg Hauser (HZI / Förderverein).

News

Numerous pathogens are capable of becoming resistant to medications, such as antibiotics, which allows them to protect themselves from the antibiotics and to spread vigorously. Moreover, many diseases cannot be treated sufficiently because there are no effective drugs available. The search for new drugs is very laborious and resource-consuming. Natural products, so-called secondary metabolites, that are produced by bacteria, fungi and plants are some interesting candidates in this context. Especially soil-dwelling myxobacteria produce a large variety of natural agents which they use to eliminate microbial competitors or enemies. This is the special field of natural product researcher Prof Rolf Müller. Honouring his outstanding research aimed at the discovery of microbial natural products mainly from myxobacteria, the German pharmacist has been awarded this year's Inhoffen Award, to be presented on 17 May. Müller directs the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), a branch site of the Helmholtz Centre for Infection Research (HZI) and the Saarland University.

09.05.2018

HZI Campus

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