Author count: 14
Reichardt C., Brandt S., Bernhardt A., Krause A., Lindquist J.A., Weinert S., Geffers R., Franz T., Kahlfuss S., Dudeck A., Mathew A., Rana R., ... , Isermann B., Mertens P.R.
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DNA-binding protein-A promotes kidney ischemia/reperfusion injury and participates in mitochondrial function
Kidney Int.
Author count: 14
Brandt S., Bernhardt A., Häberer S., Wolters K., Gehringer F., Reichardt C., Krause A., Geffers R., Kahlfuß S., Jeron A., Bruder D., Lindquist J.A., ... , Isermann B., Mertens P.R.
(2024)
Comparative Analysis of Acute Kidney Injury Models and Related Fibrogenic Responses: Convergence on Methylation Patterns Regulated by Cold Shock Protein
Cells,
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Author count: 23
Froese N., Szaroszyk M., Galuppo P., Visker J.R., Werlein C., Korf-Klingebiel M., Berliner D., Reboll M.R., Hamouche R., Gegel S., Wang Y., Hofmann W., Tang M., Geffers R., Wende A.R., K++hnel M.P., Jonigk D.D., Hansmann G., Wollert K.C., Abel E.D., Drakos S.G., ... , Bauersachs J., Riehle C.
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Hypoxia Attenuates Pressure Overload-Induced Heart Failure
Journal of the American Heart Association,
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Author count: 4
Fraccarollo D., Geffers R., Galuppo P., Bauersachs J.
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Mineralocorticoid receptor promotes cardiac macrophage inflammaging
Basic Res.Cardiol.
Author count: 30
Manoharan J., Rana R., Kuenze G., Gupta D., Elwakiel A., Ambreen S., Wang H., Banerjee K., Zimmermann S., Singh K., Gupta A., Fatima S., Kretschmer S., Schaefer L., Zeng-Brouwers J., Schwab C., Al-Dabet M.M., Gadi I., Altmann H., Koch T., Poitz D.M., Baber R., Kohli S., Shahzad K., Geffers R., Lee-Kirsch M.A., Kalinke U., Meiler J., ... , Mackman N., Isermann B.
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Tissue factor binds to and inhibits interferon-a[alpha] receptor 1 signaling
Immunity.,
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Author count: 12
Abberger H., Hose M., Ninnemann A., Menne C., Eilbrecht M., Lang K.S., Matuschewski K., Geffers R., Herz J., Buer J., ... , Westendorf A.M., Hansen W.
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Neuropilin-1 identifies a subset of highly activated CD8+ T cells during parasitic and viral infections
PLoS Pathog,
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Author count: 17
Weber C.A.M., Krönke N., Volk V., Auber B., Förster A., Trost D., Geffers R., Esmaeilzadeh M., Lalk M., Nabavi A., Samii A., Krauss J.K., Feuerhake F., Hartmann C., Wiese B., ... , Brand F., Weber R.G.
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Rare germline variants in POLE and POLD1 encoding the catalytic subunits of DNA polymerases e[epsilon] and d[delta] in glioma families
Acta Neuropathol.Commun.,
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Author count: 14
Werfel L., Martens H., Hennies I., Gjerstad A.C., Fröde K., Altarescu G., Banerjee S., Valenzuela Palafoll I., Geffers R., Kirschstein M., Christians A., Bjerre A., ... , Haffner D., Weber R.G.
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Diagnostic Yield and Benefits of Whole Exome Sequencing in CAKUT Patients Diagnosed in the First Thousand Days of Life
Kidney Intl.Rep.
Author count: 13
Vogel K., Arra A., Lingel H., Bretschneider D., Prätsch F., Schanze D., Zenker M., Balk S., Bruder D., Geffers R., Hachenberg T., ... , Arens C., Brunner-Weinzierl M.C.
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Bifidobacteria shape antimicrobial T-helper cell responses during infancy and adulthood
Nat.Commun.,
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Author count: 9
Mohan K., Gasparoni G., Salhab A., Orlich M.M., Geffers R., Hoffmann S., Adams R.H., ... , Walter J., Nordheim A.
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Age-Associated Changes in Endothelial Transcriptome and Epigenetic Landscapes Correlate With Elevated Risk of Cerebral Microbleeds
J.Am.Heart Assoc.
Author count: 6
Zelenka L., Jarek M., Pägelow D., Geffers R., van Vorst K., Fulde M.
(2023)
Crosstalk of Highly Purified Microglia and Astrocytes in the Frame of Toll-like Receptor (TLR)2/1 Activation
Neuroscience,
526
(August 2023)
Author count: 14
Bernhardt A., Krause A., Reichardt C., Steffen H., Isermann B., Völker U., Hammer E., Geffers R., Phillipsen L., Dhjamandi K., Ahmad S., Brandt S., ... , Lindquist J.A., Mertens P.R.
(2023)
Excessive sodium chloride ingestion promotes inflammation and kidney fibrosis in aging mice
Am.J.Physiol Cell Physiol
Author count: 15
Bufe S., Zimmermann A., Ravens S., Prinz I., Buitrago-Molina L.E., Geffers R., Woller N., Kühnel F., Talbot S.R., Noyan F., Manns M.P., Wedemeyer H., Hardtke-Wolenski M., ... , Jaeckel E., Davalos-Misslitz A.C.
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PD-1/CTLA-4 Blockade Leads to Expansion of CD8(+)PD-1(int) TILs and Results in Tumor Remission in Experimental Liver Cancer
Liver Cancer,
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Author count: 12
Herppich S., Hoenicke L., Kern F., Kruse F., Smout J., Greweling-Pils M.C., Geffers R., Burton O.T., Liston A., Keller A., ... , Floess S., Huehn J.
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Zfp362 potentiates murine colonic inflammation by constraining Treg cell function rather than promoting Th17 cell differentiation
Eur.J.Immunol.
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Münch P.C., Eberl C., Woelfel S., Ring D., Fritz A., Herp S., Lade I., Geffers R., Franzosa E.A., Huttenhower C., ... , McHardy A.C., Stecher B.
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Pulsed antibiotic treatments of gnotobiotic mice manifest in complex bacterial community dynamics and resistance effects
Cell Host.Microbe,
31
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Author count: 29
Kruse B., Buzzai A.C., Shridhar N., Braun A.D., Gellert S., Knauth K., Pozniak J., Peters J., Dittmann P., Mengoni M., van der Sluis T.C., Höhn S., Antoranz A., Krone A., Fu Y., Yu D., Essand M., Geffers R., Mougiakakos D., Kahlfuß S., Kashkar H., Gaffal E., Bosisio F.M., Bechter O., Rambow F., Marine J.C., Kastenmüller W., ... , Müller A.J., Tüting T.
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CD4+ T cell-induced inflammatory cell death controls immune-evasive tumours
Nature
Author count: 25
Zhang B., Zhang Z., Koeken V.A.C.M., Kumar S., Aillaud M., Tsay H.C., Liu Z., Kraft A.R.M., Soon C.F., Odak I., Bosnjak B., Vlot A., Swertz M.A., Ohler U., Geffers R., Illig T., Hühn J., Saliba A.E., Sander L.E., Förster R., Xu C.J., Cornberg M., Schulte L.N., ... , Li Y., Deutsche C.O.V.I.
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Altered and allele-specific open chromatin landscape reveals epigenetic and genetic regulators of innate immunity in COVID-19
Cell Genom.
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Froese N., Szaroszyk M., Korf-Klingebiel M., Koch K., Schmitto J.D., Geffers R., Hilfiker-Kleiner D., Riehle C., Wollert K.C., ... , Bauersachs J., Heineke J.
(2022)
Endothelial Cell GATA2 Modulates the Cardiomyocyte Stress Response through the Regulation of Two Long Non-Coding RNAs
Biology,
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Author count: 11
Kopejtka K., Tomasch J., Kaftan D., Gardiner A.T., Bína D., Gardian Z., Bellas C., Dröge A., Geffers R., ... , Sommaruga R., Koblílek M.
(2022)
A bacterium from a mountain lake harvests light using both proton-pumping xanthorhodopsins and bacteriochlorophyll-based photosystems
Proc.Natl.Acad.Sci.U.S.A.,
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Author count: 8
Pinel-Cabello M., Jauregui R., Jroundi F., Geffers R., Jarek M., Link A., ... , Vilchez-Vargas R., Merroun M.L.
(2022)
Genetic mechanisms for Se(VI) reduction and synthesis of trigonal 1-D nanostructures in Stenotrophomonas bentonitica: Perspectives in eco-friendly nanomaterial production and bioremediation
Sci.Total Environ.,
862
Author count: 20
Naasner L., Froese N., Hofmann W., Galuppo P., Werlein C., Shymotiuk I., Szaroszyk M., Erschow S., Amanakis G., Bähre H., Kühnel M.P., Jonigk D.D., Geffers R., Seifert R., Ricke-Hoch M., Wende A.R., Blaner W.S., Abel E.D., ... , Bauersachs J., Riehle C.
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Vitamin A Preserves Cardiac Energetic Gene Expression in a Murine Model of Diet-Induced Obesity
Am.J Physiol Heart Circ.Physiol
Author count: 7
Kircher B., Woltemate S., Gutzki F., Schlüter D., Geffers R., ... , Bähre H., Vital M.
(2022)
Predicting butyrate- and propionate-forming bacteria of gut microbiota from sequencing data
Gut Microbes,
14
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Author count: 19
Riese P., Trittel S., Akmatov M.K., May M., Prokein J., Illig T., Schindler C., Sawitzki B., Elfaki Y., Floess S., Huehn J., Blazejewski A.J., Strowig T., Hernandez-Vargas E.A., Geffers R., Zhang B., Li Y., ... , Pessler F., Guzmán C.A.
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Distinct immunological and molecular signatures underpinning influenza vaccine responsiveness in the elderly
Nat.Commun.,
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Author count: 12
Wenzek C., Steinbach P., Wirsdörfer F., Sutter K., Boehme J.D., Geffers R., Klopfleisch R., Bruder D., Jendrossek V., Buer J., ... , Westendorf A.M., Knuschke T.
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CD47 restricts antiviral function of alveolar macrophages during influenza virus infection
iScience,
25
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Author count: 20
Christians A., Kesdiren E., Hennies I., Hofmann A., Trowe M.O., Brand F., Martens H., Gjerstad A.C., Gucev Z., Zirngibl M., Geffers R., Seeman T., Billing H., Bjerre A., Tasic V., Kispert A., Ure B., Haffner D., ... , Dingemann J., Weber R.G.
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Heterozygous variants in the DVL2 interaction region of DACT1 cause CAKUT and features of Townes-Brocks syndrome 2
Hum.Genet.
Author count: 9
Chludzinski E., Klemens J., Ciurkiewicz M., Geffers R., Pöpperl P., Stoff M., Shin D.L., ... , Herrler G., Beineke A.
(2022)
Phenotypic and Transcriptional Changes of Pulmonary Immune Responses in Dogs Following Canine Distemper Virus Infection
Int.J.Mol.Sci.,
23
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Author count: 8
Li Z., Geffers R., Jain G., Klawonn F., Kökpinar Ö., Nimtz M., ... , Schmidt-Heck W., Rinas U.
(2021)
Transcriptional network analysis identifies key elements governing the recombinant protein production provoked reprogramming of carbon and energy metabolism in Escherichia coli BL21 (DE3)
Engineering Reports,
3
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Author count: 15
Li S., Lu C.W., Diem E.C., Li W., Guderian M., Lindenberg M., Kruse F., Buettner M., Floess S., Winny M.R., Geffers R., Richnow H.H., Abraham W.R., ... , Grassl G.A., Lochner M.
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Acetyl-CoA-Carboxylase 1-mediated de novo fatty acid synthesis sustains Lgr5+ intestinal stem cell function
Nat.Commun.,
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Author count: 25
Al-Dabet M.M., Shahzad K., Elwakiel A., Sulaj A., Kopf S., Bock F., Gadi I., Zimmermann S., Rana R., Krishnan S., Gupta D., Manoharan J., Fatima S., Nazir S., Schwab C., Baber R., Scholz M., Geffers R., Mertens P.R., Nawroth P.P., Griffin J.H., Keller M., Dockendorff C., ... , Kohli S., Isermann B.
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Reversal of the renal hyperglycemic memory in diabetic kidney disease by targeting sustained tubular p21 expression
Nat.Commun.,
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Author count: 7
Lonnemann N., Hosseini S., Ohm M., Geffers R., Hiller K., ... , Dinarello C.A., Korte M.
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IL-37 expression reduces acute and chronic neuroinflammation and rescues cognitive impairment in an Alzheimer's disease mouse model
eLife,
11
Author count: 15
Waqas S.F., Sohail A., Nguyen A.H.H., Usman A., Ludwig T., Wegner A., Malik M.N.H., Schuchardt S., Geffers R., Winterhoff M., Merkert S., Martin U., Olmer R., ... , Lachmann N., Pessler F.
(2022)
ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives
Clin.Transl.Med.,
12
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Author count: 25
He W., Henne A., Lauterbach M., Geißmar E., Nikolka F., Kho C., Heinz A., Dostert C., Grusdat M., Cordes T., Härm J., Goldmann O., Ewen A., Verschueren C., Blay-Cadanet J., Geffers R., Garritsen H., Kneiling M., Holm C.K., Metallo C.M., Medina E., Abdullah Z., Latz E., ... , Brenner D., Hiller K.
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Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages
Nat.Metab,
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Author count: 15
Riehle C., Sieweke J.T., Bakshi S., Ha C.M., Junker Udesen N.L., Moller-Helgestad O.K., Froese N., Berg Ravn H., Bähre H., Geffers R., Seifert R., Moller J.E., Wende A.R., ... , Bauersachs J., Schäfer A.
(2022)
miRNA-200b-A Potential Biomarker Identified in a Porcine Model of Cardiogenic Shock and Mechanical Unloading
Front Cardiovasc.Med.,
9
Author count: 17
Hochnadel I., Hoenicke L., Petriv N., Neubert L., Reinhard E., Hirsch T., Alfonso J.C.L., Suo H., Longerich T., Geffers R., Lichtinghagen R., Guzmán C.A., Wedemeyer H., Lenzen H., Manns M.P., ... , Bruder D., Yevsa T.
(2022)
Correction: Safety and efficacy of prophylactic and therapeutic vaccine based on live-attenuated Listeria monocytogenes in hepatobiliary cancers (Oncogene, (2022), 41, 14, (2039-2053), 10.1038/s41388-022-02222-z)
Oncogene,
41
(19)
Author count: 24
Froese N., Cordero J., Abouissa A., Trogisch F.A., Grein S., Szaroszyk M., Wang Y., Gigina A., Korf-Klingebiel M., Bosnjak B., Davenport C.F., Wiehlmann L., Geffers R., Riechert E., Jürgensen L., Boileau E., Lin Y., Dieterich C., Förster R., Bauersachs J., Ola R., Dobreva G., ... , Völkers M., Heineke J.
(2022)
Analysis of myocardial cellular gene expression during pressure overload reveals matrix based functional intercellular communication
iScience,
25
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Author count: 12
Kreutzer F.P., Meinecke A., Mitzka S., Hunkler H.J., Hobuß L., Abbas N., Geffers R., Weusthoff J., Xiao K., Jonigk D.D., ... , Fiedler J., Thum T.
(2022)
Development and characterization of anti-fibrotic natural compound similars with improved effectivity
Basic Res.Cardiol.,
117
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Author count: 15
Ebert K., Haffner I., Zwingenberger G., Keller S., Raimundez E., Geffers R., Wirtz R., Barbaria E., Hollerieth V., Arnold R., Walch A., Hasenauer J., Maier D., ... , Lordick F., Luber B.
(2022)
Combining gene expression analysis of gastric cancer cell lines and tumor specimens to identify biomarkers for anti-HER therapies -
BMC Cancer,
22
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Author count: 17
Hochnadel I., Hoenicke L., Petriv N., Neubert L., Reinhard E., Hirsch T., Alfonso J.C.L., Suo H., Longerich T., Geffers R., Lichtinghagen R., Guzmán C.A., Wedemeyer H., Lenzen H., Manns M.P., ... , Bruder D., Yevsa T.
(2022)
Safety and efficacy of prophylactic and therapeutic vaccine based on live-attenuated Listeria monocytogenes in hepatobiliary cancers
Oncogene
Author count: 8
Schäfer F., Görner P., Woltemate S., Brandenberger C., Geffers R., Ziesing S., ... , Schlüter D., Vital M.
(2022)
The Resistance Mechanism Governs Physiological Adaptation of Escherichia coli to Growth With Sublethal Concentrations of Carbapenem
Front.Microbiol.,
12
Author count: 20
Krone A., Fu Y., Schreiber S., Kotrba J., Borde L., Nötzold A., Thurm C., Negele J., Franz T., Stegemann-Koniszewski S., Schreiber J., Garbers C., Shukla A., Geffers R., Schraven B., Reinhold D., Dudeck A., Reinhold A., ... , Müller A.J., Kahlfuss S.
(2022)
Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc
Sci.Rep.,
12
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Author count: 8
Radmanesh H., Liu D., Geffers R., Shandiz F.H., Sadr-Nabavi A., Hillemanns P., ... , Park-Simon T.W., Dörk T.
(2022)
Exome sequencing identifies RASSF1 and KLK3 germline variants in an Iranian multiple-case breast cancer family
Eur.J.Med.Genet.,
65
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Author count: 39
Szaroszyk M., Kattih B., Martin-Garrido A., Trogisch F.A., Dittrich G.M., Grund A., Abouissa A., Derlin K., Meier M., Holler T., Korf-Klingebiel M., Völker K., Garfias Macedo T., Pablo Tortola C., Boschmann M., Huang N., Froese N., Zwadlo C., Malek Mohammadi M., Luo X., Wagner M., Cordero J., Geffers R., Batkai S., Thum T., Bork N., Nikolaev V.O., Müller O.J., Katus H.A., El-Armouche A., Kraft T., Springer J., Dobreva G., Wollert K.C., Fielitz J., von Haehling S., Kuhn M., ... , Bauersachs J., Heineke J.
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Skeletal muscle derived Musclin protects the heart during pathological overload
Nat.Commun.,
13
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Author count: 63
Wendisch D., Dietrich O., Mari T., von Stillfried S., Ibarra I.L., Mittermaier M., Mache C., Chua R.L., Knoll R., Timm S., Brumhard S., Krammer T., Zauber H., Hiller A.L., Pascual-Reguant A., Mothes R., Bülow R.D., Schulze J., Leipold A.M., Djudjaj S., Erhard F., Geffers R., Pott F., Kazmierski J., Radke J., Pergantis P., Baßler K., Conrad C., Aschenbrenner A.C., Sawitzki B., Landthaler M., Wyler E., Horst D., Hippenstiel S., Hocke A., Heppner F.L., Uhrig A., Garcia C., Machleidt F., Herold S., Elezkurtaj S., Thibeault C., Witzenrath M., Cochain C., Suttorp N., Drosten C., Goffinet C., Kurth F., Schultze J.L., Radbruch H., Ochs M., Eils R., Müller-Redetzky H., Hauser A.E., Luecken M.D., Theis F.J., Conrad C., Wolff T., Boor P., Selbach M., Saliba A.E., ... , Sander L.E., Deutsche C.O.V.I.
(2021)
SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis
Cell,
184
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Author count: 7
Waindok P., Janecek-Erfurth E., Lindenwald D.L., Wilk E., Schughart K., ... , Geffers R., Strube C.
(2022)
Toxocara canis-and Toxocara cati-Induced Neurotoxocarosis Is Associated with Comprehensive Brain Transcriptomic Alterations
Microorg.,
10
(1)
Author count: 21
Sohail A., Iqbal A.A., Sahini N., Chen F., Tantawy M., Waqas F., Winterhoff M., Ebensen T., Schultz K., Geffers R., Schughart K., Preusse M., Shehata M., Bähre H., Pils M.C., Guzmán C.A., Mostafa A., Pleschka S., Falk C., ... , Michelucci A., Pessler F.
(2022)
Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection
PLoS Pathog.,
18
(1)
Author count: 8
Quentmeier H., Geffers R., Hauer V., Nagel S., Pommerenke C., Uphoff C.C., ... , Zaborski M., Drexler H.G.
(2022)
Inhibition of MCL1 induces apoptosis in anaplastic large cell lymphoma and in primary effusion lymphoma
Sci.Rep.,
12
(1)
Author count: 21
Malik M.N.H., Waqas S.F.H., Zeitvogel J., Cheng J., Geffers R., Gouda Z.A., Elsaman A.M., Radwan A.R., Schefzyk M., Braubach P., Auber B., Olmer R., Müsken M., Roesner L.M., Gerold G., Schuchardt S., Merkert S., Martin U., Meissner F., ... , Werfel T., Pessler F.
(2021)
Congenital deficiency reveals critical role of ISG15 in skin homeostasis
J.Clin.Invest
Author count: 8
Dietrich O., Heinz A., Goldmann O., Geffers R., Beineke A., Hiller K., ... , Saliba A.E., Medina E.
(2021)
Dysregulated Immunometabolism Is Associated with the Generation of Myeloid-Derived Suppressor Cells in Staphylococcus aureus Chronic Infection
J.Innate.Immun.
Author count: 13
Preuß E.B., Schubert S., Werlein C., Stark H., Braubach P., Höfer A., Plucinski E.K.J., Shah H.R., Geffers R., Sewald K., Braun A., ... , Jonigk D.D., Kühnel M.P.
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The challenge of long-term cultivation of human precision-cut lung slices
Am.J.Pathol.
Author count: 14
Kunzke T., Hölzl F.T., Prade V.M., Buck A., Huber K., Feuchtinger A., Ebert K., Zwingenberger G., Geffers R., Hauck S.M., Haffner I., Luber B., ... , Lordick F., Walch A.
(2021)
Metabolomic therapy response prediction in pretherapeutic tissue biopsies for trastuzumab in patients with HER2-positive advanced gastric cancer
Clin.Transl.Med.,
11
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Author count: 9
Ramli S.R., Bunk B., Spröer C., Geffers R., Jarek M., Bhuju S., Goris M., ... , Mustakim S., Pessler F.
(2021)
Complete genome sequencing of leptospira interrogans isolates from malaysia reveals massive genome rearrangement but high conservation of virulence-associated genes
Pathogens,
10
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Author count: 12
Schütte K., Schulz C., Vilchez-Vargas R., Vasapolli R., Palm F., Simon B., Schomburg D., Lux A., Geffers R., Pieper D.H., ... , Link A., Malfertheiner P.
(2021)
Impact of healthy aging on active bacterial assemblages throughout the gastrointestinal tract
Gut Microbes,
13
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Author count: 16
Adamczyk A., Pastille E., Kehrmann J., Vu V.P., Geffers R., Wasmer M.H., Kasper S., Schuler M., Lange C.M., Muggli B., Rau T.T., Klein D., Hansen W., Krebs P., ... , Buer J., Westendorf A.M.
(2021)
GPR15 facilitates recruitment of regulatory T cells to promote colorectal cancer
Cancer Res.,
81
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Author count: 13
Mohammadi M.M., Abouissa A., Azizah I., Xie Y., Cordero J., Shirvani A., Gigina A., Engelhardt M., Trogisch F.A., Geffers R., Dobreva G., ... , Bauersachs J., Heineke J.
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Induction of cardiomyocyte proliferation and angiogenesis protects neonatal mice from pressure overload-associated maladaptation
JCI Insight,
4
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Author count: 17
Dittrich G.M., Froese N., Wang X., Kroeger H., Wang H., Szaroszyk M., Malek-Mohammadi M., Cordero J., Keles M., Korf-Klingebiel M., Wollert K.C., Geffers R., Mayr M., Conway S.J., Dobreva G., ... , Bauersachs J., Heineke J.
(2021)
Fibroblast GATA-4 and GATA-6 promote myocardial adaptation to pressure overload by enhancing cardiac angiogenesis
Basic Res.Cardiol.,
116
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Author count: 20
Gadi I., Fatima S., Elwakiel A., Nazir S., Mohanad Al-Dabet M., Rana R., Bock F., Manoharan J., Gupta D., Biemann R., Nieswandt B., Braun-Dullaeus R., Besler C., Scholz M., Geffers R., Griffin J.H., Esmon C.T., Kohli S., ... , Isermann B., Shahzad K.
(2021)
Different DOACs Control Inflammation in Cardiac Ischemia-Reperfusion Differently
Circ Res,
128
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Author count: 18
Stahnke S., Döring H., Kusch C., De Gorter D.J.J., Dütting S., Guledani A., Pleines I., Schnoor M., Sixt M., Geffers R., Rohde M., Müsken M., Kage F., Steffen A., Faix J., Nieswandt B., ... , Rottner K., Stradal T.E.B.
(2021)
Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion
Curr.Biol.,
31
(5 / May)
Author count: 16
Etzrodt V., Idowu T.O., Schenk H., Seeliger B., Prasse A., Thamm K., Pape T., Müller-Deile J., van Meurs M., Thum T., Garg A., Geffers R., Stahl K., Parikh S.M., ... , Haller H., David S.
(2021)
Role of endothelial microRNA 155 on capillary leakage in systemic inflammation
Crit Care,
25
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Author count: 7
Ibánez A., Bletz M.C., Quezada G., Geffers R., Jarek M., ... , Vences M., Steinfartz S.
(2021)
No impact of a short-term climatic "El Niño" fluctuation on gut microbial diversity in populations of the Galapagos marine iguana (Amblyrhynchus cristatus)
Sci.Nat.,
108
(1)
Author count: 9
Sabino-Pinto J., Bletz M.C., Islam M.M., Shimizu N., Bhuju S., Geffers R., Jarek M., ... , Kurabayashi A., Vences M.
(2021)
Correction to: Composition of the Cutaneous Bacterial Community in Japanese Amphibians: Effects of Captivity, Host Species, and Body Region (Microbial Ecology, (2016), 72, 2, (460-469), 10.1007/s00248-016-0797-6)
Microb.Ecol.
Author count: 15
Buitrago-Molina L.E., Marhenke S., Becker D., Geffers R., Itzel T., Teufel A., Jaeschke H., Lechel A., Unger K., Markovic J., Sharma A.D., Marquardt J.U., Saborowski M., ... , Saborowski A., Vogel A.
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p53-independent induction of p21 fails to control regeneration and hepatocarcinogenesis in a murine liver injury model
Cell Mol.Gastroenterol.Hepatol.,
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Dubich T., Dittrich A., Bousset K., Geffers R., Büsche G., Köster M., Hauser H., ... , Schulz T.F., Wirth D.
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3D culture conditions support Kaposi's sarcoma herpesvirus (KSHV) maintenance and viral spread in endothelial cells
J.Mol.Med.(Berl),
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Pellegrino R., Thavamani A., Calvisi D.F., Budczies J., Neumann A., Geffers R., Kroemer J., Greule D., Schirmacher P., ... , Nordheim A., Longerich T.
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Serum Response Factor (SRF) Drives the Transcriptional Upregulation of the MDM4 Oncogene in HCC
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Author count: 9
Polaczek R., Schürmann P., Speith L.M., Geffers R., Dürst M., Hillemanns P., Park-Simon T.W., ... , Liebrich C., Dörk T.
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Germline variation of Ribonuclease H2 genes in ovarian cancer patients
J.Ovarian Res.,
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Author count: 14
Kopejtka K., Tomasch J., Zeng Y., Selyanin V., Dachev M., Piwosz K., Tichy M., Bína D., Gardian Z., Bunk B., Brinkmann H., Geffers R., ... , Sommaruga R., Koblizek M.
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Simultaneous presence of bacteriochlorophyll and xanthorhodopsin genes in a freshwater bacterium
mSystems,
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Author count: 12
Mederacke Y.S., Nienen M., Jarek M., Geffers R., Hupa-Breier K., Babel N., Reinke P., Mederacke I., Rudolf Vondran F.W., Jonigk D., ... , Wedemeyer H., Jaeckel E.
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T cell receptor repertoires within liver allografts are different to those in the peripheral blood
J.Hepatol.,
74
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Author count: 12
Ebert K., Zwingenberger G., Barbaria E., Keller S., Heck C., Arnold R., Hollerieth V., Mattes J., Geffers R., Raimúndez E., ... , Hasenauer J., Luber B.
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Correction to: Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines (BMC Cancer, (2020), 20, 1, (1039), 10.1186/s12885-020-07540-7)
BMC Cancer,
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Author count: 18
Schimmel K., Stojanovic S.D., Huang C.K., Jung M., Meyer M.H., Xiao K., Grote-Levi L., Bär C., Pfanne A., Mitzka S., Just A., Geffers R., Bock K., Kenneweg F., Kleemiß F., Falk C.S., ... , Fiedler J., Thum T.
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Combined high-throughput library screening and next generation RNA sequencing uncover microRNAs controlling human cardiac fibroblast biology
J.Mol.Cell.Cardiol.,
150
Author count: 12
Ebert K., Zwingenberger G., Barbaria E., Keller S., Heck C., Arnold R., Hollerieth V., Mattes J., Geffers R., Raimúndez E., ... , Hasenauer J., Luber B.
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Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines
BMC.Cancer,
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Author count: 8
Singh A.K., Rooge S.B., Varshney A., Vasudevan M., Kumar M., Geffers R., ... , Kumar V., Sarin S.K.
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Identification of miRNAs associated with dendritic cell dysfunction during acute and chronic hepatitis B virus infection
J.Med.Virol.,
93
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Author count: 9
Pinel-Cabello M., Jroundi F., López-Fernández M., Geffers R., Jarek M., Jauregui R., Link A., ... , Vilchez-Vargas R., Merroun M.L.
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Multisystem combined uranium resistance mechanisms and bioremediation potential of Stenotrophomonas bentonitica BII-R7: Transcriptomics and microscopic study
J.Hazard.Mater.,
403
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Hessman C.L., Hildebrandt J., Shah A., Brandt S., Bock A., Frye B.C., Raffetseder U., Geffers R., Brunner-Weinzierl M.C., Isermann B., ... , Mertens P.R., Lindquist J.A.
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YB-1 Interferes with TNFa[alpha]-TNFR Binding and Modulates Progranulin-Mediated Inhibition of TNFa[alpha] Signaling
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Kattih B., Shirvani A., Klement P., Garrido A.M., Gabdoulline R., Liebich A., Brandes M., Chaturvedi A., Seeger T., Thol F., Göhring G., Schlegelberger B., Geffers R., John D., Bavendiek U., Bauersachs J., Ganser A., ... , Heineke J., Heuser M.
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IDH1/2 mutations in acute myeloid leukemia patients and risk of coronary artery disease and cardiac dysfunction-a retrospective propensity score analysis
Leukemia
Author count: 133
Schulte-Schrepping J., Reusch N., Paclik D., Baßler K., Schlickeiser S., Zhang B., Krämer B., Krammer T., Brumhard S., Bonaguro L., De Domenico E., Wendisch D., Grasshoff M., Kapellos T.S., Beckstette M., Pecht T., Saglam A., Dietrich O., Mei H.E., Schulz A.R., Conrad C., Kunkel D., Vafadarnejad E., Xu C.J., Horne A., Herbert M., Drews A., Thibeault C., Pfeiffer M., Hippenstiel S., Hocke A., Müller-Redetzky H., Heim K.M., Machleidt F., Uhrig A., Bosquillon de Jarcy L., Jürgens L., Stegemann M., Glösenkamp C.R., Volk H.D., Goffinet C., Landthaler M., Wyler E., Georg P., Schneider M., Dang-Heine C., Neuwinger N., Kappert K., Tauber R., Corman V., Raabe J., Kaiser K.M., Vinh M.T., Rieke G., Meisel C., Ulas T., Becker M., Geffers R., Witzenrath M., Drosten C., Suttorp N., von Kalle C., Kurth F., Händler K., Schultze J.L., Aschenbrenner A.C., Li Y., Nattermann J., Sawitzki B., Saliba A.E., Sander L.E., Angelov A., Bals R., Bartholomäus A., Becker A., Bezdan D., Bonifacio E., Bork P., Clavel T., Colome-Tatche M., Diefenbach A., Dilthey A., Fischer N., Förstner K., Frick J.S., Gagneur J., Goesmann A., Hain T., Hummel M., Janssen S., Kalinowski J., Kallies R., Kehr B., Keller A., Kim-Hellmuth S., Klein C., Kohlbacher O., Korbel J.O., Kurth I., Ludwig K., Makarewicz O., Marz M., McHardy A., Mertes C., Nöthen M., Nürnberg P., Ohler U., Ossowski S., Overmann J., Peter S., Pfeffer K., Poetsch A.R., Pühler A., Rajewsky N., Ralser M., Rieß O., Ripke S., Nunes da Rocha U., Rosenstiel P., Schiffer P., Schulte E.C., Sczyrba A., Stegle O., Stoye J., Theis F., Vehreschild J., Vogel J., von Kleist M., Walker A., Walter J., Wieczorek D., ... , Ziebuhr J., Deutsche C.O.V.I.
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Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment
Cell,
182
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Author count: 19
Brandt S., Ballhause T.M., Bernhardt A., Becker A., Salaru D., Le-Deffge H.M., Fehr A., Fu Y., Philipsen L., Djudjaj S., Müller A.J., Kramann R., Ibrahim M., Geffers R., Siebel C., Isermann B., Heidel F.H., ... , Lindquist J.A., Mertens P.R.
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Fibrosis and Immune Cell Infiltration Are Separate Events Regulated by Cell-Specific Receptor Notch3 Expression
J.Am.Soc.Nephrol.,
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Author count: 11
Becker C.G., Bletz M.C., Greenspan S.E., Rodriguez D., Lambertini C., Jenkinson T.S., Assis A.P.A., Geffers R., Jarek M., ... , Toledo L.F., Vences M.
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Low-load pathogen spillover predicts shifts in skin microbiome and survival of a terrestrial-breeding amphibian
Proc.R.Soc.B Biol.Sci.,
286
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Author count: 17
Martens H., Hennies I., Getwan M., Christians A., Weiss A.C., Brand F., Gjerstad A.C., Christians A., Gucev Z., Geffers R., Seeman T., Kispert A., Tasic V., Bjerre A., Lienkamp S.S., ... , Haffner D., Weber R.G.
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Rare heterozygous GDF6 variants in patients with renal anomalies
Eur.J.Hum.Genet.,
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Author count: 14
Fuchs M., Kreutzer F.P., Kapsner L.A., Mitzka S., Just A., Perbellini F., Terracciano C.M., Xiao K., Geffers R., Bogdan C., Prokosch H.U., Fiedler J., ... , Thum T., Kunz M.
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Integrative bioinformatic analyses of global transcriptome data decipher novel molecular insights into cardiac anti-fibrotic therapies
Int.J.Mol.Sci.,
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Author count: 16
Goeser F., Münch P., Lesker T.R., Lutz P.L., Krämer B., Kaczmarek D.J., Finnemann C., Nischalke H.D., Geffers R., Parcina M., McHardy A., Strassburg C., Hoerauf A., Nattermann J., ... , Bekeredjian-Ding I., Spengler U.
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Neither black nor white: Do altered intestinal microbiota reflect chronic liver disease severity?
GUT,
70
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Author count: 4
Kar S., Geffers R., Samii A., Bertalanffy H.
(2020)
Library Preparation for Small RNA Transcriptome Sequencing in Patients Affected by Cerebral Cavernous Malformations
Methods Mol.Biol.
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Author count: 18
Chaturvedi A., Gupta C., Gabdoulline R., Borchert N.M., Goparaju R., Kaulfuss S., Görlich K., Schottmann R., Othman B., Welzenbach J., Panknin O., Wagner M., Geffers R., Ganser A., Thol F., Jeffers M., ... , Haegebarth A., Heuser M.
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Synergistic activity of IDH1 inhibitor BAY1436032 with azacitidine in IDH1 mutant acute myeloid leukemia
Haematologica,
106
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Author count: 45
Schimmel K., Jung M., Foinquinos A., San Jose G., Beaumont J., Bock K., Grote-Levi L., Xiao K., Bär C., Pfanne A., Just A., Zimmer K., Ngoy S., Lopez B., Ravassa S., Samolovac S., Janssen-Peters H., Remke J., Scherf K., Dangwal S., Piccoli M.T., Kleemiss F., Kreutzer F.P., Kenneweg F., Leonardy J., Hobuss L., Santer L., Do Q.T., Geffers R., Braesen J.H., Schmitz J., Brandenberger C., Müller D.N., Wilck N., Kaever V., Bähre H., Batkai S., Fiedler J., Alexander K.M., Wertheim B.M., Fisch S., Liao R., Diez J., ... , Gonzalez A., Thum T.
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Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction
Circulation,
141
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Author count: 21
Matos A.D.R., Wunderlich K., Schloer S., Schughart K., Geffers R., Seders M., Witt M.D., Christersson A., Wiewrodt R., Wiebe K., Barth P., Hocke A., Hippenstiel S., Hönzke K., Dittmer U., Sutter K., Rescher U., Rodionycheva S., Matera N., ... , Ludwig S., Brunotte L.
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Antiviral potential of human IFN-a[alpha] subtypes against influenza A H3N2 infection in human lung explants reveals subtype-specific activities
Emerg.Microbes Infect.,
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Author count: 14
Maluski M., Ghosh A., Herbst J., Scholl V., Baumann R., Hühn J., Geffers R., Meyer J., Maul H., Eiz-Vesper B., Krueger A., Schambach A., ... , van den Brink M.R.M., Sauer M.G.
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Chimeric antigen receptor-induced BCL11B suppression propagates NK-like cell development
J.Clin.Invest.,
129
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Winkler I., Bitter C., Winkler S., Weichenhan D., Thavamani A., Hengstler J.G., Borkham-Kamphorst E., Kohlbacher O., Plass C., Geffers R., ... , Weiskirchen R., Nordheim A.
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Identification of Ppargamma-modulated miRNA hubs that target the fibrotic tumor microenvironment
Proc.Natl.Acad.Sci.U.S.A,
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Author count: 12
de Araujo L.S., Ribeiro-Alves M., Leal-Calvo T., Leung J., Duran V., Samir M., Talbot S., Tallam A., Mello F.C.Q., Geffers R., ... , Saad M.H.F., Pessler F.
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Reprogramming of Small Noncoding RNA Populations in Peripheral Blood Reveals Host Biomarkers for Latent and Active Mycobacterium tuberculosis Infection
MBio.,
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Author count: 11
Waindok P., Janecek-Erfurth E., Lindenwald D., Wilk E., Schughart K., Geffers R., Balas L., Durand T., Rund K.M., ... , Schebb N.H., Strube C.
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Multiplex profiling of inflammation-related bioactive lipid mediators in Toxocara canis- and Toxocara cati-induced neurotoxocarosis
PLoS Negl.Trop.Dis.,
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Author count: 10
Samir M., Vidal R.O., Abdallah F., Capece V., Seehusen F., Geffers R., Hussein A., Ali A.A.H., ... , Bonn S., Pessler F.
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Organ-specific small non-coding RNA responses in domestic (Sudani) ducks experimentally infected with highly pathogenic avian influenza virus (H5N1)
RNA.Biol.,
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Author count: 16
Scharf G.M., Kilian K., Cordero J., Wang Y., Grund A., Hofmann M., Froese N., Wang X., Kispert A., Kist R., Conway S.J., Geffers R., Wollert K.C., Dobreva G., ... , Bauersachs J., Heineke J.
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Inactivation of Sox9 in fibroblasts reduces cardiac fibrosis and inflammation
JCI Insight,
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Author count: 25
Tang B.M., Shojaei M., Teoh S., Meyers A., Ho J., Ball T.B., Keynan Y., Pisipati A., Kumar A., Eisen D.P., Lai K., Gillett M., Santram R., Geffers R., Schreiber J., Mozhui K., Huang S., Parnell G.P., Nalos M., Holubova M., Chew T., Booth D., Kumar A., ... , McLean A., Schughart K.
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Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection
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Sogkas G., Dubrowinskaja N., Bergmann A.K., Lentes J., Ripperger T., Fedchenko M., Ernst D., Jablonka A., Geffers R., Baumann U., ... , Schmidt R.E., Atschekzei F.
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Progressive Immunodeficiency with Gradual Depletion of B and CD4(+) T Cells in Immunodeficiency, Centromeric Instability and Facial Anomalies Syndrome 2 (ICF2)
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Author count: 4
Olsen R.S., Dimberg J., Geffers R., Wagsäter D.
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Possible Role and Therapeutic Target of PDGF-D Signalling in Colorectal Cancer
Cancer Invest.,
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Author count: 9
Sonnenschein K., Fiedler J., Pfanne A., Just A., Mitzka S., Geffers R.R., Pich A., ... , Bauersachs J., Thum T.
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Therapeutic modulation of RNA-binding protein Rbm38 facilitates re-endothelialization after arterial injury
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Author count: 42
Kueneman J.G., Bletz M.C., McKenzie V.J., Becker C.G., Joseph M.B., Abarca J.G., Archer H., Arellano A.L., Bataille A., Becker M., Belden L.K., Crottini A., Geffers R., Haddad C.F.B., Harris R.N., Holden W.M., Hughey M., Jarek M., Kearns P.J., Kerby J.L., Kielgast J., Kurabayashi A., Longo A.V., Loudon A., Medina D., Nunez J.J., Perl R.G.B., Pinto-Tomas A., Rabemananjara F.C.E., Rebollar E.A., Rodriguez A., Rollins-Smith L., Stevenson R., Tebbe C.C., Vargas Asensio G., Waldman B., Walke J.B., Whitfield S.M., Zamudio K.R., Zuniga Chaves I., ... , Woodhams D.C., Vences M.
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Community richness of amphibian skin bacteria correlates with bioclimate at the global scale
Nat.Ecol.Evol.,
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Guo Y., Cichocki N., Schattenberg F., Geffers R., Harms H., Müller S.
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AgNPs Change Microbial Community Structures of Wastewater
Front Microbiol.,
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Seifert O., Matussek A., Sjögren F., Geffers R., Anderson C.D.
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Gene expression profiling of macrophages: Implications for an immunosuppressive effect of dissolucytotic gold ions
Journal of Inflammation,
9
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Froese N., Wang H., Zwadlo C., Wang Y., Grund A., Gigina A., Hofmann M., Kilian K., Scharf G., Korf-Klingebiel M., Melchert A., Signorini M.E.R., Halloin C., Zweigerdt R., Martin U., Gruh I., Wollert K.C., Geffers R., ... , Bauersachs J., Heineke J.
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Corrigendum to "Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice" [Journal of Molecular and Cellular Cardiology 122 (2018) 114-124]
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125
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Author count: 10
Guo L., Huang J., Chen M., Piotrowski E., Song N., Zahner G., Paust H.J., Alawi M., ... , Geffers R., Thaiss F.
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T-lymphocyte-specific knockout of IKK-2 or NEMO induces Th17 cells in an experimental nephrotoxic nephritis mouse model
FASEB J.,
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Jeron A., Boehme J.D., Volckmar J., Gereke M., Yevsa T., Geffers R., Guzmán C.A., Schreiber J., ... , Stegemann-Koniszewski S., Bruder D.
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Respiratory bordetella bronchiseptica carriage is associated with broad phenotypic alterations of peripheral CD4+CD25+ T cells and differentially affects immune responses to secondary non-infectious and infectious stimuli in mice
Int.J.Mol.Sci.,
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Author count: 6
Kollmus H., Pilzner C., Leist S.R., Heise M., Geffers R., Schughart K.
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Of mice and men: the host response to influenza virus infection
Mamm.Genome,
29
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Froese N., Wang H., Zwadlo C., Wang Y., Grund A., Gigina A., Hofmann M., Kilian K., Scharf G., Korf-Klingebiel M., Melchert A., Signorini M.E.R., Halloin C., Zweigerdt R., Martin U., Gruh I., Wollert K.C., Geffers R., ... , Bauersachs J., Heineke J.
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Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice
J.Mol.Cell.Cardiol.,
122
(Sept)
Author count: 17
Ravens S., Schultze-Florey C., Raha S., Sandrock I., Drenker M., Oberd÷rfer L., Reinhardt A., Ravens I., Beck M., Geffers R., Von Kaisenberg C., Heuser M., Thol F., Ganser A., Förster R., ... , Koenecke C., Prinz I.
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Erratum to: Human gamma delta T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection (Nature Immunology, (2017), 18, 4, (393-401), 10.1038/ni.3686)
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Koestner W., Spanier J., Klause T., Tegtmeyer P.K., Becker J., Herder V., Borst K., Todt D., Lienenklaus S., Gerhauser I., Detje C.N., Geffers R., Langereis M.A., Vondran F.W.R., Yuan Q., van Kuppeveld F.J.M., Ott M., Staeheli P., Steinmann E., Baumgärtner W., ... , Wacker F., Kalinke U.
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Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice
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Author count: 10
Kremling A., Goehler A., Jahreis K., Nees M., Auerbach B., Schmidt-Heck W., Kökpinar Í., Geffers R., ... , Rinas U., Bettenbrock K.
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Analysis and design of stimulus response curves of E. coli
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Hosseini S., Wilk E., Michaelsen-Preusse K., Gerhauser I., Baumgärtner W., Geffers R., ... , Schughart K., Korte M.
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Long-term neuroinflammation induced by influenza A virus infection and the impact on hippocampal neuron morphology and function
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Tomasch J., Wang H., Hall A.T.K., Patzelt D., Preusse M., Petersen J., Brinkmann H., Bunk B., Bhuju S., Jarek M., Geffers R., ... , Lang A.S., Wagner-Döbler I.
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Packaging of Dinoroseobacter shibae DNA into Gene Transfer Agent Particles Is Not Random
Genome Biol.Evol.,
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Author count: 8
Riahi A., Radmanesh H., Schürmann P., Bogdanova N., Geffers R., Meddeb R., ... , Kharrat M., Dörk T.
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Exome sequencing and case-control analyses identify RCC1 as a candidate breast cancer susceptibility gene
Int.J.Cancer,
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Author count: 9
Glaesener S., Jaenke C., Habener A., Geffers R., Hagendorff P., Witzlau K., Imelmann E., ... , Krueger A., Meyer-Bahlburg A.
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Decreased production of class-switched antibodies in neonatal B cells is associated with increased expression of miR-181b
PLoS.ONE.,
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Author count: 8
Walter C., Pozzorini C., Reinhardt K., Geffers R., Xu Z., Reinhardt D., ... , von Neuhoff N., Hanenberg H.
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Single-cell whole exome and targeted sequencing in NPM1/FLT3 positive pediatric acute myeloid leukemia
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Pietrucha B., Heropolitanska-Pliszka E., Geffers R., Enßen J., Wieland B., ... , Bogdanova N.V., Dörk T.
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Clinical and biological manifestation of RNF168 deficiency in two polish siblings
Front.Immunol.,
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Wang J., Bogdanova N., Schürmann P., Park-Simon T.W., Geffers R., Dörk T.
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Assessment of a FBXW8 frameshift mutation, c.1312_1313delGT, in breast cancer patients and controls from Central Europe
Cancer Genet.,
220
(January)
Author count: 11
Singh A.K., Rooge S.B., Varshney A., Vasudevan M., Bhardwaj A., Venugopal S.K., TrehanPati N., Kumar M., Geffers R., ... , Kumar V., Sarin S.K.
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Global micro RNA expression profiling in the liver biopsies of Hepatitis B Virus infected patients suggests specific miRNA signatures for viral persistence and hepatocellular injury
Hepatology,
67
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Author count: 13
Chen S., Nagel S., Schneider B., Dai H., Geffers R., Kaufmann M., Meyer C., Pommerenke C., Thress K.S., Li J., Quentmeier H., ... , Drexler H.G., MacLeod R.A.F.
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A new ETV6-NTRK3 cell line model reveals MALAT1 as a novel therapeutic target - a short report
Cell Oncol.(Dordr.)
Author count: 5
Schneefeld M., Busche T., Geffers R., Kalinowski J., Bange F.C.
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The transcriptional regulator LysG (Rv1985c) of Mycobacterium tuberculosis activates lysE (Rv1986) in a lysine-dependent manner
PLoS.ONE.,
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Author count: 17
Chaturvedi A., raujo Cruz M.M., Jyotsana N., Sharma A., Goparaju R., Schwarzer A., Gorlich K., Schottmann R., Struys E.A., Jansen E.E., Rohde C., Muller-Tidow C., Geffers R., Gohring G., Ganser A., ... , Thol F., Heuser M.
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Enantiomer-specific and paracrine leukemogenicity of mutant IDH metabolite 2-hydroxyglutarate
Leukemia,
30
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Author count: 29
Chaturvedi A., Herbst L., Pusch S., Klett L., Goparaju R., Stichel D., Kaulfuss S., Panknin O., Zimmermann K., Toschi L., Neuhaus R., Haegebarth A., Rehwinkel H., Hess-Stumpp H., Bauser M., Bochtler T., Struys E.A., Sharma A., Bakkali A., Geffers R., raujo-Cruz M.M., Thol F., Gabdoulline R., Ganser A., Ho A.D., von Deimling A., Rippe K., ... , Heuser M., Kramer A.
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Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo
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Nikolouli E., Hardtke-Wolenski M., Hapke M., Beckstette M., Geffers R., Floess S., ... , Jaeckel E., Hühn J.
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Alloantigen-induced regulatory t cells generated in presence of vitamin c display enhanced stability of foxp3 expression and promote skin allograft acceptance
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Ehrentraut S., Nagel S., Pommerenke C., Dirks W.G., Quentmeier H., Kaufmann M., Meyer C., Zaborski M., Geffers R., Fujiwara H., ... , Drexler H.G., MacLeod R.A.F.
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Peripheral T-cell lymphoma cell line T8ML-1 highlights conspicuous targeting of PVRL2 by t(14;19)(q11.2;q13.3)
Haematologica,
102
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Author count: 17
Ravens S., Schultze-Florey C., Raha S., Sandrock I., Drenker M., Oberdorfer L., Reinhardt A., Ravens I., Beck M., Geffers R., von Kaisenberg C., Heuser M., Thol F., Ganser A., Forster R., ... , Koenecke C., Prinz I.
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Human gammadelta T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection
Nat.Immunol.,
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Westendorf A.M., Skibbe K., Adamczyk A., Buer J., Geffers R., Hansen W., ... , Pastille E., Jendrossek V.
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Hypoxia Enhances Immunosuppression by Inhibiting CD4+ Effector T Cell Function and Promoting Treg Activity
Cell Physiol Biochem.,
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Author count: 17
Bernhardt A., Fehr A., Brandt S., Jerchel S., Ballhause T.M., Philipsen L., Stolze S., Geffers R., Weng H., Fischer K.D., Isermann B., Brunner-Weinzierl M.C., Batra A., Siegmund B., Zhu C., ... , Lindquist J.A., Mertens P.R.
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Inflammatory cell infiltration and resolution of kidney inflammation is orchestrated by the cold-shock protein Y-box binding protein-1
Kidney Int.,
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Heuser M., Gabdoulline R., Loffeld P., Dobbernack V., Kreimeyer H., Pankratz M., Flintrop M., Liebich A., Klesse S., Panagiota V., Stadler M., Wichmann M., Shahswar R., Platzbecker U., Thiede C., Schroeder T., Kobbe G., Geffers R., Schlegelberger B., Gohring G., Kreipe H.H., Germing U., Ganser A., Kroger N., ... , Koenecke C., Thol F.
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Individual outcome prediction for myelodysplastic syndrome (MDS) and secondary acute myeloid leukemia from MDS after allogeneic hematopoietic cell transplantation
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Tang B.M., Shojaei M., Parnell G.P., Huang S., Nalos M., Teoh S., O'Connor K., Schibeci S., Phu A.L., Kumar A., Ho J., Meyers A.F.A., Keynan Y., Ball T., Pisipati A., Kumar A., Moore E., Eisen D., Lai K., Gillett M., Geffers R., Luo H., Gul F., Schreiber J., Riedel S., Booth D., ... , McLean A., Schughart K.
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A novel immune biomarker IFI27 discriminates between influenza and bacteria in patients with suspected respiratory infection
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Kleist S., Ulbrich M., Bill N., Schmidt-Hohagen K., Geffers R., Schomburg D.
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Dealing with salinity extremes and nitrogen limitation - an unexpected strategy of the marine bacterium Dinoroseobacter shibae
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Cutaneous Bacterial Communities of a Poisonous Salamander: a Perspective from Life Stages, Body Parts and Environmental Conditions
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Temporal changes in cutaneous bacterial communities of terrestrial- and aquatic- phase newts (Amphibia)
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Atschekzei F., Dörk T., Schürmann P., Geffers R., Witte T., Schmidt R.E.
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Limited role of interferon-kappa (IFNK) truncating mutations in common variable immunodeficiency
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Kar S., Bali K.K., Baisantry A., Geffers R., Samii A., Bertalanffy H.
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Genome-Wide Sequencing Reveals MicroRNAs Downregulated in Cerebral Cavernous Malformations
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Assessment of an APOBEC3B truncating mutation, c.783delG, in patients with breast cancer
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Tracking HCV protease population diversity during transmission and susceptibility of founder populations to antiviral therapy
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139
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Noyan F., Zimmermann K., Hardtke-Wolenski M., Knoefel A., Schulde E., Geffers R., Hust M., Hühn J., Galla M., Morgan M., Jokuszies A., ... , Manns M.P., Jaeckel E.
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Prevention of allograft rejection by use of regulatory T cells with a MHC-specific chimeric antigen receptor
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Amphibian gut microbiota shifts differentially in community structure but converges on habitat-specific predicted functions
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Deletion of Irf3 and Irf7 Genes in Mice Results in Altered Interferon Pathway Activation and Granulocyte-Dominated Inflammatory Responses to Influenza A Infection
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Transcriptomic Biomarkers for Tuberculosis: Evaluation of DOCK9. EPHA4, and NPC2 mRNA Expression in Peripheral Blood
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Imatinib reduces cholesterol uptake and matrix metalloproteinase activity in human THP-1 macrophages
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Freshwater vertebrate metabarcoding on Illumina platforms using double-indexed primers of the mitochondrial 16S rRNA gene
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IL-10 downregulates CXCR3 expression on Th1 cells and interferes with their migration to intestinal inflammatory sites
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Draft Genome Sequence of Aeromonas sp. Strain EERV15
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Dual Role of the Adaptive Immune System in Liver Injury and Hepatocellular Carcinoma Development
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Enhanced whole exome sequencing by higher DNA insert lengths
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Th17 cytokine differentiation and loss of plasticity after SOCS1 inactivation in a cutaneous T-cell lymphoma
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McMillan D.J., Geffers R., Schouls L.M., Vlaminckx B.J.M., Sriprakash K.S., ... , Wannet W., Chhatwal G.S.
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Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice
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Lima-Morales D., Jauregui R., Camarinha-Silva A., Geffers R., Pieper D.H., Vilchez-Vargas R.
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Overexpression of CD45RA isoforms in carriers of the C77G mutation leads to hyporeactivity of CD4+CD25highFoxp3+ regulatory T cells
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First Draft Genome Sequence of the Acidovorax caeni sp. nov. Type Strain R-24608 (DSM 19327)
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Development of Long Noncoding RNA-Based Strategies to Modulate Tissue Vascularization
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Targeting a host-cell entry factor barricades antiviral-resistant HCV variants from on-therapy breakthrough in human-liver mice
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Genomic Analysis and Isolation of RNA Polymerase II Dependent Promoters from Spodoptera frugiperda
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Hueging K., Weller R., Doepke M., Vieyres G., Todt D., Wolk B., Vondran F.W., Geffers R., Lauber C., Kaderali L., ... , Penin F., Pietschmann T.
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Several Human Liver Cell Expressed Apolipoproteins Complement HCV Virus Production with Varying Efficacy Conferring Differential Specific Infectivity to Released Viruses
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Lauber C., Vieyres G., Terczynska-Dyla E., Anggakusuma, Dijkman R., Gad H.H., Akhtar H., Geffers R., Vondran F.W., Thiel V., Kaderali L., ... , Pietschmann T., Hartmann R.
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Transcriptome analysis reveals a classical interferon signature induced by IFNlambda4 in human primary cells
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Woller N., Gurlevik E., Fleischmann-Mundt B., Schumacher A., Knocke S., Kloos A.M., Saborowski M., Geffers R., Manns M.P., Wirth T.C., ... , Kubicka S., Kuhnel F.
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Viral infection of tumors overcomes resistance to PD-1-immunotherapy by broadening neoantigenome-directed T-cell responses
Mol.Ther.,
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Ding J., Dirks W.G., Ehrentraut S., Geffers R., MacLeod R.A., Nagel S., Pommerenke C., Romani J., Scherr M., Vaas L.A., Zaborski M., ... , Drexler H.G., Quentmeier H.
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BCL6 - Regulated by AhR/ARNT and wild-type MEF2B - Drives expression of germinal center markers MYBL1 and LMO2
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Ehsani E., Jauregui R., Geffers R., Jareck M., Boon N., ... , Pieper D.H., Vilchez-Vargas R.
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Draft Genome Sequence of Rhodococcus sp. Strain 311R
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The CpG island methylator phenotype in breast cancer is associated with the lobular subtype
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Orlik J., Schungel S., Buitrago-Molina L.E., Geffers R., Endig J., Marhenke S., Lobschat K., Rossler S., Goeppert B., Manns M.P., ... , Gross A., Vogel A.
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The BH3-only protein BID impairs the p38-mediated stress response and promotes hepatocarcinogenesis during chronic liver injury in mice
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Janik K., Bode J., Dutow P., Laudeley R., Geffers R., Sommer K., ... , Glage S., Klos A.
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Temperature and host cell-dependent changes in virulence of Chlamydia pneumoniae CWL029 in an optimized mouse infection model
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Janecek E., Wilk E., Schughart K., Geffers R., Strube C.
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Microarray gene expression analysis reveals major differences between Toxocara canis and Toxocara cati neurotoxocarosis and involvement of T. canis in lipid biosynthetic processes
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Ohrnberger S., Thavamani A., Braeuning A., Lipka D.B., Kirilov M., Geffers R., Authenrieth S.E., Römer M., Zell A., Bonin M., Schwarz M., Schütz G., Schirmacher P., Plass C., ... , Longerich T., Nordheim A.
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Dysregulated serum response factor triggers formation of hepatocellular carcinoma
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Segregation of a spontaneous Klrd1 (CD94) mutation in DBA/2 mouse substrains
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Strehmel J., Neidig A., Nusser M., Geffers Robert, Brenner-Weiss G., Overhage J.
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The sensor kinase PA4398 modulates swarming motility and biofilm formation in Pseudomonas aeruginosa PA14
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Elgohary N., Pellegrino R., Neumann O., Elzawahry H.M., Saber M.M., Zeeneldin A.A., Geffers Robert, Ehemann V., Schemmer P., ... , Schirmacher P., Longerich T.
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Protumorigenic role of Timeless in hepatocellular carcinoma
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Vazquez C.L., Lerner T.R., Kasmapour B., Pei G., Gronow Achim, Bianco M.V., Blanco F.C., Bleck C.K., Geffers Robert, Bigi F., ... , Abraham Wolf-Rainer, Gutierrez Maximiliano G.
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Experimental selection of long-term intracellular mycobacteria
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In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer
Nature medicine
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Winkler J., Ori A., Holzer K., Sticht C., Dauch D., Eiteneuer E.M., Pinna F., Geffers Robert, Ehemann V., Andres-Pons A., Breuhahn K., Longerich T., Bermejo J.L., Gretz N., Zender L., Schirmacher P., ... , Beck M., Singer S.
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Prosurvival function of the cellular apoptosis susceptibility/importin-?1 transport cycle is repressed by p53 in liver cancer
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Marhenke S., Buitrago-Molina L.E., Endig J., Orlik J., Schweitzer N., Klett S., Longerich T., Geffers Robert, Munoz A.S., Dorrell C., Katz S.F., Lechel A., Weng H., Krech T., Lehmann U., Dooley S., Rudolph K.L., ... , Manns M.P., Vogel A.
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P21 promotes sustained liver regeneration and hepatocarcinogenesis in chronic cholestatic liver injury
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Independent Bottlenecks Characterize Colonization of Systemic Compartments and Gut Lymphoid Tissue by Salmonella
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Kehrmann J., Tatura R., Zeschnigk M., Probst-Kepper Michael, Geffers Robert, ... , Steinmann J., Buer J.
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Yun H., Damm F., Yap D., Schwarzer A., Chaturvedi A., Jyotsana N., Lubbert M., Bullinger L., Dohner K., Geffers Robert, Aparicio S., Humphries R.K., ... , Ganser A., Heuser M.
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Impact of MLL5 expression on decitabine efficacy and DNA methylation in acute myeloid leukemia
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A replication study for genome-wide gene expression levels in two layer lines elucidates differentially expressed genes of pathways involved in bone remodeling and immune responsiveness
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Gutschner T., Hammerle M., Pazaitis N., Bley N., Fiskin E., Uckelmann H., Heim A., Grobeta M., Hofmann N., Geffers Robert, Skawran B., Longerich T., Breuhahn K., Schirmacher P., Muhleck B., ... , Huttelmaier S., Diederichs S.
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Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma
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Sagar V., Bergmann René, Nerlich A., McMillan D.J., Nitsche-Schmitz D.Patric, Fulde M., Talay Susanne, Geffers Robert, Hoe N., Kumar R., Rohde M., ... , Chakraborti A., Chhatwal Gursharan S.
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Jauregui Ruy, Rodelas B., Geffers Robert, Boon N., Pieper Dietmar H., Vilchez-Vargas Ramiro
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Draft Genome Sequence of the Naphthalene Degrader Herbaspirillum sp. Strain RV1423
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Dag F., Dolken L., Holzki J., Drabig A., Weingartner A., Schwerk J., Lienenklaus S., Conte I., Geffers R., Davenport C., Rand U., Köster M., Weiss S., Adler B., Wirth D., Messerle M., ... , Hauser H., Cicin-Sain L.
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Reversible silencing of cytomegalovirus genomes by type I interferon governs virus latency
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Human host defense peptide LL-37 Stimulates virulence factor production and adaptive resistance in Pseudomonas aeruginosa
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Hämmerle M., Gutschner T., Uckelmann H., Ozgur S., Fiskin E., Gross M., Skawran B., Geffers Robert, Longerich T., Breuhahn K., Schirmacher P., ... , Stoecklin G., Diederichs S.
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MicroRNA-Mediated Epigenetic Silencing of Sirtuin1 Contributes to Impaired Angiogenic Responses1
Circulation Research,
113
(8)
Author count: 9
Buitrago-Molina L.E., Marhenke S., Longerich T., Sharma A.D., Boukouris A.E., Geffers Robert, Guigas Bruno, ... , Manns M.P., Vogel A.
(2013)
The degree of liver injury determines the role of p21 in liver regeneration and hepatocarcinogenesis in mice
Hepatology,
58
(3)
Author count: 6
Hasemeier B., Geffers Robert, Bartels S., Schlegelberger B., Kreipe H., Lehmann U.
(2013)
Archival bone marrow trephines are suitable for high-throughput mutation analysis using next generation sequencing technology
Haematologica,
98
(9)
Author count: 6
Jeron A., Hansen W., Ewert F., Buer J., Geffers R., Bruder D.
(2012)
ChIP-on-chip analysis identifies IL-22 as direct target gene of ectopically expressed FOXP3 transcription factor in human T cells
BMC GENOMICS,
13
(1)
Author count: 15
Zender S., Nickeleit I., Wuestefeld T., Sörensen I., Dauch D., Bozko P., El-Khatib M., Geffers Robert, Bektas H., Manns M., Gossler A., Wilkens L., Plentz R., ... , Zender L., Malek N.
(2013)
A critical role for notch signaling in the formation of cholangiocellular carcinomas
Cancer Cell,
23
(6)
Author count: 8
Shepelkova G., Pommerenke C., Alberts R., Geffers Robert, Evstifeev V., Apt A., ... , Schughart Klaus, Wilk E.
(2013)
Analysis of the lung transcriptome in Mycobacterium tuberculosis-infected mice reveals major differences in immune response pathways between TB-susceptible and resistant hosts
Tuberculosis (Edinb.),
93
(2)
Author count: 15
Sundarasetty B.S., Singh V.K., Salguero G., Geffers Robert, Rickmann M., Macke L., Borchers S., Figueiredo C., Schambach A., Gullberg U., Provasi E., Bonini C., Ganser A., ... , Woelfel T., Stripecke R.
(2013)
Lentivirus-induced dendritic cells for immunization against high-risk WT1(+) acute myeloid leukemia
Human gene therapy,
24
(2)
Author count: 12
Quentmeier H., Amini R.M., Berglund M., Dirks W.G., Ehrentraut S., Geffers Robert, MacLeod R.A., Nagel S., Romani J., Scherr M., ... , Zaborski M., Drexler H.G.
(2013)
U-2932: two clones in one cell line, a tool for the study of clonal evolution
Leukemia,
27
(5)
Author count: 9
Vilchez-Vargas Ramiro, Geffers Robert, Suarez-Diez Maria, Conte Ianina, Waliczek Agnes, Kaser Vanessa S., Kralova M., ... , Junca H., Pieper Dietmar H.
(2013)
Analysis of the microbial gene landscape and transcriptome for aromatic pollutants and alkane degradation using a novel internally calibrated microarray system
Environmental Microbiology,
15
(4)
Author count: 18
Toker A., Engelbert D., Garg G., Polansky J.K., Floess S., Miyao T., Baron U., Düber S., Geffers R., Giehr P., Schallenberg S., Kretschmer K., Olek S., Walter J., Weiss S., Hori S., ... , Hamann A., Hühn J.
(2013)
Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus
Journal of Immunology,
190
(7)
Author count: 23
Wuestefeld T., Pesic M., Rudalska R., Dauch D., Longerich T., Kang T.W., Yevsa T., Heinzmann F., Hoenicke L., Hohmeyer A., Potapova A., Rittelmeier I., Jarek Michael, Geffers Robert, Scharfe Maren, Klawonn Frank, Schirmacher P., Malek N.P., Ott M., Nordheim A., Vogel A., ... , Manns M.P., Zender L.
(2013)
A direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration
Cell,
153
(2)
Author count: 12
Kindler E., Jonsdottir H.R., Muth D., Hamming O.J., Hartmann R., Rodriguez R., Geffers Robert., Fouchier R.A., Drosten C., Muller M.A., ... , Dijkman R., Thiel V.
(2013)
Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential
MBio,
4
(1)
Author count: 15
Ehrentraut S., Nagel S., Scherr M.E., Schneider B., Quentmeier H., Geffers Robert, Kaufmann M., Meyer C., Prochorec-Sobieszek M., Ketterling R.P., Knudson R.A., Feldman A.L., Kadin M.E., ... , Drexler H.G., MacLeod R.A.
(2013)
t(8;9)(p22;p24)/PCM1-JAK2 Activates SOCS2 and SOCS3 via STAT5
PLoS ONE,
8
(1)
Author count: 9
He F., Chen H., Probst-Kepper M., Geffers R., Eifes S., Del Sol A., Schughart K., ... , Zeng A.P., Balling R.
(2012)
PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells
Molecular Systems Biology,
8
Author count: 5
Ukena S.N., Geffers Robert, Buchholz S., Stadler M., Franzke A.
(2012)
Biomarkers for acute and chronic graft-versus-host disease in regulatory T cells
Transplant Immunology,
27
(4)
Author count: 8
Christgen M., Noskowicz M., Heil C., Schipper E., Christgen H., Geffers Robert, ... , Kreipe H., Lehmann U.
(2012)
IPH-926 lobular breast cancer cells harbor a p53 mutant with temperature-sensitive functional activity and allow for profiling of p53-responsive genes
Laboratory Investigation,
92
(11)
Author count: 10
Hamisch D., Randewig D., Schliesky S., Brautigam A., Weber A.P., Geffers Robert, Herschbach C., Rennenberg H., ... , Mendel R.R., Hansch R.
(2012)
Impact of SO(2) on Arabidopsis thaliana transcriptome in wildtype and sulfite oxidase knockout plants analyzed by RNA deep sequencing
New Phytologist,
196
(4)
Author count: 11
Neumann O., Kesselmeier M., Geffers Robert, Pellegrino R., Radlwimmer B., Hoffmann K., Ehemann V., Schemmer P., Schirmacher P., ... , Lorenzo Bermejo J., Longerich T.
(2012)
Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors
Hepatology,
56
(5)
Author count: 3
Habig C., Geffers Robert, Distl O.
(2012)
Differential gene expression from genome-wide microarray analyses distinguishes lohmann selected leghorn and lohmann brown layers
PLoS ONE,
7
(10)
Author count: 7
Pommerenke C., Wilk E., Srivastava B., Schulze A., Novoselova N., ... , Geffers Robert, Schughart Klaus
(2012)
Global transcriptome analysis in influenza-infected mouse lungs reveals the kinetics of innate and adaptive host immune responses
PLoS ONE,
7
(7)
Author count: 10
Nagel S., Ehrentraut S., Tomasch J., Lienenklaus S., Schneider B., Geffers Robert, Meyer C., Kaufmann M., ... , Drexler H.G., MacLeod R.A.
(2012)
Transcriptional Activation of Prostate Specific Homeobox Gene NKX3-1 in Subsets of T-Cell Lymphoblastic Leukemia (T-ALL)
PLoS ONE,
7
(7)
Author count: 10
Abel S., Luckheide N., Westendorf A.M., Geffers R., Roers A., Müller W., Sparwasser Tim*, Matuschewski K., ... , Buer J., Hansen W.
(2012)
Strong Impact of CD4+Foxp3+ Regulatory T Cells and Limited Effect of T Cell-Derived IL-10 on Pathogen Clearance during Plasmodium yoelii Infection
Journal of Immunology,
188
(11)
Author count: 14
Block J., Breitsprecher D., Kuhn S., Winterhoff M., Kage F., Geffers R., Duwe P., Rohn J.L., Baum B., Brakebusch C., Geyer M., Stradal T.E., ... , Faix J., Rottner K.
(2012)
FMNL2 Drives Actin-Based Protrusion and Migration Downstream of Cdc42
Current biology,
22
(11)
Author count: 9
Bendrat K., Stang A., Georgiev G., Geffers Robert, Haase B., Schutze K., Mogilarov D., ... , Branscheid D., Niendorf A.
(2012)
A compartment-specific transcriptome analysis reveals survival-relevant marker genes in the stroma fraction of squamous non-small cell lung cancer
Journal of Biophotonics,
5
(4)
Author count: 9
Alberts R., Chen H., Pommerenke C., Smit A.B., Spijker S., Williams R.W., Geffers Robert*, ... , Bruder Dunja*, Schughart Klaus*
(2011)
Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune disease1
BMC GENOMICS,
12
Author count: 8
Dötsch A., Eckweiler D., Schniederjans M., Zimmermann A., Jensen V., Scharfe M., ... , Geffers Robert, Häußler Susanne
(2012)
The Pseudomonas aeruginosa
PLoS ONE,
7
(2)
Author count: 9
Gohler A.K., Kokpinar O., Schmidt-Heck W., Geffers R., Guthke R., Rinas U., Schuster S., ... , Jahreis K., Kaleta C.
(2011)
More than just a metabolic regulator - elucidation and validation of new targets of PdhR in Escherichia coli1
BMC Systems Biology,
5
Author count: 4
Boppana S., Scheglov A., Geffers Robert, Tarabykin V.
(2012)
Cellular retinaldehyde-binding protein (CRALBP) is a direct downstream target of transcription factor Pax6
Biochimica et biophysica acta,
1820
(2)
Author count: 8
Schneider B., Nagel S., Ehrentraut S., Kaufmann M., Meyer C., Geffers Robert, ... , Drexler H.G., MacLeod R.A.
(2012)
Neoplastic MiR-17 approximately 92 deregulation at a dna fragility motif (SIDD)
Genes, Chromosomes and Cancer,
51
(3)
Author count: 6
Krech T., Scheuerer E., Geffers Robert, Kreipe H., Lehmann U., Christgen M.
(2012)
ABCB1/MDR1 contributes to the anticancer drug-resistant phenotype of IPH-926 human lobular breast cancer cells
Cancer Letters,
315
(2)
Author count: 6
Ziegler C., Goldmann O., Hobeika E., Geffers Robert*, Peters G., Medina Eva*
(2011)
The dynamics of T cells during persistent Staphylococcus aureus infection: from antigen-reactivity to in vivo anergy
EMBO Molecular Medicine,
3
(11)
Author count: 6
Svensson J., Jenmalm M.C., Matussek A., Geffers Robert*, Berg G., Ernerudh J.
(2011)
Macrophages at the fetal-maternal interface express markers of alternative activation and are induced by M-CSF and IL-10
Journal of Immunology,
187
(7)
Author count: 10
Ukena S.N., Velaga S., Geffers Robert*, Grosse J., Baron U., Buchholz S., Stadler M., Bruder Dunja*, ... , Ganser A., Franzke A.
(2011)
Human regulatory T cells in allogeneic stem cell transplantation
Blood,
118
(13)
Author count: 8
TrehanPati N., Sukriti S., Geffers R., Hissar S., Riese P., Toepfer T., ... , Guzmán C.A., Sarin S.K.
(2011)
Gene expression profiles of T cells from hepatitis E virus infected patients in acute and resolving phase
Journal of Clinical Immunology,
31
(3)
Author count: 10
Fleissner D., Frede A., Knott M., Knuschke T., Geffers R., Hansen W., Dobos G., Langhorst J., ... , Buer J., Westendorf A.M.
(2011)
Generation and function of immunosuppressive human and murine CD8(+) T cells by transforming growth factor-b[beta] and retinoic acid
Immunology,
134
(1)
Author count: 8
Frank S., Klockgether J., Hagendorf P., Geffers Robert*, Schock U., Pohl T., ... , Davenport C.F., Tummler B.
(2011)
Pseudomonas putida KT2440 genome update by cDNA sequencing and microarray transcriptomics
Environmental Microbiology,
13
(5)
Author count: 10
Froese N., Kattih B., Breitbart A., Grund A., Geffers R., Molkentin J.D., Kispert A., Wollert K.C., ... , Drexler H., Heineke J.
(2011)
GATA6 promotes angiogenic function and survival in endothelial cells by suppression of autocrine transforming growth factor b[beta]/activin receptor-like kinase 5 signaling
Journal of Biological Chemistry,
286
(7)
Author count: 9
Schenk U., Frascoli M., Proietti M., Geffers Robert*, Traggiai E., Buer J., Ricordi C., ... , Westendorf A.M., Grassi F.
(2011)
ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X Receptors
Science Signaling,
4
(162)
Author count: 11
do Valle T.Z., Billecocq A., Guillemot L., Alberts R., Gommet C., Geffers Robert*, Calabrese K., Schughart Klaus*, Bouloy M., ... , Montagutelli X., Panthier J.J.
(2010)
A new mouse model reveals a critical role for host innate immunity in resistance to Rift Valley fever
Journal of Immunology,
185
(10)
Author count: 4
Gekara N.O., Zietara N., Geffers Robert*, Weiss Siegfried*
(2010)
Listeria monocytogenes induces T cell receptor unresponsiveness through pore-forming toxin listeriolysin O
Journal of Infectious Diseases,
202
(11)
Author count: 5
Fleissner D., Hansen W., Geffers Robert*, Buer J., Westendorf A.M.
(2010)
Local induction of immunosuppressive CD8+ T cells in the gut-associated lymphoid tissues
PLoS ONE,
5
(10)
Author count: 12
Lahl K., Mayer C.T., Bopp T., Hühn Jochen*, Loddenkemper C., Eberl G., Wirnsberger G., Dornmair K., Geffers Robert*, Schmitt E., ... , Buer J., Sparwasser T.
(2009)
Nonfunctional regulatory T cells and defective control of Th2 cytokine production in natural scurfy mutant mice
Journal of Immunology,
183
(9)
Author count: 6
Leonhardt J., Kuebler J.F., Turowski C., Tschernig T., Geffers Robert*, Petersen C.
(2010)
Susceptibility to experimental biliary atresia linked to different hepatic gene expression profiles in two mouse strains
Hepatology Research,
40
(2)
Author count: 5
Micklinghoff J.C., Schmidt M., Geffers Robert*, Tegge Werner*, Bange F.C.
(2010)
Analysis of expression and regulatory functions of the ribosome-binding protein TypA in Mycobacterium tuberculosis under stress conditions
Archives of Microbiology,
192
(6)
Author count: 7
Hansen W., Westendorf A.M., Toepfer T., Mauel S., Geffers Robert*, ... , Gruber A.D., Buer J.
(2010)
Inflammation in vivo is modulated by GPR83 isoform-4 but not GPR83 isoform-1 expression in regulatory T cells
Genes and Immunity,
11
(4)
Author count: 7
Dietrich N., Rohde Manfred*, Geffers Robert*, Kroger A., Hauser Hansjörg*, ... , Weiss Siegfried*, Gekara N.O.
(2010)
Mast cells elicit proinflammatory but not type I interferon responses upon activation of TLRs by bacteria
Proceeding of the National Academy of Sciences of the United States of America,
107
(19)
Author count: 19
Stegmann K.A., Björkström N.K., Liermann H., Ciesek S., Riese P., Wiegand J., Hadem J., Suneetha P.V., Jaroszewicz J., Wang C., Schlaphoff V., Fytili P., Cornberg M., Manns M.P., Geffers R., Pietschmann T., Guzmán C.A., ... , Ljunggren H.-G., Wedemeyer H.
(2010)
Interf alpha-induced TRAIL on human NK cells is associated with control of hepatitis C virus infection
Gastroenterology,
138
(5)
Author count: 11
Macke L., Garritsen H.S., Meyring W., Hannig H., Pagelow U., Wormann B., Piechaczek C., Geffers Robert*, Rohde Manfred*, ... , Lindenmaier Werner*, Dittmar Kurt E.*
(2010)
Evaluating maturation and genetic modification of human dendritic cells in a new polyolefin cell culture bag system
Transfusion,
50
(4)
Author count: 9
Garritsen H.S., Macke L., Meyring W., Hannig H., Pagelow U., Wormann B., Geffers Robert*, ... , Dittmar Kurt E.*, Lindenmaier Werner*
(2010)
Efficient generation of clinical-grade genetically modified dendritic cells for presentation of multiple tumor-associated proteins
Transfusion,
50
(4)
Author count: 8
Christgen M., Geffers Robert*, Ballmaier M., Christgen H., Poczkaj J., Krech T., ... , Kreipe H., Lehmann U.
(2010)
Down-regulation of the fetal stem cell factor SOX17 by H33342: a mechanism responsible for differential gene expression in breast cancer side population cells
Journal of Biological Chemistry,
285
(9)
Author count: 14
Malm S., Tiffert Y., Micklinghoff J., Schultze S., Joost I., Weber I., Horst S., Ackermann B., Schmidt M., Wohlleben W., Ehlers S., Geffers R., ... , Reuther J., Bange F.C.
(2009)
The roles of the nitrate reductase NarGHJI, the nitrite reductase NirBD and the response regulator GlnR in nitrate assimilation of Mycobacterium tuberculosis
Microbiology,
155
(Pt 4)
Author count: 19
Probst-Kepper M., Geffers R., Kroger A., Viegas N., Erck C., Hecht H.-J., Lünsdorf H., Roubin R., Moharregh-Khiabani D., Wagner K., Ocklenburg F., Jeron A., Garritsen H., Arstila T.P., Kekalainen E., Balling R., Hauser H., ... , Buer J., Weiss S.
(2009)
GARP: a key receptor controlling FOXP3 in human regulatory T cells
Journal of Cellular and Molecular Medicine,
13
(9)
Author count: 10
Alberts R., Srivastava B., Wu H., Viegas N., Geffers Robert*, Klawonn F., Novoselova N., Zaverucha do V, ... , Panthier J.J., Schughart Klaus*
(2010)
Gene expression changes in the host response between resistant and susceptible inbred mouse strains after influenza A infection
Microbes and Infection,
12
(4)
Author count: 6
Micklinghoff J.C., Breitinger K.J., Schmidt M., Geffers Robert*, Eikmanns B.J., Bange F.C.
(2009)
Role of the transcriptional regulator RamB (Rv0465c) in the control of the glyoxylate cycle in Mycobacterium tuberculosis
Journal of Bacteriology,
191
(23)
Author count: 5
Klebensberger J., Birkenmaier A., Geffers Robert*, Kjelleberg S., Philipp B.
(2009)
SiaA and SiaD are essential for inducing autoaggregation as a specific response to detergent stress in Pseudomonas aeruginosa
Environmental Microbiology,
11
(12)
Author count: 9
Stark L., Matussek A., Strindhall J., Geffers Robert*, Buer J., Kihlstrom E., Monnecke S., ... , Lofgren S., Lindgren P.E.
(2009)
Staphylococcus aureus isolates from blood and anterior nares induce similar innate immune responses in endothelial cells
APMIS,
117
(11)
Author count: 5
Njau F., Geffers Robert*, Thalmann J., Haller H., Wagner A.D.
(2009)
Restriction of Chlamydia pneumoniae replication in human dendritic cell by activation of indoleamine 2,3-dioxygenase
Microbes and Infection,
11
(13)
Author count: 9
Garritsen H.S.P., Xiu-Cheng Fan A., Lenz D., Hannig H., Zhong X.Y., Geffers Robert*, Lindenmaier Werner*, ... , Dittmar Kurt E.J.*, Wörmann B.
(2009)
Molecular diagnostics in transfusion medicine: In capillary, on a chip, in silico, or in flight?
Transfusion Medicine and Hemotherapy,
36
(3)
Author count: 8
Jeron A., Pfoertner S., Bruder Dunja*, Geffers Robert*, Hammerer P., Hofmann R., ... , Buer J., Schrader A.J.
(2009)
Frequency and Gene Expression Profile of Regulatory T Cells in Renal Cell Carcinoma
Tumor Biology,
30
(3)
Author count: 8
Pati N.T., Geffers R., Sukriti Hissar S., Riese P., Toepfer T., Buer J., ... , Guzmán C.A., Sarin S.K.
(2009)
Gene expression signatures of peripheral CD4+ T cells clearly discriminate between patients with acute and chronic hepatitis B viral infection
Hepatology,
49
(3)
Author count: 5
Dötsch A., Pommerenke C., Bredenbruch F., Geffers Robert*, Häußler Susanne*
(2009)
Evaluation of a microarray-hybridization based method applicable for discovery of single nucleotide polymorphisms (SNPs) in the Pseudomonas aeruginosa genome
BMC GENOMICS,
10
Author count: 8
Srivastava B., Blazejewska P., Hessmann M., Bruder D., Geffers Robert*, Mauel S., ... , Gruber A.D., Schughart Klaus*
(2009)
Host genetic background strongly influences the response to influenza a virus infections
PLoS ONE,
4
(3)
Author count: 8
Ukena S.N., Koenecke C., Geffers Robert*, Fuehner T., Welte T., Ganser A., ... , Buer J., Franzke A.
(2009)
T helper type 2 differentiation is associated with induction of antibacterial defense mechanisms in blood lymphocytes of patients with sarcoidosis
Immunological Investigations,
38
(1)
Author count: 10
Quentmeier H., Geffers Robert*, Jost E., MacLeod R.A., Nagel S., Rohrs S., Romani J., Scherr M., ... , Zaborski M., Drexler H.G.
(2008)
SOCS2: inhibitor of JAK2V617F-mediated signal transduction
Leukemia,
22
(12)
Author count: 10
Bitterle E., Hofer T., Karg E., Ferron G.A., Schroeppel A., Tippe A., Geffers Robert*, Kreyling W.G., ... , Maier K.L., Heyder J.
(2004)
A new in-vitro evice for exposure of epithelial cells to airborne ultrafine elemental carbon particles at the air-liquid interface
Journal of Aerosol Science,
35
((Suppl. 2))
Author count: 9
Block J., Stradal T.E.B., Hanisch J., Geffers R., Kostler S.A., Urban E., Small J.V., ... , Rottner K., Faix J.
(2008)
Filopodia formation induced by active mDia2/Drf3
Journal of Microscopy,
231
(3)
Author count: 5
Basler T., Geffers Robert*, Weiss Siegfried*, Valentin-Weigand P., Goethe R.
(2008)
Mycobacterium avium subspecies induce differential expression of pro-inflammatory mediators in a murine macrophage model: Evidence for enhanced pathogenicity of
Immunobiology,
213
(9-10)
Author count: 11
Marhenke S., Lamle J., Buitrago-Molina L.E., Canon J.M., Geffers Robert*, Finegold M., Sporn M., Yamamoto M., Manns M.P., ... , Grompe M., Vogel A.
(2008)
Activation of nuclear factor E2-related factor 2 in hereditary tyrosinemia type 1 and its role in survival and tumor development
Hepatology,
48
(2)
Author count: 7
Depke M., Fusch G., Domanska G., Geffers Robert*, Volker U., ... , Schuett C., Kiank C.
(2008)
Hypermetabolic syndrome as a consequence of repeated psychological stress in mice
Endocrinology,
149
(6)
Author count: 17
Nickeleit I., Zender S., Sasse Florenz*, Geffers Robert*, Brandes G., Sorensen I., Steinmetz Heinrich*, Kubicka S., Carlomagno T., Menche D., Gutgemann I., Buer J., Gossler A., Manns M.P., Kalesse Markus*, ... , Frank Ronald*, Malek N.P.
(2008)
Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition
Cancer Cell,
14
(1)
Author count: 9
Lamle J., Marhenke S., Borlak J., von Wasielewski R., Eriksson C.J., Geffers Robert*, Manns M.P., ... , Yamamoto M., Vogel A.
(2008)
Nuclear factor-eythroid 2-related factor 2 prevents alcohol-induced fulminant liver injury
Gastroenterology,
134
(4)
Author count: 7
Seifert O., Bayat A., Geffers Robert*, Dienus K., Buer J., ... , Lofgren S., Matussek A.
(2008)
Identification of unique gene expression patterns within different lesional sites of keloids
Wound Repair and Regeneration,
16
(2)
Author count: 9
Sztajer Helena*, Lemme A., Vilchez R., Schulz S., Geffers Robert*, Yip C.Y.Y., Levesque C.M., ... , Cvitkovitch D.G., Wagner-Döbler Irene*
(2008)
Autoinducer-2-regulated genes in Streptococcus mutans
Journal of Bacteriology,
190
(1)
Author count: 10
Hansen W., Westendorf A.M., Reinwald S., Bruder Dunja*, Deppenmeier S., Gröbe Lothar*, Probst-Kepper Michael*, Gruber A.D., ... , Geffers Robert*, Buer Jan*
(2007)
Chronic antigen stimulation in vivo induces a distinct population of antigen-specific Foxp3 -
Journal of Immunology,
179
Author count: 4
Zheng P., Sun J., Geffers Robert*, Zeng An-Ping*
(2007)
Functional characterization of the gene PA2384 in large-scale gene regulation in response to iron starvation in Pseudomonas aeruginosa
Journal of Biotechnology,
132
(4)
Author count: 3
Müller S., Geffers Robert*, Gunther S.
(2007)
Analysis of gene expression in Lassa virus-infected HuH-7 cells
Journal of General Virology,
88
Author count: 6
Goldmann O., von Kockritz-Blickwede M., Holtje C., Chhatwal G.S., Geffers R., Medina E.
(2007)
Transcriptome analysis of murine macrophages in response to infection with Streptococcus pyogenes
Infection and Immunity,
75
(8)
Author count: 8
Fleige A., Alberti S., Gröbe L., Frischmann U., Geffers R., Müller W., ... , Nordheim A., Schippers A.
(2007)
Serum response factor contributes selectively to lymphocyte development
The Journal of Biological Chemistry,
282
(33)
Author count: 7
Davies M.R., McMillan D.J., Baiko R.G., Barroso V., Geffers Robert*, ... , Sriprakash K.S., Chhatwal Gursharan S*.
(2007)
Virulence profiling of Streptococcus dysgalactiae
Clinical Infectious Diseases,
44
(11)
Author count: 6
McMillan D.J., Geffers Robert*, Buer Jan*, Vlaminckx B.J.M., Sriprakash K.S., Chhatwal Gursharan S*.
(2007)
Variations in the distribution of genes encoding virulence and extracellular proteins in group A streptococcus are largely restricted to eleven genomic loci
Microbes and Infection,
9
(3)
Author count: 17
Bohn G., Allroth A., Brandes G., Thiel J., Glocker E., Schäffer A.A., Rathinam C., Taub N., Teis D., Zeidler C., Dewey R.A., Geffers Robert*, Buer Jan*, Huber L.A., Welte K., ... , Grimbacher B., Klein C.
(2007)
A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14
Nature medicine,
13
(1)
Author count: 15
Bohn G., Allroth A., Thiel J., Schaffer A.A., Brandes G.,