Innate Immunity and Infection
The moment a pathogen, which has successfully entered the body, is recognized, the body quickly mobilizes its defenses. Interferons are molecules that are counted among the body’s first line of defense. They prevent proliferation and the spread of viruses in the body and serve to alert the immune system. Read here about the different ways we use to try and decode this system, all in an effort to find new approaches to infectious disease prevention and therapy.
Dr Andrea Kröger
A pathogen’s initial contact with the host is crucial for the outcome of an infection. The host’s initial reactions will decide whether the host is able to assert itself or whether it will lead to a chronic infection and more serious illness.
Andrea Kröger studied biology at the Technische Universität Braunschweig. During her diploma thesis at HZI – at that time still called GBF – she was already doing research on bacteria. Following this, she earned her doctoral degree, focusing on tumor suppression by interferon regulatory factor-1. Ever since, she has been conducting research within HZI’s Department of Gene Regulation and Differentiation with a special focus on immunological questions. Since 2010, as principal investigator of the “Interferons in Immune Defense and Immunity“ project, Andrea Kröger is searching for the mechanisms used by the interferon system to fight infections and influence protective immune responses. Since 2012, she heads the Innate Immunity and Infection research group.
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