Epidemiological and statistical methods

The choice of the right method is essential in epidemiology. Which sample size is necessary to verify an association between a risk factor and a disease, taking potential statistic variations into account? To which degree do other risk factors for the examined disease distort the outcome of a study? In order to get meaningful results, these questions must be evaluated for every new scenario.



Chatzikyrkou C, Eichler J, Karch A, Clajus C, Scurt FG, Ramackers W, Lehner F, Menne J, Haller H, Mertens PR & Schiffer M. (2016). Short- and Long-Term Effects of the Use of Raas Blockers Immediately after Renal Transplantation. Blood Press, 1-9. doi: 10.1080/08037051.2016.1182856

Conzen C, Conzen M, Rubsamen N & Mikolajczyk R. (2016). Predictors of the Patient-Centered Outcomes of Surgical Carpal Tunnel Release - a Prospective Cohort Study. BMC Musculoskelet Disord, 17(1), 190. doi: 10.1186/s12891-016-1046-3

Cramm M, Schmitz M, Karch A, Mitrova E, Kuhn F, Schroeder B, Raeber A, Varges D, Kim YS, Satoh K, Collins S, Zerr I. (2016). Stability and Reproducibility Underscore Utility of RT-QuIC for Diagnosis of Creutzfeldt-Jakob Disease. Mol Neurobiol. 53(3):1896-904. doi: 10.1007/s12035-015-9133-2. Epub 2015 Apr 1.

Grylka-Baeschlin S, Petersen A, Karch A & Gross MM. (2016). Labour Duration and Timing of Interventions in Women Planning Vaginal Birth after Caesarean Section. Midwifery, 34, 221-229. doi: 10.1016/j.midw.2015.11.004

Helmer SM, Sebena R, McAlaney J, Petkeviciene J, Salonna F & Mikolajczyk RT. (2016). Perception of High Alcohol Use of Peers Is Associated with High Personal Alcohol Use in First-Year University Students in Three Central and Eastern European Countries. Subst Use Misuse, 1-8. doi: 10.3109/10826084.2016.1162810

Horn J, Karch A, Damm O, Kretzschmar ME, Siedler A, Ultsch B, Weidemann F, Wichmann O, Hengel H, Greiner W & Mikolajczyk RT. (2016). Current and Future Effects of Varicella and Herpes Zoster Vaccination in Germany - Insights from a Mathematical Model in a Country with Universal Varicella Vaccination. Hum Vaccin Immunother, 1-11. doi: 10.1080/21645515.2015.1135279 

Karch A, Koch A, Zapf A, Zerr I, Karch A. Partial verification bias and incorporation bias affect diagnostic studies for biomarkers that are part of an existing composite gold standard. J Clin Epidemiol. 2016 Apr 20. pii: S0895-4356(16)30071-3. doi: 10.1016/j.jclinepi.2016.03.022.

Karch A, Vogelmeier C, Welte T, Bals R, Kauczor HU, Biederer J, Heinrich J, Schulz H, Glaser S, Holle R, Watz H, Korn S, Adaskina N, Biertz F, Vogel C, Vestbo J, Wouters EF, Rabe KF, Sohler S, Koch A & Jorres RA. (2016). The German Copd Cohort Cosyconet: Aims, Methods and Descriptive Analysis of the Study Population at Baseline. Respir Med, 114, 27-37. doi: 10.1016/j.rmed.2016.03.008

Kersting C, Lindemann C, Jacobi C, Lo Baido A, Schneider A, Yurdakul M, Ziegler-Kirbach E, Mikolajczyk R & Garbe E. (2016). [Therapy Goals for Children and Adolescents with Adhd and Their Primary Caregivers. A Content Analysis and Examination of Agreement of Adhd Patients and Their Primary Caregivers]. Gesundheitswesen, 78(1), 34-36. doi: 10.1055/s-0034-1387746

Kersting C, Lindemann C, Mikolajczyk R, Garbe E & Riedel O. (2016). [Optimizing Adhd Treatment? Results of a Pilotstudy of the Adhd Selective Contract in Bremerhaven, Germany]. Psychother Psychosom Med Psychol, 66(5), 187-194. doi: 10.1055/s-0042-100814

Kyu HH, […], Karch A, […], Murray CJ & Vos T. (2016). Global and National Burden of Diseases and Injuries among Children and Adolescents between 1990 and 2013: Findings from the Global Burden of Disease 2013 Study. JAMA Pediatr, 170(3), 267-287. doi: 10.1001/jamapediatrics.2015.4276

Llorens F, Schmitz M, Karch A, Cramm M, Lange P, Gherib K, Varges D, Schmidt C, Zerr I & Stoeck K. (2016). Comparative Analysis of Cerebrospinal Fluid Biomarkers in the Differential Diagnosis of Neurodegenerative Dementia. Alzheimers Dement, 12(5), 577-589. doi: 10.1016/j.jalz.2015.10.009

Ohlmeier C, Czwikla J, Enders D, Mikolajczyk R, Blindt R, Horenkamp-Sonntag D, Linder R & Garbe E. (2016). [Percutaneous Coronary Interventions : Use between 2004 and 2012 in Germany]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 59(6), 783-788. doi: 10.1007/s00103-016-2352-5

Raupach-Rosin H, Rubsamen N, Szkopek S, Schmalz O, Karch A, Mikolajczyk R & Castell S. (2016). Care for Mrsa Carriers in the Outpatient Sector: A Survey among Mrsa Carriers and Physicians in Two Regions in Germany. BMC Infect Dis, 16(1), 184. doi: 10.1186/s12879-016-1503-5

Schmitz M, Ebert E, Stoeck K, Karch A, Collins S, Calero M, Sklaviadis T, Laplanche JL, Golanska E, Baldeiras I, Satoh K, Sanchez-Valle R, Ladogana A, Skinningsrud A, Hammarin AL, Mitrova E, Llorens F, Kim YS, Green A, Zerr I. (2016). Validation of 14-3-3 Protein as a Marker in Sporadic Creutzfeldt-Jakob Disease Diagnostic. Mol Neurobiol. 53(4):2189-99. doi: 10.1007/s12035-015-9167-5. Epub 2015 May 7.

Wacker ME, Jorres RA, Karch A, Wilke S, Heinrich J, Karrasch S, Koch A, Schulz H, Watz H, Leidl R, Vogelmeier C & Holle R. (2016). Assessing Health-Related Quality of Life in Copd: Comparing Generic and Disease-Specific Instruments with Focus on Comorbidities. BMC Pulm Med, 16(1), 70. doi: 10.1186/s12890-016-0238-9

Wacker ME, Jorres RA, Schulz H, Heinrich J, Karrasch S, Karch A, Koch A, Peters A, Leidl R, Vogelmeier C & Holle R. (2016). Direct and Indirect Costs of Copd and Its Comorbidities: Results from the German Cosyconet Study. Respir Med, 111, 39-46. doi: 10.1016/j.rmed.2015.12.001

Ye J, Zhang J, Mikolajczyk R, Torloni MR, Gulmezoglu AM & Betran AP. (2016). Association between Rates of Caesarean Section and Maternal and Neonatal Mortality in the 21st Century: A Worldwide Population-Based Ecological Study with Longitudinal Data. Bjog, 123(5), 745-753. doi: 10.1111/1471-0528.13592


Akmatov MK, Kimani-Murage E, Pessler F, Guzman CA, Krause G, Kreienbrock L & Mikolajczyk RT. (2015). Evaluation of Invalid Vaccine Doses in 31 Countries of the Who African Region. Vaccine, 33(7), 892-901. doi: 10.1016/j.vaccine.2014.10.089

Akmatov MK, Rubsamen N, Schultze A, Kemmling Y, Obi N, Gunther K, Ahrens W, Pessler F, Krause G & Mikolajczyk RT. (2015). Diverse Recruitment Strategies Result in Different Participation Percentages in a Web-Based Study, but in Similar Compliance. Int J Public Health. doi: 10.1007/s00038-015-0737-0

Bennett DA, Brayne C, Feigin VL, Barker-Collo S, Brainin M, Davis D, Gallo V, Jette N, Karch A, Kurtzke JF, Lavados PM, Logroscino G, Nagel G, Preux PM, Rothwell PM & Svenson LW. (2015). Development of the Standards of Reporting of Neurological Disorders (Strond) Checklist: A Guideline for the Reporting of Incidence and Prevalence Studies in Neuroepidemiology. Eur J Epidemiol. doi: 10.1007/s10654-015-0034-5

Bennett DA, Brayne C, Feigin VL, Barker-Collo S, Brainin M, Davis D, Gallo V, Jette N, Karch A, Kurtzke JF, Lavados PM, Logroscino G, Nagel G, Preux PM, Rothwell PM & Svenson LW. (2015). Development of the Standards of Reporting of Neurological Disorders (Strond) Checklist: A Guideline for the Reporting of Incidence and Prevalence Studies in Neuroepidemiology. Eur J Epidemiol. doi: 10.1212/WNL.0000000000001866. Epub 2015 Jul 10.

Betran AP, Torloni MR, Zhang J, Ye J, Mikolajczyk R, Deneux-Tharaux C, Oladapo OT, Souza JP, Tuncalp O, Vogel JP & Gulmezoglu AM. (2015). What Is the Optimal Rate of Caesarean Section at Population Level? A Systematic Review of Ecologic Studies. Reprod Health, 12(1), 57. doi: 10.1186/s12978-015-0043-6

Cramm M, Schmitz M, Karch A, Zafar S, Varges D, Mitrova E, Schroeder B, Raeber A, Kuhn F, Zerr I.  (2015). Characteristic CSF prion seeding efficiency in humans with prion diseases. Mol Neurobiol. 51(1):396-405. doi: 10.1007/s12035-014-8709-6. Epub 2014 May 9.

Damm O, Ultsch B, Horn J, Mikolajczyk RT, Greiner W & Wichmann O. (2015). Systematic Review of Models Assessing the Economic Value of Routine Varicella and Herpes Zoster Vaccination in High-Income Countries. BMC Public Health, 15, 533. doi: 10.1186/s12889-015-1861-8

Damm O, Horn J, Mikolajczyk R, Greiner W, Siedler A, Weidemann F, Wichmann O, Kretzschmar M & Ultsch B. (2015). Health Economic Evaluation of Different Vaccination Strategies against Varicella and Herpes Zoster in Germany. Value Health, 18(7), A588. doi: 10.1016/j.jval.2015.09.1503

Forouzanfar MH, […] Karch A, […] Vos T, Murray CJ. (2015). Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet, 386(10010):2287-323. doi: 10.1016/S0140-6736(15)00128-2. Epub 2015 Sep 11.

Gross MM, Matterne A, Berlage S, Kaiser A, Lack N, Macher-Heidrich S, Misselwitz B, Bahlmann F, Falbrede J, Hillemanns P, von Kaisenberg C, von Koch FE, Schild RL, Stepan H, Devane D & Mikolajczyk R. (2015). Interinstitutional Variations in Mode of Birth after a Previous Caesarean Section: A Cross-Sectional Study in Six German Hospitals. J Perinat Med, 43(2), 177-184. doi: 10.1515/jpm-2014-0108

Karch A. (2015). Standardized Surveillance of Prion Diseases in Resource-Poor Settings Is Crucial for Individual Patient-Care as Well as for Decision-Making of Healthcare Authorities. J Neurosci Rural Pract, 6(1), 4-5. doi: 10.4103/0976-3147.143164

Karch A, Castell S, Schwab F, Geffers C, Bongartz H, Brunkhorst FM, Gastmeier P & Mikolajczyk RT. (2015). Proposing an Empirically Justified Reference Threshold for Blood Culture Sampling Rates in Intensive Care Units. J Clin Microbiol, 53(2), 648-652. doi: 10.1128/jcm.02944-14

Karch A, Hermann P, Ponto C, Schmitz M, Arora A, Zafar S, Llorens F, Müller-Heine A, Zerr I. (2015). Cerebrospinal fluid tau levels are a marker for molecular subtype in sporadic Creutzfeldt-Jakob disease. Neurobiol Aging. 36(5):1964-8. doi: 10.1016/j.neurobiolaging.2015.01.021. Epub 2015 Feb 7.

Karch A, Schmitz RP, Rissner F, Castell S, Topel S, Jakob M, Brunkhorst FM & Mikolajczyk RT. (2015). Bloodstream Infections, Antibiotic Resistance and the Practice of Blood Culture Sampling in Germany: Study Design of a Thuringia-Wide Prospective Population-Based Study (Alertsnet). BMJ Open, 5(12), e009095. doi: 10.1136/bmjopen-2015-009095

Karch A, Vogel U, Claus H. (2015). Role of penA polymorphisms for penicillin susceptibility in Neisseria lactamica and Neisseria meningitidis. Int J Med Microbiol.305(7):729-35. doi: 10.1016/j.ijmm.2015.08.025. Epub 2015 Aug 21.

Maier IL, Karch A, Mikolajczyk R, Bahr M & Liman J. (2015). Effect of Beta-Blocker Therapy on the Risk of Infections and Death after Acute Stroke--a Historical Cohort Study. PLoS One, 10(2), e0116836. doi: 10.1371/journal.pone.0116836

McAlaney J, Helmer SM, Stock C, Vriesacker B, Van Hal G, Dempsey RC, Akvardar Y, Salonna F, Kalina O, Guillen-Grima F, Bewick BM & Mikolajczyk R. (2015). Personal and Perceived Peer Use of and Attitudes toward Alcohol among University and College Students in Seven Eu Countries: Project Snipe. J Stud Alcohol Drugs, 76(3), 430-438.

Mikolajczyk R, Horn J, Schmedt N, Langner I, Lindemann C & Garbe E. (2015). Injury Prevention by Medication among Children with Attention-Deficit/Hyperactivity Disorder: A Case-Only Study. JAMA Pediatr, 169(4), 391-395. doi: 10.1001/jamapediatrics.2014.3275

Murray CJ, […] Karch A, […] Lopez AD, Vos T. (2015). Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet, 386(10009):2145-91. doi: 10.1016/S0140-6736(15)61340-X. Epub 2015 Aug 28.

Naghavi M, Karch A, Murray CJ & Lopez A. (2015). Global, Regional, and National Age-Sex Specific All-Cause and Cause-Specific Mortality for 240 Causes of Death, 1990-2013: A Systematic Analysis for the Global Burden of Disease Study 2013. Lancet, 385(9963), 117-171. doi: 10.1016/S0140-6736(14)61682-2

Ohlmeier C, Hoffmann F, Giersiepen K, Rothgang H, Mikolajczyk R, Appelrat HJ, Elsasser A & Garbe E. (2015). [Linkage of Statutory Health Insurance Data with Those of a Hospital Information System: Feasible, but Also "Useful"?]. Gesundheitswesen, 77(2), e8-e14. doi: 10.1055/s-0034-1395644

Ohlmeier C, Langner I, Hillebrand K, Schmedt N, Mikolajczyk R, Riedel O & Garbe E. (2015). Mortality in the German Pharmacoepidemiological Research Database (Gepard) Compared to National Data in Germany: Results from a Validation Study. BMC Public Health, 15, 570. doi: 10.1186/s12889-015-1943-7

Ohlmeier C, Mikolajczyk R, Frick J, Prutz F, Haverkamp W & Garbe E. (2015). Incidence, Prevalence and 1-Year All-Cause Mortality of Heart Failure in Germany: A Study Based on Electronic Healthcare Data of More Than Six Million Persons. Clin Res Cardiol. doi: 10.1007/s00392-015-0841-4

Pischke CR, Helmer SM, McAlaney J, Bewick BM, Vriesacker B, Van Hal G, Mikolajczyk RT, Akvardar Y, Guillen-Grima F, Salonna F, Orosova O, Dohrmann S, Dempsey RC & Zeeb H. (2015). Normative Misperceptions of Tobacco Use among University Students in Seven European Countries: Baseline Findings of the 'Social Norms Intervention for the Prevention of Polydrug Use' Study. Addict Behav, 51, 158-164. doi: 10.1016/j.addbeh.2015.07.012

Raupach-Rosin H, Klett-Tammen CJ, Schmalz O, Karch A, Castell S & Mikolajczyk R. (2015). ["I Cannot Kiss My Wife"- an Analysis of Daily Experiences of Mrsa-Carriers]. Gesundheitswesen. doi: 10.1055/s-0035-1559710

Rubsamen N, Castell S, Horn J, Karch A, Ott JJ, Raupach-Rosin H, Zoch B, Krause G & Mikolajczyk RT. (2015). Ebola Risk Perception in Germany, 2014. Emerg Infect Dis, 21(6), 1012-1018. doi: 10.3201/eid2106.150013

Schweitzer A, Horn J, Mikolajczyk RT, Krause G & Ott JJ(2015). Estimations of Worldwide Prevalence of Chronic Hepatitis B Virus Infection: A Systematic Review of Data Published between 1965 and 2013. Lancet. doi: 10.1016/s0140-6736(15)61412-x

Vos T, […] Karch A, […] Salomon JA, Murray CJ. (2015). Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet, 386(9995):743-800. doi: 10.1016/S0140-6736(15)60692-4. Epub 2015 Jun 7.

Werfel T, Heratizadeh A, Niebuhr M, Kapp A, Roesner LM, Karch A, Erpenbeck VJ, Losche C, Jung T, Krug N, Badorrek P & Hohlfeld JM. (2015). Exacerbation of Atopic Dermatitis on Grass Pollen Exposure in an Environmental Challenge Chamber. J Allergy Clin Immunol. doi: 10.1016/j.jaci.2015.04.015

Ye J, Zhang J, Mikolajczyk R, Torloni MR, Gulmezoglu AM & Betran AP. (2015). Association between Rates of Caesarean Section and Maternal and Neonatal Mortality in the 21st Century: A Worldwide Population-Based Ecological Study with Longitudinal Data. Bjog. doi: 10.1111/1471-0528.13592

Zhang J, Mikolajczyk R, Lei X, Sun L, Yu H & Cheng W. (2015). An Adjustable Fetal Weight Standard for Twins: A Statistical Modeling Study. BMC Med, 13, 159. doi: 10.1186/s12916-015-0401-9

Zoch B, Karch A, Dreesman J, Monazahian M, Baillot A & Mikolajczyk RT. (2015). Feasibility of a Birth Cohort Study Dedicated to Assessing Acute Infections Using Symptom Diaries and Parental Collection of Biomaterials. BMC Infect Dis, 15, 436. doi: 10.1186/s12879-015-1189-0


Akmatov MK, Mehraj J, Gatzemeier A, Strompl J, Witte W, Krause G & Pessler F. (2014). Serial Home-Based Self-Collection of Anterior Nasal Swabs to Detect Staphylococcus Aureus Carriage in a Randomized Population-Based Study in Germany. Int J Infect Dis, 25, 4-10. doi: 10.1016/j.ijid.2014.01.021

Castell S, Akmatov MK, Obi N, Flesh-Janys D, Nieters A, Kemmling Y, Pessler F & Krause G. (2014). Test-Retest Reliability of an Infectious Disease Questionnaire and Evaluation of Self-Assessed Vulnerability to Infections : Findings of Pretest 2 of the German National Cohort. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 57(11), 1300-1307. doi: 10.1007/s00103-014-2045-x

Hechtner MC, Vogt T, Zollner Y, Schroder S, Sauer JB, Binder H, Singer S & Mikolajczyk R. (2014). Quality of Life in Parkinson's Disease Patients with Motor Fluctuations and Dyskinesias in Five European Countries. Parkinsonism Relat Disord, 20(9), 969-974. doi: 10.1016/j.parkreldis.2014.06.001

Helmer SM, Mikolajczyk RT, McAlaney J, Vriesacker B, Van Hal G, Akvardar Y, Guillen-Grima F, Salonna F, Stock C, Dempsey RC, Bewick BM & Zeeb H. (2014). Illicit Substance Use among University Students from Seven European Countries: A Comparison of Personal and Perceived Peer Use and Attitudes Towards Illicit Substance Use. Prev Med, 67, 204-209. doi: 10.1016/j.ypmed.2014.07.039

Hense S, Hillebrand K, Horn J, Mikolajczyk R, Schulze-Rath R & Garbe E. (2014). Hpv Vaccine Uptake after Introduction of the Vaccine in Germany: An Analysis of Administrative Data. Hum Vaccin Immunother, 10(6), 1729-1733. doi: 10.4161/hv.28450

Hille K, Mobius N, Akmatov MK, Verspohl J, Rabold D, Hartmann M, Gunther K, Obi N & Kreienbrock L. (2014). Zoonoses Research in the German National Cohort : Feasibility of Parallel Sampling of Pets and Owners. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 57(11), 1277-1282. doi: 10.1007/s00103-014-2047-8

Karch A, Krumkamp R & Kreuels B. (2014). Randomized, Placebo-Controlled Trial or Post Hoc Subgroup Analysis: The Importance of Standardized and Comprehensive Reporting. J Infect Dis. doi: 10.1093/infdis/jiu028

Karch A, Raddatz LM, Ponto C, Hermann P, Summers D & Zerr I. (2014). Diagnostic Profiles of Patients with Late-Onset Creutzfeldt-Jakob Disease Differ from Those of Younger Creutzfeldt-Jakob Patients: A Historical Cohort Study Using Data from the German National Reference Center. J Neurol261(5), 877-883. doi: 10.1007/s00415-014-7283-1

Karch A & Thomas SL. (2014). Autoimmune Thyroiditis as a Risk Factor for Stroke: A Historical Cohort Study. Neurology, 82(18), 1643-1652. doi: 10.1212/WNL.0000000000000377

Kassebaum NJ, […] Karch A, […] Murray CJ & Lozano R. (2014). Global, Regional, and National Levels and Causes of Maternal Mortality During 1990-2013: A Systematic Analysis for the Global Burden of Disease Study 2013. Lancet, 384(9947), 980-1004. doi: 10.1016/S0140-6736(14)60696-6

Kersting C, Lindemann C, Jacobi C, Lo Baido A, Schneider A, Yurdakul M, Ziegler-Kirbach E, Mikolajczyk R & Garbe E. (2014). [Therapy Goals for Children and Adolescents with Adhd and Their Primary Caregivers. A Content Analysis and Examination of Agreement of Adhd Patients and Their Primary Caregivers.]. Gesundheitswesen. doi: 10.1055/s-0034-1387746

Liman J, Deeg S, Voigt A, Voßfeldt H, Dohm CP, Karch A, Weishaupt J, Schulz JB, Bähr M, Kermer P. (2014). CDK5 protects from caspase-induced Ataxin-3 cleavage and neurodegeneration. J Neurochem. 2014 Jun;129(6):1013-23. doi: 10.1111/jnc.12684. Epub 2014 Mar 24.

Mall S, Akmatov MK, Schultze A, Ahrens W, Obi N, Pessler F & Krause G. (2014). Web-Based Questionnaires to Capture Acute Infections in Long-Term Cohorts : Findings of a Feasibility Study. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 57(11), 1308-1314. doi: 10.1007/s00103-014-2049-6

Mehraj J, Akmatov MK, Strompl J, Gatzemeier A, Layer F, Werner G, Pieper DH, Medina E, Witte W, Pessler F & Krause G. (2014). Methicillin-Sensitive and Methicillin-Resistant Staphylococcus Aureus Nasal Carriage in a Random Sample of Non-Hospitalized Adult Population in Northern Germany. PLoS One, 9(9), e107937. doi: 10.1371/journal.pone.0107937

Mikolajczyk RT, Horn J, Prins M, Wiessing L & Kretzschmar M. (2014). Trajectories of Injecting Behavior in the Amsterdam Cohort Study among Drug Users. Drug Alcohol Depend. doi: 10.1016/j.drugalcdep.2014.08.020

Minikel EV, Zerr I, Collins SJ, Ponto C, Boyd A, Klug G, Karch A, Kenny J, Collinge J, Takada LT, Forner S, Fong JC, Mead S & Geschwind MD. (2014). Ascertainment Bias Causes False Signal of Anticipation in Genetic Prion Disease. Am J Hum Genet, 95(4), 371-382. doi: 10.1016/j.ajhg.2014.09.003

Murray CJ, […] Karch A, […] Lopez AD & Vos T. (2014). Global, Regional, and National Incidence and Mortality for Hiv, Tuberculosis, and Malaria During 1990-2013: A Systematic Analysis for the Global Burden of Disease Study 2013. Lancet, 384(9947), 1005-1070. doi: 10.1016/S0140-6736(14)60844-8

Ohlmeier C, Frick J, Prutz F, Lampert T, Ziese T, Mikolajczyk R & Garbe E. (2014). [Use of Routine Data from Statutory Health Insurances for Federal Health Monitoring Purposes]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 57(4), 464-472. doi: 10.1007/s00103-013-1912-1

Ohlmeier C, Linder R, Enders D, Mikolajczyk R, Haverkamp W, Horenkamp-Sonntag D & Garbe E. (2014). Evaluating Methods for Intersectoral Comparison of Quality of Care. A Routine Data Analysis of Elective Percutaneous Coronary Interventions. Methods Inf Med, 53(4), 269-277. doi: 10.3414/ME13-01-0132

Schultze A, Akmatov MK, Andrzejak M, Karras N, Kemmling Y, Maulhardt A, Wieghold S, Ahrens W, Gunther K, Schlenz H, Krause G & Pessler F. (2014). Comparison of Stool Collection on Site Versus at Home in a Population-Based Study : Feasibility and Participants' Preference in Pretest 2 of the German National Cohort. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 57(11), 1264-1269. doi: 10.1007/s00103-014-2051-z

Schultze A, Akmatov MK, Castell S, Karch A, Ahrens W, Gunther K, Schlenz H, Flesch-Janys D, Obi N, Pessler F & Krause G. (2014). Collection of Vaccination Data in the German National Cohort : Findings of a Feasibility Study in Three Study Centers. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 57(11), 1292-1299. doi: 10.1007/s00103-014-2050-0

Sievers C, Akmatov MK, Kreienbrock L, Hille K, Ahrens W, Gunther K, Flesch-Janys D, Obi N, Michels KB, Fricke J, Greiser KH, Kaaks R, Peter HH, Pessler F, Nieters A & Krause G. (2014). Evaluation of a Questionnaire to Assess Selected Infectious Diseases and Their Risk Factors : Findings of a Multicenter Study. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 57(11), 1283-1291. doi: 10.1007/s00103-014-2052-y

Stich HL, Kramer A & Mikolajczyk RT(2014). Clustering of Developmental Delays in Bavarian Preschool Children - a Repeated Cross-Sectional Survey over a Period of 12 Years. BMC Pediatr, 14, 18. doi: 10.1186/1471-2431-14-18


Chu JJ, Wormann T, Popp J, Patzelt G, Akmatov MK, Kramer A & Reintjes R. (2013). Changing Epidemiology of Hepatitis B and Migration--a Comparison of Six Northern and North-Western European Countries. Eur J Public Health, 23(4), 642-647. doi: 10.1093/eurpub/cks067

Helmer S, Sebena R, McAlaney J, Petkeviciene J, Urban R & Mikolajczyk RT. (2013). Misperceptions of Peer Drinking Behaviour and Personal Alcohol Consumption among Students in Central and Eastern Europe. Paper presented at the Eur J Epidemiol. [Abstract] retrieved from

Horn J, Damm O, Kretzschmar ME, Delere Y, Wichmann O, Kaufmann AM, Garbe E, Kramer A, Greiner W & Mikolajczyk RT. (2013). Estimating the Long-Term Effects of Hpv Vaccination in Germany. Vaccine, 31(19), 2372-2380. doi: 10.1016/j.vaccine.2013.03.006

Karch A, Manthey H, Ponto C, Hermann P, Heinemann U, Schmidt C & Zerr I. (2013). Investigating the Association of Apoe Genotypes with Blood-Brain Barrier Dysfunction Measured by Cerebrospinal Fluid-Serum Albumin Ratio in a Cohort of Patients with Different Types of Dementia. PLoS One, 8(12), e84405. doi: 10.1371/journal.pone.0084405

Karch A & Zerr I. (2013). A Comparison of Tau and 14-3-3 Protein in the Diagnosis of Creutzfeldt-Jakob Disease. Neurology, 80(22), 2081. doi: 10.1212/01.wnl.0000431029.13491.59c

Langner I, Garbe E, Banaschewski T & Mikolajczyk RT(2013). Twin and Sibling Studies Using Health Insurance Data: The Example of Attention Deficit/Hyperactivity Disorder (Adhd). PLoS One, 8(4), e62177. doi: 10.1371/journal.pone.0062177

Mikolajczyk R, Kraut A & Garbe E. (2013). Evaluation of Pregnancy Outcome Records in the German Pharmacoepidemiological Research Database (Gepard). Pharmacoepidemiol Drug Saf, 22(8), 873-880. doi: 10.1002/pds.3467

Mikolajczyk RT, Helmer S, Wörmann T, Bhopal R, Rey G, Juel J, Regidor E, Deboosere P, Mackenbach JP & Kunst AE. (2013). Infectious Diseases Mortality among Migrants and Host Population in Five European Countries. Paper presented at the Eur J Epidemiol. [Abstract] retrieved from

Mikolajczyk RT, Kraut AA, Horn J, Schulze-Rath R & Garbe E. (2013). Changes in Incidence of Anogenital Warts Diagnoses after the Introduction of Human Papillomavirus Vaccination in Germany-an Ecologic Study. Sex Transm Dis, 40(1), 28-31. doi: 10.1097/OLQ.0b013e3182756efd

Mikolajczyk RT, Prins M, Wiessing L & Kretzschmar M. (2013). Trajectories of Injecting Behaviour in the Amsterdam Cohort Study among Drug Users. Eur J Epidemiol, 28(Suppl 1), S13-14.

Mikolajczyk RT, Schmedt N, Zhang J, Lindemann C, Langner I & Garbe E. (2013). Regional Variation in Caesarean Deliveries in Germany and Its Causes. BMC Pregnancy Childbirth, 13, 99. doi: 10.1186/1471-2393-13-99

Ohlmeier C, Mikolajczyk R, Haverkamp W & Garbe E. (2013). Incidence, Prevalence, and Antithrombotic Management of Atrial Fibrillation in Elderly Germans. Europace. doi: 10.1093/europace/eut048

Samkange-Zeeb F, Mikolajczyk RT & Zeeb H. (2013). Awareness and Knowledge of Sexually Transmitted Diseases among Secondary School Students in Two German Cities. J Community Health, 38(2), 293-300. doi: 10.1007/s10900-012-9614-4

Schmidt C, Karch A, Artjomova S, Hoeschel M & Zerr I. (2013). Pre-Progression Rates in Alzheimer's Disease Revisited. J Alzheimers Dis, 35(3), 451-454. doi: 10.3233/JAD-130074

Wasser K, Karch A, Groschel S, Witzenhausen J, Groschel K, Bahr M & Liman J. (2013). Plaque Morphology Detected with Duplex Ultrasound before Carotid Angioplasty and Stenting (Cas) Is Not a Predictor of Carotid Artery in-Stent Restenosis, a Case Control Study. BMC Neurol, 13, 163. doi: 10.1186/1471-2377-13-163

Zakar R, Zakar MZ, Mikolajczyk R & Kraemer A. (2013). Spousal Violence against Women and Its Association with Women's Mental Health in Pakistan. Health Care Women Int, 34(9), 795-813. doi: 10.1080/07399332.2013.794462


Akmatov M, Mikolajczyk R, Krumkamp R, Wörmann T, Chu J, Paetzelt G, Reintjes R, Pessler F & Krämer A. (2012). Availability of Indicators of Migration in the Surveillance of Hiv, Tuberculosis and Hepatitis B in the European Union – a Short Note. Journal of Public Health, 20(5), 483-486. doi: 10.1007/s10389-011-0488-1

Akmatov MK, Gatzemeier A, Schughart K & Pessler F. (2012). Equivalence of Self- and Staff-Collected Nasal Swabs for the Detection of Viral Respiratory Pathogens. PLoS One, 7(11), e48508. doi: 10.1371/journal.pone.0048508

Akmatov MK & Mikolajczyk RT. (2012). Timeliness of Childhood Vaccinations in 31 Low and Middle-Income Countries. J Epidemiol Community Health, 66(7), e14. doi: 10.1136/jech.2010.124651

Helmer SM, Kramer A & Mikolajczyk RT. (2012). Health-Related Locus of Control and Health Behaviour among University Students in North Rhine Westphalia, Germany. BMC Res Notes, 5, 703. doi: 10.1186/1756-0500-5-703

Mikolajczyk RT, Horn J, Damm O, Kaufmann AM & Kretzschmar ME(2012). Re: Epidemiological Study of Anti-Hpv-16/18 Seropositivity and Subsequent Risk of Hpv-16 and -18 Infections. J Natl Cancer Inst, 104(2), 163; author reply 163-164. doi: 10.1093/jnci/djr517

Mikolajczyk RT, Kraut AA, Horn J, Schulze-Rath R & Garbe E. (2012). Auswirkungen Der Hpv-Impfung Auf Die Inzidenz Von Anogenitalen Warzen – Eine Auswertung Von Abrechnungsdaten Einer Krankenkasse. Paper presented at the DGEpi 2012, Regensburg 26.-29.09.

Pischke CR, Zeeb H, van Hal G, Vriesacker B, McAlaney J, Bewick BM, Akvardar Y, Guillen-Grima F, Orosova O, Salonna F, Kalina O, Stock C, Helmer SM & Mikolajczyk RT(2012). A Feasibility Trial to Examine the Social Norms Approach for the Prevention and Reduction of Licit and Illicit Drug Use in European University and College Students. BMC Public Health, 12, 882. doi: 10.1186/1471-2458-12-882

Rapp D, Zoch B, Khan MM, Pollmann T & Kramer A. (2012). Association between Gap in Spousal Education and Domestic Violence in India and Bangladesh. BMC Public Health, 12, 467. doi: 10.1186/1471-2458-12-467

Samkange-Zeeb F, Mikolajczyk RT & Zeeb H. (2012). Awareness and Knowledge of Sexually Transmitted Diseases among Secondary School Students in Two German Cities. J Community Health. doi: 10.1007/s10900-012-9614-4

Schmidt C, Karch A, Korth C & Zerr I. (2012). On the Issue of Transmissibility of Alzheimer Disease: A Critical Review. Prion, 6(5), 447-452. doi: 10.4161/pri.22502

Stoeck K, Sanchez-Juan P, Gawinecka J, Green A, Ladogana A, Pocchiari M, Sanchez-Valle R, Mitrova E, Sklaviadis T, Kulczycki J, Slivarichova D, Saiz A, Calero M, Knight R, Aguzzi A, Laplanche JL, Peoc'h K, Schelzke G, Karch A, van Duijn CM & Zerr I. (2012). Cerebrospinal Fluid Biomarker Supported Diagnosis of Creutzfeldt-Jakob Disease and Rapid Dementias: A Longitudinal Multicentre Study over 10 Years. Brain, 135(Pt 10), 3051-3061. doi: 10.1093/brain/aws238


Akmatov MK. (2011). Child Abuse in 28 Developing and Transitional Countries--Results from the Multiple Indicator Cluster Surveys. Int J Epidemiol, 40(1), 219-227. doi: 10.1093/ije/dyq168

Akmatov MK, Krebs S, Preusse M, Gatzemeier A, Frischmann U, Schughart K & Pessler F. (2011). E-Mail-Based Symptomatic Surveillance Combined with Self-Collection of Nasal Swabs: A New Tool for Acute Respiratory Infection Epidemiology. Int J Infect Dis, 15(11), e799-803. doi: 10.1016/j.ijid.2011.07.005

Akmatov MK, Mikolajczyk RT, Meier S & Kramer A. (2011). Alcohol Consumption among University Students in North Rhine-Westphalia, Germany--Results from a Multicenter Cross-Sectional Study. J Am Coll Health, 59(7), 620-626. doi: 10.1080/07448481.2010.520176

Akmatov MK & Pessler F. (2011). Self-Collected Nasal Swabs to Detect Infection and Colonization: A Useful Tool for Population-Based Epidemiological Studies? Int J Infect Dis, 15(9), e589-593. doi: 10.1016/j.ijid.2011.04.009

von Jagwitz M, Pessler F, Akmatov M, Li J, Range U & Vogelberg C. (2011). Reduced Breath Condensate Ph in Asymptomatic Children with Prior Wheezing as a Risk Factor for Asthma. J Allergy Clin Immunol, 128(1), 50-55. doi: 10.1016/j.jaci.2011.03.005