Cellular Proteome Research

Pathogenic bacteria and viruses utilize and manipulate cellular processes of our immune system. The identification of protein functions in the human immune system that decisively control the progression of infections constitutes the central aim of the research group Cellular Proteomics at the HZI.

Leader

Prof Lothar Jänsch

Proteins are the functional and druggable units in infection. An unbiased examination of protein networks allows us to identify the most relevant players in immunity and infection.

Lothar Jänsch

Lothar Jänsch studied biology at the Free University of Berlin and in 1995 prepared his diploma thesis at the IGF in Berlin. After that, he worked as a PhD student at the IGF and the University of Hanover and graduated in 1998.

After two years of working as a scientific consultant for the Pfizer Company, Germany, Lothar Jänsch started as a postdoc in the Department of Cell Biology at the German Research Centre for Biotechnology (GBF) in 2000.

From 2003 to 2006 he headed the project “Identification of new virulence factors” and since 2009 is the head of the research group “Cellular Proteomics” at the Helmholtz Centre for Infection Research (HZI). Together with the Technical University Braunschweig he was then appointed in 2011 as W2 professor for Proteome research of infectious processes.

His research focuses on translational projects in cooperation with academic, medical and industrial partners to investigate host-pathogen interactomes and mechanisms of control in immune responses.

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