Author count: 13
Schöner T.A., Vogel V., Venczel M., Knoth K., Kamm W., Paehler T., Louit G., Teran I.T., Mundinger P., Marker A., Loos P., ... , Hittinger M., Lehr C.M.
(2024)
Biorelevant subcutaneous in vitro test predicts the release of human and fast acting insulin formulations
Int.J.Pharm., 655
Author count: 4
Floroiu A., Loretz B., Krämer J., Lehr C.M.
(2024)
Drug solubility in biorelevant media in the context of an inhalation-based biopharmaceutics classification system (iBCS)
European Journal of Pharmaceutics and Biopharmaceutics, 197 (April 2024)
Author count: 7
Subramaniam S., Joyce P., Ogunniyi A.D., Dube A., Sampson S.L., ... , Lehr C.M., Prestidge C.A.
(2024)
Minimum Information for Conducting and Reporting In Vitro Intracellular Infection Assays
ACS infectious diseases, 10 (2)
Author count: 8
Aparicio-Blanco J., Vishwakarma N., Lehr C.M., Prestidge C.A., Thomas N., Roberts R.J., ... , Thorn C.R., Melero A.
(2024)
Antibiotic resistance and tolerance : What can drug delivery do against this global threat?
Drug Deliv.Transl.Res.
Author count: 4
Chatzi Memet B., Demirpolat E., Yildirim T., Aydin O.
(2024)
Development of Polymer-Based Nanoparticles for the Reduction of Melittin Toxicity
IFMBE Proceedings (6)
Author count: 11
Brand M., Ritzmann F., Kattler K., Milasius D., Yao Y., Herr C., Kirsch S.H., Müller R., Yildiz D., ... , Bals R., Beisswenger C.
(2024)
Biochemical and transcriptomic evaluation of a 3D lung organoid platform for pre-clinical testing of active substances targeting senescence
Respiratory research, 25 (1)
Author count: 11
Fu C., Liu Y., Walt C., Rasheed S., Bader C.D., Lukat P., Neuber M., Haeckl F.P.J., Blankenfeldt W., ... , Kalinina O.V., Müller R.
(2024)
Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins
Nature Communications, 15 (1)
Author count: 21
Konstantinovic J., Kany A.M., Alhayek A., Abdelsamie A.S., Sikandar A., Voos K., Yao Y., Andreas A., Shafiei R., Loretz B., Schönauer E., Bals R., Brandstetter H., Hartmann R.W., Ducho C., Lehr C.M., Beisswenger C., Müller R., Rox K., ... , Haupenthal J., Hirsch A.K.
(2023)
Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections
ACS Cent.Sci., 9 (12)
Author count: 8
Nnamani P.O., Diovu E.O., Peter I.E., Onwuka A.M., Ogbuanwu C.V., Abonyi O.E., ... , Loretz B., Lehr C.M.
(2023)
Anti-Inflammatory and Antinociceptive Activity of Herbal Lipospheres of Pentaclethra macrophylla (Fabaceae) Stem Bark Extract
Process., 11 (9)
Author count: 4
Nnamani P., Kenechukwu F., Okoye C., Attama A.
(2024)
Surface-engineered Oral Sub-micron Particles and Topical Microgels Matrixed with Transcutol-HP/Capra hircus Composite for Amplification of Piroxicam Delivery and Anti-inflammatory Activity
Lett.Appl.NanoBioSci., 13 (1)
Author count: 7
Nesterkina M., Vashchenko O., Vashchenko P., Lisetski L., Kravchenko I., ... , Hirsch K.H., Lehr C.M.
(2023)
Thermoresponsive cholesteric liquid -
Eur.J.Pharm.Biopharm., 191
Author count: 5
Bali A., Kamal M.A.M., Mulla G., Loretz B., Lehr C.M.
(2023)
Functional Materials to Overcome Bacterial Barriers and Models to Advance Their Development
Adv.Funct.Mater.
Author count: 10
Liu Y., Ashmawy S., Latta L., Weiss A.V., Kiefer A.F., Nasr S., Loretz B., Hirsch A.K.H., ... , Lee S., Lehr C.M.
(2023)
pH-Responsive Dynaplexes as Potent Apoptosis Inductors by Intracellular Delivery of Survivin siRNA
Biomacromolecules, 24 (8)
Author count: 5
Gvozdovskyy I.A., Kachurak Y.M., Vashchenko P.V., Kravchenko I.A., Mykytyuk Z.M.
(2023)
Liquid crystal sensors for detection of volatile organic compounds: comparative effects of vapor absorption and temperature on the phase state of the sensor material
Funct.Mater., 30 (2)
Author count: 9
Berwanger A., Stein S.C., Kany A.M., Gartner M., Loretz B., Lehr C.M., Hirsch A.K.H., ... , Schulz T.F., Empting M.
(2023)
Disrupting Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Latent Replication with a Small Molecule Inhibitor
J.Med.Chem., 66 (15)
Author count: 8
Wu Y., Zoller B.G.E., Kamal M.A.M., Hotop S.K., Lehr C.M., Brönstrup M., ... , Dersch P., Empting M.
(2023)
Establishment of an In Bacterio assay for the Assessment of Carbon Storage Regulator A (CsrA) inhibitors
Chembiochem.
Author count: 8
Arrua E.C., Hartwig O., Loretz B., Murgia X., Ho D.K., Bastiat G., ... , Lehr C.M., Salomon C.J.
(2023)
Formulation of benznidazole-lipid nanocapsules: Drug release, permeability, biocompatibility, and stability studies
Int.J.Pharm., 642 (July 2023)
Author count: 3
Gabelmann A., Lehr C.M., Grohganz H.
(2023)
Preparation of Co-Amorphous Levofloxacin Systems for Pulmonary Application
Pharmaceutics., 15 (6)
Author count: 6
Barthold S., Kunschke N., Murgia X., Loretz B., Carvalho-Wodarz C.S., Lehr C.M.
(2023)
Overview of Inhaled Nanopharmaceuticals
J.Aerosol Med.Pulm.Drug Deliv., 36 (3)
Author count: 10
Aliyazdi S., Frisch S., Hidalgo A., Frank N., Krug D., Müller R., Schaefer U.F., Vogt T., ... , Loretz B., Lehr C.M.
(2023)
3D bioprinting of E. coli MG1655 biofilms on human lung epithelial cells for building complex in vitro infection models
Biofabrication., 15 (3)
Author count: 12
Nnamani P., Nnadi O., Odo A., Abimibola V., Ugwu A., Ibezim E., Ogbonna J.D., Onoja S., Ayogu E., Adikwu M., ... , Lehr C.M., Attama A.
(2022)
Gentamicin nanogel films based on Carrageenan-Prosopis africana for improved wound healing
Precis.Nanomed., 5 (2)
Author count: 5
Sousa C.F., Becker R.A., Lehr C.M., Kalinina O.V., Hub J.S.
(2023)
Simulated Tempering-Enhanced Umbrella Sampling Improves Convergence of Free Energy Calculations of Drug Membrane Permeation
J.Chem.Theory Comput.
Author count: 11
Heinrich E., Hartwig O., Walt C., Kardani A., Koch M., Jahromi L.P., Hoppstädter J., Kiemer A.K., Loretz B., ... , Lehr C.M., Fuhrmann G.
(2023)
Cell-Derived Vesicles for Antibiotic Delivery :
Small
Author count: 16
Carius P., Jungmann A., Bechtel M., Grißmer A., Boese A., Gasparoni G., Salhab A., Seipelt R., Urbschat K., Richter C., Meier C., Bojkova D., Cinatl J., Walter J., ... , Schneider-Daum N., Lehr C.M.
(2023)
A Monoclonal Human Alveolar Epithelial Cell Line ("Arlo") with Pronounced Barrier Function for Studying Drug Permeability and Viral Infections
Adv.Sci., 10 (8)
Author count: 13
Huck B., Hidalgo A., Waldow F., Schwudke D., Gaede K.I., Feldmann C., Carius P., Autilio C., Perez-Gil J., Schwarzkopf K., Murgia X., ... , Loretz B., Lehr C.-M.
(2023)
Systematic Analysis of Composition, Interfacial Performance and Effects of Pulmonary Surfactant Preparations on Cellular Uptake and Cytotoxicity of Aerosolized Nanomaterials
Small Science, 1 (12)
Author count: 8
Kliesch L., Delandre S., Gabelmann A., Koch M., Schulze K., Guzman C.A., ... , Loretz B., Lehr C.M.
(2022)
Lipid -
Pharmaceutics, 14 (12)
Author count: 10
Rautaniemi K., John T., Richter M., Huck B.C., Zini J., Loretz B., Lehr C.M., Vuorimaa-Laukkanen E., ... , Lisitsyna E., Laaksonen T.
(2022)
Intracellular Dynamics of Extracellular Vesicles by Segmented Trajectory Analysis
Anal.Chem., 94 (51)
Author count: 14
Lee S., Nasr S., Rasheed S., Liu Y., Hartwig O., Kaya C., Boese A., Koch M., Herrmann J., Müller R., Loretz B., Buhler E., ... , Hirsch A.K.H., Lehr C.M.
(2022)
Proteoid biodynamers for safe mRNA transfection via pH-responsive nanorods enabling endosomal escape
J.Control.Release, 353
Author count: 8
Sousa C.F., Kamal M.A.M., Richter R., Elamaldeniya K., Hartmann R.W., Empting M., ... , Lehr C.M., Kalinina O.V.
(2022)
Modeling the Effect of Hydrophobicity on the Passive Permeation of Solutes across a Bacterial Model Membrane
J.Chem.Inf.Model., 62 (20)
Author count: 7
Arrua E.C., Hartwig O., Loretz B., Goicoechea H., Murgia X., ... , Lehr C.M., Salomon C.J.
(2022)
Improving the oral delivery of benznidazole nanoparticles by optimizing the formulation parameters through a design of experiment and optimization strategy
Colloids Surf.B Biointerfaces, 217 (Sept. 22)
Author count: 18
Sengupta A., Roldan N., Kiener M., Froment L., Raggi G., Imler T., de Maddalena L., Rapet A., May T., Carius P., Schneider-Daum N., Lehr C.M., Kruithof-de Julio M., Geiser T., Marti T.M., Stucki J.D., ... , Hobi N., Guenat O.T.
(2022)
A New Immortalized Human Alveolar Epithelial Cell Model to Study Lung Injury and Toxicity on a Breathing Lung-On-Chip System
Front Toxicol., 4
Author count: 3
Niranjan Dhanasekar N., Thiyagarajan D., Bhatia D.
(2022)
DNA Origami in the Quest for Membrane Piercing
Chem.Asian J.
Author count: 8
Mehanny M., Boese A., Bornamehr B., Hoppstädter J., Presser V., Kiemer A.K., ... , Lehr C.M., Fuhrmann G.
(2022)
Spray-dried pneumococcal membrane vesicles are promising candidates for pulmonary immunization
Int.J.Pharm., 621
Author count: 8
Hartwig O., Loretz B., Nougarede A., Jary D., Sulpice E., Gidrol X., ... , Navarro F., Lehr C.M.
(2022)
Leaky gut model of the human intestinal mucosa for testing siRNA-based nanomedicine targeting JAK1
J Control Release, 345
Author count: 20
Huck B.C., Thiyagarajan D., Bali A., Boese A., Besecke K.F.W., Hozsa C., Gieseler R.K., Furch M., Carvalho-Wodarz C., Waldow F., Schwudke D., Metelkina O., Titz A., Huwer H., Schwarzkopf K., Hoppstädter J., Kiemer A.K., Koch M., ... , Loretz B., Lehr C.M.
(2022)
Nano-in-Microparticles for Aerosol Delivery of Antibiotic-Loaded, Fucose-Derivatized, and Macrophage-Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery
Adv.Healthc.Mater.
Author count: 7
Huck B.C., Murgia X., Frisch S., Hittinger M., Hidalgo A., ... , Loretz B., Lehr C.M.
(2022)
Models using native tracheobronchial mucus in the context of pulmonary drug delivery research: Composition, structure and barrier properties
Adv.Drug Deliv.Rev., 183 (April 2022)
Author count: 7
Metelkina O., Huck B., O'Connor J.S., Koch M., Manz A., ... , Lehr C.M., Titz A.
(2022)
Targeting extracellular lectins of Pseudomonas aeruginosa with glycomimetic liposomes
J.Mater.Chem.B, 10 (4)
Author count: 12
Horstmann J.C., Laric A., Boese A., Yildiz D., Röhrig T., Empting M., Frank N., Krug D., Müller R., Schneider-Daum N., ... , De Souza Carvalho-Wodarz C., Lehr C.M.
(2021)
Transferring Microclusters of P. aeruginosa Biofilms to the Air-Liquid Interface of Bronchial Epithelial Cells for Repeated Deposition of Aerosolized Tobramycin
ACS Infect.Dis.
Author count: 6
Nasr S.S., Lee S., Thiyagarajan D., Boese A., Loretz B., Lehr C.M.
(2021)
Co-delivery of mRNA and pDNA using thermally stabilized coacervate-based core-shell nanosystems
Pharmaceutics, 13 (11)
Author count: 8
Sousa C.F., Coimbra J.T.S., Richter R., Morais-Cabral J.H., Ramos M.J., Lehr C.M., ... , Fernandes P.A., Gameiro P.
(2021)
Exploring the permeation of fluoroquinolone metalloantibiotics across outer membrane porins by combining molecular dynamics simulations and a porin-mimetic in vitro model
Biochim.Biophys.Acta Biomembr., 1864 (3)
Author count: 4
Schneider-Daum N., Hittinger M., Murgia X., Lehr C.-M.
(2019)
Cellular and non-cellular barriers to particle transport across the lungs
NanoScience and Technology (7)
Author count: 7
Carius P., Dubois A., Ajdarirad M., Artzy-Schnirman A., Sznitman J., ... , Schneider-Daum N., Lehr C.M.
(2021)
PerfuPul-A Versatile Perfusable Platform to Assess Permeability and Barrier Function of Air Exposed Pulmonary Epithelia
Front Bioeng.Biotechnol., 9
Author count: 8
Mehanny M., Kroniger T., Koch M., Hoppstädter J., Becher D., Kiemer A.K., ... , Lehr C.M., Fuhrmann G.
(2021)
Yields and Immunomodulatory Effects of Pneumococcal Membrane Vesicles Differ with the Bacterial Growth Phase
Advanced Healthcare Materials
Author count: 5
Luengo J., Schneider M., Schneider A.M., Lehr C.M., Schaefer U.F.
(2021)
Human skin permeation enhancement using plga nanoparticles is mediated by local ph changes
Pharmaceutics, 13 (10)
Author count: 3
Lehr C.M., Yeo L., Sznitman J.
(2021)
Editorial: Innovative In Vitro Models for Pulmonary Physiology and Drug Delivery in Health and Disease
Frontiers in Bioengineering and Biotechnology, 9
Author count: 9
Fahier J., Vukosavljevic B., Kinder L., Florin H., Goossens J.F., Windbergs M., Siepmann F., ... , Siepmann J., Muschert S.
(2021)
Towards a better understanding of verapamil release from kollicoat sr:Ir coated pellets using non-invasive analytical tools
Pharmaceutics, 13 (10)
Author count: 14
Richter R., Kamal M.A.M., Koch M., Niebuur B.J., Huber A.L., Goes A., Volz C., Vergalli J., Kraus T., Müller R., Schneider-Daum N., Fuhrmann G., ... , Pagès J.M., Lehr C.M.
(2021)
An Outer Membrane Vesicle-based Permeation Assay (OMPA) for Assessing Bacterial Bioavailability
Adv.Healthc.Mater.
Author count: 6
Primavessy D., Metz J., Schnur S., Schneider M., Lehr C.M., Hittinger M.
(2021)
Pulmonary in vitro instruments for the replacement of animal experiments
Eur.J.Pharm.Biopharm.
Author count: 54
Miethke M., Pieroni M., Weber T., Brönstrup M., Hammann P., Halby L., Arimondo P.B., Glaser P., Aigle B., Bode H.B., Moreira R., Li Y., Luzhetskyy A., Medema M.H., Pernodet J.L., Stadler M., Tormo J.R., Genilloud O., Truman A.W., Weissman K.J., Takano E., Sabatini S., Stegmann E., Brötz-Oesterhelt H., Wohlleben W., Seemann M., Empting M., Hirsch A.K.H., Loretz B., Lehr C.M., Titz A., Herrmann J., Jaeger T., Alt S., Hesterkamp T., Winterhalter M., Schiefer A., Pfarr K., Hoerauf A., Graz H., Graz M., Lindvall M., Ramurthy S., Karlen A., van Dongen M., Petkovic H., Keller A., Peyrane F., Donadio S., Fraisse L., Piddock L.J.V., Gilbert I.H., ... , Moser H.E., Müller R.
(2021)
Towards the sustainable discovery and development of new antibiotics
Nat.Rev.Chem.
Author count: 36
Singh B., Abdelgawad M.E., Ali Z., Bailey J., Budyn E., Civita P., Clift M.J.D., Connelly J.T., Constant S., Hittinger M., Kandarova H., Kearns V.R., Kiuru T., Kostrzewski T., Kress S., Durban V.M., Lehr C.M., McMillan H., Metz J.K., Monteban V., Movia D., Neto C., Owen C., Paasonen L., Palmer K.A., Pilkington G.J., Pilkington K., Prina-Mello A., Roper C., Sheard J., Smith S., Turner J.E., Roy I., Tutty M.A., ... , Velliou E., Wilkinson J.M.
(2021)
Towards More Predictive, Physiological and Animal-free In Vitro Models: Advances in Cell and Tissue Culture 2020 Conference Proceedings
Altern.Lab Anim
Author count: 6
Hartwig O., Shetab Boushehri M.A., Shalaby K.S., Loretz B., Lamprecht A., Lehr C.M.
(2021)
Drug delivery to the inflamed intestinal mucosa - targeting technologies and human cell culture models for better therapies of IBD
Advanced Drug Delivery Reviews, 175 (August 2021)
Author count: 13
Thiyagarajan D., Huck B., Nothdurft B., Koch M., Rudolph D., Rutschmann M., Feldmann C., Hozsa C., Furch M., Besecke K.F.W., Gieseler R.K., ... , Loretz B., Lehr C.M.
(2021)
Spray-dried lactose-leucine microparticles for pulmonary delivery of antimycobacterial nanopharmaceuticals
Drug Deliv.Transl.Res, 11 (4)
Author count: 5
Loretz B., Oh Y.K., Hudson S., Gu Z., Lehr C.M.
(2021)
Drug delivery for fighting infectious diseases: a global perspective
Drug Deliv.Transl.Res, 11 (4)
Author count: 9
Juntke J., Murgia X., Günday Türeli N., Türeli A.E., Thorn C.R., Schneider M., Schneider-Daum N., ... , De Souza Carvalho-Wodarz C., Lehr C.M.
(2021)
Testing of aerosolized ciprofloxacin nanocarriers on cystic fibrosis airway cells infected with P. aeruginosa biofilms
Drug Deliv.Transl.Res.
Author count: 7
Arrua E.C., Hartwig O., Ho D.K., Loretz B., Murgia X., ... , Salomon C.J., Lehr C.M.
(2021)
Surfactant-Free Glibenclamide Nanoparticles: Formulation, Characterization and Evaluation of Interactions with Biological Barriers
Pharm.Res.
Author count: 6
Thorn C.R., Carvalho-Wodarz C.D.S., Horstmann J.C., Lehr C.M., Prestidge C.A., Thomas N.
(2021)
Tobramycin Liquid Crystal Nanoparticles Eradicate Cystic Fibrosis-Related Pseudomonas aeruginosa Biofilms
Small, 17 (24)
Author count: 7
Horstmann J.C., Thorn C.R., Carius P., Graef F., Murgia X., ... , De Souza Carvalho-Wodarz C., Lehr C.M.
(2021)
A Custom-Made Device for Reproducibly Depositing Pre-metered Doses of Nebulized Drugs on Pulmonary Cells in vitro
Front.Bioeng.Biotechnol., 9 (April 2021)
Author count: 8
Huck B.C., Hartwig O., Biehl A., Schwarzkopf K., Wagner C., Loretz B., ... , Murgia X., Lehr C.M.
(2019)
Macro- And Microrheological Properties of Mucus Surrogates in Comparison to Native Intestinal and Pulmonary Mucus
Biomacromolecules, 20 (9)
Author count: 20
Duran V., Grabski E., Hozsa C., Becker J., Yasar H., Monteiro J.T., Costa B., Koller N., Lueder Y., Wiegmann B., Brandes G., Kaever V., Lehr C.M., Lepenies B., Tampé R., Förster R., Bosnjak B., Furch M., ... , Graalmann T., Kalinke U.
(2021)
Fucosylated lipid nanocarriers loaded with antibiotics efficiently inhibit mycobacterial propagation in human myeloid cells
J.Control Release, 334
Author count: 2
Richter R., Lehr C.M.
(2021)
Extracellular vesicles as novel assay tools to study cellular interactions of anti-infective compounds - a perspective
Adv.Drug Deliv.Rev., 173 (June 2021)
Author count: 2
Jahromi L.P., Fuhrmann G.
(2021)
Bacterial extracellular vesicles: Understanding biology promotes applications as nanopharmaceuticals
Adv.Drug Deliv.Rev., 173 (June)
Author count: 3
Mehanny M., Lehr C.M., Fuhrmann G.
(2021)
Extracellular vesicles as antigen carriers for novel vaccination avenues
Adv.Drug Deliv.Rev., 173 (6)
Author count: 26
Schütz C., Ho D.K., Hamed M.M., Abdelsamie A.S., Röhrig T., Herr C., Kany A.M., Rox K., Schmelz S., Siebenbürger L., Wirth M., Börger C., Yahiaoui S., Bals R., Scrima A., Blankenfeldt W., Horstmann J.C., Christmann R., Murgia X., Koch M., Berwanger A., Loretz B., Hirsch A.K.H., Hartmann R.W., ... , Lehr C.M., Empting M.
(2021)
A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms
Adv.Sci.
Author count: 7
Nnamani P.O., Ugwu A.A., Nnadi O.H., Kenechukwu F.C., Ofokansi K.C., ... , Attama A.A., Lehr C.M.
(2021)
Formulation and evaluation of transdermal nanogel for delivery of artemether
Drug Deliv.Transl.Res.
Author count: 10
Frisch S., Boese A., Huck B., Horstmann J.C., Ho D.K., Schwarzkopf K., Murgia X., Loretz B., ... , De Souza Carvalho-Wodarz C., Lehr C.M.
(2021)
A pulmonary mucus surrogate for investigating antibiotic permeation and activity against Pseudomonas aeruginosa biofilms
J.Antimicrob.Chemother., 76 (6)
Author count: 4
Ropponen H.K., Richter R., Hirsch A.K.H., Lehr C.M.
(2021)
Mastering the Gram-Negative Bacterial Barrier - Chemical Approaches to Increase Bacterial Bioavailability of Antibiotics
Adv.Drug Deliv.Rev., 172
Author count: 3
Trousil J., Aryal S., Fuhrmann G.
(2021)
Biogenic and biomimetic nanocarrier-based interventions: focus on intracellular infections
Nanomedicine.(Lond), 16 (9)
Author count: 6
Nnamani P.O., Kenechukwu F.C., Asogwa F.O., Momoh M.A., Lehr C.M., Attama A.A.
(2020)
Novel anti-ulcer phytosomal formulation of ethanol extract of pentaclethra macrophylla stem-bark
Trop.J.Nat.Prod.Res., 4 (8)
Author count: 12
Selo M.A., Delmas A.S., Springer L., Zoufal V., Sake J.A., Clerkin C.G., Huwer H., Schneider-Daum N., Lehr C.M., Nickel S., ... , Langer O., Ehrhardt C.
(2020)
Tobacco Smoke and Inhaled Drugs Alter Expression and Activity of Multidrug Resistance-Associated Protein-1 (MRP1) in Human Distal Lung Epithelial Cells in vitro
Front.Bioeng.Biotechnol., 8
Author count: 6
Ferreira A.R., Teixeira C., Sousa C.F., Bessa L.J., Gomes P., Gameiro P.
(2021)
How insertion of a single tryptophan in the N-terminus of a cecropin a-melittin hybrid peptide changes its antimicrobial and biophysical profile
Membr., 11 (1)
Author count: 6
García-Mouton C., Hidalgo A., Arroyo R., Echaide M., Cruz A., Pérez-Gil J.
(2021)
Pulmonary Surfactant and Drug Delivery: An Interface-Assisted Carrier to Deliver Surfactant Protein SP-D Into the Airways
Front.Bioeng.Biotechnol., 8
Author count: 12
Zamprogno P., Wüthrich S., Achenbach S., Thoma G., Stucki J.D., Hobi N., Schneider-Daum N., Lehr C.M., Huwer H., Geiser T., ... , Schmid R.A., Guenat O.T.
(2021)
Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane
Commun.Biolog., 4 (1)
Author count: 10
Metz J.K., Wiegand B., Schnur S., Knoth K., Schneider-Daum N., Groß H., Croston G., Reinheimer T.M., ... , Lehr C.M., Hittinger M.
(2021)
Modulating the Barrier Function of Human Alveolar Epithelial (hAELVi) Cell Monolayers as a Model of Inflammation
Altern.Lab Anim, 48 (5-6)
Author count: 10
Knoth K., Zäh R.K., Veldung B., Burgio D., Wiegand B., Smola H., Bock U., Lehr C.M., ... , Hittinger M., Groß H.
(2021)
Development and evaluation of a quality control system based on transdermal electrical resistance for skin barrier function in vitro
Skin Res.Technol.
Author count: 7
Hering S., Schäuble N., Buck T.M., Loretz B., Rillmann T., ... , Stieneker F., Lehr C.M.
(2021)
Analysis and optimization of two film-coated tablet production processes by computer simulation: A case study
Process., 9 (1)
Author count: 5
Ladaycia A., Loretz B., Passirani C., Lehr C.M., Lepeltier E.
(2021)
Microbiota and cancer: In vitro and in vivo models to evaluate nanomedicines
Adv.Drug Deliv.Rev., 170 (March 2021)
Author count: 18
Richter R., Kamal M.A.M., Garcia-Rivera M.A., Kaspar J., Junk M., Elgaher W.A.M., Srikakulam S.K., Gress A., Beckmann A., Grißmer A., Meier C., Vielhaber M., Kalinina O., Hirsch A.K.H., Hartmann R.W., Brönstrup M., ... , Schneider-Daum N., Lehr C.M.
(2020)
A hydrogel-based in vitro assay for the fast prediction of antibiotic accumulation in Gram-negative bacteria
Mater.Today Bio, 8
Author count: 10
Christmann R., Ho D.K., Wilzopolski J., Lee S., Koch M., Loretz B., Vogt T., Bäumer W., ... , Schaefer U.F., Lehr C.M.
(2020)
Tofacitinib loaded squalenyl nanoparticles for targeted follicular delivery in inflammatory skin diseases
Pharmaceutics, 12 (12)
Author count: 10
Hidalgo A., Garcia-Mouton C., Autilio C., Carravilla P., Orellana G., Islam M.N., Bhattacharya J., Bhattacharya S., ... , Cruz A., Pérez-Gil J.
(2020)
Pulmonary surfactant and drug delivery: Vehiculization, release and targeting of surfactant/tacrolimus formulations
J.Control Release, 329
Author count: 6
Montefusco-Pereira C.V., Carvalho-Wodarz C.S., Seeger J., Kloft C., Michelet R., Lehr C.M.
(2020)
Decoding (patho-)physiology of the lung by advanced in vitro models for developing novel anti-infectives therapies
Drug Discov.Today, 26 (1)
Author count: 10
Zamprogno P., Wuethrich S., Achenbach S., Stucki J.D., Hobi N., Schneider-Daum N., Lehr C.M., Huwer H., ... , Schmid R.A., Guenat O.T.
(2019)
New generation of air-blood barrier model: A lung-on-chip with a stretchable biological membrane
Author count: 4
Fuhrmann G., Loretz B., Schneider-Daum N., Lehr C.M.
(2021)
Biobarriers 2018
Eur.J Pharm.Biopharm., 158 (January 2021)
Author count: 11
Ho D.K., Christmann R., Murgia X., De Rossi C., Frisch S., Koch M., Schaefer U.F., Loretz B., Desmaele D., ... , Couvreur P., Lehr C.M.
(2020)
Synthesis and Biopharmaceutical Characterization of Amphiphilic Squalenyl Derivative Based Versatile Drug Delivery Platform
Front.Chem., 8
Author count: 5
Lababidi N., Montefusco-Pereira C.V., De Souza Carvalho-Wodarz C., Lehr C.M., Schneider M.
(2020)
Spray-dried multidrug particles for pulmonary co-delivery of antibiotics with N-acetylcysteine and curcumin-loaded PLGA-nanoparticles
Eur.J.Pharm.Biopharm., 157 (December)
Author count: 4
Carius P., Horstmann J.C., De Souza Carvalho-Wodarz C., Lehr C.M.
(2021)
Disease Models: Lung Models for Testing Drugs Against Inflammation and Infection
Handb.Exp.Pharmacol., 265 (1)
Author count: 14
Wiest J., Kehrein J., Saedtler M., Schilling K., Cataldi E., Sotriffer C.A., Holzgrabe U., Rasmussen T., Böttcher B., Cronin-Golomb M., Lehmann M., Jung N., ... , Windbergs M., Meinel L.
(2020)
Controlling Supramolecular Structures of Drugs by Light
Mol.Pharm., 17 (2)
Author count: 4
Schiller S., Hanefeld A., Schneider M., Lehr C.M.
(2020)
Towards a Continuous Manufacturing Process of Protein-Loaded Polymeric Nanoparticle Powders
AAPS PharmSciTech, 21 (7)
Author count: 11
Murgia X., Kany A.M., Herr C., Ho D.K., De Rossi C., Bals R., Lehr C.M., Hirsch A.K.H., Hartmann R.W., ... , Empting M., Röhrig T.
(2020)
Micro-rheological properties of lung homogenates correlate with infection severity in a mouse model of Pseudomonas aeruginosa lung infection
Sci.Rep., 10 (1)
Author count: 5
Ho D.K., De Rossi C., Loretz B., Murgia X., Lehr C.M.
(2020)
Itaconic acid increases the efficacy of tobramycin against Pseudomonas aeruginosa biofilms
Pharmaceutics, 12 (8)
Author count: 9
Montefusco-Pereira C.V., Horstmann J.C., Ebensen T., Beisswenger C., Bals R., Guzmán C.A., Schneider-Daum N., ... , Carvalho-Wodarz C.S., Lehr C.M.
(2020)
P. aeruginosa Infected 3D Co-Culture of Bronchial Epithelial Cells and Macrophages at Air-Liquid Interface for Preclinical Evaluation of Anti-Infectives
J.Vis.Exp. (160)
Author count: 15
Ho D.K., Murgia X., De Rossi C., Christmann R., Hüfner de Mello Martins A.G., Koch M., Andreas A., Herrmann J., Müller R., Empting M., Hartmann W., Desmaele D., Loretz B., ... , Couvreru P., Lehr C.M.
(2020)
Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and Alkylquinolone Quorum Sensing Inhibitor to Eradicate P. aeruginosa Biofilm Infections
Angew.Chem.Int.Ed Engl., 59 (26)
Author count: 7
Leonard F., Srinivasan S., Liu X., Collnot E.M., Ferrari M., ... , Lehr C.M., Godin B.
(2020)
Design and in vitro characterization of multistage silicon-PLGA budesonide particles for inflammatory bowel disease
Eur.J.Pharm.Biopharm., 151 (June)
Author count: 3
Jung N., Vukosavljevic B., Windbergs M.
(2018)
Raman spectroscopy in skin research and dermal drug delivery
(17)
Author count: 12
Guo X., Luo S., Amidani D., Rivetti C., Pieraccini G., Pioselli B., Catinella S., Murgia X., Salomone F., Xu Y., ... , Dong Y., Sun B.
(2020)
In vitro characterization and in vivo comparison of the pulmonary outcomes of Poractant alfa and Calsurf in ventilated preterm rabbits
PLoS ONE, 15 (3)
Author count: 3
Artzy-Schnirman A., Lehr C.M., Sznitman J.
(2020)
Advancing human in vitro pulmonary disease models in preclinical research: opportunities for lung-on-chips
Expert Opin.Drug Deliv., 17 (5)
Author count: 8
Lee S., Kaya C., Jang H., Koch M., Loretz B., Buhler E., ... , Lehr C.M., Hirsch A.K.H.
(2020)
PH-Dependent morphology and optical properties of lysine-derived molecular biodynamers
Mater.Chem.Front., 4 (3)
Author count: 4
Mehanny M., Koch M., Lehr C.M., Fuhrmann G.
(2020)
Streptococcal Extracellular Membrane Vesicles Are Rapidly Internalized by Immune Cells and Alter Their Cytokine Release
Front.Immunol., 11 (Feb)
Author count: 10
Metz J.K., Scharnowske L., Hans F., Schnur S., Knoth K., Zimmer H., Limberger M., Gross H., ... , Lehr C.M., Hittinger M.
(2020)
Safety assessment of excipients (SAFE) for orally inhaled drug products
ALTEX., 37 (2)
Author count: 12
Montefusco-Pereira C.V., Formicola B., Goes A., Re F., Marrano C.A., Mantegazza F., Carvalho-Wodarz C., Fuhrmann G., Caneva E., Nicotra F., ... , Lehr C.M., Russo L.
(2020)
Coupling quaternary ammonium surfactants to the surface of liposomes improves both antibacterial efficacy and host cell biocompatibility
Eur.J.Pharm.Biopharm., 149 (April)
Author count: 9
Nord A., Linner R., Salomone F., Bianco F., Ricci F., Murgia X., Schlun M., ... , Cunha-Goncalves D., Perez-de-Sa V.
(2020)
Lung deposition of nebulized surfactant in newborn piglets: Nasal CPAP vs Nasal IPPV
Pediatr.Pulmonol., 55 (2)
Author count: 13
Anversa Dimer F., De Souza Carvalho-Wodarz C., Goes A., Cirnski K., Herrmann J., Schmitt V., Pätzold L., Abed N., Rossi C., Bischoff M., Couvreur P., ... , Müller R., Lehr C.
(2020)
PLGA nanocapsules improve the delivery of clarithromycin to kill intracellular Staphylococcus aureus and Mycobacterium abscessus
Nanomedicine., 24
Author count: 6
Frank J., Richter M., De Rossi C., Lehr C.M., Fuhrmann K., Fuhrmann G.
(2019)
Author Correction: Extracellular vesicles protect glucuronidase model enzymes during freeze-drying (Scientific Reports, (2018), 8, 1, (12377), 10.1038/s41598-018-30786-y)
Sci.Rep., 9 (1)
Author count: 11
Formicola B., Dal Magro R., Montefusco-Pereira C.V., Lehr C.M., Koch M., Russo L., Grasso G., Deriu M.A., Danani A., ... , Bourdoulous S., Re F.
(2019)
The synergistic effect of chlorotoxin-mApoE in boosting drug-loaded liposomes across the BBB
J.Nanobiotechnology., 17 (1)
Author count: 9
Christmann R., Thomas C., Jager N., Raber A.S., Loretz B., Schaefer U.F., Tschernig T., ... , Vogt T., Lehr C.M.
(2020)
Nanoparticle Targeting to Scalp Hair Follicles: New Perspectives for a Topical Therapy for Alopecia Areata
J.Invest.Dermatol., 140 (1)
Author count: 10
Artzy-Schnirman A., Zidan H., Elias-Kirma S., Ben-Porat L., Tenenbaum-Katan J., Carius P., Fishler R., Schneider-Daum N., ... , Lehr C.M., Sznitman J.
(2019)
Capturing the Onset of Bacterial Pulmonary Infection in Acini-On-Chips
Adv.Biosyst., 3 (9)
Author count: 6
Ho D.K., Nichols B.L.B., Edgar K.J., Murgia X., Loretz B., Lehr C.M.
(2019)
Challenges and Strategies in Drug Delivery Systems for Treatment of Pulmonary Infections
Eur.J.Pharm.Biopharm., 144 (November)
Author count: 6
Artzy-Schnirman A., Hobi N., Schneider-Daum N., Guenat O.T., Lehr C.M., Sznitman J.
(2019)
Advanced in vitro lung-on-chip platforms for inhalation assays: From prospect to pipeline
Eur.J.Pharm.Biopharm., 144 (November)
Author count: 8
Salomon J.J., Gausterer J.C., Selo M.A., Hosoya K.I., Huwer H., Schneider-Daum N., ... , Lehr C.M., Ehrhardt C.
(2019)
OCTN2-mediated acetyl-l-carnitine transport in human pulmonary epithelial cells in vitro
Pharmaceutics, 11 (8)
Author count: 15
Thanki K., van Eetvelde D., Geyer A., Fraire J., Hendrix R., Van Eygen H., Putteman E., Sami H., De Souza Carvalho-Wodarz C., Franzyk H., Nielsen H.M., Braeckmans K., Lehr C.M., ... , Ogris M., Foged C.
(2019)
Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration
J.Control.Release, 310
Author count: 9
de Andrade D.F., Vukosavljevic B., Hoppe J.B., Pohlmann A.R., Guterres S.S., Windbergs M., Külkamp-Guerreiro I., ... , Salbego C.G., Beck R.C.R.
(2019)
Redispersible Spray-Dried Powder Containing Nanoencapsulated Curcumin: the Drying Process Does Not Affect Neuroprotection In vitro
AAPS PharmSciTech, 20 (7)
Author count: 7
Durán V., Yasar H., Becker J., Thiyagarajan D., Loretz B., ... , Kalinke U., Lehr C.M.
(2019)
Preferential uptake of chitosan-coated PLGA nanoparticles by primary human antigen presenting cells
Nanomed.Nanotechnol.Biol.Med., 21
Author count: 8
Menina S., Eisenbeis J., Kamal M.A.M., Koch M., Bischoff M., Gordon S., ... , Loretz B., Lehr C.M.
(2019)
Bioinspired Liposomes for Oral Delivery of Colistin to Combat Intracellular Infections by Salmonella enterica
Adv.Healthc.Mater., 8 (17)
Author count: 1
Lehr C.-M.
(2019)
Arzneimittel gegen Magengeschwüre : Humboldt-Preisträgerin erforscht in Saarbrücken das Potenzial einer tropischen Baumrinde
Dtsch.Apoth.Ztg., 159 (11)
Author count: 8
Kletting S., Barthold S., Repnik U., Griffiths G., Loretz B., Schneider-Daum N., ... , De Souza Carvalho-Wodarz C., Lehr C.M.
(2018)
Co-culture of human alveolar epithelial (hAELVi) and macrophage (THP-1) cell lines
ALTEX, 35 (2)
Author count: 15
Graef F., Richter R., Fetz V., Murgia X., De Rossi C., Schneider-Daum N., Allegretta G., Elgaher W., Haupenthal J., Empting M., Beckmann F., Brönstrup M., Hartmann R., ... , Gordon S., Lehr C.M.
(2018)
In Vitro Model of the Gram-Negative Bacterial Cell Envelope for Investigation of Anti-Infective Permeation Kinetics
ACS Infect.Dis., 4 (8)
Author count: 5
Costa A., De Souza Carvalho-Wodarz C., Seabra V., Sarmento B., Lehr C.M.
(2019)
Triple co-culture of human alveolar epithelium, endothelium and macrophages for studying the interaction of nanocarriers with the air-blood barrier
Acta Biomater., 91
Author count: 15
Salaets T., Gie A., Jimenez J., Aertgeerts M., Gheysens O., Velde G.V., Koole M., Murgia X., Casiraghi C., Ricci F., Salomone F., Villetti G., Allegaert K., ... , Deprest J., Toelen J.
(2019)
Local pulmonary drug delivery in the preterm rabbit: Feasibility and efficacy of daily intratracheal injections
Am.J.Physiol.Lung Cell.Mol.Physiol., 316 (4)
Author count: 9
Nnamani P., Ugwu A., Ibezim E., Onoja S., Odo A., Windbergs M., Rossi C., ... , Lehr C.M., Attama A.
(2019)
Preparation, characterization and in vitro antibacterial property of Ciprofloxacin-loaded nanostructured lipid carrier for treatment of Bacillus subtilis infection
J.Microencapsul., 36 (1)
Author count: 9
Castoldi A., Empting M., De Rossi C., Mayr K., Dersch P., Hartmann R., Müller R., ... , Gordon S., Lehr C.M.
(2019)
Aspherical and Spherical InvA497-Functionalized Nanocarriers for Intracellular Delivery of Anti-Infective Agents
Pharm.Res., 36 (1)
Author count: 2
Wang J., Windbergs M.
(2019)
Controlled dual drug release by coaxial electrospun fibers - Impact of the core fluid on drug encapsulation and release
Int.J.Pharm., 556
Author count: 12
Vukosavljevic B., Hittinger M., Hachmeister H., Pilger C., Murgia X., Gepp M.M., Gentile L., Huwer H., Schneider-Daum N., Huser T., ... , Lehr C.M., Windbergs M.
(2019)
Vibrational spectroscopic imaging and live cell video microscopy for studying differentiation of primary human alveolar epithelial cells
J.Biophotonics., 12 (6)
Author count: 19
Haque A.K.M.A., Dewerth A., Antony J.S., Riethmüller J., Schweizer G.R., Weinmann P., Latifi N., Yasar H., Pedemonte N., Sondo E., Weidensee B., Ralhan A., Laval J., Schlegel P., Seitz C., Loretz B., Lehr C.M., ... , Handgretinger R., Kormann M.S.D.
(2018)
Chemically modified hCFTR mRNAs recuperate lung function in a mouse model of cystic fibrosis
Sci.Rep., 8 (1)
Author count: 1
Hansen S.
(2017)
Near-infrared densitometry for improved standardization of tape stripping and in situ determination of the total stratum corneum thickness
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Author count: 5
Hering S., Loretz B., Friedli T., Lehr C.M., Stieneker F.
(2018)
Can lifecycle management safeguard innovation in the pharmaceutical industry?
Drug Discov.Today
Author count: 6
Ruge C.A., Driessen M.D., Haase A., Schäfer U.F., Luch A., Lehr C.-M.
(2014)
Analyzing the Biological Entitiy of Nanomaterials : Characterization of Nanomaterial Properties in Biological Matrices
, 1 (4)
Author count: 4
Malaeksefat E., Barthold S., Loretz B., Lehr C.M.
(2014)
Lessons learned from pharmaceutical nanomaterials
, 1 (6)
Author count: 4
Wohlleben W., Kuhlbusch T.A.J., Schnekenburger J., Lehr C.M.
(2014)
Perspectives
, 1.
Author count: 11
Stucki J.D., Hobi N., Galimov A., Stucki A.O., Schneider-Daum N., Lehr C.M., Huwer H., Frick M., Funke-Chambour M., ... , Geiser T., Guenat O.T.
(2018)
Medium throughput breathing human primary cell alveolus-on-chip model
Sci.Rep., 8 (1)
Author count: 7
Yasar H., Biehl A., de Rossi C., Koch M., Murgia X., ... , Loretz B., Lehr C.M.
(2018)
Kinetics of mRNA delivery and protein translation in dendritic cells using lipid-coated PLGA nanoparticles
J.Nanobiotechnology., 16 (1)
Author count: 4
Floroiu A., Klein M., Krämer J., Lehr C.M.
(2018)
Towards standardized dissolution techniques for in vitro performance testing of dry powder inhalers
Diss.Tech, 25 (3)
Author count: 10
Pontes M.S., Montefusco-Pereira C.V., Misra B.B., Ribeiro-Junior H.L., Graciano D.E., Santos J.S., Nobrega M.A.S., Fernandes S.S.L., ... , Caires A.R.L., Santiago E.F.
(2018)
High-throughput phenotyping by applying digital morphometrics and fluorescence induction curves in seeds to identifying variations: A case study of Annona (Annonaceae) species
Information Processing in Agriculture
Author count: 2
Wang J., Windbergs M.
(2018)
Influence of polymer composition and drug loading procedure on dual drug release from PLGA:PEG electrospun fibers
Eur.J.Pharm.Sci., 124
Author count: 6
Frank J., Richter M., De Rossi C., Lehr C.M., Fuhrmann K., Fuhrmann G.
(2018)
Extracellular vesicles protect glucuronidase model enzymes during freeze-drying
Sci.Rep., 8 (1)
Author count: 13
Ricci F., Casiraghi C., Storti M., D'Alò F., Catozzi C., Ciccimarra R., Ravanetti F., Cacchioli A., Villetti G., Civelli M., Murgia X., ... , Carnielli V., Salomone F.
(2018)
Surfactant replacement therapy in combination with different non-invasive ventilation techniques in spontaneously-breathing, surfactant-depleted adult rabbits
PLoS ONE, 13 (7)
Author count: 5
Savla R., Hartwig O., Lim Chin W.W., Loretz B., Lehr C.M.
(2018)
Oral delivery of macromolecular drugs
Pharm.Technol.Eur., 42 (7)
Author count: 11
Müller L., Murgia X., Siebenbürger L., Börger C., Schwarzkopf K., Sewald K., Häußler S., Braun A., Lehr C.M., ... , Hittinger M., Wronski S.
(2018)
Human airway mucus alters susceptibility of Pseudomonas aeruginosa biofilms to tobramycin, but not colistin
J.Antimicrob.Chemother., 73 (10)
Author count: 10
Ho D.K., Frisch S., Biehl A., Terriac E., de Rossi C., Schwarzkopf K., Lautenschlager F., Loretz B., ... , Murgia X., Lehr C.M.
(2018)
Farnesylated Glycol Chitosan as a Platform for Drug Delivery: Synthesis, Characterization, and Investigation of Mucus-Particle Interactions
Biomacromolecules., 19 (8)
Author count: 8
Ramsis T.M., Abdel Karim S.E., Vassilaki N., Frakolaki E., Kamal A.A.M., Zoidis G., ... , Ahmed N.S., Abadi A.H.
(2018)
Expanding the chemical space of anti-HCV NS5A inhibitors by stereochemical exchange and peptidomimetic approaches
Arch.Pharm., 351 (7)
Author count: 4
Wang J., Planz V., Vukosavljevic B., Windbergs M.
(2018)
Multifunctional electrospun nanofibers for wound application - Novel insights into the control of drug release and antimicrobial activity
Eur.J.Pharm.Biopharm., 129 (Aug)
Author count: 10
Sapich S., Hittinger M., Hendrix-Jastrzebski R., Repnik U., Griffiths G., May T., Wirth D., Bals R., ... , Schneider-Daum N., Lehr C.M.
(2018)
Murine alveolar epithelial cells and their lentivirus-mediated immortalisation
Altern.Lab Anim, 46 (2)
Author count: 7
Metz J., Knoth K., Gross H., Lehr C.M., Stäbler C., ... , Bock U., Hittinger M.
(2018)
Combining MucilAir and Vitrocell((R)) Powder Chamber for the In Vitro Evaluation of Nasal Ointments in the Context of Aerosolized Pollen
Pharmaceutics., 10 (2)
Author count: 7
Yasar H., Ho D.K., De Rossi C., Herrmann J., Gordon S., ... , Loretz B., Lehr C.M.
(2018)
Starch-chitosan polyplexes: A versatile carrier system for anti-infectives and gene delivery
Polym., 10 (3)
Author count: 6
Ho D.K., Costa A., De Rossi C., De Souza Carvalho-Wodarz C., Loretz B., Lehr C.M.
(2018)
Polysaccharide Submicrocarrier for Improved Pulmonary Delivery of Poorly Soluble Anti-infective Ciprofloxacin: Preparation, Characterization, and Influence of Size on Cellular Uptake
Mol.Pharm., 15 (3)
Author count: 11
Ricci F., Salomone F., Kuypers E., Ophelders D., Nikiforou M., Willems M., Krieger T., Murgia X., Hütten M., ... , Kramer B.W., Bianco F.
(2017)
In vivo evaluation of the acute pulmonary response to poractant alfa and Bovactant treatments in lung-lavaged adult rabbits and in preterm lambs with respiratory distress syndrome
Front.Pediatr., 5
Author count: 10
Vogt T., Thomas C., Reichrath J., Schilling L., Mawlood D., Christmann R., Loretz B., Schäfer U., ... , Lehr C.M., Müller C.
(2018)
Postmenopausaler Lichen planopilaris alias fibrosierende frontotemporale Alopezie Kossard : Ein evidenzorientierter „practical guide to treatment" des Haarforschungszentrums der Dr. Rolf M. Schwiete Stiftung an der Universität des Saarlandes. [Postmenopausal lichen planopilaris also known as fibrosing frontotemporal alopecia Kossard: An evidence-oriented practical guide to treatment from the University of the Saarland, Hair Research Center of the Dr. Rolf M. Schwiete Foundation]
Hautarzt, 69 (2)
Author count: 27
Serr I., Scherm M.G., Zahm A.M., Schug J., Flynn V.K., Hippich M., Kälin S., Becker M., Achenbach P., Nikolaev A., Gerlach K., Liebsch N., Loretz B., Lehr C.M., Kirchner B., Spornraft M., Haase B., Segars J., Küper C., Palmisano R., Waisman A., Willis R.A., Kim W.U., Weigmann B., Kaestner K.H., ... , Ziegler A.G., Daniel C.
(2018)
A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes
Sci.Transl.Med., 10 (422)
Author count: 4
Selzer D., Schaefer U.F., Lehr C.M., Hansen S.
(2017)
Basic mathematics in skin absorption
(1)
Author count: 4
Schaefer U.F., Selzer D., Hansen S., Lehr C.M.
(2017)
Human native and reconstructed skin preparations for in vitro penetration and permeation studies
(10)
Author count: 16
Ricci F., Catozzi C., Ravanetti F., Murgia X., Macchidani N., Sgarbi E., Di Lallo V., Saccani F., Pertile M., Cacchioli A., Catinella S., Villetti G., Civelli M., Amadei F., ... , Stellari F.F., Pioselli B.
(2017)
In vitro and in vivo characterization of poractant alfa supplemented with budesonide for safe and effective intratracheal administration
Pediatr.Res., 82 (6)
Author count: 5
Murgia X., Loretz B., Hartwig O., Hittinger M., Lehr C.M.
(2017)
The role of mucus on drug transport and its potential to affect therapeutic outcomes
Adv.Drug Deliv.Rev., 124
Author count: 7
Andrade D.F., Vukosavljevic B., Benvenutti E.V., Pohlmann A.R., Guterres S.S., ... , Windbergs M., Beck R.C.R.
(2017)
Redispersible spray-dried lipid-core nanocapsules intended for oral delivery: the influence of the particle number on redispersibility
Pharm.Dev.Technol., 23 (4)
Author count: 3
Seif S., Planz V., Windbergs M.
(2017)
Delivery of Therapeutic Proteins Using Electrospun Fibers-Recent Developments and Current Challenges
Arch.Pharm., 350 (10)
Author count: 3
Planz V., Wang J., Windbergs M.
(2017)
Establishment of a cell-based wound healing assay for bio-relevant testing of wound therapeutics
J.Pharmacol.Toxicol.Methods, 89
Author count: 6
Ribeiro G.M., Matsumoto C.K., Real F., Teixeira D., Duarte R.S., Mortara R.A.
(2017)
Increased survival and proliferation of the epidemic strain Mycobacterium abscessus subsp. massiliense CRM0019 in alveolar epithelial cells
BMC Microbiol., 17 (1)
Author count: 6
Hittinger M., Janke J., Huwer H., Scherließ R., Schneider-Daum N., Lehr C.M.
(2016)
Autologous co-culture of primary human alveolar macrophages and epithelial cells for investigating aerosol medicines. Part I: Model Characterisation
ATLA Altern.Lab.Anim., 44 (4)
Author count: 6
Yasar H., Gordon S., Loretz B., Schulze K., Guzmán C.A., Lehr C.-M.
(2016)
Follicular Drug Delivery: a Root to Success - delivering drugs through the skin without the use of needles has proven a significant challenge for the scientific community. But what about exploiting hair follicles?
The Medicine Maker (0816-601)
Author count: 9
Sobot D., Mura S., Rouquette M., Vukosavljevic B., Cayre F., Buchy E., Pieters G., ... , Garcia-Argote S., Windbergs M.
(2017)
Circulating Lipoproteins: A Trojan Horse Guiding Squalenoylated Drugs to LDL-Accumulating Cancer Cells
Mol.Ther., 25 (7)
Author count: 3
Hittinger M., Schneider-Daum N., Lehr C.M.
(2017)
Cell and tissue-based in vitro models for improving the development of oral inhalation drug products
Eur.J.Pharm.Biopharm., 118
Author count: 6
Vukosavljevic B., Murgia X., Schwarzkopf K., Schaefer U.F., Lehr C.M., Windbergs M.
(2017)
Tracing molecular and structural changes upon mucolysis with N-acetyl cysteine in human airway mucus
Int.J.Pharm.
Author count: 11
Melero A., Draheim C., Hansen S., Giner E., Jose Carreras J., Talens-Visconti R., Maria Garrigues T., Esteban Peris J., Carmen Recio M., ... , Giner R., Lehr C.M.
(2017)
Targeted delivery of Cyclosporine A by polymeric nanocarriers improves the therapy of inflammatory bowel disease in a relevant mouse model
Eur.J.Pharm.Biopharm., 119
Author count: 8
Beck R.C.R., Chaves P.S., Goyanez A., Vukosavljevic B., Buanz A., Windbergs M., ... , Basit A.W., Gaisford S.
(2017)
3D printed tablets loaded with polymeric nanocapsules: an innovative approach to produce customized drug delivery systems
Int.J.Pharm., 528 (1-2)
Author count: 7
Rigo L.A., Carvalho-Wodarz C.S., Pohlmann A.R., Guterres S.S., Schneider-Daum N., ... , Lehr C.M., Beck R.C.R.
(2017)
Nanoencapsulation of a glucocorticoid improves barrier function and anti-inflammatory effect on monolayers of pulmonary epithelial cell lines
Eur.J.Pharm.Biopharm., 119
Author count: 8
Günday Türeli N., Torge A., Juntke J., Schwarz B.C., Schneider-Daum N., Türeli A.E., ... , Lehr C.M., Schneider M.
(2017)
Ciprofloxacin-loaded PLGA nanoparticles against cystic fibrosis P. aeruginosa lung infections
Eur.J.Pharm.Biopharm., 117
Author count: 8
Nickel S., Selo M.A., Fallack J., Clerkin C.G., Huwer H., Schneider-Daum N., ... , Lehr C.M., Ehrhardt C.
(2017)
Expression and Activity of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Distal Lung Epithelial Cells In Vitro
Pharm.Res., 34 (12)
Author count: 10
Mathes C., Brandner J.M., Laue M., Raesch S.S., Hansen S., Failla A.V., Vidal S., Moll I., ... , Schaefer U.F., Lehr C.M.
(2016)
Tight junctions form a barrier in porcine hair follicles
Eur.J.Cell Biol., 95 (2)
Author count: 5
Vukosavljevic B., De Kinder L., Siepmann J., Muschert S., Windbergs M.
(2016)
Novel insights into controlled drug release from coated pellets by confocal Raman microscopy
J.Raman Spectrosc., 47 (7)
Author count: 4
Goikoetxea E., Rivas A., Murgia X., Antón R.
(2017)
Mathematical modeling and numerical simulation of surfactant delivery within a physical model of the neonatal trachea for different aerosol characteristics
Aerosol Sci.Technol., 51 (2)
Author count: 3
Seif S., Planz V., Windbergs M.
(2017)
Controlling the Release of Proteins from Therapeutic Nanofibers: The Effect of Fabrication Modalities on Biocompatibility and Antimicrobial Activity of Lysozyme
Planta Med., 83 (5)
Author count: 6
Loretz B., Schneider-Daum N., Windbergs M., Schafer U., Schneider M., Lehr C.M.
(2017)
Barriers and motivations for non-invasive drug delivery
Eur.J.Pharm.Biopharm., 118 (September)
Author count: 8
Loretz B., Jain R., Dandekar P., Thiele C., Hiroe Y., Mostaghaci B., ... , Qiong L., Lehr C.M.
(2016)
Nanomaterials for pharmaceutical applications
, 1 (12)
Author count: 8
Murgia X., Yasar H., Carvalho-Wodarz C., Loretz B., Gordon S., Schwarzkopf K., ... , Schaefer U., Lehr C.M.
(2017)
Modelling the bronchial barrier in pulmonary drug delivery: A human bronchial epithelial cell line supplemented with human tracheal mucus
Eur.J.Pharm.Biopharm., 118 (Sep)
Author count: 2
Labouta H.I., Schneider M.
(2016)
Nanotechnology and the skin barrier: Topical and transdermal nanocarrier-based delivery
, 1 (30)
Author count: 86
Pelaz B., Alexiou C., varez-Puebla R.A., Alves F., Andrews A.M., Ashraf S., Balogh L.P., Ballerini L., Bestetti A., Brendel C., Bosi S., Carril M., Chan W.C.W., Chen C., Chen X., Chen X., Cheng Z., Cui D., Du J., Dullin C., Escudero A., Feliu N., Gao M., George M., Gogotsi Y., Grünweller A., Gu Z., Halas N.J., Hampp N., Hartmann R.K., Hersam M.C., Hunziker P., Jian J., Jiang X., Jungebluth P., Kadhiresan P., Kataoka K., Khademhosseini A., Kopecek J., Kotov N.A., Krug H.F., Lee D.S., Lehr C.M., Leong K.W., Liang X.J., Ling Lim M., Liz-Marzan L.M., Ma X., Macchiarini P., Meng H., Möhwald H., Mulvaney P., Nel A.E., Nie S., Nordlander P., Okano T., Oliveira J., Park T.H., Penner R.M., Prato M., Puntes V., Rotello V.M., Samarakoon A., Schaak R.E., Shen Y., Sjöqvist S., Skirtach A.G., Soliman M.G., Stevens M.M., Sung H.W., Tang B.Z., Tietze R., Udugama B.N., VanEpps J.S., Weil T., Weiss P.S., Willner I., Wu Y., Yang L., Yue Z., Zhang Q., Zhang Q., Zhang X.E., Zhao Y., ... , Zhou X., Parak W.J.
(2017)
Diverse Applications of Nanomedicine
ACS Nano, 11 (3)
Author count: 6
Gross A., Torge A., Schaefer U.F., Schneider M., Lehr C.M., Wagner C.
(2017)
A foam model highlights the differences of the macro- and microrheology of respiratory horse mucus
J Mech.Behav.Biomed.Mater., 71 (Jul)
Author count: 5
Ricci F., Murgia X., Razzetti R., Pelizzi N., Salomone F.
(2017)
In vitro and in vivo comparison between poractant alfa and the new generation synthetic surfactant CHF5633
Pediatr.Res., 81 (2)
Author count: 4
Seif S., Graef F., Gordon S., Windbergs M.
(2016)
Monitoring drug release from electrospun fibers using an in situ fiber-optic system
Diss.Tech, 23 (2)
Author count: 4
Aguillera Forte A.L.S., Melero A., Ruver Beck R.C., Lehr C.M.
(2016)
Polyester particles for drug delivery to the skin: Local and systemic applications
(11)
Author count: 14
Ricci F., Catozzi C., Murgia X., Rosa B., Amidani D., Lorenzini L., Bianco F., Rivetti C., Catinella S., Villetti G., Civelli M., Pioselli B., ... , Dani C., Salomone F.
(2017)
Physiological, biochemical, and biophysical characterization of the lung-lavaged spontaneously-breathing rabbit as a model for respiratory distress syndrome
PLoS ONE, 12 (1)
Author count: 6
Ernst M., John T., Guenther M., Wagner C., Schaefer U.F., Lehr C.M.
(2017)
A Model for the Transient Subdiffusive Behavior of Particles in Mucus
Biophys.J., 112 (1)
Author count: 11
Nnamani P.O., Ugwu A.A., Ibezim E.C., Kenechukwu F.C., Akpa P.A., Ogbonna J.D.N., Obitte N.C., Odo A.N., Windbergs M., ... , Lehr C.M., Attama A.A.
(2016)
Sustained-release liquisolid compact tablets containing artemether-lumefantrine as alternate-day regimen for malaria treatment to improve patient compliance
Int.J.Nanomed., 11
Author count: 9
Castoldi A., Herr C., Niederstrasser J., Ibrahim Labouta H., Melero A., Gordon S., Schneider-Daum N., ... , Bals R., Lehr C.M.
(2016)
Calcifediol-loaded liposomes for local treatment of pulmonary bacterial infections
Eur.J Pharm.Biopharm, 118 (Sep)
Author count: 6
Niederstrasser J., Herr C., Wolf L., Lehr C.M., Beisswenger C., Bals R.
(2016)
Vitamin D deficiency does not result in a breach of host defense in murine models of pneumonia
Infect.Immun., 84 (11)
Author count: 18
Serr I., Fürst R.W., Ott V.B., Scherm M.G., Nikolaev A., Gökmen F., Zillmer S., Bunk M., Weigmann B., Kunschke N., Loretz B., Lehr C.M., Kirchner B., Haase B., Pfaffl M., Waisman A., ... , Willis R.A., Ziegler A.G.
(2016)
MiRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity
Proc.Natl.Acad.Sci.U.S.A., 113 (43)
Author count: 11
Graef F., Vukosavljevic B., Michel J.P., Wirth M., Ries O., de Rossi C., Windbergs M., Rosilio V., Ducho C., ... , Gordon S., Lehr C.M.
(2016)
The bacterial cell envelope as delimiter of anti-infective bioavailability - An in vitro permeation model of the Gram-negative bacterial inner membrane
J Control Release, 243
Author count: 6
Hittinger M., Mell N.A., Huwer H., Loretz B., Schneider-Daum N., Lehr C.M.
(2016)
Autologous co-culture of primary human alveolar macrophages and epithelial cells for investigating aerosol medicines. Part II: Evaluation of IL-10-loaded microparticles for the treatment of lung inflammation
ATLA Altern.Lab.Anim., 44 (4)
Author count: 3
Thiele C., Loretz B., Lehr C.M.
(2016)
Biodegradable starch derivatives with tunable charge density-synthesis, characterization, and transfection efficiency
Drug Deliv.Transl.Res, 7 (2)
Author count: 5
Kanber E., Yamada H., Loretz B., Lepeltier E., Lehr C.M.
(2016)
Design of Polyamine-Grafted Starches for Nucleotide Analogue Delivery: In Vitro Evaluation of the Anticancer Activity
Bioconjug.Chem., 27 (10)
Author count: 12
Wolf L., Sapich S., Honecker A., Jungnickel C., Seiler F., Bischoff M., Wonnenberg B., Herr C., Schneider-Daum N., Lehr C.M., ... , Bals R., Beisswenger C.
(2016)
IL-17A-mediated expression of epithelial IL-17C promotes inflammation during acute Pseudomonas aeruginosa pneumonia
Am J Physiol Lung Cell Mol.Physiol, 311 (5)
Author count: 8
Schweinlin M., Wilhelm S., Schwedhelm I., Hansmann J., Rietscher R., Jurowich C., ... , Walles H., Metzger M.
(2016)
Development of an advanced primary human in vitro model of the small intestine
Tissue Eng.Part.C Methods, 22 (9)
Author count: 3
Planz V., Lehr C.M., Windbergs M.
(2016)
In vitro models for evaluating safety and efficacy of novel technologies for skin drug delivery
J Control Release, 242
Author count: 3
Collnot E.M., Susewind J., Lehr C.M.
(2014)
Advanced in vitro models of the intestinal mucosa for drug delivery studies
(8)
Author count: 6
Gaiser B.K., Susewind J., Ucciferri N., Collnot E.M., Ahluwalia A., Stone V.
(2016)
In vitro risk assessment of nanoparticles
(31)
Author count: 9
Kann B., Spengler C., Coradini K., Rigo L.A., Bennink M.L., Jacobs K., Offerhaus H.L., ... , Beck R.C.R., Windbergs M.
(2016)
Intracellular Delivery of Poorly Soluble Polyphenols: Elucidating the Interplay of Self-Assembling Nanocarriers and Human Chondrocytes
Anal.Chem., 88 (14)
Author count: 6
Schulze K., Ebensen T., Riese P., Prochnow B., Lehr C.M., Guzmán C.A.
(2016)
New Horizons in the Development of Novel Needle-Free Immunization Strategies to Increase Vaccination Efficacy
Curr Top.Microbiol.Immunol., 398
Author count: 7
Buchy E., Vukosavljevic B., Windbergs M., Sobot D., Dejean C., ... , Mura S., Couvreur P.
(2016)
Synthesis of a deuterated probe for the confocal Raman microscopy imaging of squalenoyl nanomedicines
Beilstein J.Org.Chem., 12
Author count: 5
Lauth V., Loretz B., Lehr C.M., Maas M., Rezwan K.
(2016)
Self-Assembly and Shape Control of Hybrid Nanocarriers Based on Calcium Carbonate and Carbon Nanodots
Chem.Mater., 28 (11)
Author count: 11
Brito Baleeiro R., Schweinlin M., Rietscher R., Diedrich A., Czaplewska J.A., Metzger M., Michael Lehr C., Scherließ R., Hanefeld A., ... , Gottschaldt M., Walden P.
(2016)
Nanoparticle-based mucosal vaccines targeting tumor-associated antigens to human dendritic cells
J.Biomed.Nanotechnol., 12 (7)
Author count: 6
Bokkasam H., Ernst M., Guenther M., Wagner C., Schaefer U.F., Lehr C.M.
(2016)
Different macro- and micro-rheological properties of native porcine respiratory and intestinal mucus
Int.J Pharm., 510
Author count: 7
Planz V., Seif S., Atchison J.S., Vukosavljevic B., Sparenberg L., ... , Kroner E., Windbergs M.
(2016)
Three-dimensional hierarchical cultivation of human skin cells on bio-adaptive hybrid fibers
Integr.Biol.(Camb.), 8
Author count: 7
Menina S., Labouta H.I., Geyer R., Krause T., Gordon S., ... , Dersch P., Lehr C.M.
(2016)
Invasin-functionalized liposome nanocarriers improve the intracellular delivery of anti-infective drugs
RSC Adv., 6 (47)
Author count: 7
Teubl B.J., Leitinger G., Schneider M., Lehr C.M., Fröhlich E., ... , Zimmer A., Roblegg E.
(2015)
The buccal mucosa as a route for TiO2 nanoparticle uptake
Nanotoxicology, 9 (2)
Author count: 6
Murgia X., Pawelzyk P., Schaefer U.F., Wagner C., Willenbacher N., Lehr C.M.
(2016)
Size-Limited Penetration of Nanoparticles into Porcine Respiratory Mucus after Aerosol Deposition
Biomacromolecules, 17 (4)
Author count: 7
Barthold S., Kletting S., Taffner J., De Souza Carvalho-Wodarz C., Lepeltier E., ... , Loretz B., Lehr C.M.
(2016)
Preparation of nanosized coacervates of positive and negative starch derivatives intended for pulmonary delivery of proteins
J.Mater.Chem.B, 4 (13)
Author count: 5
Le Guevel X., Spies C., Daum N., Jung G., Schneider M.
(2012)
Highly fluorescent silver nanoclusters stabilized by glutathione: a promising fluorescent label for bioimaging
Nano Research, 5 (6)
Author count: 7
Teubl B., Leitinger G., Frohlich E., Schneider M., Lehr C.-M., ... , Zimmer A., Roblegg E.
(2014)
Investigations of the oral uptake of titanium dioxide nanoparticles via the buccal mucosa
Nanoscale Science and Engineering Forum 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future
Author count: 7
Schulze K., Mittal A., Hansen S., Ebensen T., Weißmann S., ... , Guzmán C.A., Lehr C.-M.
(2015)
Impfung durch Eincremen: Transkutane Immunisierung mittels Nanopartikel
GIT - Laborfachzeitschrift, 4
Author count: 7
Schrank S., Kann B., Windbergs M., Glasser B., Zimmer A., ... , Khinast J., Roblegg E.
(2014)
Ibuprofen-loaded calcium stearate matrix-pellets: Impact of the drying temperature on the final pellet characteristics
Particle Technology Forum 2014 - Core Programming Area at the 2014 AIChE Annual Meeting
Author count: 5
Neumeyer A., Bukowski M., Veith M., Lehr C.M., Daum N.
(2014)
Non-invasive determination of cellular oxygen consumption as novel cytotoxicity assay for nanomaterials
Nanotoxicology, 8 (1)
Author count: 9
Raber A.S., Mittal A., Schäfer J., Bakowsky U., Reichrath J., Vogt T., Schaefer U.F., ... , Hansen S., Lehr C.M.
(2014)
Quantification of nanoparticle uptake into hair follicles in pig ear and human forearm
J.Control.Release, 179 (1)
Author count: 8
Ucciferri N., Collnot E.M., Gaiser B.K., Tirella A., Stone V., Domenici C., ... , Lehr C.M., Ahluwalia A.
(2014)
In vitro toxicological screening of nanoparticles on primary human endothelial cells and the role of flow in modulating cell response
Nanotoxicology, 8 (6)
Author count: 3
Mostaghaci B., Loretz B., Lehr C.M.
(2016)
Calcium phosphate system for gene delivery: Historical background and emerging opportunities
Curr.Pharm.Des., 22 (11)
Author count: 18
Wohlleben W., Driessen M.D., Raesch S., Schaefer U.F., Schulze C., Vacano B.V., Vennemann A., Wiemann M., Ruge C.A., Platsch H., Mues S., Ossig R., Tomm J.M., Schnekenburger J., Kuhlbusch T.A., Luch A., ... , Lehr C.M., Haase A.
(2016)
Influence of agglomeration and specific lung lining lipid/protein interaction on short-term inhalation toxicity
Nanotoxicology., 10 (7)
Author count: 12
Kuehn A., Kletting S., de Souza Carvalho-Wodarz, Repnik U., Griffiths G., Fischer U., Meese E., Huwer H., Wirth D., May T., ... , Schneider-Daum N., Lehr C.M.
(2016)
Human alveolar epithelial cells expressing tight junctions to model the air-blood barrier
ALTEX., 33
Author count: 1
Windbergs M.
(2016)
On-chip fabrication of drug delivery systems
(6)
Author count: 3
Graef F., Gordon S., Lehr C.M.
(2016)
Anti-infectives in Drug Delivery-Overcoming the Gram-Negative Bacterial Cell Envelope
Curr Top.Microbiol.Immunol., 398
Author count: 7
Susewind J., De Souza Carvalho-Wodarz C., Repnik U., Collnot E.M., Schneider-Daum N., ... , Griffiths G.W., Lehr C.M.
(2016)
A 3D co-culture of three human cell lines to model the inflamed intestinal mucosa for safety testing of nanomaterials
Nanotoxicology, 10 (1)
Author count: 11
Rietscher R., Schr÷der M., Janke J., Czaplewska J., Gottschaldt M., Scherließ R., Hanefeld A., Schubert U.S., Schneider M., ... , Knolle P.A., Lehr C.M.
(2016)
Antigen delivery via hydrophilic PEG-b-PAGE-b-PLGA nanoparticles boosts vaccination induced T cell immunity
Eur.J.Pharm.Biopharm., 102
Author count: 6
Sterner B., Harms M., W÷ll S., Weigandt M., Windbergs M., Lehr C.M.
(2016)
The effect of polymer size and charge of molecules on permeation through synovial membrane and accumulation in hyaline articular cartilage
Eur.J.Pharm.Biopharm., 101
Author count: 6
Puncochova K., Vukosavljevic B., Hanus J., Beranek J., Windbergs M., Stepanek F.
(2016)
Non-invasive insight into the release mechanisms of a poorly soluble drug from amorphous solid dispersions by confocal Raman microscopy
Eur.J.Pharm.Biopharm., 101
Author count: 2
Popp J., Windbergs M.
(2015)
Preface: Pharmaceutical applications of Raman spectroscopy - From diagnosis to therapeutics
Adv.Drug Deliv.Rev., 89
Author count: 7
Dandekar P., Jain R., Keil M., Loretz B., Koch M., ... , Wenz G., Lehr C.M.
(2015)
Enhanced uptake and siRNA-mediated knockdown of a biologically relevant gene using cyclodextrin polyrotaxane
Journal of Materials Chemistry B, 3 (13)
Author count: 7
Rietscher R., Czaplewska J.A., Majdanski T.C., Gottschaldt M., Schubert U.S., ... , Schneider M., Lehr C.M.
(2016)
Impact of PEG and PEG-b-PAGE modified PLGA on nanoparticle formation, protein loading and release
Int.J Pharm., 500
Author count: 7
Kenngott E.E., Kiefer R., Schneider-Daum N., Hamann A., Schneider M., ... , Schmitt M.J., Breinig F.
(2016)
Surface-modified yeast cells: A novel eukaryotic carrier for oral application
J.Control.Release, 224
Author count: 15
Mathes C., Melero A., Conrad P., Vogt T., Rigo L., Selzer D., Prado W.A., de Rossi C., Garrigues T.M., Hansen S., Guterres S.S., Pohlmann A.R., Beck R.C., ... , Lehr C.M., Schaefer U.F.
(2016)
Nanocarriers for optimizing the balance between interfollicular permeation and follicular uptake of topically applied clobetasol to minimize adverse effects
J Control Release, 223
Author count: 6
Ali H., Weigmann B., Collnot E.M., Khan S.A., Windbergs M., Lehr C.M.
(2015)
Budesonide Loaded PLGA Nanoparticles for Targeting the Inflamed Intestinal Mucosa-Pharmaceutical Characterization and Fluorescence Imaging
Pharm.Res, 33 (5)
Author count: 9
Raesch S.S., Tenzer S., Storck W., Rurainski A., Selzer D., Ruge C.A., Perez-Gil J., ... , Schaefer U.F., Lehr C.M.
(2015)
Proteomic and Lipidomic Analysis of Nanoparticle Corona upon Contact with Lung Surfactant Reveals Differences in Protein, but Not Lipid Composition
ACS Nano., 9
Author count: 29
Gordon S., Daneshian M., Bouwstra J., Caloni F., Constant S., Davies D.E., Dandekar G., Guzmán C.A., Fabian E., Haltner E., Hartung T., Hasiwa N., Hayden P., Kandarova H., Khare S., Krug H.F., Kneuer C., Leist M., Lian G., Marx U., Metzger M., Ott K., Prieto P., Roberts M.S., Roggen E.L., Tralau T., van den Braak C., ... , Walles H., Lehr C.M.
(2015)
Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology
ALTEX., 32 (4)
Author count: 7
Labouta H.I., Menina S., Kochut A., Gordon S., Geyer R., ... , Dersch P., Lehr C.M.
(2015)
Bacteriomimetic invasin-functionalized nanocarriers for intracellular delivery
J Control Release, 220
Author count: 6
Guillot A., Couffin A.C., Sejean X., Navarro F., Limberger M., Lehr C.M.
(2015)
Solid Phase Extraction as an Innovative Separation Method for Measuring Free and Entrapped Drug in Lipid Nanoparticles
Pharm.Res., 32 (12)
Author count: 5
Tscheka C., Hittinger M., Lehr C.M., Schneider-Daum N., Schneider M.
(2015)
Macrophage uptake of cylindrical microparticles investigated with correlative microscopy
Eur.J.Pharm.Biopharm., 95
Author count: 12
Schwagerus E., Sladek S., Buckley S.T., rmas-Capote N., de la Rosa D.A., Harvey B.J., Fischer H., Illek B., Huwer H., Schneider-Daum N., ... , Lehr C.M., Ehrhardt C.
(2015)
Expression and function of the epithelial sodium channel ?-subunit in human respiratory epithelial cells in vitro
Pflug.Arch.Eur.J.Physiol., 467 (11)
Author count: 6
Sbrana T., Ucciferri N., Ahmed S., Collnot E.M., Lehr C.M., Ahluwalia A.
(2016)
Dual flow bioreactor with ultrathin microporous TEER sensing membrane for evaluation of nanoparticle toxicity
Sens Actuators, B Chem, 223
Author count: 4
Lepeltier E.A., Nuhn L., Lehr C.M., Zentel R.
(2015)
Not just for tumor targeting: unmet medical needs and opportunities for nanomedicine
Nanomedicine (Lond), 10
Author count: 9
Baleeiro R.B., Rietscher R., Diedrich A., Czaplewska J.A., Lehr C.M., Scherließ R., Hanefeld A., ... , Gottschaldt M., Walden P.
(2015)
Spatial separation of the processing and MHC class I loading compartments for cross-presentation of the tumor-associated antigen HER2/neu by human dendritic cells
Oncoimmunology, 4 (11)
Author count: 6
May S., Kind S., Jensen B., Wolkenhauer M., Schneider M., Lehr C.M.
(2015)
Miniature in vitro dissolution testing of powders for inhalation
Diss.Tech, 22 (3)
Author count: 9
Salomon J.J., Gausterer J.C., Yahara T., Hosoya K.I., Huwer H., Hittinger M., Schneider-Daum N., ... , Lehr C.M., Ehrhardt C.
(2015)
Organic cation transporter function in different in vitro models of human lung epithelium
Eur.J Pharm.Sci, 80
Author count: 6
May S., Jensen B., Weiler C., Wolkenhauer M., Schneider M., Lehr C.M.
(2014)
Dissolution testing of powders for inhalation: Influence of particle deposition and modeling of dissolution profiles
Pharmaceutical Research, 31 (11)
Author count: 7
Lepeltier E., Loretz B., Desmaele D., Zapp J., Herrmann J., ... , Couvreur P., Lehr C.M.
(2015)
Squalenoylation of Chitosan: A Platform for Drug Delivery?
Biomacromolecules., 16 (9)
Author count: 6
Schneider M., Loretz B., Windbergs M., Schneider-Daum N., Schaefer U.F., Lehr C.M.
(2015)
Biological barriers - Advanced drug delivery, in vitro modelling, and their implications for infection research
Eur.J Pharm.Biopharm, 95
Author count: 4
Kann B., Offerhaus H.L., Windbergs M., Otto C.
(2015)
Raman microscopy for cellular investigations - From single cell imaging to drug carrier uptake visualization
Adv.Drug Deliv.Rev., 89
Author count: 2
Franzen L., Windbergs M.
(2015)
Applications of Raman spectroscopy in skin research - From skin physiology and diagnosis up to risk assessment and dermal drug delivery
Adv.Drug Deliv.Rev., 89
Author count: 6
Friedrich R.B., Kann B., Coradini K., Offerhaus H.L., Beck R.C.R., Windbergs M.
(2015)
Skin penetration behavior of lipid-core nanocapsules for simultaneous delivery of resveratrol and curcumin
Eur.J.Pharm.Sci., 78
Author count: 4
Schiller S., Hanefeld A., Schneider M., Lehr C.M.
(2015)
Focused Ultrasound as a Scalable and Contact-Free Method to Manufacture Protein-Loaded PLGA Nanoparticles
Pharm.Res., 32 (9)
Author count: 9
Haghi M., Hittinger M., Zeng Q., Oliver B., Traini D., Young P.M., Huwer H., ... , Schneider-Daum N., Lehr C.M.
(2015)
Mono- and Cocultures of Bronchial and Alveolar Epithelial Cells Respond Differently to Proinflammatory Stimuli and Their Modulation by Salbutamol and Budesonide
Mol.Pharm., 12
Author count: 5
Dimer F., de Souza Carvalho-Wodarz, Haupenthal J., Hartmann R., Lehr C.M.
(2015)
Inhalable Clarithromycin Microparticles for Treatment of Respiratory Infections
Pharm.Res, 32
Author count: 4
Barakat A., Krämer J., De Souza Carvalho C., Lehr C.M.
(2015)
In vitro G
Diss.Tech, 22 (2)
Author count: 6
Hittinger M., Juntke J., Kletting S., Schneider-Daum N., de Souza Carvalho Cristiane, Lehr C.M.
(2014)
Preclinical safety and efficacy models for pulmonary drug delivery of antimicrobials with focus on in vitro models
Advanced Drug Delivery Reviews, 85
Author count: 23
Mahiny A.J., Dewerth A., Mays L.E., Alkhaled M., Mothes B., Malaeksefat E., Loretz B., Rottenberger J., Brosch D.M., Reautschnig P., Surapolchai P., Zeyer F., Schams A., Carevic M., Bakele M., Griese M., Schwab M., Nurnberg B., Beer-Hammer S., Handgretinger R., Hartl D., ... , Lehr C.M., Kormann M.S.
(2015)
In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency
Nat.Biotechnol., 33
Author count: 6
Selzer D., Neumann D., Neumann H., Kostka K.H., Lehr C.M., Schaefer U.F.
(2015)
A strategy for in-silico prediction of skin absorption in man
Eur.J Pharm.Biopharm, 95
Author count: 8
Nielsen L.H., Nagstrup J., Gordon S., Keller S.S., Ïstergaard J., Rades T., ... , Müllertz A., Boisen A.
(2015)
pH-triggered drug release from biodegradable microwells for oral drug delivery
Biomed.Microdevices, 17 (3)
Author count: 5
Jain R., Dandekar P., Loretz B., Koch M., Lehr C.M.
(2015)
Dimethylaminoethyl methacrylate copolymer-siRNA nanoparticles for silencing a therapeutically relevant gene in macrophages
MedChemComm, 6 (4)
Author count: 7
Meyer M.R., Wagmann L., Schneider-Daum N., Loretz B., Carvalho C.S., ... , Lehr C.M., Maurer H.H.
(2015)
P-glycoprotein Interactions of Novel Psychoactive Substances - stimulation of ATP consumption and transport across Caco-2 Monolayers
Biochem.Pharmacol., 94
Author count: 3
Franzen L., Anderski J., Windbergs M.
(2015)
Quantitative detection of caffeine in human skin by confocal Raman spectroscopy - A systematic in vitro validation study
Eur.J Pharm.Biopharm, 95 (Pt A)
Author count: 5
Mostaghaci B., Susewind J., Kickelbick G., Lehr C.M., Loretz B.
(2015)
Transfection system of amino-functionalized calcium phosphate nanoparticles: In vitro efficacy, biodegradability, and immunogenicity study
ACS Appl.Mater.Interfaces, 7 (9)
Author count: 5
Nafee N., Hirosue M., Loretz B., Wenz G., Lehr C.M.
(2015)
Cyclodextrin-based star polymers as a versatile platform for nanochemotherapeutics: Enhanced entrapment and uptake of idarubicin
Colloids Surf.B Biointerfaces, 129
Author count: 7
Mittal A., Schulze K., Ebensen T., Weissmann S., Hansen S., ... , Guzmán C.A., Lehr C.M.
(2015)
Inverse micellar sugar glass (IMSG) nanoparticles for transfollicular vaccination
J.Control.Release, 206
Author count: 5
Melero A., Ferreira Ourique A., Raffin Pohlmann A., Lehr C.M., Ruver Beck R.C.
(2014)
Nanoencapsulation in lipid-core nanocapsules controls mometasone furoate skin permeability rate and its penetration to the deeper skin layers
Skin Pharmacol.Physiol., 27 (4)
Author count: 3
Planz V., Franzen L., Windbergs M.
(2015)
Novel in vitro approaches for the simulation and analysis of human skin wounds
Skin Pharmacol.Physiol., 28 (2)
Author count: 5
Draheim C., de Crecy F., Hansen S., Collnot E.M., Lehr C.M.
(2015)
A Design of Experiment Study of Nanoprecipitation and Nano Spray Drying as Processes to Prepare PLGA Nano- and Microparticles with Defined Sizes and Size Distributions
Pharm.Res, 32 (8)
Author count: 4
Rietscher R., Thum C., Lehr Claus-Michael, Schneider M.
(2014)
Semi-Automated Nanoprecipitation-System-An Option for Operator Independent, Scalable and Size Adjustable Nanoparticle Synthesis
Pharmaceutical Research, 32
Author count: 8
Schrank S., Kann B., Saurugger E., Hainschitz M., Windbergs Maike, Glasser B.J., ... , Khinast J., Roblegg E.
(2015)
The effect of the drying temperature on the properties of wet-extruded calcium stearate pellets: Pellet microstructure, drug distribution, solid state and drug dissolution
International Journal of Pharmaceutics, 478 (2)
Author count: 3
Seif S., Franzen L., Windbergs Maike
(2014)
Overcoming drug crystallization in electrospun fibers - Elucidating key parameters and developing strategies for drug delivery
International Journal of Pharmacology, 478 (1)
Author count: 7
Beber T.C., Andrade D.F., Kann B., Fontana M.C., Coradini K., ... , Windbergs Maike, Beck R.C.R.
(2014)
Submicron polymeric particles prepared by vibrational spray-drying: Semisolid formulation and skin penetration/permeation studies
European Journal of Pharmaceutics and Biopharmaceutics, 88 (3)
Author count: 5
Franzen L., Anderski J., Planz V., Kostka K.H., Windbergs Maike
(2014)
Combining confocal Raman microscopy and freeze-drying for quantification of substance penetration into human skin
Experimental Dermatology, 23 (12)
Author count: 3
De Souza Carvalho C., Daum Nicole, Lehr Claus-Michael
(2014)
Carrier interactions with the biological barriers of the lung: Advanced in vitro models and challenges for pulmonary drug delivery
Advanced Drug Delivery Reviews, 75
Author count: 3
Murgia X., De Souza Carvalho C., Lehr Claus-Michael
(2014)
Overcoming the pulmonary barrier: New insights to improve the efficiency of inhaled therapeutics
European Journal of Nanomedicine, 6 (3)
Author count: 4
Kann B., Teubl B.J., Roblegg E., Windbergs Maike
(2014)
Label-free in vitro visualization of particle uptake into human oral buccal epithelial cells by confocal Raman microscopy
Analyst, 139 (20)
Author count: 11
Goikoetxea E., Murgia Xabier, Serna-Grande P., Soler A., Rey-Santano C., Rivas A., Anton R., Basterretxea F.J., Minambres L., ... , Lopez-Arraiza A., Larrabe-Barrena J.L.
(2014)
In vitro surfactant and perfluorocarbon aerosol deposition in a neonatal physical model of the upper conducting airways
PLoS ONE, 9 (9)
Author count: 4
Nnamani P.O., Hansen Steffi, Windbergs Maike, Lehr Claus-Michael
(2014)
Development of artemether-loaded nanostructured lipid carrier (NLC) formulation for topical application
International Journal of Pharmaceutics, 477
Author count: 7
Mittal A., Schulze K., Ebensen T., Weissmann S., Hansen S., ... , Lehr C.-M., Guzmán C.A.
(2014)
Efficient nanoparticle-mediated needle-free transcutaneous vaccination via hair follicles requires adjuvantation
Nanomedicine, 11 (1)
Author count: 10
Blaudszun A.R., Lian Q., Schnabel M., Loretz B., Steinfeld U., Lee H.H., Wenz G., Lehr Claus-Michael, ... , Schneider M., Philippi A.
(2014)
Polyester-idarubicin nanoparticles and a polymer-photosensitizer complex as potential drug formulations for cell-mediated drug delivery
International Journal of Pharmaceutics, 474 (1-2)
Author count: 9
Nafee N., Husari A., Maurer Christine K., Lu C., de Rossi C., Steinbach Anke, Hartmann Rolf W., ... , Lehr Claus-Michael, Schneider M.
(2014)
Antibiotic-free nanotherapeutics: Ultra-small, mucus-penetrating solid lipid nanoparticles enhance the pulmonary delivery and anti-virulence efficacy of novel quorum sensing inhibitors
Journal of Control Release
Author count: 5
Gomez-Mantilla J.D., Schaefer U.F., Casabo V.G., Lehr T., Lehr Claus-Michael
(2014)
Statistical comparison of dissolution profiles to predict the bioequivalence of extended release formulations
AAPS Journal, 16 (4)
Author count: 8
Salomon J.J., Muchitsch V.E., Gausterer J.C., Schwagerus E., Huwer H., Daum Nicole, ... , Lehr Claus-Michael, Ehrhardt C.
(2014)
The cell line NCl-H441 is a useful in vitro model for transport studies of human distal lung epithelial barrier
Molecular Pharmacology, 11 (3)
Author count: 3
Yamada H., Loretz B., Lehr Claus-Michael
(2014)
Design of starch-graft -PEI polymers: An effective and biodegradable gene delivery platform
Biomacromolecules, 15 (5)
Author count: 6
Ali H., Weigmann B., Neurath M.F., Collnot E.M., Windbergs Maike, Lehr Claus-Michael
(2014)
Budesonide loaded nanoparticles with pH-sensitive coating for improved mucosal targeting in mouse models of inflammatory bowel diseases
Journal of Control Release, 183 (1)
Author count: 2
Franzen L., Windbergs Maike
(2014)
Accessing Raman spectral variability in human stratum corneum for quantitative in vitro depth profiling
Journal of Raman Spectroscopy, 45 (1)
Author count: 10
Schrank S., Kann B., Saurugger E., Ehmann H., Werzer O., Windbergs Maike, Glasser B.J., Zimmer A., ... , Khinast J., Roblegg E.
(2014)
Impact of drying on solid state modifications and drug distribution in ibuprofen-loaded calcium stearate pellets
Molecular Pharmaceutics, 11 (2)
Author count: 10
Gantzsch S.P., Kann B., Ofer-Glaessgen M., Loos P., Berchtold H., Balbach S., Eichinger T., Lehr Claus-Michael, ... , Schaefer U.F., Windbergs Maike
(2014)
Characterization and evaluation of a modified PVPA barrier in comparison to Caco-2 cell monolayers for combined dissolution and permeation testing
Journal of Controlled Release, 175 (1)
Author count: 2
Hansen S., Lehr Claus-Michael
(2014)
Transfollicular delivery takes root: the future for vaccine design?
Expert Review of Vaccines, 13 (1)
Author count: 20
Bessems J.G., Loizou G., Krishnan K., Clewell H.J., Bernasconi C., Bois F., Coecke S., Collnot Eva Maria, Diembeck W., Farcal L.R., Geraets L., Gundert-Remy U., Kramer N., Küsters G., Leite S.B., Pelkonen O.R., Schröder K., Testai E., ... , Wilk-Zasadna I., Zaldivar-Comenges J.M.
(2014)
PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment. Recommendations from a joint EPAA - EURL ECVAM ADME workshop
Regulatory Toxicology and Pharmacology, 68 (1)
Author count: 5
Sterner B., Harms M., Weigandt M., Windbergs M., Lehr Claus-Michael
(2014)
Crystal suspensions of poorly soluble peptides for intra-articular application: A novel approach for biorelevant assessment of their in vitro release
International Journal of Pharmaceutics, 461 (1-2)
Author count: 3
Schleh C., Kreyling W.G., Lehr Claus-Michael
(2013)
Pulmonary surfactant is indispensable in order to simulate the in vivo situation
Particle and Fibre Toxicology, 10
Author count: 4
Gomez-Mantilla J.D., Casabo V.G., Schaefer U.F., Lehr Claus-Michael
(2013)
Permutation Test (PT) and Tolerated Difference Test (TDT): two new, robust and powerful nonparametric tests for statistical comparison of dissolution profiles
International Journal of Pharmacy, 441 (1-2)
Author count: 9
Mittal A., Raber A.S., Schaefer U.F., Weissmann S., Ebensen T., Schulze K., Guzmán C.A., ... , Hansen S., Lehr C.-M.
(2013)
Transfollicular delivery of antigen using nanocarriers for non-invasive transcutaneous immunization
Controlled Release Society (CRS) Letters, 30
Author count: 3
Franzen Lutz, Windbergs Maike, Hansen Steffi
(2012)
Assessment of near-infrared densitometry for in situ determination of the total stratum corneum thickness on pig skin: influence of storage time4
Skin Pharmacology and Physiology, 25 (5)
Author count: 4
Philippi C., Loretz B., Schaefer U.F., Lehr Claus-Michael
(2012)
Application of Chitosan for Anticancer Biopharmaceutical Delivery
Author count: 4
Muehlenfeld C., Kann Birthe, Windbergs Maike, Thommes M.
(2013)
Solid dispersions prepared by continuous cogrinding in an air jet mill
Journal of Pharmaceutical Sciences, 102 (11)
Author count: 7
Schrank S., Kann Birthe, Windbergs Maike, Glasser B.J., Zimmer A., ... , Khinast J., Roblegg E.
(2013)
Microstructure of calcium stearate matrix pellets: A function of the drying process
Journal of Pharmaceutical Sciences, 102 (11)
Author count: 3
Sigurdsson H.H., Kirch J., Lehr Claus-Michael
(2013)
Mucus as a barrier to lipophilic drugs
International Journal of Pharmaceutics, 453 (1)
Author count: 4
Mittal Ankit, Raber Anne S., Lehr Claus-Michael, Hansen Steffi
(2013)
Particle based vaccine formulations for transcutaneous immunization
Human Vaccines and Immunotherapeutics, 9 (9)
Author count: 5
Mostaghaci B., Loretz B., Haberkorn R., Kickelbick G., Lehr Claus-Michael
(2013)
One-step synthesis of nanosized and stable amino-functionalized calcium phosphate particles for DNA transfection
Chemistry of Materials, 25 (18)
Author count: 4
Faust D., Kletting Stephanie, Ueberham E., Dietrich C.
(2013)
Aryl hydrocarbon receptor-dependent cell cycle arrest in isolated mouse oval cells
Toxicology Letters, 223 (1)
Author count: 6
Windbergs Maike, Hansen Steffi, Schroeter A., Schaefer U.F., Lehr Claus-Michael, Bouwstra J.
(2013)
From the Structure of the Skin Barrier and Dermal Formulations to in vitro Transport Models for Skin Absorption: Skin Research in the Netherlands and in Germany
Skin Pharmacology and Physiology, 26 (4-6)
Author count: 10
Salomon J.J., Galeron P., Schulte N., Morow P.R., Severynse-Stevens D., Huwer H., Daum Nicole, Lehr Claus-Michael, ... , Hickey A.J., Ehrhardt C.
(2013)
Biopharmaceutical in vitro characterization of CPZEN-45, a drug candidate for inhalation therapy of tuberculosis
Therapeutic Delivery, 4 (8)
Author count: 3
Ruge A.C., Kirch J., Lehr Claus-Michael
(2013)
Pulmonary drug delivery: From generating aerosols to overcoming biological barriers-therapeutic possibilities and technological challenges
The Lancet Respiratory Medicine, 1
Author count: 4
Ali H., Collnot E.M., Windbergs Maike, Lehr Claus-Michael
(2013)
Nanomedicines for the treatment of inflammatory bowel diseases
European Journal of Nanomedicine, 5
Author count: 9
Mittal A., Raber A.S., Schaefer U.F., Weissmann S., Ebensen T., Schulze K., Guzmán C.A., ... , Lehr C.-M., Hansen S.
(2013)
Non-invasive delivery of nanoparticles to hair follicles: A perspective for transcutaneous immunization
Vaccine, 31 (34)
Author count: 4
Guillot Alexis, Limberge M., Krämer J., Lehr Claus-Michael
(2013)
In situ drug release monitoring with a fiber-optic system: Overcoming matrix interferences using derivative spectrophotometry
Dissolution Technologies, 20 (2)
Author count: 4
Windbergs Maike, Zhao Y., Heyman J., Weitz D.A.
(2013)
Biodegradable core-shell carriers for simultaneous encapsulation of synergistic actives
Journal of the American Chemical Society, 135 (21)
Author count: 5
Franzen L., Selzer D., Fluhr J.W., Schaefer U.F., Windbergs Maike
(2013)
Towards drug quantification in human skin with confocal Raman microscopy
European Journal of Pharmaceutics and Biopharmaceutics, 84 (2)
Author count: 8
Schneider M., Windbergs Maike, Daum Nicole, Loretz B., Collnot E.M., Hansen S., ... , Schaefer U.F., Lehr Claus-Michael
(2013)
Crossing biological barriers for advanced drug delivery
European Journal of Pharmaceutics and Biopharmaceutics, 84 (2)
Author count: 2
Kann B., Windbergs Maike
(2013)
Chemical imaging of drug delivery systems with structured surfaces-a combined analytical approach of confocal raman microscopy and optical profilometry
AAPS Journal, 15 (2)
Author count: 6
Herd H., Daum Nicole, Jones A.T., Huwer H., Ghandehari H., Lehr Claus-Michael
(2013)
Nanoparticle geometry and surface orientation influence mode of cellular uptake
ACS Nano, 7 (3)
Author count: 3
Hansen S., Lehr Claus-Michael, Schaefer U.F.
(2013)
Modeling the human skin barrier-Towards a better understanding of dermal absorption
Advanced Drug Delivery Reviews, 65 (2)
Author count: 3
Hansen S., Lehr Claus-Michael, Schaefer U.F.
(2013)
Improved input parameters for diffusion models of skin absorption
Advanced Drug Delivery Reviews, 65 (2)
Author count: 5
Franzen Lutz, Vidlarova L., Kostka K.H., Schaefer U.F., Windbergs M.
(2013)
Freeze-drying as a preserving preparation technique for in vitro testing of human skin
Experimental Dermatology, 22 (1)
Author count: 3
Labouta H.I., Schaefer U.F., Schneider M.
(2013)
Laser scanning microscopy approach for semiquantitation of in vitro dermal particle penetration
Methods in Molecular Biology, 961
Author count: 5
Kirch J., Guenther M., Schaefer U.F., Schneider M., Lehr Claus-Michael
(2012)
Computational fluid dynamics of nanoparticle disposition in the airways: mucus interactions and mucociliary clearance
Computing and Visualization in Science, 14 (7)
Author count: 6
Naegel A., Hahn T., Schaefer U.F., Lehr Claus-Michael, Heisig M., Wittum G.
(2012)
Finite dose skin penetration: a comparison of concentration-depth profiles from experiment and simulation
Computing and Visualization in Science, 165 (2)
Author count: 3
Collnot E.M., Ali H., Lehr Claus-Michael
(2012)
Nano- and microparticulate drug carriers for targeting of the inflamed intestinal mucosa
Journal of Controlled Release, 161 (2)
Author count: 5
Jacobs S., Bunt C.R., Wu Z., Lehr Claus-Michael, Rupenthal I.D.
(2012)
Characterization and evaluation of beta-glucan formulations as injectable implants for protein and peptide delivery
Drug Development and Industrial Pharmacy, 38 (11)
Author count: 8
Schmidt C., Lautenschlaeger C., Collnot E.M., Schumann M., Bojarski C., Schulzke J.D., ... , Lehr Claus-Michael, Stallmach A.
(2013)
Nano- and microscaled particles for drug targeting to inflamed intestinal mucosa-A first in vivo study in human patients
Journal of Controlled Release, 165 (2)
Author count: 9
Selzer D., Hahn T., Naegel A., Heisig M., Kostka K.H., Lehr Claus-Michael, Neumann D., ... , Schaefer U.F., Wittum G.
(2013)
Finite dose skin mass balance including the lateral part: Comparison between experiment, pharmacokinetic modeling and diffusion models
Journal of Controlled Release, 165 (2)
Author count: 10
Dandekar P., Jain R., Keil M., Loretz B., Muijs L., Schneider M., Auerbach D., Jung G., ... , Lehr Claus-Michael, Wenz G.
(2012)
Cellular delivery of polynucleotides by cationic cyclodextrin polyrotaxanes
Journal of Controlled Release, 164 (3)
Author count: 9
Kirch J., Schneider A., Abou B., Hopf A., Schaefer U.F., Schneider M., Schall C., ... , Wagner C., Lehr Claus-Michael
(2012)
Optical tweezers reveal relationship between microstructure and nanoparticle penetration of pulmonary mucus
Proceedings of the National Academy of Sciences USA, 109 (45)
Author count: 2
Seif S., Hansen Steffi
(2012)
Measuring the stratum corneum reservoir: Desorption kinetics from keratin
Journal of Pharmaceutical Sciences, 101 (10)
Author count: 7
Leonard F., Ali H., Collnot E.M., Crielaard B.J., Lammers T., ... , Storm G., Lehr Claus-Michael
(2012)
Screening of budesonide nanoformulations for treatment of inflammatory bowel disease in an inflamed 3D cell-culture model
ALTEX, 29 (3)
Author count: 5
May S., Jensen B., Wolkenhauer M., Schneider M., Lehr Claus-Michael
(2012)
Dissolution Techniques for In Vitro Testing of Dry Powders for Inhalation
Pharmaceutical Research, 29 (8)
Author count: 10
Ruge C.A., Schaefer U.F., Herrmann J., Kirch J., Canadas O., Echaide M., Perez-Gil J., Casals C., ... , Müller Rolf, Lehr Claus-Michael
(2012)
The interplay of lung surfactant proteins and lipids assimilates the macrophage clearance of nanoparticles
PLoS ONE, 7 (7)
Author count: 8
Dong M., Murdter T.E., Philippi C., Loretz B., Schaefer U.F., Lehr Claus-Michael, ... , Schwab M., Ammon-Treiber S.
(2012)
Pulmonary delivery and tissue distribution of aerosolized antisense 2'-O-Methyl RNA containing nanoplexes in the isolated perfused and ventilated rat lung
European Journal of Pharmaceutics and Biopharmaceutics, 81 (3)
Author count: 7
Schaefer J., Schulze C., Marxer E.E., Schaefer U.F., Wohlleben W., ... , Bakowsky U., Lehr Claus-Michael
(2012)
Atomic force microscopy and analytical ultracentrifugation for probing nanomaterial protein interactions
ACS Nano, 6 (6)
Author count: 6
Kohler D., Schneider M., Lehr Claus-Michael, Krüger M., Möhwald H., Wang D.
(2012)
Preparation of elongated polyelectrolyte particles from particles
European Cells and Materials, 20 (Suppl. 3)
Author count: 7
Kirch J., Guenther M., Doshi N., Schaefer U.F., Schneider M., ... , Mitragotri S., Lehr Claus-Michael
(2012)
Mucociliary clearance of micro- and nanoparticles is independent of size, shape and charge--an ex vivo and in silico approach
Journal of Controlled Release, 159 (1)
Author count: 6
Hahn T., Selzer D., Neumann D., Kostka K.H., Lehr Claus-Michael, Schaefer U.F.
(2012)
Influence of the application area on finite dose permeation in relation to drug type applied
Experimental Dermatology, 21 (3)
Author count: 7
Nafee N., Schneider M., Friebel K., Dong M., Schaefer U.F., ... , Murdter T.E., Lehr Claus-Michael
(2012)
Treatment of lung cancer via telomerase inhibition: self-assembled nanoplexes versus polymeric nanoparticles as vectors for 2'-O-Methyl-RNA
European Journal of Pharmaceutics and Biopharmaceutics, 80 (3)
Author count: 2
Hansen S., Lehr Claus-Michael
(2012)
Nanoparticles for transcutaneous vaccination
Microbial Biotechnology, 5 (2)
Author count: 7
Dandekar P., Jain R., Stauner T., Loretz B., Koch M., ... , Wenz G., Lehr Claus-Michael
(2012)
A hydrophobic starch polymer for nanoparticle-mediated delivery of docetaxel
Macromolecular Bioscience, 12 (2)
Author count: 16
Krejci I., Piana C., Howitz S., Wegener T., Fiedler S., Zwanzig M., Schmitt D., Daum N., Meier K., Lehr Claus-Michael*, Batista U., Zemljic S., Messerschmidt J., Franzke J., ... , Wirth M., Gabor F.
(2011)
Process optimization and biocompatibility of cell carriers suitable for automated magnetic manipulation
Acta Biomaterialia, 8 (3)
Author count: 9
Ourique A.F., Melero A., de Bona da Silva C., Schaefer U.F., Pohlmann A.R., Guterres S.S., Lehr Claus-Michael*, ... , Kostka K.H., Beck R.C.
(2011)
Improved photostability and reduced skin permeation of tretinoin: development of a semisolid nanomedicine
European Journal of Pharmaceutics and Biopharmaceutics, 79 (1)
Author count: 7
Linn M., Collnot E.M., Djuric D., Hempel K., Fabian E., ... , Kolter K., Lehr Claus-Michael
(2012)
Soluplus(R) as an effective absorption enhancer of poorly soluble drugs in vitro and in vivo
European Journal of Pharmaceutical Sciences, 45 (3)
Author count: 8
Ruge C.A., Kirch J., Canadas O., Schneider M., Perez-Gil J., Schaefer U.F., ... , Casals C., Lehr Claus-Michael*
(2011)
Uptake of nanoparticles by alveolar macrophages is triggered by surfactant protein A
Nanomedicine, 7 (6)
Author count: 4
Daum Nicole, Tscheka C., Neumeyer A., Schneider M.
(2012)
Novel approaches for drug delivery systems in nanomedicine: effects of particle design and shape
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 4 (1)
Author count: 6
Daum N., Kuehn A., Hein S., Schaefer U.F., Huwer H., Lehr Claus-Michael
(2012)
Isolation, cultivation, and application of human alveolar epithelial cells
Methods in Molecular Biology, 806
Author count: 11
Dong M., Philippi C., Loretz B., Nafee N., Schaefer U.F., Friedel G., Ammon-Treiber S., Griese E.U., Lehr Claus-Michael*, ... , Klotz U., Murdter T.E.
(2011)
Tissue slice model of human lung cancer to investigate telomerase inhibition by nanoparticle delivery of antisense 2'-O-methyl-RNA
International Journal of Pharmaceutics, 419 (1-2)
Author count: 8
Jain R., Dandekar P., Loretz B., Melero A., Stauner T., Wenz G., ... , Koch M., Lehr Claus-Michael*
(2011)
Enhanced cellular delivery of idarubicin by surface modification of propyl starch nanoparticles employing pteroic acid conjugated polyvinyl alcohol
International Journal of Pharmaceutics, 420 (1)
Author count: 2
Hansen S., Lehr Claus-Michael*
(2011)
Using nanoparticles in the skin? More than just cosmetics! [Mit Nanopartikeln in die Haut? Mehr als nur Kosmetik!]
Deutsche Apotheker Zeitung, 151 (27)
Author count: 3
Collnot E.-M., Mell N.A., Lehr Claus-Michael*
(2011)
New hope for inflammatory bowel disease [Neue Hoffnung bei entzündlicher Darmerkrankung]
Deutsche Apotheker Zeitung, 151 (27)
Author count: 5
Neumeyer A., Bukowski M., Veith M., Lehr Claus-Michael*, Daum N.
(2011)
Propidium iodide labeling of nanoparticles as a novel tool for the quantification of cellular binding and uptake
Nanomedicine, 7 (4)
Author count: 3
Guevel X.L., Daum Nicole*, Schneider M.
(2011)
Synthesis and characterization of human transferrin-stabilized gold nanoclusters
Nanotechnology, 22 (27)
Author count: 5
Hankin S., Boraschi D., Duschl A., Lehr Claus-Michael*, Lichtenbeld H.
(2011)
Towards nanotechnology regulation - Publish the unpublishable
Nano Today, 6 (3)
Author count: 6
Kohler D., Schneider M., Kruger M., Lehr Clauch-Michael*, Mohwald H., Wang D.
(2011)
Template-assisted polyelectrolyte encapsulation of nanoparticles into dispersible, hierarchically nanostructured microfibers
Advanced Materials, 23 (11)
Author count: 5
Neumeyer A., Bukowski M., Veith M., Lehr Claus-Michael*, Daum N.
(2010)
Interaction of nanoparticles and cells - cellular uptake and cytotoxic effects in vitro
Author count: 4
Hein S., Bur M., Schaefer U.F., Lehr Claus-Michael*
(2011)
A new Pharmaceutical Aerosol Deposition Device on Cell Cultures (PADDOCC) to evaluate pulmonary drug absorption for metered dose dry powder formulations
European Journal of Pharmacology and Biopharmacology, 77 (1)
Author count: 8
Patzelt A., Richter H., Knorr F., Schafer U., Lehr Claus-Michael*, Dahne L., ... , Sterry W., Lademann J.
(2011)
Selective follicular targeting by modification of the particle sizes
Journal of Control Release, 150 (1)
Author count: 5
Breitkreutz D., Braiman-Wiksman L., Daum N.*, Denning M.F., Tennenbaum T.
(2007)
Protein kinase C family: on the crossroads of cell signaling in skin and tumor epithelium
Journal of Cancer Research and Clinical Oncology, 133 (11)
Author count: 5
Schulze C., Schaefer U.F., Ruge C.A., Wohlleben W., Lehr Claus-Michael*
(2011)
Interaction of metal oxide nanoparticles with lung surfactant protein A
European Journal of Pharmaceutics and Biopharmaceutics, 77 (3)
Author count: 4
Hansen Steffi*, Selzer D., Schaefer U.F., Kasting G.B.
(2011)
An extended database of keratin binding
Journal of Pharmaceutical Sciences, 100 (5)
Author count: 6
Lehmann A.D., Daum N., Bur M., Lehr Claus-Michael*, Gehr P., Rothen-Rutishauser B.M.
(2011)
An in vitro triple cell co-culture model with primary cells mimicking the human alveolar epithelial barrier
European Journal of Pharmaceutics and Biopharmaceutics, 77 (3)
Author count: 6
Reum N., Fink-Straube C., Klein T., Hartmann R.W.*, Lehr Claus-Michael*, Schneider M.
(2010)
Multilayer coating of gold nanoparticles with drug-polymer coadsorbates
Langmuir, 26 (22)
Author count: 3
Leonard F., Collnot E.M., Lehr Claus-Michael*
(2010)
A three-dimensional coculture of enterocytes, monocytes and dendritic cells to model inflamed intestinal mucosa in vitro
Molecular Pharmaceutics, 7 (6)
Author count: 4
Philippi C., Loretz B., Schaefer U.F., Lehr Claus-Michael*
(2010)
Telomerase as an emerging target to fight cancer - Opportunities and challenges for nanomedicine
Journal of Controlled Release, 146 (2)
Author count: 8
Muendoerfer M., Schaefer U.F., Koenig P., Walk J.S., Loos P., Balbach S., ... , Eichinger T., Lehr Claus-Michael*
(2010)
Online monitoring of transepithelial electrical resistance (TEER) in an apparatus for combined dissolution and permeation testing
International Journal of Pharmaceutics, 392 (1-2)