Microbial Drugs

The majority of the medically important antibiotic drugs (including e.g., penicillins, cephalosporins, erythromycin, vancomycin, and daptomycin) are derived from secondary metabolites, which are produced by bacteria and filamentous fungi. Despite intensive world-wide efforts using alternative approaches based on synthetic chemistry, no other concept could so far surpass the historically successful strategy to exploit biologically active natural products as candidates for anti-infective drugs. The recently observed, increasing resistance of the human pathogens against antibiotics has prompted us to intensify our search for novel lead structures from microorganisms and fungi, which can be used as anti-infective drugs.

Leader

Team

Dr Enge Sudarman

Scientist

Curriculum Vitae

since February  2012
Post Doctorate Researcher in the department of Microbial Drugs, Helmholtz Center for Infection Research

Projects:

  • Isolation and structure elucidation of secondary metabolites of myxobacteria and actinomycetes
  • Analysis and isolation of fungal pigments in fruit-bodies

June 2007
Ph.D. in Bioorganic Chemistry

Thesis: Design, synthesis and analysis of bindings characteristics from inhibitors of interaction of viral Interleukin-6 with the cytokine receptor gp130


July 2002 - Dec. 2006

PhD student in the group of Conformational Protein-Ligand Interaction, Helmholtz Center for Infection Research, Braunschweig


June 2001 - Dec. 2001
Study of English Language, Bristol, England


April  2001
Second state examination and probation as a Food Chemist


April 2000 – March 2001
Practical  year for Food Chemists, State Government Laboratories in Braunschweig and Lüneburg


1995 - 2000
Studies of Food Chemistry, TU Braunschweig
First state examination


1994 - 1995
Niedersächsisches  Studienkolleg, Hannover


1992 - 1993
Study of Chemical Engineering at Tung Hai University, Taiwan

Mycology

Microbiology

Natural Product Chemistry

Fermentation

Microbial Strain Collection

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