Animal Facility

To be able to investigate diseases, understand the relationships between pathogens and their host and to develop novel strategies against pathogens, the scientists at the HZI depend on experiments that involve the use of laboratory animals. The HZI runs an Animal Facility on its campus, the so-called Animal House. The central task of this service unit is the breeding and keeping of laboratory mice as well as provision of services for the scientists of the HZI, centered around laboratory animal science.


Dr Bastian Pasche

Complex immune reactions are dependent on an intact organsim – therefore we are not able to completely resign from animal experiments, despite of alternative methods

Dr Bastian Pasche


Bastian Pasche studied biology in Göttingen. After his Diploma thesis he did his PhD in the Graduate School „Molecular Genetic of Development“ on promoter analysis and expression studies of human and murine Foxq1. Part of this work was the generation of a Foxq1 knockout mouse.

After a short postdoc at the Institute of Human Genetics at the University of Göttingen he started in 2002 as postdoc in the junior research group „Infection Genetic“ at the GBF, the predecessor institution of the HZI. He established different infection models in the context of national (NGFN) and european (EUMORPHIA) projects in close collaboration with the German Mouse Clinic at the Helmholtz Center München.

From  2006 to 2010 he worked as a scientist in the Department „Experimental Mouse Genetics“ at the HZI, continuing his work in European projects (EUMODIC). These european consortia are now part of the International Mouse Phenotyping Consortium

2010 he moved to the Central Animal Facility of the HZI. As deputy head he was responsible for implementing and running the new experimental barriers (S2, S3**, S3). A second focus was on animal welfare, where he strongly promoted the establishment of lab animal courses at the HZI.

Since 2015 he is head of the Central Animal Facility.

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