Flow Cytometry and Cell Sorting

Our organism is made of many different cells that are specialized to perform specific tasks. As long as they work together in the collective, we will stay healthy – do they change or are they changed by pathogens, we become unbalanced and sick. The Flow Cytometry and Cell Sorting platform provides the instrumentation and expert knowledge for the phenotypic identification and functional analysis of cells at the single cell level.


Selected Publications

TCR signalling network organization at the immunological synapses of murine regulatory T cells. van Ham M, Teich R, Philipsen L, Niemz J, Amsberg N, Wissing J, Nimtz M, Gröbe L, Kliche S, Thiel N, Klawonn F, Hubo M, Jonuleit H, Reichardt P, Müller AJ, Huehn J, Jänsch L. Eur J Immunol. 2017 Aug 17. DOI:10.1002/eji.201747041. [Epub ahead of print]

Development of a unique epigenetic signature during in vivo Th17 differentiation. Yang BH, Floess S, Hagemann S, Deyneko IV, Groebe L, Pezoldt J, Sparwasser T, Lochner M, Huehn J. Nucleic Acids Res. 2015 Feb 18;43(3):1537-48. DOI:10.1093/nar/gkv014. Epub 2015 Jan 15.

Proteome analysis of distinct developmental stages of human natural killer (NK) cells. Scheiter M, Lau U, van Ham M, Bulitta B, Gröbe L, Garritsen H, Klawonn F, König S, Jänsch L. Mol Cell Proteomics. 2013 May;12(5):1099-114. DOI:10.1074/mcp.M112.024596. Epub 2013 Jan 13.

Streamlining homogeneous glycoprotein production for biophysical and structural applications by targeted cell line development. Wilke S, Groebe L, Maffenbeier V, Jäger V, Gossen M, Josewski J, Duda A, Polle L, Owens RJ, Wirth D, Heinz DW, van den Heuvel J, Büssow K. PLoS One. 2011;6(12):e27829. DOI:10.1371/journal.pone.0027829. Epub 2011 Dec 9. 

Phenotypic alterations in type II alveolar epithelial cells in CD4+ T cell mediated lung inflammation. Gereke M, Gröbe L, Prettin S, Kasper M, Deppenmeier S, Gruber AD, Enelow RI, Buer J, Bruder D. Respir Res. 2007 Jul 4;8:47.

Full Publicationlist

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