Microbial Drugs

The majority of the medically important antibiotic drugs (including e.g., penicillins, cephalosporins, erythromycin, vancomycin, and daptomycin) are derived from secondary metabolites, which are produced by bacteria and filamentous fungi. Despite intensive world-wide efforts using alternative approaches based on synthetic chemistry, no other concept could so far surpass the historically successful strategy to exploit biologically active natural products as candidates for anti-infective drugs. The recently observed, increasing resistance of the human pathogens against antibiotics has prompted us to intensify our search for novel lead structures from microorganisms and fungi, which can be used as anti-infective drugs.

Team

    Christian Richter

    Christian Richter

    PhD Student

    +49 531 6181-4235

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    Curriculum Vitae

    Since 01/2013   
    PhD student in the department of Prof. Dr. Marc Stadler, Helmholtz Centre for Infection Research, Braunschweig, Germany
    2012                 
    master thesis in the working group of Prof. Dr. Dominik Begerow Title: “Investigation of antimicrobial metabolites from epiphyllic yeasts on maize”
    2005-2012       
    study of biology at the Ruhr-University Bochum (focus on biodiversity)

     

    Abstract
    Basidiomycetes have been known to produce bioactive compounds for a long time, mutilins and strobilurins being examples for lead compounds that have even gained great commercial success. However, discovery of novel antibiotics and other useful compounds has so far been mainly restricted to the fruitbody-forming “macrofungi”. Over 90% of the Basidiomycetes remain unexploited for bioactive metabolites. My project targets the Ustilaginomycotina, a hyperdiverse subdivision of the basidiomycetes that has already yielded unique compounds like glycolipids in the past.

Mycology

  • Clara Chepkirui

    Clara Chepkirui

    PhD Student

    +49 531 6181-4244

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  • Sandra Halecker

    Sandra Halecker

    PhD Student

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    CV and Publications

  • Wilawan Kuephadungphan

    Wilawan Kuephadungphan

    PhD Student

    +49 531 6181-4225

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  • Juan Sebastian Lopez

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    Visiting PhD Student

    +49 531 6181-4225

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  • Sarah Raouia Noumeur

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    Visiting PhD Student

    +49 531 6181-4225

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  • Christian Richter

    Christian Richter

    PhD Student

    +49 531 6181-4235

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    CV and Publications

  • Lucile Wendt

    Lucile Wendt

    PhD Student

    +49 531 6181-4244

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  • Simone Heitkämper

    Simone Heitkaemper

    Research Assistant

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  • Kathrin Pommerehne

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    Master Student

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  • Jennifer Weber

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    Bachelor Student

    + 49 531 6181-4224

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  • Jan-Peer Wennrich

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    Bachelor Student

    + 49 531 6181-4253

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  • Anke Skiba

    Anke Skiba

    Technical Assistant

    +49 531 6181-4225

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  • Christopher Lambert

    Christopher Lambert

    Student Assistant

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  • Anne Weiß

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    Student assistant

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Microbiology

Natural Product Chemistry

Fermentation

  • Dr Stephan Hüttel

    Stephan Huettel

    Scientist

    +49 531 6181-4237

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  • Dipl.-Ing. Steffen Bernecker

    Steffen Bernecker

    Engineer

    +49 531 6181-4246

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  • Amelie Beckmann

    Amelie Beckmann

    PhD Student

    +49 531 6181-4263

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  • Zeljka Rupcic

    Zeljka Rupcic

    PhD Student

    +49 531 6181-4244

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  • Burkhard Ebert

    Technical Assistant

    +49 531 6181-4249

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  • Andrew Perreth

    Andrew Perreth

    Technical Assistant

    +49 531 6181-4243

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  • Axel Schulz

    Axel Schulz

    Technical Assistant

    +49 531 6181-4250

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  • Cäcilia Schwager

    Caecilia Schwager

    Technical Assistent

    +49 531 6181-4224

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  • Reinhard Sterlinski

    Reinhard Sterlinski

    Technical Assistant

    +49 531 6181-4250

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  • Lisa Hoffmann

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    Bachelor Student

    + 49 531 6181-4263

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  • Steve Möller

    Bachelor Student

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Microbial Strain Collection

To the team page

Guests and Former Members

  • Dr Klaus Gerth

    Klaus Gerth

    Scientist

    +49 531 6181-4261

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  • Dr Ignacio Poblete-Castro

    Ignacio Poblete-Castro

    Scientist

    + 49 531 6181-4261

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  • Dipl.-Ing. Wolfgang Kessler

    Wolfgang Kessler

    Engineer

    +49 531 6181-4237

    +49 531 6181-9499

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  • Vincent Wiebach

    +49 531 6181-4225

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  • Benjarong Thonbai (Zine)

    Benjarong Thongbai

    PhD Student

    +49 531 6181-4225

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  • Dr Andre Luis Rodrigues

    Andre Luis Rodrigues

    Postdoc

    +49 531 6181-4238

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  • Dr Kathrin Bohle

    Kathrin Bohle

    Scientist

    +49 531 6181-4237

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  • Dr Smita Bhuyan

    Scientist

    +49 531 6181-4244

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  • Samad Ashrafi

    PhD of JKI

    0531 6181-4235

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  • Pia Philine Wotsch

    Pia Philine Wotsch

    Technical Assistant

    +49 531 6181-4244

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  • Dr Eric Kuhnert

    PostDoc

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  • Nadine Wurzler

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    Bachelor Student

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Leader

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Bachelor & Master
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