Structure and Function of Proteins
Structural biology is a powerful method to derive an understanding of the molecular basis of biological phenomena by visualizing the involved biomacromolecules at atomic resolution. The Department Structure and Function of Proteins uses protein crystallography to investigate proteins that play a role in infectious disease, e.g. by controlling the production of toxic molecules or by acting as toxins themselves. Our research in structural biology is complemented by biochemical and biophysical methods, and we employ all of these technologies to also aid drug discovery projects at the HZI.
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Ongoing Research Projects
- Helmholtz Drug Research Initiative: DRUG RESEARCH
- Graduate School Protein Complex Assembly (PROCOMPAS): Maturation of nitrite reductase NirS through interaction with NirF and NirN
- Collaborative Research Consortium CDInfect - Adaptation strategies of Clostridioides difficile during host infection: Structure and function of protein interaction networks required for infection with C. difficile
Expired Research Projects
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