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iCAIR® consortium delivers first results on the way to inhalable drugs against SARS-CoV-2
In May 2020, the international consortium iCAIR® started a research project aimed at developing therapeutics against SARS-CoV-2. The Helmholtz Centre for Infection Research (HZI), which joined forces with the consortium's core team last year, is also closely involved in this project. The HZI researchers under the leadership of Prof. Ulrich Kalinke have expanded the iCAIR® outstanding talent pool: they boast a successful track record in antiviral drug research, in particular against human pathogenic RNA viruses, and have compound libraries as well as test models and primary virus isolates. In addition, a team from Fraunhofer ITMP led by Prof. Carsten Claussen and Dr. Ole Pless is on board as a temporary project partner. The iCAIR® research team already can report promising results, which were presented by iCAIR® coordinator Prof. Armin Braun and others at Fraunhofer ITEM's virtual workshop "Models of Lung Disease" in January.
08.04.2021
TWINCORE
Rasterelektronenmikroskopische Aufnahme von Mycobacterium tuberculosis
News
World Tuberculosis Day 2021: New drugs for old bugs
Every year, about 10 million people become infected with tuberculosis and 1.4 million die from it. This makes tuberculosis not only one of the most widespread infectious diseases, but also the deadliest. Similar to malaria or HIV, the prevalence of tuberculosis is strongly dependent on social factors; it is considered a classic disease of the poor. In addition to a lack of medical care, other problems hinder the containment of tuberculosis, such as antibiotic resistance and undesirable drug-drug interactions.
24.03.2021
Illustration
News
Putting pathogens on mute
The bacterium Pseudomonas aeruginosa is among the most common causes of pneumonia and poses a major challenge to hospitals worldwide. The treatment of infections with Pseudomonas aeruginosa is usually challenging because the bacterium forms so-called biofilms, which protect it from drugs. Dr Martin Empting and his team, in collaboration with several groups at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), have now developed an innovative method to disrupt the formation of these biofilms and thus facilitate the treatment of infections with Pseudomonas aeruginosa. The researchers have published their findings in the journal Advanced Science.
19.03.2021
HZI Campus
HIPS
Grafik Myelom-Zellen mit BCMA-Expression
News
Würzburg researchers track down resistance in CAR-T cell therapy
Therapeutically modified white blood cells hold great potential in the treatment of multiple myeloma, a malignant cancer of the bone marrow. However, they can lead to serious resistance in treated patients. In close cooperation, medical doctors and scientists from the University Hospital and the Helmholtz Institute for RNA-based Infection Research in Würzburg have now investigated the causes of this previously unexplained phenomenon. In the process, they uncovered a crucial resistance mechanism. The results were just published in the journal Nature Medicine.
11.03.2021
HIRI
Modell Antikörper
News
New Chance for Better Pandemic Response
An international research team of the Technische Universität Braunschweig and the Helmholtz Centre for Infection Research (HZI), led by the Department of Biotechnology of the TU Braunschweig, has reported on the development of special antibodies against SARS-CoV-2 in the journal Nature Communications. These antibodies prevent the viruses from entering host cells and were isolated from an antibody gene library that had already been produced from immune cells of healthy donors before the pandemic. The study shows how, in the future, active substances to previously unknown, emerging viruses can be produced very quickly without patient material.
11.03.2021
HZI Campus
News
CoVerage analyses lineage dynamics of SARS-CoV-2 variants
The CoVerage tool analyses the lineage dynamics of SARS-CoV-2 strains, i.e. determines how successfully which virus strain spreads. The web resource uses input from the Gisaid genome database. Gisaid is an international initiative that aims to make research data rapidly available to the public. Scientists from all over the world contribute genome sequences of viruses such as H1N1, influenza or SARS-CoV-2 to the database, thus providing a broad overview of mutations and their genetic differences. However, to predict the spread potential of these mutations, a simple count of incidences is not sufficient.
04.03.2021
HZI Campus

HZI in the media

An African monkey ate a rope squirrel and came down with mpox

says Livia Patrono, a veterinarian and disease ecologist at Helmholtz Institute for One Health in Greifswald, Germany. In 2012, an infected

24.02.2026
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Science News
Biosicherheit: Wenn Künstliche Intelligenz neuartige Viren liefert

... Dr. rer. nat. Jakob Wirbel vom Helmholtz-Zentrum für Infektionsforschung (Braunschweig). Das Experiment aus Stanford sei ...

20.02.2026
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Deutsches Ärzteblatt
Wie Bakterien ihre Zucker-Tarnkappe stricken: Neuer Ansatz gegen Resistenzen?

... unseres Immunsystems zu entziehen. Strukturbiologen des Helmholtz-Zentrums für Infektionsforschung (HZI) konnten nun mittels ...

18.02.2026
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Bionity.COM
Molecular 'knitting machine' for bacterial capsules mapped in 3D

of our immune system. Structural biologists at the Helmholtz Center for Infection Research (HZI) have now used cryo-electron microscopy to

16.02.2026
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Phys.org
Wohl von Feuerfußhörnchen übertragen: Was man über Ansteckung mit Mpox wissen muss

Was es mit Mpox – früher Affenpocken genannt – auf sich hat, welche Symptome erkrankte Personen haben und wie man sich anstecken kann.

13.02.2026
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Apotheken Umschau
Mpox transmission model sheds light on a medical mystery

Julia Port, research group leader at Germany's Helmholtz Center for Infection Research.

 

"Ongoing outbreaks—particularly those driven by

12.02.2026
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Medical Xpress
Möglicher Ursprung des Affenpockenvirus entdeckt

... Livia Patrono, laut einer Mitteilung des beteiligten Helmholtz-Instituts für One Health (HIOH): Denn dadurch ...

12.02.2026
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n-tv
Neue Strahlenklinik soll Anfang 2027 fertig sein

... für den Neubau der Klinik für Strahlentherapie Würzburg sowie für das Helmholtz-Institut für RNA-basierte ...

12.02.2026
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Main-Post - Karlstadt
Fire-footed rope squirrels identified as a natural reservoir for monkeypox virus

Project

 

Researchers at the Helmholtz Institute for One Health (HIOH), a site of the Helmholtz Centre for Infection Research (HZI), together

11.02.2026
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NewsBreak
Viromed Medical AG reports promising study results for PulmoPlas® in intensive care unit ventilator-associated pneumonia patients

by Prof. Hortense Slevogt, Hannover Medical School, and Helmholtz Centre for Infection Research, shows that the treatment with PulmoPlas®

10.02.2026
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Biotech Investments
Immunkrankheiten im Blut aufspüren

... der Medizinischen Hochschule Hannover und des Helmholtz-Zentrums für Infektionsforschung. „Unsere Methode erfordert nur einen ...

10.02.2026
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Health Capital
Technologietransfer für Corallopyronin A mit Phyton Biotech erfolgreich abgeschlossen

Fermentation und Aufreinigung, wurde ebenfalls am HZI in der Arbeitsgruppe von Prof. Marc Stadler, stellvertretender ...

06.02.2026
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juraforum.de

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