Dr. Mathias Müsken

Dr. Mathias Müsken
Forschungsgruppenleiter
+49 531 6181-4009

Dr. Mathias Müsken

Mathias Müsken studierte von 2000-2006 Molekulare Biotechnologie an der Universität Bielefeld. Schon in seiner Diplomarbeit lag sein Fokus auf dem Gebiet der Mikrobiologie speziell der Untersuchung des Proteoms von Corynebacterium jeikeium. Als ERASMUS-Student hatte er zudem die Möglichkeit zu einem Aufenthalt an der Königlichen Technischen Hochschule in Stockholm, Schweden. 2006, im Gründungsjahr des HZIs, begann er mit seiner Promotion in Braunschweig, die ihn noch einmal für ein halbes Jahr nach Stockholm führte, dieses Mal an das Karolinska Institut. Die Mikroskopie war zu diesem Zeitpunkt bereits zentraler Bestandteil seines Wirkens. Die im Rahmen seiner Doktorarbeit etablierten mikroskopischen Verfahren zur quantitativen Analyse von bakteriellen Biofilmen begleiten ihn auch heute noch. Im Anschluss war er als Postdoc in der Abteilung „Molekulare Bakteriologie“ am Twincore in Hannover tätig und versuchte, altbewährte Antibiotika für die Behandlung von Biofilmen zu optimieren und neue Anti-Biofilm Wirkstoffe in großangelegten Screens zu identifizieren. 2017 wechselte er zurück an das HZI in die „Zentrale Einheit für Mikroskopie“. Diese Arbeitsgruppe übernahm Mathias Müsken im Jahr 2021 und ist seitdem verantwortlich für die Leitung der Plattform. Neben der langjährigen Erfahrung auf dem Gebiet der Lebendzell-Mikroskopie ist er auch der Experte für die angebotenen, elektronenmikroskopischen Verfahren.

Publikationen
Rieper F., Wittmann J., Bunk B., ..., Müsken M., Ziehr H., ... , Korf I.H.E., Jahn D. (2025)
Correction: Systematic bacteriophage selection for the lysis of multiple Pseudomonas aeruginosa strains (Frontiers in Cellular and Infection Microbiology, (2025), 15, (1597009), 10.3389/fcimb.2025.1597009)
Front.Cell.Infect.Microbiol., 15
DOI: 10.3389/fcimb.2025.1650832 HZI-Repositorium PubMed
Ehling S., Peh E., Oltmanns H., Meißner J., Kittler S., Puff C., Verspohl J., Müsken M., ... , Plötz M., Volk A.V. (2025)
Bacteriophage and Fusidic Acid Have Synergistic Effect Against Meticillin-Resistant Staphylococcus pseudintermedius in ExVivo Canine Dermis Model
Vet.Dermatol.
DOI: 10.1111/vde.70030 HZI-Repositorium PubMed
Linz B., Tegtmeyer N., Afroz S., Müsken M., Fox J.G., Haesebrouck F., Kao M.C., ... , Sticht H., Backert S. (2025)
Molecular characterization of four Helicobacter cetorum strains from dolphins compared to human Helicobacter pylori
Gut Microbes, 17 (1)
DOI: 10.1080/19490976.2025.2557982 HZI-Repositorium PubMed
Musher D.M., Müsken M., Hicks M.J., McGee L., Beall B. (2025)
Encapsulation of Disease-Causing and Commensal Mitis Group Non-Pneumococcal Streptococci
Pathogens, 14 (9)
DOI: 10.3390/pathogens14090876 HZI-Repositorium PubMed
Engelhardt F., Turnbull K., Gür M., Müsken M., Preusse M., ... , Häussler S., Roghanian M. (2025)
(p)ppGpp imposes graded transcriptional changes to impair motility and promote antibiotic tolerance in biofilms
npj Biofilms and Microbiomes, 11 (1)
DOI: 10.1038/s41522-025-00795-7 HZI-Repositorium PubMed
Rieper F., Wittmann J., Bunk B., Spröer C., Häfner M., Willy C., Müsken M., Ziehr H., ... , Korf I.H.E., Jahn D. (2025)
Systematic bacteriophage selection for the lysis of multiple Pseudomonas aeruginosa strains
Front.Cell.Infect.Microbiol., 15
DOI: 10.3389/fcimb.2025.1597009 HZI-Repositorium PubMed
Dalponte A., Filor V., Lübke-Becker A., Fulde M., Alter T., ... , Müsken M., Bäumer W. (2025)
Characterization and purification of Pseudomonas aeruginosa phages for the treatment of canine infections
BMC Microbiology, 25 (1)
DOI: 10.1186/s12866-025-04005-4 HZI-Repositorium PubMed
Plenge M., Schnepel N., Müsken M., Rohde J., Goethe R., Breves G., ... , Mazzuoli-Weber G., Benz P. (2025)
Development and characterization of a 2D porcine colonic organoid model for studying intestinal physiology and barrier function
PLoS ONE, 20 (5 May)
DOI: 10.1371/journal.pone.0312989 HZI-Repositorium PubMed
Broich L., Wullenkord H., Osman M.K., Fu Y., Müsken M., Reuther P., ... , Brönstrup M., Sieben C. (2025)
Single influenza A viruses induce nanoscale cellular reprogramming at the virus-cell interface
Nature Communications, 16 (1)
DOI: 10.1038/s41467-025-58935-8 HZI-Repositorium PubMed
Deschner F., Mostert D., Daniel J.M., Voltz A., Schneider D.C., Khangholi N., Bartel J., Pessanha de Carvalho L., Brauer M., Gorelik T.E., Kleeberg C., Risch T., Haeckl F.P.J., Herraiz Benitez L., Andreas A., Kany A.M., Jezequel G., Hofer W., Müsken M., Held J., Bischoff M., Seemann R., Brötz-Oesterhelt H., Schneider T., Sieber S., ... , Müller R., Herrmann J. (2025)
Natural products chlorotonils exert a complex antibacterial mechanism and address multiple targets
Cell Chemical Biology, 32 (4)
DOI: 10.1016/j.chembiol.2025.03.005 HZI-Repositorium PubMed
Thiemann M., Zimmermann M., Diederich C., Zhan H., Lebedev M., Pletz J., Baumgarten J., Handke M., Müsken M., Breinbauer R., Krasteva-Christ G., Zanin E., Empting M., Schiedel M., ... , Kunick C., Blankenfeldt W. (2025)
From Bones to Bugs: Structure-Based Development of Raloxifene-Derived Pathoblockers That Inhibit Pyocyanin Production in Pseudomonas aeruginosa
J.Med.Chem.
DOI: 10.1021/acs.jmedchem.4c03065 HZI-Repositorium PubMed
Bouheraoua S., Cleeves S., Preusse M., Müsken M., Braubach P., Fuchs M., Falk C., ... , Sewald K., Häussler S. (2025)
Establishment and characterization of persistent Pseudomonas aeruginosa infections in air-liquid interface cultures of human airway epithelial cells
Infect.Immun., 93 (3)
DOI: 10.1128/iai.00603-24 HZI-Repositorium PubMed
Zierke L., Mourad R., Kohler T.P., Müsken M., Hammerschmidt S. (2025)
Influence of the polysaccharide capsule on virulence and fitness of Klebsiella pneumoniae
Frontiers in Microbiology, 16
DOI: 10.3389/fmicb.2025.1450984 HZI-Repositorium PubMed
Dyksma S., Neumann-Schaal M., Müsken M., Pester M. (2025)
Desulfosporosinus paludis sp. nov., an acidotolerant sulphate-reducing bacterium isolated from moderately acidic fen soil
Int.J Syst.Evol.Microbiol., 75 (1)
DOI: 10.1099/ijsem.0.006648 HZI-Repositorium PubMed
Lehky M., Moonian T., Michel T., Junker D., Müsken M., Strömpl J., Nübling P., Neumann F., Krumbholz A., Krause G., Schneiderhan-Marra N., ... , van den Heuvel J., Strengert M. (2025)
A novel method for recombinant mammalian-expressed S-HBsAg virus-like particle production for assembly status analysis and improved anti-HBs serology
Protein Sci., 34 (1)
DOI: 10.1002/pro.5251 HZI-Repositorium PubMed
Ayala-Garcia P., Herrero-Gomez I., Jimenez-Guerrero I., Otto V., Moreno-de Castro N., Müsken M., Jänsch L., Van Ham M., Vinardell J.M., Lopez-Baena F.J., Ollero F.J., ... , Perez-Montano F., Borrero-de Acuna J.M. (2024)
Extracellular Vesicle-Driven Crosstalk between Legume Plants and Rhizobia: The Peribacteroid Space of Symbiosomes as a Protein Trafficking Interface
J.Proteome Res., 24 (1)
DOI: 10.1021/acs.jproteome.4c00444 HZI-Repositorium PubMed
Rackow B., Rolland C., Mohnen I., Wittmann J., Müsken M., ... , Overmann J., Frunzke J. (2024)
Isolation and characterization of the new Streptomyces phages Kamino, Geonosis, Abafar, and Scarif infecting a broad range of host species
Microbiol.Spectr.
DOI: 10.1128/spectrum.00663-24 HZI-Repositorium PubMed
Schum D., Elsen F.A.V., Ruddell S., Schorpp K., Junca H., Müsken M., Chen S.Y., Fiedler M.K., Pickl T., Pieper D.H., Hadian K., ... , Zacharias M., Sieber S.A. (2024)
Screening Privileged Alkyl Guanidinium Motifs under Host-Mimicking Conditions Reveals a Novel Antibiotic with an Unconventional Mode of Action
JACS Au
DOI: 10.1021/jacsau.4c00449 HZI-Repositorium
Osbelt L., Almasi E.D.H., Wende M., Kienesberger S., Voltz A., Lesker T.R., Muthukumarasamy U., Knischewski N., Nordmann E., Bielecka A.A., Giralt-Zuniga M., Kaganovitch E., Kühne C., Baier C., Pietsch M., Müsken M., Greweling-Pils M.C., Breinbauer R., Flieger A., Schlüter D., Müller R., Erhardt M., ... , Zechner E.L., Strowig T. (2024)
Klebsiella oxytoca inhibits Salmonella infection through multiple microbiota-context-dependent mechanisms
Nat.Microbiol.
DOI: 10.1038/s41564-024-01710-0 HZI-Repositorium PubMed
Schmid N., Brandt D., Walasek C., Rolland C., Wittmann J., Fischer D., Müsken M., ... , Kalinowski J., Thormann K. (2024)
An autonomous plasmid as an inovirus phage satellite
Appl.Environ.Microbiol.
DOI: 10.1128/aem.00246-24 HZI-Repositorium PubMed
Sharafutdinov I., Harrer A., Müsken M., Rottner K., Sticht H., Täger C., Naumann M., ... , Tegtmeyer N., Backert S. (2024)
Cortactin-dependent control of Par1b-regulated epithelial cell polarity in Helicobacter infection
Cell Insight, 3 (3)
DOI: 10.1016/j.cellin.2024.100161 HZI-Repositorium PubMed
Zeng H., Stadler M., Decock C., Matasyoh J.C., Schrey H., Müsken M. (2024)
Discovery of novel secondary metabolites from the basidiomycete Lentinus cf. sajor-caju and their inhibitory effects on Staphylococcus aureus biofilms
Fitoterapia, 175
DOI: 10.1016/j.fitote.2024.105904 HZI-Repositorium PubMed
Krueger J., Preusse M., Oswaldo Gomez N., Frommeyer Y.N., Doberenz S., Lorenz A., Kordes A., Grobe S., Müsken M., Depledge D.P., Svensson S.L., Weiss S., Kaever V., Pich A., Sharma C.M., ... , Ignatova Z., H+ñussler S. (2024)
tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen Pseudomonas aeruginosa
Proc Natl Acad Sci U S A, 121 (11)
DOI: 10.1073/pnas.2312874121 HZI-Repositorium PubMed
Ayala-Garcia P., Jiminez-Guerrero I., Müsken M., Ollero F.J., Borrero-de Acuna J.M., Perez-Montano F. (2024)
Isolation of Rhizobial Extracellular Membrane Vesicles from Bacteroids
Methods in molecular biology (Clifton, N.J.) (15)
DOI: 10.1007/978-1-0716-3617-6_15 PubMed
Ayala-Garcia P., Moreno-de Castro N., Jimenez-Guerrero I., Müsken M., Arce-Rodriguez A., ... , Perez-Montano F., Borrero-de Acuna J.M. (2024)
Isolation, Quantification, and Visualization of Extracellular Membrane Vesicles in Rhizobia Under Free-Living Conditions
Methods in molecular biology (Clifton, N.J.), 2751 (14)
DOI: 10.1007/978-1-0716-3617-6_14 PubMed
Kretschmer M., Müller J., Henke P., Otto V., Rodriguez A.A., Müsken M., Jahn D., Borrero-de Acuna J.M., ... , Neumann-Schaal M., Wegner A. (2023)
Isolation and Quantification of Bacterial Membrane Vesicles for Quantitative Metabolic Studies Using Mammalian Cell Cultures
Cells, 12 (23)
DOI: 10.3390/cells12232674 PubMed
Brunetti A.E., Lyra M.L., Bauermeister A., Bunk B., Boedeker C., Müsken M., Neto F.C., Mendonca J.N., Caraballo-Rodriguez A.M., Melo W.G.P., Pupo M.T., Haddad C.F.B., Cabrera G.M., ... , Overmann J., Lopes N.P. (2023)
Host macrocyclic acylcarnitines mediate symbiotic interactions between frogs and their skin microbiome
iScience, 26 (11)
DOI: 10.1016/j.isci.2023.108109 HZI-Repositorium PubMed
Vieira S., Huber K.J., Geppert A., Wolf J., Neumann-Schaal M., ... , Müsken M., Overmann J. (2023)
Baekduia alba sp. nov., a novel representative of the order Solirubrobacterales isolated from temperate grassland soil
Int.J.Syst.Evol.Microbiol., 73 (5)
DOI: 10.1099/ijsem.0.005918 HZI-Repositorium
Bublitz A., Brauer M., Wagner S., Hofer W., Müsken M., Deschner F., Lesker T.R., Neumann-Schaal M., Paul L., Nübel U., Bartel J., Kany A.M., Zühlke D., Bernecker S., Jansen R., Sievers S., Riedel K., Herrmann J., Müller R., ... , Fuchs T.M., Strowig T. (2023)
The natural product chlorotonil A preserves colonization resistance and prevents relapsing Clostridioides difficile infection
Cell Host.Microbe
DOI: 10.1016/j.chom.2023.04.003 HZI-Repositorium PubMed
Alpers K., Vatareck E., Gröbe L., Müsken M., Scharfe M., ... , Häußler S., Tomasch J. (2023)
Transcriptome Dynamics of Pseudomonas aeruginosa during Transition from Overlapping To Non-Overlapping Cell Cycles
mSystems.
DOI: 10.1128/msystems.01130-22 HZI-Repositorium PubMed
Karagöz M.S., Ünal C.M., Mayer B.E., Müsken M., Borrero-de Acuna J.M., Steinert M. (2022)
Legionella pneumophila PPIase Mip Interacts with the Bacterial Proteins SspB, Lpc2061, and FlaA and Promotes Flagellation
Infect.Immun., 90 (11)
DOI: 10.1128/iai.00276-22 HZI-Repositorium PubMed
Lang J.C., Seiß E.A., Moldovan A., Müsken M., Sauerwein T., Fraunholz M., Müller A.J., ... , Goldmann O., Medina E. (2022)
A Photoconvertible Reporter System for Bacterial Metabolic Activity Reveals That Staphylococcus aureus Enters a Dormant-Like State to Persist within Macrophages
MBio.
DOI: 10.1128/mbio.02316-22 HZI-Repositorium PubMed
Pira H., Risdian C., Müsken M., Schupp P.J., Wink J. (2022)
Winogradskyella luteola- sp.nov., Erythrobacter ani sp. nov., and Erythrobacter crassostrea sp.nov., isolated from the hemolymph of the Pacific Oyster Crassostrea gigas
Arch.Microbiol., 204 (8)
DOI: 10.1007/s00203-022-03099-y HZI-Repositorium PubMed
Kage F., Döring H., Mietkowska M., Schaks M., Grüner F., Stahnke S., Steffen A., Müsken M., ... , Stradal T.E.B., Rottner K. (2022)
Lamellipodia-like actin networks in cells lacking WAVE regulatory complex
J Cell Sci, 135 (15)
DOI: 10.1242/jcs.260364 HZI-Repositorium PubMed
Vieira S., Huber K.J., Geppert A., Wolf J., Neumann-Schaal M., Luckner M., Wanner G., ... , Müsken M., Overmann J. (2022)
Capillimicrobium parvum gen. nov., sp. nov., a novel representative of Capillimicrobiaceae fam. nov. within the order Solirubrobacterales, isolated from a grassland soil
Int.J.Syst.Evol.Microbiol., 72 (8)
DOI: 10.1099/ijsem.0.005508 HZI-Repositorium PubMed
Pira H., Risdian C., Müsken M., Schupp P.J., Wink J. (2022)
Photobacterium arenosum WH24, Isolated from the Gill of Pacific Oyster Crassostrea gigas from the North Sea of Germany: Co-cultivation and Prediction of Virulence
Curr.Microbiol., 79 (8)
DOI: 10.1007/s00284-022-02909-2 HZI-Repositorium PubMed
Aghapour M., Tulen C.B.M., Abdi Sarabi M., Weinert S., Müsken M., Relja B., van Schooten F.J., Jeron A., Braun-Dullaeus R., ... , Remels A.H., Bruder D. (2022)
Cigarette Smoke Extract Disturbs Mitochondria-Regulated Airway Epithelial Cell Responses to Pneumococci
Cells, 11 (11)
DOI: 10.3390/cells11111771 HZI-Repositorium PubMed
Tareen S., Risdian C., Müsken M., Wink J. (2022)
Qipengyuania pacifica sp. nov., a Novel Carotenoid-Producing Marine Bacterium of the Family Erythrobacteraceae, Isolated from Sponge (Demospongiae), and Antimicrobial Potential of Its Crude Extract
Diversity, 14 (4)
DOI: 10.3390/d14040295 HZI-Repositorium
Jahn K., Shumba P., Quach P., Müsken M., Wesche J., Greinacher A., Rajagopal L., ... , Hammerschmidt S., Siemens N. (2022)
Group B Streptococcal Hemolytic Pigment Impairs Platelet Function in a Two-Step Process
Cells, 11 (10)
DOI: 10.3390/cells11101637 HZI-Repositorium PubMed
Sharafutdinov I., Tegtmeyer N., Müsken M., Backert S. (2022)
Campylobacter jejuni Serine Protease HtrA Induces Paracellular Transmigration of Microbiota across Polarized Intestinal Epithelial Cells
Biomolecules, 12 (4)
DOI: 10.3390/biom12040521 HZI-Repositorium PubMed
Kopenhagen A., Ramming I., Camp B., Hammerschmidt S., Fulde M., Müsken M., ... , Steinert M., Bergmann S. (2022)
Streptococcus pneumoniae Affects Endothelial Cell Migration in Microfluidic Circulation
Frontiers in Microbiology, 13
DOI: 10.3389/fmicb.2022.852036 HZI-Repositorium PubMed
Bense S., Witte J., Preuße M., Koska M., Pezoldt L., Dröge A., Hartmann O., Müsken M., Schulze J., Fiebig T., Bähre H., Felgner S., ... , Pich A., Häußler S. (2022)
Pseudomonas aeruginosa post-translational responses to elevated c-di-GMP levels
Molecular Microbiology
DOI: 10.1111/mmi.14902 HZI-Repositorium PubMed
Pira H., Risdian C., Müsken M., Schupp P.J., Wink J. (2022)
Pacificimonas pallium sp. nov., an Isolated Bacterium from the Mantle of Pacific Oyster Crassostrea gigas in Germany, and Prediction of One-Carbon Metabolism
Diversity, 14 (3)
DOI: 10.3390/d14030181 HZI-Repositorium
Tareen S., Risdian C., Müsken M., Wink J. (2021)
Alteriqipengyuania abyssalis sp. Nov., a novel member of the class alphaproteobacteria isolated from sponge, and emended description of the genus alteriqipengyuania
Diversity, 13 (12)
DOI: 10.3390/d13120670 HZI-Repositorium
Pira H., Risdian C., Kämpfer P., Müsken M., Schupp P.J., Wink J. (2021)
Zooshikella harenae sp. Nov., isolated from pacific Oyster Crassostrea gigas, and establishment of zooshikella ganghwensis subsp. marina subsp. nov. and Zooshikella ganghwensis subsp. Ganghwensis subsp. nov
Diversity, 13 (12)
DOI: 10.3390/d13120641 HZI-Repositorium
Malik M.N.H., Waqas S.F.H., Zeitvogel J., Cheng J., Geffers R., Gouda Z.A., Elsaman A.M., Radwan A.R., Schefzyk M., Braubach P., Auber B., Olmer R., Müsken M., Roesner L.M., Gerold G., Schuchardt S., Merkert S., Martin U., Meissner F., ... , Werfel T., Pessler F. (2021)
Congenital deficiency reveals critical role of ISG15 in skin homeostasis
J.Clin.Invest
DOI: 10.1172/JCI141573 HZI-Repositorium PubMed
Stahnke S., Döring H., Kusch C., De Gorter D.J.J., Dütting S., Guledani A., Pleines I., Schnoor M., Sixt M., Geffers R., Rohde M., Müsken M., Kage F., Steffen A., Faix J., Nieswandt B., ... , Rottner K., Stradal T.E.B. (2021)
Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion
Curr.Biol., 31 (5 / May)
DOI: 10.1016/j.cub.2021.02.043 HZI-Repositorium PubMed
Hasenzahl M., Müsken M., Mertsch S., Schrader S., Reichl S. (2021)
Cell sheet technology: Influence of culture conditions on in vitro-cultivated corneal stromal tissue for regenerative therapies of the ocular surface
J.Biomed.Mater.Res.Part B Appl.Biomater.
DOI: 10.1002/jbm.b.34808 HZI-Repositorium PubMed
Donnert M., Elsheikh S., Arce-Rodriguez A., Pawar V., Braubach P., Jonigk D., Haverich A., Weiss S., ... , Müsken M., Häußler S. (2020)
Targeting bioenergetics is key to counteracting the drug-tolerant state of biofilm-grown bacteria
PLoS.Pathog., 16 (12)
DOI: 10.1371/journal.ppat.1009126 HZI-Repositorium PubMed
Schulz V., Schulz A., Klamke M., Preissler K., Sabino-Pinto J., Müsken M., Schlüpmann M., Heldt L., Kamprad F., Enss J., Schweinsberg M., Virgo J., Rau H., Veith M., Lötters S., Wagner N., ... , Steinfartz S., Vences M. (2020)
Batrachochytrium salamandrivorans in the ruhr district, germany: History, distribution, decline dynamics and disease symptoms of the salamander plague
Salamandra, 56 (3)
DOI: - HZI-Repositorium
Thöming J.G., Tomasch J., Preusse M., Koska M., Grahl N., Pohl S., Willger S.D., Kaever V., ... , Müsken M., Häußler S. (2020)
Parallel evolutionary paths to produce more than one Pseudomonas aeruginosa biofilm phenotype
NPJ.Biofilms.Microbiomes., 6 (1)
DOI: 10.1038/s41522-019-0113-6 HZI-Repositorium PubMed
Goldmann O., Cern A., Müsken M., Rohde M., Weiss W., ... , Barenholz Y., Medina E. (2019)
Liposomal mupirocin holds promise for systemic treatment of invasive Staphylococcus aureus infections
J.Control Release, 316
DOI: 10.1016/j.jconrel.2019.11.007 PubMed
de Groot C., Müsken M., Bleckmann M., Ebensen T., Guzmán C.A., Müller-Goymann C.C. (2019)
Novel colloidal associations of soyasaponins and lipid components (DPPC, cholesterol) as potential adjuvants for vaccines
Vaccine, 37 (35)
DOI: 10.1016/j.vaccine.2019.07.020 PubMed
de Groot C., Müsken M., Müller-Goymann C.C. (2019)
The bidesmosidic triterpene saponins hederacoside C and ginsenoside Rb1 exhibit low affinity to cholesterol in liposomal membranes
J.Drug Deliv.Sci.Technol., 53 (October)
DOI: 10.1016/j.jddst.2019.101127
Döring M., Blees H., Koller N., Tischer-Zimmermann S., Müsken M., Henrich F., Becker J., Grabski E., Wang J., Janssen H., Zuschratter W., Neefjes J., Klawonn F., Eiz-Vesper B., ... , Tampe R., Kalinke U. (2019)
Modulation of TAP-dependent antigen compartmentalization during human monocyte-to-DC differentiation
Blood Adv., 3 (6)
DOI: 10.1182/bloodadvances.2018027268 HZI-Repositorium PubMed
Müsken M., Pawar V., Schwebs T., Bähre H., Felgner S., ... , Weiss S., Häußler S. (2018)
Breaking the vicious cycle of antibiotic killing and regrowth of biofilm-residing Pseudomonas aeruginosa
Antimicrob.Agents Chemother., 62 (12)
DOI: 10.1128/AAC.01635-18 HZI-Repositorium PubMed
Dolati S., Kage F., Mueller J., Müsken M., Kirchner M., Dittmar G., Sixt M., ... , Rottner K., Falcke M. (2018)
On the relation between filament density, force generation and protrusion rate in mesenchymal cell motility
Mol.Biol.Cell, 29 (22)
DOI: 10.1091/mbc.E18-02-0082 HZI-Repositorium PubMed
de Groot C., Müsken M., Müller-Goymann C.C. (2018)
Novel Colloidal Microstructures of [beta]-Escin and the Liposomal Components Cholesterol and DPPC
Planta Med., 84 (16)
DOI: 10.1055/a-0624-2706 PubMed
Müsken M., Klimmek K., Sauer-Heilborn A., Donnert M., Sedlacek L., ... , Suerbaum S., Häußler S. (2017)
Towards individualized diagnostics of biofilm-associated infections: a case study
NPJ.Biofilms.Microbiomes., 3 (22)
DOI: 10.1038/s41522-017-0030-5 HZI-Repositorium
van Duuren J.B.J.H., Müsken M., Karge B., Tomasch J., Wittmann C., ... , Häußler S., Brönstrup M. (2017)
Use of Single-Frequency Impedance Spectroscopy to Characterize the Growth Dynamics of Biofilm Formation in Pseudomonas aeruginosa
Sci.Rep., 7 (1)
DOI: 10.1038/s41598-017-05273-5 HZI-Repositorium PubMed
Müsken M. (2016)
Bacterial biofilms: Endless horror? Basics, new findings, and treatment options
Nieren- Hochdruckkr., 45 (4)
DOI: - PubMed
Kommerein N., Stumpp S.N., Musken M., Ehlert N., Winkel A., Häußler S., Behrens P., ... , Buettner F.F.R., Stiesch M. (2017)
An oral multispecies biofilm model for high content screening applications
PLoS ONE, 12 (3)
DOI: 10.1371/journal.pone.0173973 HZI-Repositorium PubMed
Xu S., Ducroux A., Ponnurangam A., Vieyres G., Franz S., Musken M., Zillinger T., Malassa A., Ewald E., Hornung V., Barchet W., Häußler S., ... , Pietschmann T., Goffinet C. (2016)
cGAS-Mediated Innate Immunity Spreads Intercellularly through HIV-1 Env-Induced Membrane Fusion Sites
Cell Host.Microbe, 20 (4)
DOI: 10.1016/j.chom.2016.09.003
Ghanbari A., Dehghany J., Schwebs T., Musken M., Häußler S., Meyer-Hermann M. (2016)
Inoculation density and nutrient level determine the formation of mushroom-shaped structures in Pseudomonas aeruginosa biofilms
Sci Rep., 6
DOI: 10.1038/srep32097 HZI-Repositorium PubMed
Vidigal P.G., Müsken M., Becker K.A., Häußler S., Wingender J., Steinmann Eike, Kehrmann J., Gulbins E., Buer J., ... , Rath P.M., Steinmann J. (2014)
Effects of Green Tea Compound Epigallocatechin-3-Gallate against Stenotrophomonas maltophilia Infection and Biofilm
PLoS ONE, 9 (4)
DOI: 10.1371/journal.pone.0092876 HZI-Repositorium PubMed
Bielecki P., Komor U., Bielecka A., Musken M., Puchalka J., Pletz M.W., Ballmann M., Martins dos Santos V, ... , Weiss Siegfried, Häußler Susanne (2013)
Ex vivo transcriptional profiling reveals a common set of genes important for the adaptation of Pseudomonas aeruginosa to chronically infected host sites
Environmental Microbiology, 15 (2)
DOI: 10.1111/1462-2920.12024 HZI-Repositorium PubMed
Pustelny C., Brouwer S., Musken M., Bielecka A., Dotsch A., ... , Nimtz Manfred, Häußler Susanne (2013)
The peptide chain release factor methyltransferase PrmC is essential for pathogenicity and environmental adaptation of Pseudomonas aeruginosa PA14
Environmental Microbiology, 15 (2)
DOI: 10.1111/1462-2920.12040 HZI-Repositorium PubMed
Storz M.P., Maurer C.K., Zimmer C., Wagner N., Brengel C., De Jong J.C., Lucas S., Musken M., Häußler Susanne, ... , Steinbach A., Hartmann Rolf W. (2012)
Validation of PqsD as an Anti-biofilm Target in Pseudomonas aeruginosa
Journal of the American Chemical Society, 134 (39)
Selezska K., Kazmierczak M., Musken M., Garbe J., Schobert M., Häußler Susanne*, Wiehlmann L., ... , Rohde C., Sikorski J. (2012)
Pseudomonas aeruginosa population structure revisited under environmental focus: impact of water quality and phage pressure
Environmental Microbiology, 14 (8)
Lu C., Kirsch B., Zimmer C., De Jong J.C., Henn C., Maurer C.K., Müsken M., Häußler Susanne*, ... , Steinbach A., Hartmann Rolf W. (2012)
Discovery of antagonists of PqsR, a key player in 2-alkyl-4-quinolone- dependent quorum sensing in Pseudomonas aeruginosa
Chemistry and Biology, 19 (3)
DOI: 10.1016/j.chembiol.2012.01.015 HZI-Repositorium PubMed
Zaoui C., Overhage J., Lons D., Zimmermann A., Musken M., Bielecki P., Pustelny C., Becker T., ... , Nimtz Manfred, Häußler Susanne (2012)
An orphan sensor kinase controls quinolone signal production via MexT in Pseudomonas aeruginosa
Molecular Microbiology, 83 (3)
Wei Q., Tarighi S., Dotsch A., Häußler Susanne*, Musken M., Wright V.J., Camara M., Williams P., Haenen S., Boerjan B., Bogaerts A., Vierstraete E., Verleyen P., Schoofs L., Willaert R., De Groote V, Michiels J., Vercammen K., ... , Crabbe A., Cornelis P. (2011)
Phenotypic and Genome-Wide Analysis of an Antibiotic-Resistant Small Colony Variant (SCV) of Pseudomonas aeruginosa
PLoS ONE, 6 (12)
DOI: 10.1371/journal.pone.0029276 HZI-Repositorium PubMed
Schmidt J., Musken M., Becker T., Magnowska Z., Bertinetti D., Moller S., Zimmermann B., Herberg F.W., ... , Jansch L., Häußler Susanne* (2011)
The Pseudomonas aeruginosa Chemotaxis Methyltransferase CheR1 Impacts on Bacterial Surface Sampling
PLoS ONE, 6 (3)
DOI: 10.1371/journal.pone.0018184 HZI-Repositorium PubMed
Pommerenke C., Musken M., Becker T., Dotsch A., Klawonn Frank*, Häußler Susanne* (2010)
Global genotype-phenotype correlations in Pseudomonas aeruginosa
PLoS Pathogens, 6 (8)
DOI: 10.1371/journal.ppat.1001074 HZI-Repositorium PubMed
Müsken M., Di Fiore S., Römling U., Häußler Susanne* (2010)
A 96-well-plate-based optical method for the quantitative and qualitative evaluation of Pseudomonas aeruginosa biofilm formation and its application to susceptibility testing
Nature Protocols, 5 (8)
Musken M., Di Fiore S., Dotsch A., Fischer R., Häußler Susanne* (2010)
Genetic determinants of Pseudomonas aeruginosa biofilm establishment
Microbiology, 156 (Pt 2)

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