Drug Delivery

This group is located at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

While considering the confusing flood of drugs in the pharmacies it is hard to believe in a lack of medication. But there are still many infectious diseases and also cancer that cannot be treated sufficiently. During a medical treatment it is essential that the drug arrives at the envisaged body region. Read more about the research of the department “Drug Delivery” on techniques for the correct distribution of novel drugs.

Leader

Selected Publications

Lehr CM, Bouwstra JA, Schacht EH, Junginger HE (1992) in vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers. Int J Pharm 78: 43–48 

Elbert KJ, Schäfer UF, Schäfers HJ, Kim KJ, Lee VHL, Lehr CM (1999) Monolayers of human alveolar epithelial cells in primary culture for pulmonary absorption and transport studies. Pharm Res 16: 601–608 

Lamprecht A, Schäfer UF, Lehr CM (2001) Size-dependent bioadhesion of micro- and nanoparticulate carriers to the inflamed colonic mucosa. Pharm Res 18: 788–793 

Ravi Kumar MNV, Bakowsky U, Lehr CM (2004) Preparation and characterization of cationic PLGA nanospheres as DNA carriers. Biomaterials 25: 1771–1777 

Lademann J, Richter H, Teichmann A, Otberg N, Blume-Peytavi U, Luengo J, Weiß B, Schäfer UF, Lehr CM, Wepf R, Sterry W (2007) Nanoparticles - An efficient carrier for drug delivery into the hair follicles. Eur J Pharm Biopharm 66: 159–164 

Publications

Full publications list of Claus-Michael Lehr (PDF)

DDEL publications  from 2010 to date (PDF)

Claus-Michael Lehr - 10 most cited papers (PDF)

News

Bachelor & Master
Are you interested in a bachelor or master thesis? We are looking forward to your request!

Video

  • HIPS Infofilm (English)

    Resistance to antibiotics has become one of the major global challenges regarding infectious diseases. This is specifically the issue that is being tackled by the new Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS).

Audio Podcast

  • Kleine Teile – große Wirkung: Pharmazeuten des HIPS schleusen Medikamente zielsicher durch den Körper Wie kommt ein Medikament dahin, wo es wirken soll? Das ist eine der zentralen Fragen bei der Entwicklung neuer Wirkstoffe. Denn es reicht nicht, ein tolles neues Medikament gegen Darminfektionen im Reagenzglas zu haben – es muss auch dort hin gelangen, wo die Krankheit stattfindet. Mit Transportmolekülen schleusen die Pharmazeuten des HZI diese Wirkstoffe durch unseren Körper – über Barrieren, durch passende Lücken und an gefährlichen Stellen vorbei. Besuchen Sie Claus-Michael Lehr und Brigitta Loretz am Helmholtz-Institut für Pharmazeutische Forschung Saarland (HIPS)…
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