Sites of the Helmholtz Centre
The Sites of the Helmholtz Centre for Infection Research are distributed all over Germany. In addition to the main campus in Braunschweig, there are facilities in 4 other cities: Hamburg, Hanover, Saarbrücken and Würzburg.
The vision of the Centre for Individualised Infection Medicine (CiiM) is to individualise the management of infectious diseases. CiiM is a joint venture of the Helmholtz Centre for Infection Research (HZI) and the Hannover Medical School (MHH) and was founded as an initially virtual network in 2015. Research activities at the center aim to identify individual parameters that influence the progress of infection and to translate these findings into optimized and individualised care of patients with infectious diseases.
The two CiiM directors Yang Li and Markus Cornberg are responsible for the establishment of the CiiM and represent the CiiM in scientific matters. The focus lays on answering clinically relevant questions in the field of infectious medicine with the aim of a treatment tailored to the individual patient. The two directors of the CiiM ideally ensure that the clinic is more closely linked to research and data science.
Yang Li has headed the Department of Computational Biology for Individualised Medicine at the CiiM and the HZI since 2019 and was also appointed Director of the CiiM. The focus of her research is on understanding the molecular mechanisms of immune-related/infectious diseases through integration of multi-omics data.
Yang Li obtained her PhD in bioinformatics at the University of Groningen (The Netherlands) in 2010. She received the National Bioinformatics Young Investigator Award of 2011 in the Netherlands. In 2013, she received her first personal grant: an NWO-VENI grant from the Dutch Research Council, which is an innovative research program to supporting talented and outstanding young researchers in the Netherlands. Thereafter, Dr. Li became an independent researcher and started to build her own research team to further her interests in the complex genetics of human diseases using the multi-omics datasets. Later, she received other prestigious personal grants including a ZonMW-Offroad and a Hypatia grant. Besides that she is co-applicant on several large consortium grants. She has published ~70 scientific articles including publications in Cell, Nature Medicine, Nature Immunology and Cell Reports. She also served as reviewer for many journals such as Nature Ecology & Evolution, Bioinformatics, Journal of the Royal Statistical Society (UK) and Genetics.
Markus Cornberg, MD is Professor of Medicine for Infectious disease with emphasis on hepatitis and attending physician in the Department of Gastroenterology, Hepatology and Endocrinology at Hannover Medical School responsible for the infectiousdisease ward and the hepatitisoutpatient clinic. In 2019 he was appointed Clinical Director of the HZI and Director of the Centre for Individualised Infection Medicine (CiiM). He is also the managing director of the German Competence Network for Viral Hepatitis (HepNet) and medical secretary of the German Liver Foundation.
Markus Cornberg has a long-term interest in infectious diseases with a focus on viral liver diseases. In 2007, 2011 and in 2017 he coordinated the German consensus process for the management of hepatitis B. In 2012 he was the German representative in the panel for the EASL Practice Guidelines for Hepatitis B. Since 2017 he is member of the scientific committee and the governing board of EASL. He has published more than 150 scientific articles on viral hepatitis and serves as a reviewer for several journals such as the Lancet, Gastroenterology, Hepatology, GUT, and the Journal of Hepatology.
Centre for Individualised Infection Medicine