News

• 05.07.2017

  Molecular "Trojan horses" render infections visible

  

  Some pathogenic bacteria cause infections that are a serious health risk. Due to the ever increasing international mobility, this infection risk will continue to rise in the future. In addition, modern medical treatments that penetrate through biological barriers of the body and weaken the immune system are a serious problem. Another reason for concern is the fact that the fraction…

• 31.03.2015

  Joining forces in the search for an agent against MRSA

  

  Hospital-acquired germs are a steadily increasing problem in Germany. This is the case because many of these germs are resistant to most of the conventional antibiotics. Therefore, there is an urgent need for new agents. In this search, scientists from the Helmholtz Centre for Infection Research (HZI) in Braunschweig and of the Lead Discovery Center (LDC) Dortmund have joined forces…

• 03.09.2012

  Drug researchers’ valuable “bycatch“

  

  The natural substance eliamid is capable of suppressing cancer cell proliferation – so far in the test tube. Produced by certain strains of soil bacteria, the substance was re-cently characterized by a group of scientists at the Helmholtz Centre for Infection Re-search (HZI) in Braunschweig, Germany. Now, Dr. Evgeny Prusov and his team are sharing their insights into why they consider…

• 08.07.2008

  Argyrin: natural substance raises hope for new cancer therapies

  

  The effective treatment of many forms of cancer continues to pose a major problem for medicine. Many tumours fail to respond to standard forms of chemotherapy or become resistant to the medication. Scientists at the Helmholtz Centre for Infection Research (HZI) in Braunschweig, the Hannover Medical School (MHH) and Leibniz-Universität (LUH) in Hanover have now discovered a chemical…

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Video

• Epothilon: Ein HZI-Molekül wird zum Krebsmedikament

  Wissenschaftler an der ehemaligen Gesellschaft für Biotechnologische Forschung (GBF), dem heutigen HZI, haben in den 1980er Jahren Epothilon B entdeckt. Dieser Naturstoff stört die Teilung von Krebszellen: Tumore werden durch ihn im Wachstum gebremst, schrumpfen und verschwinden. Das Pharmaunternehmen Bristol-Myers Squibb (BMS) hat jetzt auf der Basis von Epothilon B ein Krebsmedikament auf den US-amerikanischen Markt gebracht. Seine Entwicklung ist so spannend wie ein Krimi...
  Länge: 11:34

• Molecular Trojan Horses Visualize Infections

  Researchers from the Helmholtz Centre for Infection Research (HZI) and the German Center for Infection Research (DZIF) recently developed molecular probes that utilise the iron transport system of bacteria to transport antibacterial agents into the bacterial cell. These "molecular Trojan horses" can also carry fluorescence markers and thus make infections in smaller animals visible and amenable to treatment. Kevin Ferreira explains here the new developed method in a minute.

Audio Podcast

• Kleine Moleküle ganz groß – Mit Naturstoffen gegen Hepatitis CMit weltweit 130 Millionen Infizierten ist Hepatitis C eine der häufigsten Infektionskrankheiten. Die Therapien, die es derzeit gibt, sind langwierig, haben starke Nebenwirkungen und helfen nicht jedem Patienten. Florenz Sasse vom Braunschweiger Helmholtz-Zentrum für Infektionsforschung und Thomas Pietschmann vom TWINCORE in Hannover suchen gemeinsam nach neuen Wirkstoffen gegen das Hepatitis C-Virus. Hören Sie hier von ihren ersten Treffern und folgen Sie Florenz Sasse zu einer Bibliothek der anderen Art…