Due to their physiological functions our mucosal surfaces are in direct contact to the environment and thus represent the major port of entry for pathogens. To protect the body from severe infections an effective mucosal immune system is indispensable. We are studying respiratory tract infections with the focus on influenza and pneumococci, which represent the most frequent viral and bacterial infectious agents for pneumonia in humans. A major focus of our research is to study molecular and cellular processes during coinfection with influenza and pneumococci and here in particular the immunological functions of the alveolar epithelium in host defense.
- Analysing influenza A virus-mediated changes in the reactivity of alveolar type II epithelial cells as an underlying mechanism of increased susceptibility to secondary pneumococcal infections : AECII AND COINFECTION
- Establishment of novel interventional strategies for influenza (co)infection by experimental analyses and mathematical modeling of infection : MODELING INFLUENZA AND COINFECTION
- Long-term effects of preceding influenza A virus infection on myeloid cells along the lung-bone marrow-axis.
- Elucidating the roles of secretory immunoglobulins in asthma under homeostatic and infectious conditions: ESF-GS ABINEP / TEILPROJEKT M3.P5
- Human mucosal-associated invariant T (MAIT) cells in age-associated Clostridioides difficile infections : ESF-GS ABINEP / TEILPROJEKT M3.P6
- Role of IκBNS in lung tissue regeneration after influenza A virus infection and its potential impact on lethal synergism between influenza and bacterial pathogens during superinfection: IΚBNS IN TISSUE REGENERATION FOLLOWING INFLUENZA INFECTION
- The role of the atypical NF-κB inhibitory protein IκBNS in effector cells: SFB 854, TEILPROJEKT A23
- Impact of acute influenza infection on cancer development
Bachelor & Master
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