Veranstaltungsarchiv

04.06.2013, 17:15 - Talk - Wissenschaftlich

Luigi Vezzulli "Ecology of pathogenic Vibrio species in the light of climate Change"

Vibrios are among the most common bacteria that inhabit surface waters throughout the world and are responsible for a number of severe infections both in humans and animals. Most recently, on going climate change and especially sea surface warming are believed to promote Vibrio proliferation in coastal waters and outbreak of their associated diseases. According to this, a retrospective molecular study of formalin-fixed plankton samples collected by the Continuous Plankton Recorder (CPR) survey in the North Sea has provided the first evidence for a positive and significant relationship between Sea Surface Temperature (SST) and Vibrio abundances, including V. cholera, over a multidecadal scale. These findings provide support for the view that global warming is having a strong impact on the composition of marine Vibrio communities, with potential important implications for human and animal health.

04.06.2013, 17:00 - Talk - Wissenschaftlich

Andreas Bechthold "Novel natural products by awaking silent gene clusters and by creating artificial biosynthetic genes"

04.06.2013, 16:15 - Talk - Wissenschaftlich

José A. Salas "Natural products biosynthesis in actinomycetes: cluster engineering and activation"

May 30 – June 1, 2013 - Talk - Wissenschaftlich

6th International Workshop “Interferon and Infection”

28.05.2013, 16:30 - Talk - Wissenschaftlich

Eric Vivier "Natural Killer Cells, Innate Lymphoid Cells and Innate Immunity"

Natural Killer (NK) cells are lymphocytes of the innate immune system, involved in the elimination of tumors and microbe-infected cells. NK cells sense their cellular targets via inhibitory receptors that recognise surface molecules expressed at steady-state and via activating receptors that recognise stress-induced molecules. NK cells thus express an array of receptors which detect these molecular changes and which trigger cell-mediated cytotoxicity and cytokine production when engaged. In addition NK cells can kill target cells by antibody-dependent cell cytotoxicity if the cells have been tagged by antibodies. Besides NK cells, a novel group of innate lymphoid cells (ILCs) is emerging. The biology of both NK and ILCs will be reviewed.

25.05.2013 - Special Event - Öffentlich

Tag der offenen Tür 2013

Etwa ein Viertel aller Todesfälle weltweit geht auf Infektionen zurück. Deshalb untersuchen wir am Helmholtz-Zentrum für Infektionsforschung, wie Infektionserreger Krankheiten auslösen und wie sich das Immunsystem des Körpers gegen Bakterien und Viren zur Wehr setzt. So schaffen die Wissenschaftler die Grundlagen für neue Diagnoseverfahren, Medikamente und Wirkstoffe.

Wenn Sie mit der Braunschweiger Verkehrs-AG innerhalb von Braunschweig anreisen, fordern Sie Ihren kostenlosen Fahrschein per E-Mail unter Angabe Ihrer Adresse an. Wir senden Ihnen den Coupon, mit dem Sie kostenlos zum Tag der offenen Tür am HZI an- und abreisen können, dann per Post zu. Solange der Vorrat reicht!

Die Buslinie 431 fährt zwischen 11:00 und 17:45 Uhr außerplanmäßig viertelstündlich die Haltestelle „Senefelderstraße“ an - direkt an der alten Pforte.

22.05.2013, 17:15 - HZI Colloquium - Wissenschaftlich

Richard Stanton "Human cytomegalovirus - why the viral genome really matters"

HCMV is a ubiquitous pathogen, with a vaccine designated highest priority. However researchers are frequently forced to work with virus strains that have been passaged in vitro, and these strains behave very differently to clinical virus, particularly in areas that are critical to vaccine development. My work focusses on understanding how and why virus genomes change when passaged and how to stop these changes occurring, enabling anti-viral strategies to be developed using virus that accurately represents the causative agent of disease.

15.05.2013, 17:15 - HZI Colloquium - Wissenschaftlich

Christian Freund "Steering immune cell recognition from inside the cell"

Our group is interested in the understanding and manipulation of molecular interactions that govern the assembly of protein complexes. The focus is on recognition events that mediate critical events in immune cell activation. In particular we study mechanistic aspects of MHC II antigen presentation, T cell activation and adhesion.

08.05.2013, 17:15 - HZI Colloquium - Wissenschaftlich

Axel Haverich "This Heart is mine – Autologisation of Surgical Implants"

Both, regeneration and infection play a major role regarding the long term prognosis of biomedical implants. This finds true for biological implants, e.g. transplanted organs, as well as for metallic devices such as pacemakers and artificial hearts. Interestingly, the crosstalk between regeneration and infection has recently gained tremendous interest, since biological concepts of regeneration often prevent or treat infection of such devices.

The economic impact of medical device infection is dramatic, the consequences for the individual patient dire. A completely ingrown implant will never be prone to infection, a rule also true for autologous (the patient’s own) material used as replacement, e.g. valves or bypass material in heart surgery. Allogenic (from different individuals) or xenogenic (from different species) implants, however, are constantly attacked by the immune system, and infectious episodes have repeatedly shown to enhance this process of acute and chronic graft rejection.

Against the background of increasing numbers of medical device implantation due to our aging population, prevention and treatment of implant infection will be a prime target of future biomedical research. Biological implants, biofunctionalisation of implant surfaces to foster rapid ingrowth of autologous cells or incorporating anti-infectious agents as well as biologisation of surfaces by cell seeding using autologous material are the three most prominent avenues of research today.

The presentation will give the medical background from pertinent surgical disciplines, examples of the impact of device infection, and strategies currently pursued by researchers at MHH. Also, the structure and focus of REBIRTH, NIFE and the recently granted project ‘Biofabrication’ will be explained, advertising areas of potential future cooperation between MHH and HZI.

07.05.2013, 09:30 - Symposium - Wissenschaftlich

1st International Symposium of the Virtual Institute "Viral Strategies of Immune Evasion" VISTRIE