Cellular Proteome Research
This platform provides full service as well as proteome-scaled research in collaborative projects. We combine expertise in biochemistry, mass spectrometry (MS) and biostatistics matching the demands in translational research and systems level approaches. The platform focuses on the characterization of proteins that are the functional players in infections and our prime targets in drug research. The platform contributes to the discovery of novel drug-targets in pathogen-host interactions and cellular signaling pathways that coordinate the course of infections.
The platform utilizes modern MS workflows including Orbitrap (Velos Pro & ETD-Fusion), SILAC-, iTRAQ- and TMT labeling technologies and various in house software packages and databases (e.g. ProteomDiscoverer, MaxQuant, OpenMS). Bioinformatics and Biostatistics in clinical and translational projects is further supported by the project of Prof. Frank Klawonn and our collaboration with Prof. O. Schilling and Dr. Lars Nilse (Institute of Molecular Medicine and Cell Research, Freiburg). Proteome analyses can be started with a minimum of 2x10E5 sorted cells.
- Dr. Manfred Nimtz
- Dr. Josef Wissing
- Prof. Dr. Lothar Jänsch
Bachelor & Master
Are you interested in a bachelor or master thesis? We are looking forward to your request!