Immune Regulation
Due to their physiological functions our mucosal surfaces are in direct contact to the environment and thus represent the major port of entry for pathogens. To protect the body from severe infections an effective mucosal immune system is indispensable. We are studying respiratory tract infections with the focus on influenza and pneumococci, which represent the most frequent viral and bacterial infectious agents for pneumonia in humans. A major focus of our research is to study molecular and cellular processes during coinfection with influenza and pneumococci and here in particular the immunological functions of the alveolar epithelium in host defense.
Leader
Research Projects
- Establishment of novel interventional strategies for influenza (co)infection by experimental analyses and mathematical modeling of infection : MODELING INFLUENZA AND COINFECTION
- Analysing influenza A virus-mediated changes in the reactivity of alveolar type II epithelial cells as an underlying mechanism of increased susceptibility to secondary pneumococcal infections : AECII AND COINFECTION
- Long-term effects of preceding influenza A virus infection on myeloid cells along the lung-bone marrow-axis.
- Human mucosal-associated invariant T (MAIT) cells in age-associated Clostridioides difficile infections : ESF-GS ABINEP / TEILPROJEKT M3.P6
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Bachelor & Master
Are you interested in a bachelor or master thesis? We are looking forward to your request!