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Der Virologe Luka Cicin-Sain erforscht SARS-CoV-2-neutralisierende Antikörper, die von der Technischen Universität Braunschweig und YUMAB isoliert wurden.

News

Neutralizing antibodies are the interceptors of our immune system. They bind precisely to pathogens and prevent them from entering our cells. After an infection, the immune system needs about two weeks to produce mature antibodies. In severe cases of Covid-19, the body's immune reaction often comes too late for the patient. One option for acute treatment would therefore be to administer antibodies to the patients that are immediately effective. Recent results of the CORAT Consortia, especially from the Helmholtz Centre for Infection Research (HZI) in cooperation with the Technische Universität Braunschweig and the company YUMAB, have led to a breakthrough in the development of fully human antibodies for immune therapies.

07.05.2020

HZI Campus

Story

The Pharmacokinetics/Pharmacodynamics unit (PK/PD unit) at the Helmholtz Centre for Infection Research (HZI) in Braunschweig investigates the potential of drug candidates against pathogens, using special testing procedures. If the candidates pass these stringent preclinical tests, they stand a chance of being shortlisted for further development towards clinical testing.

06.05.2020

HZI Campus

Illustration des Coronavirus SARS-CoV-2.

News

29.04.2020

How susceptible are small children to the new coronavirus? Tests on 500 LöwenKIDS are underway.

News

Currently, little is known about children and their susceptibility to the new coronavirus. It has been observed that young children have rarely presented with COVID-19 up to now. No specific investigations have been conducted as to how many children have already contracted the virus and overcome the infection without any remarkable symptoms. In a DZIF project, scientists now intend to investigate this with the help of “LoewenKIDS”.

28.04.2020

HZI Campus

TWINCORE

In der weltweit größten Substanz-Repurposing-Bank „ReFrame“ suchen Wissenschaftler nach Medikamenten gegen COVID-19.

News

Innovations based on proven active ingredients, new indications for established drugs – the principle of repurposing has often led to success in medicine. This is why it is also used against SARS-CoV-2: In order to quickly find a drug to treat COVID-19, this international research network is searching for substances that act against SARS-CoV-2 in the world's largest substance repurposing bank "ReFrame". The collection comprises around 14,000 approved drugs as well as active ingredients for which extensive safety data are already available with regard to their use in humans. Several laboratories in the USA, four in the UK and one each in China and Germany are involved in the search. "ReFrame" was established by Scripps Research, California, in 2018 with the support of the Bill & Melinda Gates Foundation.

24.04.2020

TWINCORE

Flagella that protrude from bacterial cells

News

Several whip-like appendages, called the flagella, protrude from the body of bacteria such as Salmonella Typhimurium. It has long been understood that the flagella are responsible for bacterial motility, which enables the directed movement of bacteria towards nutrients or an infection target site. In a recent publication in Nature Communications, researchers from the Centre for Structural Systems Biology (CSSB) in Hamburg and collaborators have demonstrated that flagella also promote bacterial adhesion and host cell invasion. The CSSB is a common initiative by nine northern German research institutions, including the Helmholtz Centre for Infection Research (HZI) in Braunschweig.

24.04.2020

CSSB

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transkript

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... fünf Teams durch, darunter PROTON vom Helmholtz-Zentrum für Infektionsforschung. Dieses entwickelt einen neuartigen Wirkstoff gegen ...

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Ad Hoc News

Vor allem durch die Coronapandemie sind Forschende des Helmholtz-Zentrums für Infektionsforschung in den vergangenen Jahren bundesweit bekannt geworden. Auf welche Themen die Einrichtung für die Zukunft setzt.

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Deutsches Ärzteblatt

... beschäftigt sich daneben unter dem Dach des Helmholtz Institutes für Pharmazeutische Forschung Saarland (HIPS) ...

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Biermann Medizin

... Ausbau von Produktions- und Vermarktungskapazitäten.

Das Helmholtz-Zentrum für Infektionsforschung HZI begrüßt den Erhalt der GMP- ...

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Bionity.COM

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