Transregional Collaborative Research Center (Transregio-SFB) Roseobacter

Project C5: Systems biology of the environmental adaptation of Dinoroseobacter shibae

The goal of this project is to obtain a theoretical understanding of two important adaptation strategies: The use of light as an additional energy source, and phenotypic heterogeneity of an isogenic population. Phenotypical heterogeneity was shown in roseobacters for bacteriochlorophyll synthesis, cell morphology, mode of cell division, flagella formation, type IV secretion, and synthesis of the gene transfer agent. In D. shibae it is under the control of quorum sensing, and non-heterogeneous mutants are available. Heterogeneity can also be induced by cultivation conditions. Selection for different phenotypes will be studied in different experimental systems (biofilm, alga-bacterium interaction, protozoan grazing) to identify potential underlying bet-hedging strategies. Evolutionary models will be constructed from these data. 

Partners

Carl von Ossietzky Universität Oldenburg

Institut für Chemie und Biologie des Meeres

Technische Universität Braunschweig

Institut für Mikrobiologie
Institut für Organische Chemie
Abteilung für Bioinformatik und Biochemie
Institut für Bioverfahrenstechnik

Leibniz-Institut DSMZ - Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH

Mikrobiologie
Molekulare Systematik

Göttingen Genomics Laboratory

Abteilung Genomische und Angewandte Mikrobiologie

Leader

  • Prof Dr Irene Wagner-Döbler

    Irene Wagner-Döbler

    Head of the Research Group Microbial Communication

    +49 531 6181-3080

    +49 531 6181-3096

    Contact

    CV and Publications

Groups

Speaker

Prof Dr D. Jahn, Dr Richard Münch

Homepage

http://www.roseobacter.tu-bs.de/en/projectC5

Funding Agency

DFG - German Research Foundation