Ubiquitin and Ubiquitin-like host modifications in Listeria infection
Although it is known that ubiquitin and ubiquitin-like modifiers are utilized during invasion of Listeria monocytogenes, the underlying mechanisms are only sparsely described. Therefore, a systematic and protein-based approach to retrieve a detailed insight in the ubiquitin-mediated processes shall be established in this project. In combination with a subsequent functional characterization of candidate proteins, this study will provide working points for the specific impairment or inhibition of cell invasion by Listeria.
- Cellular Proteome Research - Prof. Dr. Lothar Jänsch
Anne Kummer (Helmholtz-Zentrum für Infektionsforschung)