Central Facility for Microscopy

Light microscopy and electron microscopy are excellent high resolution tools to investigate the adhesion and invasion mechanisms of pathogenic bacteria. High resolution electron microscopy permits to examine and unravel pathogenicity mechanisms on a morphological basis.ZEIM offers equipment and highly sophisticated expertise for the preparation and observation of biological samples.

Leader

Selected publications

Grüneboom A., Hawwari I., Weidner D., Culemann S., Müller S., Henneberg S., Brenzel A., Merz S., Bornemann L., Zec K., Wuelling M., Kling L., Hasenberg M., Voortmann S., Lang S., Baum W., Ohs A., Kraff O., Quick HH., Jäger M., Landgräber S., Dudda M., Danuser R., Stein J.V., Rohde M., Gelse K., Garbe AI., Adamczykk A., Westendorf AM., Hoffmann D., Christiansen S., Engel DR., Vortkamp A., Krönke G., Herrmann M., Kamradt T., Schett G., Hasenberg A., Gunzer M. (2019) A network of trans-cortical capillaries as mainstay for blood cisculation in long bones.  Nat Metab.: 1 (2) pp: 236-250. doi: 10.1038/s42255-018-0016-5  

Puhm F., Afonyushkin T., Resch U., Obermayer G., Rohde M., Penz T., Schuster M., Wagner G., Rendeiro AF., Melki I., Kaun C., Wojta J., Bock C., Jilma B., Mackman N., Boilard E., Binder CJ. (2019) Mitochondria are a subset of extracellular vesicles released by activated monocytes and include type I IFN and TNF responses in endothelial cells. Circ Res. Jun 21;125(1):43-52. doi: 10.1161/CIRCRESAHA.118.314601

Wiegand S., Jogler M., Boedeker C., Pinto D., Vollmers J., Rivas-Marín E., Kohn T.,  Peeters SH., Heuer A., Rast P., Oberbeckmann S., Bunk B., Jeske O., Meyerdierks A., van Niftrik L.,  Storesund JE., Kallscheuer N., Lücker S., Lage OM., Pohl T., Merkel BJ., Hornburger P., Müller R-W., Brümmer F., Labrenz M., Spormann AM., op den Camp H., Overmann J., Amann R., Jetten MSM., Piel J., Mascher T.,  Medema MH., Devos DP., Kaster A-K., Øvreås L., Rohde M., Galperin MY., Jogler C. Cultivation and functional characterization of 79 Planctomyces uncovers their unique biology. Nat Microbiol. In press

Müsken M., Pawar V., Schwebs T., Bähre H., Felgner S., Weiss S., Häussler S. (2018) Breaking the vicious cycle of antibiotic killing and regrowth of biofilm residing Pseudomonas aeruginosa. Antimicrob Agents and Chemother. 62(12):e01635-18. doi: 10.1128/AAC.01635-18

Boedeker C.; Schüler M.; Reintjes G.; Jeske O.; van Teeseling MC.; Jogler M.; Rast P.; Borchert D.; Devos DP.; Kucklick M.; Schaffer M.; Kolter R.; van Niftrik L.; Engelmann S.; Amann R.; Rohde M.; Engelhardt H.; Jogler C. (2017) Determining the bacterial cell biology of Planctomycetes. Nat Commun.: 8:14853. doi: 10.1038/ncomms14853

Vollständige Publikationsliste

 

Samples

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