Model Systems for Infection and Immunity

In infection research experiments on cells and mice have a pivotal role. Frequently such model systems have to be tailored to allow tackling a specific scientific question. To this end, genetic modification of cell lines and mice is being pursued.

Leader

Prof Dr Dagmar Wirth
Contact
Head of the Research Group Model Systems for Infection and Immunity
+49 531 6181-5040
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Technology Offers

The following technologies have been developed and patented by the group Model Systems for Infection and Immunity:

New viral packaging cell line

Mouse models for liver immunity and therapeutic vaccinations

News

2021-07-15
Vaccination success without B cells
Autoimmune diseases, such as rheumatoid arthritis or multiple sclerosis, in which the body's own immune system causes inflammation, are treated with drugs that remove a certain type of immune cells. These are the so-called B cells, whose most important role is the production of antibodies against pathogens, for example during an infection. However, patients under therapy are thus…
2018-11-02
2018 Technology Transfer Award goes to an HZI spin-off company
Before a newly detected agent, used to fight for example a bacterial or viral pathogen, can be approved for use as medication, it must pass various test studies: The first pre-clinical studies are done on cell cultures and animals, after which follow several clinical studies using humans. The time from the discovery of the agent to production of the actual medicine may take from ten…
2018-03-08
Immortal cells for tailor-made active substances
Scientists need primary body cells for many investigations, screenings of new agents and active substance tests. These cells originate directly from the respective tissue or organ. However, biopsies yield only small numbers of cells that are insufficient for broad screenings. For example: Although it is possible to obtain blood vessel-producing endothelial cells from umbilical…

Bachelor & Master
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The Strategy of the HZI

Research report 2020/2021

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Feature: Coronaviruses

SARS-CoV-2 / COVID-19

Model Systems for Infection and Immunity

Leader

Prof Dr Dagmar Wirth

Technology Offers

News

Vaccination success without B cells

2018 Technology Transfer Award goes to an HZI spin-off company

Immortal cells for tailor-made active substances