Recombinant Protein Expression

Proteins play an important role in infectious diseases. They not only take over central functions in the invasion and replication of pathogens, but also in the defensive reaction of our body or as a drug. For a detailed investigation of proteins, scientists often require them in large amounts and extremely pure state. Read more about how proteins are artificially produced and purified.

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Instruct

Access to Hightech Infrastructure all over Europe

Making the most advanced technologies available to researchers all over Europe is the goal of the initiative “Instruct”. Fifteen research institutes from eight countries have launched this cooperation in Brussels. Many more are supposed to follow and further broaden the shared technological basis. The HZI and four other German institutes are part of this alliance.

Instruct’s main focus is structural biology, a scientific discipline aiming to resolve the three-dimensional structure of biological molecules. The structure provides important insights into the biological function of these molecules, which in turn may lead to new concepts in understanding and fighting diseases.

The central hub of the Instruct network is the website www.structuralbiology.eu. This platform provides access to high-end technologies which most single research groups could not afford. Examples are highly specialized cell culture methods for protein expression housed at the HZI as well as newest imaging technologies like cryo-electron tomography or the use of electron accelerators for the analysis of molecular structures.

Instruct Signing Ceremony in Brussels on 23rd February 2012

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