Proteomic characterization of distinct NK cell maturation stages
NK cells are cytotoxic lymphocytes and can be subdivided into distinct subsets of different maturation stages due to their presentation of certain surface antigens like CD56, CD57 and CD3. Our aim is the proteomic characterization of these distinct primary NK cell subsets isolated from healthy human blood donors in order to get a deeper insight into the mechanisms of cytotoxicity and differentiation on a molecular level by using quantitative LC-MS/MS techniques.
- Cellular Proteome Research - Prof. Dr. Lothar Jänsch
Maxi Scheiter (Helmholtz-Zentrum für Infektionsforschung)