Model Systems for Infection and Immunity
Leader
Prof Dr Dagmar Wirth
We develop models for studying questions of infection and immunity – using cutting-edge molecular biology strategies and cellular systems for in-vitro studies as well as transgenic mouse systems for in-vivo studies.
Dagmar Wirth studied chemistry in Braunschweig. She began focusing on gene regulation in mammalian cells as part of her doctoral work at GBF – today’s HZI – with a special focus on chromosomal elements that affect gene expression. As a post-doc, she conducted research on recombination in mammalian cells and viruses and developed recombinant viruses for application in biotechnology and gene therapy.
Following her work as a scientist in the Department of Clinical Immunology at the Medical University in Hannover, she returned in 2004 to assume her current role as principal investigator for the project ‘Immune evasion in chronic infections’ and as head of the research group ‘Model Systems for Infection and Immunity’ (MSYS).
One underlying activity of her research in MSYS is the generation of genetically modified mice with predictable expression properties. To provide this expertise to all research groups of the center, in 2012, the Service Unit "Transgenic Mice (TGSM)" was initiated which is also headed by Dagmar Wirth.
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Bachelor & Master
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