NMR-based structural chemistry

To be able to develop new drugs against infectious diseases we need to uncover their molecular basis. Therefore it is essential to understand how pathogens replicate, how they interact with the host and how these processes are regulated. The research group NMR-based structural chemistry investigates RNA_protein complexes involved in various aspects of infection, from both the pathogens and hosts life cycle. 

Prof Dr Teresa Carlomagno

Teresa Carlomagno started her scientific career at the University of Naples, Italy. During her Ph.D. studies and her following post-doctoral work at the University of Frankfurt, Germany, she developed NMR methods to study the structure and the dynamics of proteins, nucleic acids and small molecules. During a second post-doctoral period at The Scripps Research Institute, La Jolla, USA, she matured a strong interest in the mechanisms of intermolecular recognition and function in ribonucleoprotein complexes.

In 2001, she joined the Max Planck Institute for Biophysical Chemistry in Göttingen, Germany, and started her own research group. In 2007, she moved to the EMBL in Heidelberg as a group leader in biomolecular NMR spectroscopy in the Structural and Computational Biology Unit. Her research program focuses on two areas: half of the laboratory studies the structural basis for the function of ribonucleoprotein (RNP) complexes with catalytic activity in RNA metabolism and gene regulation; the other half of the laboratory studies the interaction of small molecules with macromolecular receptors and develops NMR-based methodologies for drug design. Interdisciplinarity and advanced technology are key elements to her vision for structural biology.

In 2015 she will move to the Leibniz University of Hannover, as a W3 professor in Structural Chemistry. She is a joined group leader at the HZI in Braunschweig. 

Leader

  • Prof Dr Teresa Carlomagno

    Head of the research group

    +49 531 6181-7300

    Contact