Structure and Function of Proteins
Structural biologists aim at deriving an understanding of the molecular basis of biological phenomena by obtaining images of the involved biomacromolecules at atomic resolution. We use protein crystallography to investigate proteins that play a role in infectious disease, e.g. by controlling the production of toxic molecules or by acting as toxins themselves. Our research in structural biology is complemented by biochemical and biophysical methods, and we also employ all these technologies to aid drug discovery projects at the HZI.