Immune Response and Interventions

The focus of Topic "Immune Response and Interventions" is the response of the immune system to infections. Scientists in this Topic study the recognition of bacteria and viruses by the immune system, the reasons for individual susceptibility towards infections and the mechanisms pathogens use to circumvent the host’s immune system. They explore the immune system’s ageing, the influence of microbial communities in the body on the course of infections and the impact of infections on neurodegenerative diseases. These activities span the range from fundamental studies in cells and in animal models, up to human studies performed in cooperation with clinical partners using patient and population cohorts. The insights gained serve as the basis for new immune-focused strategies for prevention, e.g. by vaccination, and for the treatment of infectious diseases.