SFB 578

Development of Biotechnological Processes by Integrating Genetic and Engineering Methods – From Gene to Product

The Collaborative Research Center SFB 578 "Development of Biotechnological Processes by Integrating Genetic and Engineering Methods – From Gene to Product –", aims at combining and integrating methods available both from the basic sciences and the fundamental engineering sciences, notably genetics and biochemical engineering, to obtain high value-added products. The work primarily concerns processes for the microbial production of new heterologous proteins by recombinant production strains. The bacteria Escherichia coli (gram-negative) and Bacillus megaterium (gram-positive) as well as the mycelium-forming fungus Aspergillus niger are used as host organisms. The products under study are either pharmaceutically active (antibodies, bone morphogenetic proteins) or serve as biocatalysts to synthesize new oligosaccharides.

Partners

Institut für Pharmazeutische Technologie, TU Braunschweig

Institut für Mikrotechnik, TU Braunschweig

Institut für Mikrobiologie, TU Braunschweig

Institut für Biochemie und Biotechnologie, TU Braunschweig

Institut für Partikeltechnik, TU Braunschweig

Helmholtz Zentrum für Infektionsforschung GmbH, Abt. Strukturbiologie

Institut für Bioverfahrenstechnik, TU Braunschweig

Helmholtz Zentrum für Infektionsforschung GmbH, Zelluläre Proteomforschung

Institut für Elektrische Messtechnik und Grundlagen der Elektrotechnik, TU Braunschweig

Institut für Technische Chemie, TU Braunschweig

Institut für Organische Chemie, Würzburg

Institut für Verfahrenstechnik, Otto-von-Guericke-Universität Magdeburg

Groups

Speaker

Prof. Dr. Dieter Jahn

Homepage

www.sfb578.tu-braunschweig.de

Funding Agency

DFG - German Research Foundation