Research Projects (Third party funds)
Investigation of the influence of the sequence and load of infections and vaccinations during childhood on the development of the immunesystem (ongoing project)
Within the birth cohort study LöwenKIDS, we want to investigate the influence of the sequence and load of infections and vaccinations during childhood on the development of the immune system. At birth, theimmune system is not yet fully developed. It needs to get in contact with infectious agents to be able to develop adequate defense mechanisms against them.
That is one reason for children being more likely to get sick than adults. Vaccines can stimulate the immune system to develop defense mechanisms against certain diseases without suffering from the actual disease.
However, the immune system does not always develop in the optimal way. For example, in case of anallergy the immune system responds to rather harmless substances like pollen, cat fur or peanuts and mistakes them for harmful pathogens. Sometimes the immune system even attacks cells of the own body, for example at certain forms of diabetes mellitus.
Those diseases often become apparent at adulthood, but their origin can be found in the patient’s childhood. We want to investigate the influence these research questions within LöwenKIDS in greater detail.
For further information about the LöwenKIDS study click here.
- Day nurseries Braunschweig
- Local health authority of Lower Saxony, Hannover
- Research group Microbial Interactions and Processes, Helmholtz-Centre for Infection Research, Braunschweig
- Research group Microbial Communication, Helmholtz-Centre for Infection Research, Braunschweig
- BaBi-Team of the Bielefeld University
- Research group Vaccinology, Helmholtz-Centre for Infection Research, Braunschweig
- Vaccinology - Prof. Dr. Carlos A. Guzmán