Computational Biology for Individualised Medicine

Infections are among the biggest threats to health and the most significant causes of death worldwide. Our aim is to reveal the host genetic risk factors and their downstream molecular pathways, which are crucial to make progress in understanding and treating infectious diseases in an individualised manner as well as to improve the identification of patients at risk. The department is part of the developing CiiM and currently housed at the TWINCORE in Hannover.


People are different in genetic background. We study this inter-individual variation and want to understand susceptibility to infections and predict disease risk

Prof Dr Yang Li

Prof. Dr. Yang Li

Yang Li received her doctoral degree of bioinformatics in 2010 from the University of Groningen, the Netherlands. She continued her career as a postdoc at the Groningen Bioinformatics Centre and she received the Young Investigator Award of Bioinformatics from the Netherlands Bioinformatics Centre in 2011.

She then became a principal investigator / assistant professor in the Department of Genetics at the University Medical Centre Groningen. Her successful research on systems genetics of immune-related diseases was awarded with two personal grants: the VENI (Dutch Organization for Scientific Research, 2013) and the Off-Road (the Netherlands Organisation for Health Research and Development, 2016). In 2018, Yang Li received the prestigious “Hypatia Grant” from the Radboud University Medical Center.

Since 2019, Yang Li heads the Department of Computational Biology of Individualised Infection Medicine at the Helmholtz Centre for Infection Research / Centre for Individualised Infection Medicine in Hannover.

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